AutismKB 2.0

Annotation Detail for STC1


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Basic Information Top
Gene Symbol:STC1 ( STC )
Gene Full Name: stanniocalcin 1
Band: 8p21.2
Quick LinksEntrez ID:6781; OMIM: 601185; Uniprot ID:STC1_HUMAN; ENSEMBL ID: ENSG00000159167; HGNC ID: 11373
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C422565 13beta-methyl 19-nor-steroid 13beta-methyl 19-nor-steroid inhibits the reaction [Progesterone results in increased expression of STC1 mRNA]decreases reaction|increases expression 16452456
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of STC1 mRNAincreases expression 19933214
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of STC1 mRNAdecreases expression 18648102
D000643 Ammonium Chloride Ammonium Chloride affects the expression of STC1 mRNAaffects expression 16483693
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of STC1 mRNAincreases expression 18687144
C031463 beta-glycerophosphoric acid beta-glycerophosphoric acid results in decreased expression of STC1 mRNAdecreases expression 17438129
C006780 bisphenol A bisphenol A affects the expression of STC1 mRNAaffects expression 20170705
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of STC1 mRNAincreases expression 15336504
D016572 Cyclosporine Cyclosporine results in decreased expression of STC1 mRNAdecreases expression 20106945
C004742 daidzein [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of STC1 mRNAaffects cotreatment|decreases expression 16963248
D004958 Estradiol [Progesterone co-treated with Estradiol] results in decreased expression of STC1 mRNAaffects cotreatment|decreases expression 17404688
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of STC1 mRNAaffects expression 20170705
D017245 Foscarnet Foscarnet results in increased expression of STC1 mRNAincreases expression 17438129
D019833 Genistein [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of STC1 mRNAaffects cotreatment|decreases expression 16963248
D019833 Genistein Genistein results in increased expression of STC1 mRNAincreases expression 12075121
C086566 glycitein [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of STC1 mRNAaffects cotreatment|decreases expression 16963248
D007213 Indomethacin Indomethacin results in decreased expression of STC1 mRNAdecreases expression 17401462
C016599 mono-(2-ethylhexyl)phthalate mono-(2-ethylhexyl)phthalate results in increased expression of STC1 mRNAincreases expression 16809437
C030110 oxaliplatin oxaliplatin results in decreased expression of STC1 mRNAdecreases expression 17762391
D017239 Paclitaxel STC1 protein affects the susceptibility to Paclitaxelaffects response to substance 16217747
D010656 Phenylephrine Phenylephrine affects the expression of STC1 mRNAaffects expression 18158353
D010795 Phthalic Acids Phthalic Acids results in increased expression of STC1 mRNAincreases expression 15728792
C006253 pirinixic acid pirinixic acid results in increased expression of STC1 mRNAincreases expression 12832660
D011374 Progesterone [Progesterone co-treated with Estradiol] results in decreased expression of STC1 mRNAaffects cotreatment|decreases expression 17404688
D011374 Progesterone Progesterone results in decreased expression of STC1 mRNAdecreases expression 17404688
D011374 Progesterone 13beta-methyl 19-nor-steroid inhibits the reaction [Progesterone results in increased expression of STC1 mRNA]decreases reaction|increases expression 16452456
D011374 Progesterone CSH1 protein promotes the reaction [Progesterone results in increased expression of STC1 mRNA]increases expression|increases reaction 16452456
D011374 Progesterone GH1 protein promotes the reaction [Progesterone results in increased expression of STC1 mRNA]increases expression|increases reaction 16452456
D011374 Progesterone Progesterone results in increased expression of STC1 mRNAincreases expression 16452456
D011374 Progesterone Progesterone results in decreased expression of STC1decreases expression 17510236
D011794 Quercetin Quercetin results in increased expression of STC1 mRNAincreases expression 19729006
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of STC1 mRNAincreases expression 19933214
D019772 Topotecan STC1 protein affects the susceptibility to Topotecanaffects response to substance 16217747
C066075 vanadium pentoxide vanadium pentoxide results in increased expression of STC1 mRNAincreases expression 17459161
D014810 Vitamin E Vitamin E results in decreased expression of STC1 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.6115322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.3118287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6917505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.8918653653
