Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
---|
C027576 |
4-hydroxy-2-nonenal |
4-hydroxy-2-nonenal results in decreased expression of SYP mRNA | decreases expression | 12419474
|
C106538 |
abacavir |
abacavir results in increased expression of SYP protein | increases expression | 19358275
|
D020106 |
Acrylamide |
Acrylamide results in increased expression of SYP protein | increases expression | 15864552
|
C041524 |
aluminum sulfate |
aluminum sulfate results in decreased expression of SYP mRNA | decreases expression | 15961160
|
D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of SYP mRNA | affects expression | 16483693
|
C072553 |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AGT protein results in increased degradation of SYP protein] | decreases reaction|increases degradation | 18487452
|
D002713 |
Chlorine |
[Ozone co-treated with Chlorine] results in increased expression of SYP mRNA | affects cotreatment|increases expression | 18636392
|
D020111 |
Chlorodiphenyl (54% Chlorine) |
Chlorodiphenyl (54% Chlorine) results in decreased expression of SYP protein | decreases expression | 17229471
|
D020111 |
Chlorodiphenyl (54% Chlorine) |
IL6 gene mutant form inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of SYP protein] | decreases expression|decreases reaction | 17229471
|
D020111 |
Chlorodiphenyl (54% Chlorine) |
Chlorodiphenyl (54% Chlorine) results in increased expression of SYP protein | increases expression | 16174552
|
C010902 |
decabromobiphenyl ether |
decabromobiphenyl ether metabolite results in increased expression of SYP protein | increases expression | 19380496
|
D003907 |
Dexamethasone |
Dexamethasone results in increased expression of SYP protein | increases expression | 15965953
|
D005038 |
Ethylnitrosourea |
Ethylnitrosourea results in increased mutagenesis of SYP gene | increases mutagenesis | 16495775
|
D005473 |
Fluoxetine |
Fluoxetine results in increased expression of SYP mRNA | increases expression | 17950272
|
D006830 |
Hydralazine |
[Hydralazine co-treated with Valproic Acid] results in increased expression of SYP mRNA | affects cotreatment|increases expression | 17183730
|
D006861 |
Hydrogen Peroxide |
Hydrogen Peroxide results in decreased expression of SYP mRNA | decreases expression | 12419474
|
C067713 |
lactacystin |
lactacystin inhibits the reaction [AGT protein results in increased degradation of SYP protein] | decreases reaction|increases degradation | 18487452
|
D008770 |
Methylnitrosourea |
Methylnitrosourea affects the expression of SYP protein | affects expression | 18155124
|
D010126 |
Ozone |
[Ozone co-treated with Chlorine] results in increased expression of SYP mRNA | affects cotreatment|increases expression | 18636392
|
C093973 |
PD 98059 |
PD 98059 inhibits the reaction [AGT protein results in increased degradation of SYP protein] | decreases reaction|increases degradation | 18487452
|
D013311 |
Streptozocin |
Streptozocin results in increased expression of SYP mRNA | increases expression | 18487452
|
D013311 |
Streptozocin |
telmisartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein] | decreases expression|decreases reaction | 18487452
|
D013311 |
Streptozocin |
valsartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein] | decreases expression|decreases reaction | 18487452
|
C013690 |
styrene oxide |
styrene oxide results in decreased expression of SYP protein | decreases expression | 17662326
|
C084178 |
telmisartan |
telmisartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein] | decreases expression|decreases reaction | 18487452
|
C084178 |
