Annotation Detail for SUPT6H
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of SUPT6H mRNA | affects expression | 21346803
|
| C035207 |
4-amino-2,6-dinitrotoluene |
4-amino-2,6-dinitrotoluene affects the expression of SUPT6H mRNA | affects expression | 21346803
|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of SUPT6H mRNA | affects expression | 17562736
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
4-amino-2,6-dinitrotoluene |
4.69 | 7525203 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.71 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.39 | 18445737 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
2.97 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
2.97 | 3084413 |
| MESH:D002386 |
Cataract |
|
4-amino-2,6-dinitrotoluene |
8.19 | 14694615 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
8.19 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
3.06 | 6135515 |
| MESH:D000013 |
Congenital Abnormalities |
|
4-amino-2,6-dinitrotoluene |
4.58 | 15095906 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
4.67 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
6.87 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
4-amino-2,6-dinitrotoluene |
6.87 | 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
6.87 | 16109766 12540782 16393943 19416960 12153990 19739265 11743745 11529661 11421492 18071297 19923254 11739529 2444490 11461765 18713872 12958197 16485898 17906064 16177239 10915739 19420014 14550746 19164858 16781746 15968718 11287661 10774834 14725611 17562736 12705907 12392966 12594235 14986274 11834606 16081117 15619225 10663392 16227642 19085960 17522070 19370779 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.96 | 19426721 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.54 | 16983495 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.06 | 16870215 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.42 | 15629191 12587719 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
3.36 | 16705839 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.71 | 19460945 16610002 19014921 12969438 19784758 11587558 12587719 16611625 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.68 | 16871587 17185352 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.28 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.79 | 6135515 2876786 2876784 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.22 | 19513568 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
4.60 | 18551238 7678174 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.26 | 18514411 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
10.66 | 16049721 |
| MESH:D009784 |
Occupational Diseases |
|
4-amino-2,6-dinitrotoluene |
10.66 | 14694615 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.77 | 16870215 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
2.82 | 18551238 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
2.42 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
5.06 | 10091137 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.50 | 10982225 |
Related Pathway Information