MESH:D000230 Adenocarcinoma daidzein 12.8811473722
MESH:D000230 Adenocarcinoma Estradiol 12.8811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.8814692618
MESH:D000230 Adenocarcinoma Genistein 12.8811473722
MESH:D000230 Adenocarcinoma Indomethacin 12.8816537180
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.423712494
MESH:D000236 Adenoma Indomethacin 6.4211497255
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.0816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.0816835633
MESH:D017088 AIDS-Related Opportunistic Infections Foscarnet 6.4711363124
MESH:D016301 Alveolar Bone Loss Indomethacin 5.1217225004
MESH:D000544 Alzheimer Disease Indomethacin 2.6515579461 17627676
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7311748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.0217084956
MESH:D001014 Aortic Aneurysm Indomethacin 4.6110231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.6310388637
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.9017460149
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2211256880
MESH:D018771 Arthralgia Indomethacin 4.922160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5115885639
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.7711248219
MESH:D001260 Ataxia Telangiectasia Quercetin 4.7315336622
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 4.2020106747
MESH:D001327 Autoimmune Diseases Quercetin 4.1719761891
MESH:D001477 Bartter Syndrome Indomethacin 4.7410684365
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.771440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.0419483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.0412125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6115746008
MESH:D001859 Bone Neoplasms Paclitaxel 4.3415867366
MESH:D001862 Bone Resorption bisphenol A 3.6411985600
MESH:D001919 Bradycardia Phenylephrine 4.3015306635
MESH:D001929 Brain Edema Indomethacin 4.7811481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.0917868700
MESH:D001930 Brain Injuries Progesterone 4.0215845082 15380490 15665606
MESH:D002545 Brain Ischemia Indomethacin 4.1712524144
MESH:D001943 Breast Neoplasms bisphenol A 4.5317123778
MESH:D001943 Breast Neoplasms Estradiol 4.5318497071 16675129 19861407 12948864 17018787 17289903 17261762 14630087
MESH:D001943 Breast Neoplasms Genistein 4.5316873071 16541309 17200150
MESH:D001943 Breast Neoplasms Indomethacin 4.5317401462
MESH:D001943 Breast Neoplasms Paclitaxel 4.5315136595 18234424 16115903 16244791 18323546 18223236 11325840 16273361
MESH:D001943 Breast Neoplasms Progesterone 4.5315562024 16175315 17614352
MESH:D001943 Breast Neoplasms Quercetin 4.5318628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.5320435547
MESH:D001991 Bronchitis vanadium pentoxide 5.9917459161
MESH:D002056 Burns Indomethacin 4.4610459503
MESH:D002100 Cachexia Indomethacin 4.7615141370 11239499 16537180 15625704
MESH:D002105 Cadmium Poisoning Quercetin 5.3016962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.2216111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.6916050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6116835633
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 10.857296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Estradiol 10.8516924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 10.8516924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 10.8516391822
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 10.8516313753
MESH:D006528 Carcinoma, Hepatocellular Quercetin 10.8519519916 12508355
MESH:D002278 Carcinoma in Situ bisphenol A 4.7417123778
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.4811053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.1018791128 11352223 14736730
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.7117234771
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 6.247296757
MESH:D002292 Carcinoma, Renal Cell Indomethacin 6.2417341418
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 2.7812636206 15482327
MESH:D006332 Cardiomegaly Phenylephrine 10.6911754973 11179087 17287366 17124262 15728586 16170337
MESH:D006332 Cardiomegaly Quercetin 10.6919794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 10.6916120746 18850075 18670907
MESH:D002318 Cardiovascular Diseases daidzein 7.2416332659
MESH:D002318 Cardiovascular Diseases Genistein 7.2416332659
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 10.177505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.1712371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.1718566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.9616835633
MESH:D002764 Cholecystitis Indomethacin 4.9211181007