telmisartan |
telmisartan inhibits the reaction [AGT protein results in decreased expression of SYP protein] | decreases expression|decreases reaction | 18487452
|
C084178 |
telmisartan |
telmisartan inhibits the reaction [AGT protein results in increased ubiquitination of SYP protein] | decreases reaction|increases ubiquitination | 18487452
|
D013749 |
Tetrachlorodibenzodioxin |
Tetrachlorodibenzodioxin results in decreased expression of SYP mRNA | decreases expression | 19465110
|
D024505 |
Tocopherols |
Tocopherols results in increased expression of SYP mRNA | increases expression | 17654050
|
D014212 |
Tretinoin |
[Tretinoin co-treated with SHH protein co-treated with FGF8 protein] results in increased expression of SYP protein | affects cotreatment|increases expression | 17085092
|
C113580 |
U 0126 |
U 0126 inhibits the reaction [AGT protein results in increased degradation of SYP protein] | decreases reaction|increases degradation | 18487452
|
D014635 |
Valproic Acid |
[Hydralazine co-treated with Valproic Acid] results in increased expression of SYP mRNA | affects cotreatment|increases expression | 17183730
|
C081489 |
valsartan |
valsartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein] | decreases expression|decreases reaction | 18487452
|
C081489 |
valsartan |
valsartan inhibits the reaction [AGT protein results in decreased expression of SYP protein] | decreases expression|decreases reaction | 18487452
|
C081489 |
valsartan |
valsartan inhibits the reaction [AGT protein results in increased ubiquitination of SYP protein] | decreases reaction|increases ubiquitination | 18487452
|
C047426 |
venlafaxine |
venlafaxine results in increased expression of SYP mRNA | increases expression | 17950272
|
Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
---|
MESH:D000014 |
Abnormalities, Drug-Induced |
|
Tetrachlorodibenzodioxin |
7.49 | 15322242 14514962 11752688 |
MESH:D000014 |
Abnormalities, Drug-Induced |
|
Valproic Acid |
7.49 | 8875741 |
MESH:D000015 |
Abnormalities, Multiple |
|
Valproic Acid |
3.71 | 19490988 |
MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
3.31 | 18287403 |
MESH:D000168 |
Acrocephalosyndactylia |
|
U 0126 |
5.23 | 17694057 |
MESH:D055371 |
Acute Lung Injury |
|
Chlorine |
4.10 | 20601635 |
MESH:D000230 |
Adenocarcinoma |
|
Methylnitrosourea |
3.06 | 15113128 15688392 |
MESH:D000236 |
Adenoma |
|
Ethylnitrosourea |
3.58 | 6695378 |
MESH:D018248 |
Adenoma, Liver Cell |
|
Tetrachlorodibenzodioxin |
3.13 | 16835633 |
MESH:D000505 |
Alopecia |
|
Tretinoin |
3.42 | 15955085 |
MESH:D000544 |
Alzheimer Disease |
|
Ozone |
2.39 | 15513908 |
MESH:D000550 |
Amblyopia |
|
Valproic Acid |
4.98 | 17688650 |
MESH:D000690 |
Amyotrophic Lateral Sclerosis |
|
4-hydroxy-2-nonenal |
3.95 | 10965797 |
MESH:D000740 |
Anemia |
|
Tetrachlorodibenzodioxin |
2.73 | 11748828 |
MESH:D001008 |
Anxiety Disorders |
|
Fluoxetine |
8.69 | 18083778 |
MESH:D001008 |
Anxiety Disorders |
|
Valproic Acid |
8.69 | 17497229 |
MESH:D001169 |
Arthritis, Experimental |
|
Dexamethasone |
7.03 | 17659584 |
MESH:D001169 |
Arthritis, Experimental |
|
Tretinoin |
7.03 | 16412693 |
MESH:D001172 |
Arthritis, Rheumatoid |
|
Ozone |
4.46 | 15570426 |
MESH:D001172 |
Arthritis, Rheumatoid |
|
Tretinoin |
4.46 | 16292516 |
MESH:D001249 |
Asthma |
|
Ozone |
4.69 | 16373670 17854713 |
MESH:D001249 |
Asthma |
|
Tretinoin |
4.69 | 16456186 |
MESH:D001321 |
Autistic Disorder |
|
Fluoxetine |
2.57 | 19232924 18775368 |
MESH:D001321 |
Autistic Disorder |
|
Valproic Acid |
2.57 | 18985861 18940202 17507914 20603192 18558336 18177632 17688650 19232924 18316065 19460635 17157402 18775368 15238991 16609825 18396377 |
