AutismKB 2.0

Annotation Detail for STXBP3


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Basic Information Top
Gene Symbol:STXBP3 ( MUNC18-3,MUNC18C,PSP,UNC-18C )
Gene Full Name: syntaxin binding protein 3
Band: 1p13.3
Quick LinksEntrez ID:6814; OMIM: 608339; Uniprot ID:STXB3_HUMAN; ENSEMBL ID: ENSG00000116266; HGNC ID: 11446
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Hemostasis
No data
No data
Pathway IDPathway Name
500941Disinhibition of SNARE formation
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of STXBP3 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of STXBP3 mRNAaffects expression 21346803
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of STXBP3 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of STXBP3 mRNAaffects expression 16483693
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1918287403
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.8616705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.8616705839
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 4.8621507988 12619106 12907637
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.036135515
MESH:D003490 Cyanosis 2,4-dinitrotoluene 12.8318551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 12.8318551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 4.1618551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.1621346803 18551238
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.5316705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.5316705839
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 5.017678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 5.0115890375 9163691 2125692 18177683
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 6.732876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 6.738603461
MESH:D008175 Lung Neoplasms Aflatoxin B1 1.8814755239
MESH:D009336 Necrosis 2,4-dinitrotoluene 12.5418551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 12.547678174 18551238
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 10.2312819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 10.2316049721
MESH:D012640 Seizures 2,4-dinitrotoluene 6.7418551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.7418551238
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.4316049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.4316049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 14.1910091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 14.1910091137
Pathway ID Pathway Name
REACT:604 Hemostasis
Pharmacogenomics Knowledge Base Top
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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