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 17.7419486331 9022650
MESH:D002779 Cholestasis Cyclosporine 17.7419486331
MESH:D002779 Cholestasis Ethinyl Estradiol 17.7417681005 15861022 16105132 17333356 16919318 17110522 11677210
MESH:D002779 Cholestasis pirinixic acid 17.7419176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.008697196 12621046 16354765 15340226 15668235
MESH:D003110 Colonic Neoplasms Genistein 7.9917182828
MESH:D003110 Colonic Neoplasms Indomethacin 7.9915963497 11260862 15637740 15786552 15625704 15936596
MESH:D003110 Colonic Neoplasms oxaliplatin 7.9916024531 16004971 16510598
MESH:D003110 Colonic Neoplasms Quercetin 7.9919440933 19056647 17148506 15741050 11134977 16640504 17191121
MESH:D015179 Colorectal Neoplasms Indomethacin 4.7012606626 17054584 11197048 18059344
MESH:D015179 Colorectal Neoplasms oxaliplatin 4.7018509181 18448328 17594712 17255274 17401013 17695437
MESH:D015179 Colorectal Neoplasms Paclitaxel 4.7018802399
MESH:D015179 Colorectal Neoplasms Quercetin 4.7018852136 18095365
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8514669216 17141729
MESH:D018352 Coronavirus Infections Indomethacin 5.4717302372
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4020055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.4019769572
MESH:D003586 Cytomegalovirus Infections Foscarnet 6.618781616 11050094
MESH:D017726 Cytomegalovirus Retinitis Foscarnet 6.6311363124
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.5711298694 12868966 8970840 14531868 18759878 2524372 11906362 8156756
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3118249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.263621924 2952479
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.5319496084
MESH:D003924 Diabetes Mellitus, Type 2 daidzein 6.9016647724
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.9016647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.9017107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.2119279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.2517187935
MESH:D003967 Diarrhea Indomethacin 3.567237001 7907874
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 3.451440618 11289319 7440962 18692083 9328219 9653073 6679447 8291058 16192314 18289764 6482804 18648102 9022650
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.4520420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5811462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.9016133044 12774134 16326151 18043480 17190690 18446180
MESH:D004381 Duodenal Ulcer Indomethacin 3.9011535926 10671773 17351913 17151854 11595431 17045617 11991626 17329845 17202747 16699067 11595415
MESH:C538011 Eales disease Vitamin E 4.459068938
MESH:D004487 Edema Indomethacin 10.1819703484 7907874 8985016 16100529 8273558 10653021 7990266
MESH:D004487 Edema pirinixic acid 10.1812083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.1811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6516714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.2512538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 8.2517692515
MESH:D004714 Endometrial Hyperplasia Genistein 4.3416402032
MESH:D016889 Endometrial Neoplasms daidzein 11.7111473722
MESH:D016889 Endometrial Neoplasms Estradiol 11.7111473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Genistein 11.7111473722
MESH:D004715 Endometriosis Indomethacin 14.0715652904
MESH:D004715 Endometriosis Progesterone 14.0716134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 14.0710568697 9294722
MESH:D019446 Endotoxemia Indomethacin 4.2518509659
MESH:D004751 Enteritis Indomethacin 4.5010567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.7417980183
MESH:D004802 Eosinophilia Indomethacin 3.8111298111
MESH:D007172 Erectile Dysfunction daidzein 4.7814972507
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.013581430
MESH:D004938 Esophageal Neoplasms Indomethacin 7.0111005569
MESH:D004938 Esophageal Neoplasms Paclitaxel 7.0116481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8311564622
MESH:D005234 Fatty Liver Cyclosporine 11.7319224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 11.7315345470
MESH:D005234 Fatty Liver pirinixic acid 11.7320131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2111858732
MESH:D005334 Fever Indomethacin 3.9111852909 10431976 17627676
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.776705139
MESH:D005354 Fibrosarcoma Indomethacin 4.6510962813
MESH:D005355 Fibrosis Cyclosporine 19.1912639820 12168785
MESH:D005355 Fibrosis Indomethacin 19.1917994277
MESH:D005355 Fibrosis Quercetin 19.1919474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 19.1920067830
MESH:D005499 Folliculitis Indomethacin 4.9211298111