MESH:D001471 |
Barrett Esophagus |
|
Tretinoin |
4.17 | 16935849 |
MESH:D001714 |
Bipolar Disorder |
|
Valproic Acid |
2.95 | 20046352 17594078 |
MESH:D001778 |
Blood Coagulation Disorders |
|
Tetrachlorodibenzodioxin |
8.21 | 12125929 |
MESH:D001778 |
Blood Coagulation Disorders |
|
Tretinoin |
8.21 | 16206674 16197459 |
MESH:D001836 |
Body Weight Changes |
|
Tetrachlorodibenzodioxin |
3.54 | 15340226 |
MESH:D001848 |
Bone Diseases, Developmental |
|
Tetrachlorodibenzodioxin |
7.50 | 15746008 |
MESH:D001848 |
Bone Diseases, Developmental |
|
Valproic Acid |
7.50 | 8888407 |
MESH:D001927 |
Brain Diseases |
|
Ethylnitrosourea |
4.67 | 14991843 |
MESH:D001932 |
Brain Neoplasms |
|
Ethylnitrosourea |
4.08 | 15144691 16436596 16651633 18412241 16357521 |
MESH:D001943 |
Breast Neoplasms |
|
Acrylamide |
2.01 | 16253758 18183576 |
MESH:D001943 |
Breast Neoplasms |
|
Methylnitrosourea |
2.01 | 14633655 16253758 11306469 |
MESH:D001943 |
Breast Neoplasms |
|
Tetrachlorodibenzodioxin |
2.01 | 20435547 |
MESH:D001943 |
Breast Neoplasms |
|
Tretinoin |
2.01 | 16443354 16873071 16166294 |
MESH:D016535 |
Bronchial Hyperreactivity |
|
Ozone |
3.49 | 15516495 17626835 19059883 16777450 14754758 18417511 18315731 |
MESH:D001997 |
Bronchopulmonary Dysplasia |
|
Tretinoin |
4.34 | 16813970 |
MESH:D002100 |
Cachexia |
|
Ozone |
4.49 | 16183385 |
MESH:D002276 |
Carcinoid Tumor |
|
Streptozocin |
5.35 | 16051944 |
MESH:D002277 |
Carcinoma |
|
Tetrachlorodibenzodioxin |
2.61 | 16835633 |
MESH:D018236 |
Carcinoma, Embryonal |
|
Tretinoin |
4.91 | 16168501 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
Tretinoin |
1.86 | 1917145 |
MESH:D002294 |
Carcinoma, Squamous Cell |
|
Tretinoin |
2.22 | 16096774 16051514 |
MESH:D006332 |
Cardiomegaly |
|
Tetrachlorodibenzodioxin |
6.67 | 16120746 18670907 18850075 |
MESH:D006332 |
Cardiomegaly |
|
valsartan |
6.67 | 19597038 |
MESH:D009202 |
Cardiomyopathies |
|
valsartan |
4.28 | 16247790 |
MESH:D002318 |
Cardiovascular Diseases |
|
abacavir |
11.65 | 18753925 |
MESH:D002318 |
Cardiovascular Diseases |
|
Hydrogen Peroxide |
11.65 | 16936243 |
MESH:D002318 |
Cardiovascular Diseases |
|
valsartan |
11.65 | 11230374 |
MESH:D002386 |
Cataract |
|
Methylnitrosourea |
7.27 | 12484553 |
MESH:D002386 |
Cataract |
|
Tretinoin |
7.27 | 17460283 |
MESH:D002418 |
Cattle Diseases |
|
Acrylamide |
5.20 | 12510666 |
MESH:D002471 |
Cell Transformation, Neoplastic |
|
Ethylnitrosourea |
6.84 | 16003739 |
MESH:D002471 |
Cell Transformation, Neoplastic |
|
Methylnitrosourea |
6.84 | 7505956 2727394 |
MESH:D016543 |
Central Nervous System Neoplasms |
|
Ethylnitrosourea |
5.73 | 17160924 |
MESH:D018290 |
Cervical Intraepithelial Neoplasia |
|
Tretinoin |
4.34 | 16129372 |
MESH:D002659 |
Child Development Disorders, Pervasive |
|
Valproic Acid |
2.62 | 20734317 |
MESH:D018281 |
Cholangiocarcinoma |
|
Tetrachlorodibenzodioxin |
2.96 | 16835633 |
MESH:D002822 |
Choriocarcinoma |
|
Tretinoin |
4.91 | 16461808 |
MESH:D002972 |
Cleft Palate |
|
Tetrachlorodibenzodioxin |
5.42 | 12621046 8697196 15340226 15668235 16354765 |
MESH:D002972 |
Cleft Palate |
|
Tretinoin |
5.42 | 9407595 |
MESH:D003092 |
Colitis |
|
Tretinoin |
3.46 | 17035595 |
MESH:D003110 |
Colonic Neoplasms |
|
Dexamethasone |
2.45 | 15824018 |
MESH:D000013 |
Congenital Abnormalities |
|
Tetrachlorodibenzodioxin |
2.85 | 14669216 17141729 |
MESH:D003324 |
Coronary Artery Disease |
|
valsartan |
3.81 | 17719468 |
MESH:D003384 |
Coxsackievirus Infections |
|
valsartan |
5.60 | 20392896 |
MESH:D019465 |
Craniofacial Abnormalities |
|
Dexamethasone |
5.18 | 17728286 |
MESH:D019465 |
Craniofacial Abnormalities |
|
Tetrachlorodibenzodioxin |
5.18 | 10048152 20055451 15322242 |
MESH:D019465 |
Craniofacial Abnormalities |
|
Tretinoin |
5.18 | 9142499 8800419 9211117 14991402 9224671 10589399 17551590 9125849 16925845 9664655 |
MESH:D019465 |
Craniofacial Abnormalities |
|
Valproic Acid |
5.18 | 16575769 8888407 17688650 |
MESH:D003866 |
Depressive Disorder |
|
Fluoxetine |
8.23 | 15014590 |
MESH:D003866 |
Depressive Disorder |
|
venlafaxine |
8.23 | 20305041 |
MESH:D017449 |
Dermatitis, Allergic Contact |
|
Dexamethasone |
3.18 | 12438553 |
MESH:D003920 |
Diabetes Mellitus |
|
Streptozocin |
4.52 | 16285004 |
MESH:D003921 |
Diabetes Mellitus, Experimental |
|
Streptozocin |
8.48 | 18715473 12093613 12446591 19960420 18603373 8740154 16286809 7637645 2177838 16684804 6379147 1374869 15862027 11055810 15298345 11260395 15831366 19496084 19586609 17874149 17442507 12083368 12644472 19298542 |
MESH:D003921 |
Diabetes Mellitus, Experimental |
|
valsartan |
8.48 | 11508273 |
MESH:D003922 |
Diabetes Mellitus, Type 1 |
|
Streptozocin |
3.56 | 18603373 |
MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
Streptozocin |
4.44 | 19586609 19647726 |
MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
Tetrachlorodibenzodioxin |
4.44 | 17107852 |
MESH:D058065 |
Diabetic Cardiomyopathies |
|
Streptozocin |
5.48 | 16025228 |
MESH:D003928 |
Diabetic Nephropathies |
|
Streptozocin |
9.10 | 19960420 19682444 |
MESH:D003928 |
Diabetic Nephropathies |
|
valsartan |
9.10 | 18630688 11427623 |
MESH:D003930 |
Diabetic Retinopathy |
|
Streptozocin |
5.19 | 17662242 |
MESH:D003967 |
Diarrhea |
|
Dexamethasone |
3.47 | 7237001 |
MESH:D004342 |
Drug Hypersensitivity |
|
abacavir |
5.20 | 15867870 15024131 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
Chlorodiphenyl (54% Chlorine) |
5.89 | 17851650 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
Tetrachlorodibenzodioxin |
5.89 | 20420201 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
Valproic Acid |
5.89 | 1733752 19641884 |
MESH:D004362 |
Drug Toxicity |
|
Tetrachlorodibenzodioxin |
2.58 | 11462148 |
MESH:D004417 |
Dyspnea |
|
Chlorine |
4.38 | 20016425 |
MESH:D004421 |
Dystonia |
|
Valproic Acid |
3.82 | 1851702 |
MESH:D004476 |
Ectodermal Dysplasia |
|
Ethylnitrosourea |
5.73 | 18357618 |
MESH:D004485 |
Eczema |
|
Dexamethasone |
4.22 | 12438553 |
MESH:D004487 |
Edema |
|
Dexamethasone |
10.43 | 19703484 |
MESH:D004487 |
Edema |
|
Fluoxetine |
10.43 | 12798668 |
MESH:D004487 |
Edema |
|
Tetrachlorodibenzodioxin |
10.43 | 11000095 12711302 |
MESH:D004489 |
Edema, Cardiac |
|
Tetrachlorodibenzodioxin |
11.11 | 18230668 15322242 16714409 |
MESH:D004489 |
Edema, Cardiac |
|
Tretinoin |
11.11 | 18230668 |
MESH:D016889 |
Endometrial Neoplasms |
|
Tretinoin |
2.95 | 16569247 |
MESH:D004715 |
Endometriosis |
|
Tetrachlorodibenzodioxin |
2.81 | 9294722 10568697 |
MESH:D004831 |
Epilepsies, Myoclonic |
|
Valproic Acid |
3.91 | 3659116 17275665 |
MESH:D004828 |
Epilepsies, Partial |
|
Valproic Acid |
3.67 | 16628512 3922381 |
MESH:D004827 |
Epilepsy |
|
Valproic Acid |
2.81 | 20417680 18234410 |
MESH:D004832 |
Epilepsy, Absence |
|
Valproic Acid |
3.38 | 6426943 7562514 6254150 |
MESH:D017029 |
Epilepsy, Complex Partial |
|
Valproic Acid |
4.06 | 7750514 |
MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Valproic Acid |
3.82 | 3659116 |
MESH:D005124 |
Eye Abnormalities |
|
Tetrachlorodibenzodioxin |
8.24 | 11564622 |
MESH:D005124 |
Eye Abnormalities |
|
Tretinoin |
8.24 | 9664655 16938888 |
MESH:D005234 |
Fatty Liver |