MESH:D005756 Gastritis Indomethacin 4.5015046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.978708960
MESH:D005909 Glioblastoma Genistein 11.0916598420
MESH:D005909 Glioblastoma Indomethacin 11.0912870263
MESH:D005909 Glioblastoma Quercetin 11.0919804834
MESH:D005910 Glioma Indomethacin 5.9916487511 18371953
MESH:D005910 Glioma Quercetin 5.9917643826
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.0911849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.817505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3410696789
MESH:D006073 Gout Indomethacin 5.1011248219
MESH:D006258 Head and Neck Neoplasms Indomethacin 3.5815482327
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.1410048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 6.1416080930
MESH:D006333 Heart Failure pirinixic acid 2.3920558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1715720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1211000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.3515633222
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.286705139
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.4515135802
MESH:D006529 Hepatomegaly pirinixic acid 7.4616221962 18467677 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.4615340226 12621046 16120746
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6216863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.7815709030
MESH:D015658 HIV Infections Foscarnet 4.9611362904 11050094
MESH:D019584 Hot Flashes Estradiol 9.2217088409
MESH:D019584 Hot Flashes Vitamin E 9.2214716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.808697196 15340226 16354765 16959395 18606429
MESH:D006930 Hyperalgesia Indomethacin 7.8012727271
MESH:D006930 Hyperalgesia oxaliplatin 7.8017418472
MESH:D034321 Hyperamylasemia Indomethacin 5.4717883296
MESH:D006940 Hyperemia Indomethacin 4.7612524144
MESH:D006943 Hyperglycemia pirinixic acid 8.5320558911
MESH:D006943 Hyperglycemia Quercetin 8.5318262572 11834736
MESH:D006949 Hyperlipidemias Indomethacin 3.9417546600
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.7015034207
MESH:D006973 Hypertension Cyclosporine 15.4010903974
MESH:D006973 Hypertension daidzein 15.4017169123
MESH:D006973 Hypertension Phenylephrine 15.4012717712 8949925
MESH:D006973 Hypertension Quercetin 15.4018356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 15.4018850075 18670907
MESH:D006984 Hypertrophy Phenylephrine 4.3318502941 12791704
MESH:D007015 Hypophosphatemia, Familial Foscarnet 7.188948520
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5716945680 16569931
MESH:D007077 Ileal Diseases Indomethacin 4.7810574470 18306037
MESH:D007079 Ileitis Indomethacin 5.1010651667 16133968 10647630
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.1216133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.1615869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2312013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3317937319
MESH:D007249 Inflammation Indomethacin 7.643291741 12568917 7812673
MESH:D007249 Inflammation Progesterone 7.6415869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.6412200463 12878042
MESH:D007251 Influenza, Human Quercetin 10.2416624496
MESH:D007251 Influenza, Human Vitamin E 10.2416624496
MESH:D007333 Insulin Resistance bisphenol A 11.4016393666
MESH:D007333 Insulin Resistance Estradiol 11.4016627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 11.4016306350
MESH:D007410 Intestinal Diseases Indomethacin 4.0811713966 11686837 17329856 11855677 17994277 15831440 18236018 15610444 10210152
MESH:D019586 Intracranial Hypertension Indomethacin 5.1215241188
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.778074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1216580747
MESH:D007579 Jejunal Diseases Indomethacin 4.7818306037 16133968 10574470
MESH:D007627 Keloid Quercetin 4.7117086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1915604871
MESH:D007674 Kidney Diseases Cyclosporine 17.578314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 17.5715618244
MESH:D007674 Kidney Diseases Indomethacin 17.5717190690
MESH:D007674 Kidney Diseases Quercetin 17.5716962696
MESH:D007674 Kidney Diseases Vitamin E 17.5712488133
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.226582329
MESH:D007680 Kidney Neoplasms Cyclosporine 11.2212371664
MESH:D007680 Kidney Neoplasms Estradiol 11.2215610895
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.7110320625 12228301 11703811
MESH:D007938 Leukemia Genistein 6.1518980019 17468513
MESH:D007938 Leukemia Quercetin 6.1517468513
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.7516572323 15631656 10785260