|
Valproic Acid |
3.09 | 14986274 19224547 |
MESH:D005313 |
Fetal Death |
|
Tetrachlorodibenzodioxin |
3.21 | 11858732 |
MESH:D005315 |
Fetal Diseases |
|
Valproic Acid |
4.64 | 16575769 |
MESH:D005317 |
Fetal Growth Retardation |
|
Valproic Acid |
3.90 | 18558336 8888407 |
MESH:D005354 |
Fibrosarcoma |
|
Methylnitrosourea |
4.98 | 11555667 |
MESH:D005355 |
Fibrosis |
|
Tetrachlorodibenzodioxin |
13.54 | 20067830 |
MESH:D005355 |
Fibrosis |
|
Tretinoin |
13.54 | 17994277 |
MESH:D005355 |
Fibrosis |
|
valsartan |
13.54 | 16893502 |
MESH:D005739 |
Gas Poisoning |
|
Chlorine |
4.76 | 20016425 |
MESH:D005909 |
Glioblastoma |
|
Ethylnitrosourea |
6.89 | 16436596 |
MESH:D005909 |
Glioblastoma |
|
Tretinoin |
6.89 | 17312396 |
MESH:D005910 |
Glioma |
|
Ethylnitrosourea |
6.28 | 16651633 16357521 18412241 |
MESH:D005910 |
Glioma |
|
Methylnitrosourea |
6.28 | 9825942 |
MESH:D015432 |
Glomerulonephritis, Membranoproliferative |
|
valsartan |
5.31 | 16928621 |
MESH:D006058 |
Gonadal Disorders |
|
Tetrachlorodibenzodioxin |
4.34 | 10696789 |
MESH:D006258 |
Head and Neck Neoplasms |
|
Tretinoin |
3.02 | 16096774 |
MESH:D006317 |
Hearing Loss, Noise-Induced |
|
Tretinoin |
4.91 | 16084493 |
MESH:D006330 |
Heart Defects, Congenital |
|
Tetrachlorodibenzodioxin |
6.11 | 10048152 11294989 |
MESH:D006330 |
Heart Defects, Congenital |
|
Tretinoin |
6.11 | 14991402 9664655 |
MESH:D006331 |
Heart Diseases |
|
Streptozocin |
4.11 | 12093613 |
MESH:D006333 |
Heart Failure |
|
valsartan |
4.10 | 19027736 |
MESH:D006470 |
Hemorrhage |
|
Tetrachlorodibenzodioxin |
3.12 | 11000095 |
MESH:D006529 |
Hepatomegaly |
|
Tetrachlorodibenzodioxin |
2.65 | 12621046 16120746 15340226 |
MESH:D006548 |
Hernia, Diaphragmatic |
|
Dexamethasone |
2.99 | 7520565 |
MESH:D015658 |
HIV Infections |
|
abacavir |
4.76 | 17457083 12891065 11141242 |
MESH:D019584 |
Hot Flashes |
|
Fluoxetine |
10.37 | 14716179 |
MESH:D019584 |
Hot Flashes |
|
venlafaxine |
10.37 | 14716179 |
MESH:D006849 |
Hydrocephalus |
|
Valproic Acid |
4.62 | 17688650 |
MESH:D006869 |
Hydronephrosis |
|
Tetrachlorodibenzodioxin |
3.80 | 15340226 8697196 16959395 18606429 16354765 |
MESH:D006930 |
Hyperalgesia |
|
Tretinoin |
3.02 | 16870215 |
MESH:D017681 |
Hypereosinophilic Syndrome |
|
Tretinoin |
4.33 | 16778211 |
MESH:D006973 |
Hypertension |
|
Dexamethasone |
11.76 | 17042910 |
MESH:D006973 |
Hypertension |
|
telmisartan |
11.76 | 16077267 |
MESH:D006973 |
Hypertension |
|
Tetrachlorodibenzodioxin |
11.76 | 18850075 18670907 |
MESH:D006973 |
Hypertension |
|
valsartan |
11.76 | 18344623 16475468 12692753 10903974 20102058 18390891 12850387 11427623 |
MESH:D006974 |
Hypertension, Malignant |
|
valsartan |
6.16 | 11560862 |
MESH:D046110 |
Hypertension, Pregnancy-Induced |
|
Hydralazine |
4.38 | 16612254 |
MESH:D007247 |
Infertility, Female |
|
Acrylamide |
4.98 | 11020651 |
MESH:D007248 |
Infertility, Male |
|
Acrylamide |
7.04 | 15749267 12507653 15355880 11020651 |
MESH:D007248 |
Infertility, Male |
|
Methylnitrosourea |
7.04 | 7193160 |
MESH:D007249 |
Inflammation |
|
Dexamethasone |
7.79 | 11099482 8960868 |
MESH:D007249 |
Inflammation |
|
Fluoxetine |
7.79 | 12798668 |
MESH:D007249 |
Inflammation |
|
Tetrachlorodibenzodioxin |
7.79 | 12878042 12200463 |
MESH:D007410 |
Intestinal Diseases |
|
Tretinoin |
3.53 | 17994277 |
MESH:D007569 |
Jaw Abnormalities |
|
Tetrachlorodibenzodioxin |
9.20 | 16580747 |
MESH:D007569 |
Jaw Abnormalities |
|
Tretinoin |
9.20 | 17551590 15992940 |
MESH:D007674 |
Kidney Diseases |
|
Streptozocin |
6.53 | 12093613 |
MESH:D007674 |
Kidney Diseases |
|
valsartan |
6.53 | 16893502 10903974 12164870 |
MESH:D007676 |
Kidney Failure, Chronic |
|
Hydrogen Peroxide |
4.05 | 16518626 |
MESH:D007680 |
Kidney Neoplasms |
|
Ethylnitrosourea |
3.74 | 17379185 |
MESH:D007938 |
Leukemia |
|
Tretinoin |
2.65 | 17143497 |
MESH:D007948 |
Leukemia, Monocytic, Acute |
|
PD 98059 |
11.27 | 16972261 |
MESH:D007948 |
Leukemia, Monocytic, Acute |
|
U 0126 |
11.27 | 16972261 |
MESH:D007951 |
Leukemia, Myeloid |
|
Tretinoin |
3.48 | 16482212 16932348 19285840 |
MESH:D015470 |
Leukemia, Myeloid, Acute |
|
Tretinoin |
3.73 | 16294345 19850784 17596541 |
MESH:D015470 |
Leukemia, Myeloid, Acute |
|
Valproic Acid |
3.73 | 17596541 16294345 |
MESH:D015473 |
Leukemia, Promyelocytic, Acute |
|
Tretinoin |
2.99 | 17339181 19029980 16140955 19075265 17649720 19225113 9834237 17294898 17107899 12679006 19642359 16766008 17712046 15748426 16891316 16331271 19035177 17368321 17301526 17361223 16935935 16788101 16823087 17217047 17506722 |
MESH:D017880 |
Limb Deformities, Congenital |
|
Methylnitrosourea |
7.88 | 15526292 |
MESH:D017880 |
Limb Deformities, Congenital |
|
Tretinoin |
7.88 | 9224671 |
MESH:D008064 |
Lipidoses |
|
Fluoxetine |
4.48 | 15342952 17567588 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Dexamethasone |
4.77 | 16718785 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Tetrachlorodibenzodioxin |
4.77 | 12878042 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Tretinoin |
4.77 | 18397230 16248980 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
valsartan |
4.77 | 15619341 16872305 15504291 |
MESH:D017114 |
Liver Failure, Acute |
|
venlafaxine |
5.19 | 19857765 |
MESH:D008113 |
Liver Neoplasms |
|
Tetrachlorodibenzodioxin |
1.63 | 16984957 |
MESH:D008114 |
Liver Neoplasms, Experimental |
|
styrene oxide |
5.97 | 12562636 |
MESH:D008114 |
Liver Neoplasms, Experimental |
|
Tetrachlorodibenzodioxin |
5.97 | 12151625 |
MESH:D038061 |
Lower Extremity Deformities, Congenital |
|
Methylnitrosourea |
5.22 | 16080182 |
MESH:D008171 |
Lung Diseases |
|
Ozone |
3.21 | 8266340 19066396 |
MESH:D017563 |
Lung Diseases, Interstitial |
|
Valproic Acid |
4.01 | 17228818 |
MESH:D055370 |
Lung Injury |
|
Ozone |
3.61 | 20417186 |
MESH:D008175 |
Lung Neoplasms |
|
Dexamethasone |
6.29 | 15824018 11195469 |
MESH:D008175 |
Lung Neoplasms |
|
Ethylnitrosourea |
6.29 | 6695378 16019985 16271038 17703301 |
MESH:D008175 |
Lung Neoplasms |
|
Methylnitrosourea |
6.29 | 18062963 |
MESH:D008175 |
Lung Neoplasms |
|
Ozone |
6.29 | 8597069 7614698 |
MESH:D008175 |
Lung Neoplasms |
|
Tetrachlorodibenzodioxin |
6.29 | 11884234 19555203 |
MESH:D008223 |
Lymphoma |
|
Ethylnitrosourea |
7.54 | 15790496 |
MESH:D008223 |
Lymphoma |
|
Methylnitrosourea |
7.54 | 16257854 11418001 |
MESH:D016393 |
Lymphoma, B-Cell |
|
Methylnitrosourea |
4.54 | 14633661 |
MESH:D016399 |
Lymphoma, T-Cell |
|
Ethylnitrosourea |
4.81 | 15375218 |
MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Ethylnitrosourea |
9.49 | 10838139 18041768 10767621 |
MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Methylnitrosourea |
9.49 | 14999141 12931682 16619500 10838139 11751437 17131329 15113128 16051031 16944150 17020996 15688392 16827153 15313902 19196723 11807958 14633655 10767621 |
MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Tocopherols |
9.49 | 17927505 |
MESH:D008527 |
Medulloblastoma |
|
Tretinoin |
2.69 | 17453147 |
MESH:D008545 |
Melanoma |
|
Tretinoin |
1.91 | 16752155 |
MESH:D008579 |
Meningioma |
|
Ethylnitrosourea |
5.73 | 17943659 |
MESH:D008591 |
Meningomyelocele |
|
Tretinoin |
4.18 | 16940565 |
MESH:D001523 |
Mental Disorders |
|
Fluoxetine |