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 2.5918360721
MESH:D007964 Leukocytosis Indomethacin 5.1216537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.4717980183
MESH:D008080 Liposarcoma Paclitaxel 4.5917353645
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.4711479899
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.0415034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 10.4214659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 10.4217823541
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 10.4218194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.4215474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 10.4212741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.4212878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 10.4216169303
MESH:D008113 Liver Neoplasms pirinixic acid 6.8415890375 16377806 20007298
MESH:D008113 Liver Neoplasms Quercetin 6.8418980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 6.8416984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 8.96598648 6587162 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental Quercetin 8.9619519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 8.9612151625
MESH:D008171 Lung Diseases Vitamin E 3.0116863852
MESH:D055370 Lung Injury Asbestos, Crocidolite 3.7817365036
MESH:D008175 Lung Neoplasms Indomethacin 6.2911497255 11053908 16537180
MESH:D008175 Lung Neoplasms Quercetin 6.2916280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.2911884234 19555203
MESH:D008175 Lung Neoplasms vanadium pentoxide 6.2912376484
MESH:D008175 Lung Neoplasms Vitamin E 6.2911062179
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.8914749477
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 9.1111408345 16891317 17203775 11807958
MESH:D008325 Mammary Neoplasms, Experimental Genistein 9.1114578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 9.1117203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.2319453300
MESH:D008545 Melanoma Paclitaxel 2.5612025231 16342250 12040289
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.0916166281 16966607 18303189
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5416801185
MESH:D008881 Migraine Disorders Indomethacin 3.5011903285
MESH:D009062 Mouth Neoplasms Indomethacin 3.8012636206
MESH:D009101 Multiple Myeloma Paclitaxel 3.5214749477
MESH:D009135 Muscular Diseases pirinixic acid 3.2716239165
MESH:D009203 Myocardial Infarction Genistein 8.8917141266
MESH:D009203 Myocardial Infarction pirinixic acid 8.8919151258
MESH:D009203 Myocardial Infarction Quercetin 8.8919595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 18.7616810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 18.7617141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 18.7616411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 18.7619207477
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 9.063581430
MESH:D009362 Neoplasm Metastasis Indomethacin 9.0611053908 11239499 16537180
MESH:D009362 Neoplasm Metastasis Paclitaxel 9.0615867366
MESH:D009369 Neoplasms pirinixic acid 4.6517405874
MESH:D009369 Neoplasms Quercetin 4.6515185748
MESH:D009374 Neoplasms, Experimental Indomethacin 3.9010663608 15625704
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4917289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0819348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 21.5111399458 16427766
MESH:D009421 Nervous System Malformations Estradiol 21.5116427766 11399458
MESH:D009421 Nervous System Malformations Genistein 21.5116427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 21.5114600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.766679447
MESH:D009447 Neuroblastoma Topotecan 3.7215176712
MESH:D019636 Neurodegenerative Diseases Indomethacin 3.7412349958
MESH:D020078 Neurogenic Inflammation Quercetin 4.1317929310
MESH:D009765 Obesity pirinixic acid 1.7520558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.926374098
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.216482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.773988306
MESH:D010003 Osteoarthritis Indomethacin 3.527009135
MESH:D010014 Osteolysis Paclitaxel 4.7315867366
MESH:D010024 Osteoporosis Genistein 3.1019401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 9.3816169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 9.3819495926
MESH:D010049 Ovarian Diseases bisphenol A 4.7411985600
MESH:D010051 Ovarian Neoplasms Estradiol 14.1519401270
MESH:D010051 Ovarian Neoplasms Genistein 14.1519005980
MESH:D010051 Ovarian Neoplasms Paclitaxel 14.1511161223
MESH:D010051 Ovarian Neoplasms Progesterone 14.1517393432 16525653
MESH:D010051 Ovarian Neoplasms Quercetin 14.1519005980
MESH:D010146 Pain Indomethacin 3.2717627676 13679232 17440234 3291741
MESH:D010149 Pain, Postoperative Indomethacin 4.4318702446 12538197
MESH:D010190 Pancreatic Neoplasms Quercetin 2.7616965848
MESH:D010195 Pancreatitis Indomethacin 3.7015028970 17883296
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4611578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.247296757
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.4716537180
MESH:D020734 Parkinsonian Disorders Indomethacin 3.9112349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.4711903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0012520081
MESH:D010437 Peptic Ulcer Indomethacin 4.9011148446
MESH:D010518 Periodontitis Indomethacin 4.6617225004
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.226228378
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.6510923243
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3218163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.4212371664
MESH:D011230 Precancerous Conditions Quercetin 8.4219056647
MESH:D047928 Premature Birth Indomethacin 4.8817000239
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 8.6910548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.6911118676 11896295 11222880 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.8220887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.8220887781
MESH:D011471 Prostatic Neoplasms bisphenol A 1.8816740699
MESH:D011471 Prostatic Neoplasms Estradiol 1.8816740699
MESH:D011471 Prostatic Neoplasms Genistein 1.8815256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms Paclitaxel 1.8816729912 16356831 17172428 17136230
MESH:D011471 Prostatic Neoplasms Quercetin 1.8814715546 17292933
MESH:D011471 Prostatic Neoplasms Vitamin E 1.8815084515
MESH:D011507 Proteinuria Indomethacin 3.9411849393
MESH:D011537 Pruritus Ethinyl Estradiol 3.0715861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1416882103
MESH:D011629 Puberty, Precocious bisphenol A 4.5410548101
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 2.9417365031 17322281 17975199 15814490
MESH:D015427 Reperfusion Injury pirinixic acid 2.2719058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6018990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.193692021
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7718045962
MESH:D012554 Schistosomiasis japonica Quercetin 5.3016862918
MESH:D012852 Sinusitis Phenylephrine 4.467327846
MESH:D012871 Skin Diseases Vitamin E 2.3818709164
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 5.218532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.2116192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.6916709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.0315862959 16503802
MESH:D013272 Stomach Diseases Indomethacin 4.1715038085 16113693 17160473 18209964 10215738 17207306 10486359 17638125 16280098 10192188 18545984 16184426 15472012
MESH:D013274 Stomach Neoplasms Indomethacin 2.8115609394
MESH:D013274 Stomach Neoplasms Paclitaxel 2.8118506536 18396642
MESH:D013276 Stomach Ulcer Indomethacin 3.3716934674 16755016 17657623 15255614 18209962 1323529 16169175 10750652 17895592 15104355 10423059 12500499 18193104 11523592 11595431 18431645 18181030 18299717 17654042 11595415 10878458 18237397 12787963 17627676 17977527 16252198 18726076 17135157 16150113 11729361 17918041 18087811 11906479 12077510 12498302 15138204 11145282 12467913 16397915 14567935 16631530 18543354
MESH:D020521 Stroke Vitamin E 3.3316517955
MESH:D019966 Substance-Related Disorders bisphenol A 3.7416684133 16045194
MESH:D024801 Tauopathies Paclitaxel 4.5716930453
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3911994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6512697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 6.731399818 6582329 3712494 6587162 7505956
MESH:D013964 Thyroid Neoplasms Indomethacin 6.7314736730 18791128 11352223
MESH:D013978 Tibial Fractures Estradiol 4.4419048282
MESH:D014456 Ulcer Indomethacin 4.6510574470 17380554
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 4.888074119
MESH:D001749 Urinary Bladder Neoplasms Quercetin 4.8816720314
MESH:D014591 Uterine Diseases bisphenol A 4.7614652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.0614692618
MESH:D014605 Uveitis Cyclosporine 3.731336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3412125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3215869587 14671159
MESH:D014839 Vomiting Indomethacin 4.5011897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0015886252
MESH:D014985 Xerophthalmia Cyclosporine 4.1917120751
No data
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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