8.11 | 16856516 |
MESH:D001523 |
Mental Disorders |
|
venlafaxine |
8.11 | 16856516 |
MESH:D038901 |
Mental Retardation, X-Linked |
marker/mechanism |
|
| 19377476 |
OMIM:300802 |
MENTAL RETARDATION, X-LINKED, SYP-RELATED |
marker/mechanism |
|
| |
MESH:D008654 |
Mesothelioma |
|
Tocopherols |
4.01 | 15878867 |
MESH:D008679 |
Metaplasia |
|
Ozone |
4.86 | 10496685 |
MESH:D008881 |
Migraine Disorders |
|
Valproic Acid |
7.55 | 18803445 18765137 |
MESH:D008881 |
Migraine Disorders |
|
venlafaxine |
7.55 | 18803445 |
MESH:D009101 |
Multiple Myeloma |
|
Dexamethasone |
3.33 | 15744524 16118317 15867202 |
MESH:D009139 |
Musculoskeletal Abnormalities |
|
Valproic Acid |
3.81 | 8888407 |
MESH:D009190 |
Myelodysplastic Syndromes |
|
Dexamethasone |
11.56 | 9809623 |
MESH:D009190 |
Myelodysplastic Syndromes |
|
Tretinoin |
11.56 | 17596541 |
MESH:D009190 |
Myelodysplastic Syndromes |
|
Valproic Acid |
11.56 | 17596541 |
MESH:D009203 |
Myocardial Infarction |
|
abacavir |
4.58 | 18753925 |
MESH:D017202 |
Myocardial Ischemia |
|
Tetrachlorodibenzodioxin |
2.83 | 12213967 |
MESH:D009207 |
Myoclonus |
|
Fluoxetine |
5.63 | 8041377 |
MESH:D009369 |
Neoplasms |
|
Methylnitrosourea |
5.01 | 15533788 |
MESH:D009369 |
Neoplasms |
|
Tretinoin |
5.01 | 16594593 16946489 |
MESH:D009374 |
Neoplasms, Experimental |
|
Ethylnitrosourea |
8.87 | 16707424 |
MESH:D009374 |
Neoplasms, Experimental |
|
Methylnitrosourea |
8.87 | 12696579 |
MESH:D009410 |
Nerve Degeneration |
|
Acrylamide |
4.51 | 12387366 12387367 11264303 |
MESH:D009422 |
Nervous System Diseases |
|
Acrylamide |
4.78 | 12507653 12164553 |
MESH:D009421 |
Nervous System Malformations |
|
Tetrachlorodibenzodioxin |
8.73 | 14600291 |
MESH:D009421 |
Nervous System Malformations |
|
Tretinoin |
8.73 | 9125849 |
MESH:D009436 |
Neural Tube Defects |
|
Tretinoin |
6.78 | 9142499 |
MESH:D009436 |
Neural Tube Defects |
|
Valproic Acid |
6.78 | 8888407 16359493 |
MESH:D009442 |
Neurilemmoma |
|
Ethylnitrosourea |
12.46 | 16003739 16651423 17160924 |
MESH:D009442 |
Neurilemmoma |
|
Methylnitrosourea |
12.46 | 11555667 |
MESH:D009771 |
Obsessive-Compulsive Disorder |
|
Fluoxetine |
10.93 | 20418887 |
MESH:D009771 |
Obsessive-Compulsive Disorder |
|
venlafaxine |
10.93 | 17503984 |
MESH:D009837 |
Oligodendroglioma |
|
Ethylnitrosourea |
5.73 | 17160924 |
MESH:D010051 |
Ovarian Neoplasms |
|
Tretinoin |
4.98 | 16936753 |
MESH:D010051 |
Ovarian Neoplasms |
|
U 0126 |
4.98 | 16211241 |
MESH:D010146 |
Pain |
|
Fluoxetine |
6.65 | 12798668 |
MESH:D010146 |
Pain |
|
Tretinoin |
6.65 | 16870215 |
MESH:D010190 |
Pancreatic Neoplasms |
|
Methylnitrosourea |
5.30 | 16965848 |
MESH:D010190 |
Pancreatic Neoplasms |
|
Tretinoin |
5.30 | 15976015 |
MESH:D010212 |
Papilloma |
|
Hydrogen Peroxide |
3.85 | 12065085 |
MESH:D010382 |
Peliosis Hepatis |
|
Tetrachlorodibenzodioxin |
4.00 | 12520081 |
MESH:D010523 |
Peripheral Nervous System Diseases |
|
Acrylamide |
4.87 | 11510240 |
MESH:D010538 |
Peritonitis |
|
Ozone |
3.89 | 16369182 |
MESH:D010787 |
Photosensitivity Disorders |
|
4-hydroxy-2-nonenal |
5.25 | 11550810 |
MESH:D020774 |
Pick Disease of the Brain |
|
Fluoxetine |
5.76 | 8041377 |
MESH:D011014 |
Pneumonia |
|
Ozone |
4.15 | 18007984 18381685 18929643 |
MESH:D017119 |
Porphyria Cutanea Tarda |
|
Tetrachlorodibenzodioxin |
3.32 | 18163543 |
MESH:D054198 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma |
|
Dexamethasone |
3.41 | 21297632 |
MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Tetrachlorodibenzodioxin |
8.64 | 11118676 11399792 11896295 11222880 |
MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Valproic Acid |
8.64 | 20603192 |
MESH:D011471 |
Prostatic Neoplasms |
|
Methylnitrosourea |
4.17 | 12376480 15682402 |
MESH:D011471 |
Prostatic Neoplasms |
|
Tocopherols |
4.17 | 12504091 |
MESH:D011507 |
Proteinuria |
|
telmisartan |
14.50 | 16077267 |
MESH:D011507 |
Proteinuria |
|
Tretinoin |
14.50 | 16636307 |
MESH:D011507 |
Proteinuria |
|
valsartan |
14.50 | 17664856 18344623 12164870 |
MESH:D019310 |
Pseudolymphoma |
|
Valproic Acid |
4.29 | 11422049 12752131 |
MESH:D011625 |
Pterygium |
|
Tretinoin |
4.55 | 16723453 |
MESH:D011658 |
Pulmonary Fibrosis |
|
valsartan |
3.72 | 17241526 |
MESH:D012120 |
Respiration Disorders |
|
Chlorine |
4.96 | 18579056 |
MESH:D012128 |
Respiratory Distress Syndrome, Adult |
|
Dexamethasone |
3.79 | 11700416 18379247 |
MESH:D015619 |
Respiratory System Abnormalities |
|
Tetrachlorodibenzodioxin |
3.60 | 18990726 |
MESH:D012162 |
Retinal Degeneration |
|
Methylnitrosourea |
4.23 | 18172121 18155124 |
MESH:D012175 |
Retinoblastoma |
|
Methylnitrosourea |
5.24 | 11555667 |
MESH:D012208 |
Rhabdomyosarcoma |
|
Tretinoin |
10.10 | 16116481 16283617 |
MESH:D012208 |
Rhabdomyosarcoma |
|
Valproic Acid |
10.10 | 19155313 |
MESH:D012559 |
Schizophrenia |
marker/mechanism |
|
| 11483314 |
MESH:D012559 |
Schizophrenia |
|
Valproic Acid |
2.04 | 15737665 19110320 |
MESH:D012640 |
Seizures |
|
Valproic Acid |
2.58 | 16876388 15475178 17978042 11044598 3137016 1511512 11738929 14763951 |
MESH:D020230 |
Serotonin Syndrome |
|
Fluoxetine |
5.65 | 8704074 |
MESH:D012878 |
Skin Neoplasms |
|
Hydrogen Peroxide |
8.81 | 12065085 |
MESH:D012878 |
Skin Neoplasms |
|
Tetrachlorodibenzodioxin |
8.81 | 16192470 |
MESH:D012878 |
Skin Neoplasms |
|
Tretinoin |
8.81 | 16467112 |
MESH:D016135 |
Spinal Dysraphism |
|
Valproic Acid |
3.59 | 19490988 |
MESH:D013226 |
Status Epilepticus |
|
Valproic Acid |
4.29 | 12833885 |
MESH:D013272 |
Stomach Diseases |
|
Dexamethasone |
4.08 | 15472012 |
MESH:D013274 |
Stomach Neoplasms |
|
Methylnitrosourea |
3.60 | 16257854 15930296 18593901 |
MESH:D013274 |
Stomach Neoplasms |
|
styrene oxide |
3.60 | 12562636 |
MESH:D013274 |
Stomach Neoplasms |
|
Tretinoin |
3.60 | 17261132 |
MESH:D013276 |
Stomach Ulcer |
|
Dexamethasone |
3.27 | 15138204 |
MESH:D013733 |
Testicular Diseases |
|
Acrylamide |
4.98 | 15864552 |
MESH:D013953 |
Thymus Neoplasms |
|
Ethylnitrosourea |
11.48 | 15790496 |
MESH:D013953 |
Thymus Neoplasms |
|
Methylnitrosourea |
11.48 | 11418001 |
MESH:D013959 |
Thyroid Diseases |
|
Tetrachlorodibenzodioxin |
3.65 | 12697716 |
MESH:D013964 |
Thyroid Neoplasms |
|
Methylnitrosourea |
6.90 | 7505956 3078959 |
MESH:D013964 |
Thyroid Neoplasms |
|
Tretinoin |
6.90 | 16026305 17045167 |
MESH:D014062 |
Tongue Neoplasms |
|
Tretinoin |
3.57 | 16051514 |
MESH:D014178 |
Translocation, Genetic |
|
Valproic Acid |
4.98 | 17262798 |
MESH:D014376 |
Tuberculosis |
|
Tretinoin |
3.08 | 16040207 |
MESH:D020194 |
Unverricht-Lundborg Syndrome |
|
Valproic Acid |
4.27 | 3119515 |
MESH:D014564 |
Urogenital Abnormalities |
|
Valproic Acid |
4.40 | 8888407 |
MESH:D002583 |
Uterine Cervical Neoplasms |
|
Tretinoin |
3.46 | 16129372 |
MESH:D014604 |
Uveal Neoplasms |
|
Tretinoin |
4.36 | 16752155 |
MESH:D014605 |
Uveitis |
|
Dexamethasone |
4.57 | 1336536 |
MESH:D054079 |
Vascular Malformations |
|
Tetrachlorodibenzodioxin |
4.34 | 12125929 |
MESH:D020257 |
Ventricular Remodeling |
|
valsartan |
5.45 | 19027736 |
MESH:D014820 |
Vitiligo |
|
Tretinoin |
3.82 | 16761959 |
MESH:D019282 |
Wasting Syndrome |
|
Tetrachlorodibenzodioxin |
4.00 | 15886252 |
MESH:D009396 |
Wilms Tumor |
|
Tretinoin |
3.76 | 16287080 |