AutismKB 2.0

Annotation Detail for TACR1


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Basic Information Top
Gene Symbol:TACR1 ( NK1R,NKIR,SPR,TAC1R )
Gene Full Name: tachykinin receptor 1
Band: 2p12
Quick LinksEntrez ID:6869; OMIM: 162323; Uniprot ID:NK1R_HUMAN; ENSEMBL ID: ENSG00000115353; HGNC ID: 11526
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04080Neuroactive ligand-receptor interaction
hsa04020Calcium signaling pathway
Pathway IDPathway Name
Signaling by GPCR
No data
No data
Pathway IDPathway Name
500407Tachykinin receptors bind tachykinins
Related Diseases/Disorders Top
No data
No data
Desease Name
slow transit constipation
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C080755 3-(2-methoxybenzylamino)-2-phenylpiperidine 3-(2-methoxybenzylamino)-2-phenylpiperidine inhibits the reaction [TAC1 protein results in increased expression of TACR1 mRNA]decreases reaction|increases expression 18441096
C080755 3-(2-methoxybenzylamino)-2-phenylpiperidine 3-(2-methoxybenzylamino)-2-phenylpiperidine binds to and results in decreased activity of TACR1 proteinaffects binding|decreases activity 18441096
D000643 Ammonium Chloride Ammonium Chloride affects the expression of TACR1 mRNAaffects expression 16483693
D003913 Dextroamphetamine TACR1 protein affects the susceptibility to Dextroamphetamineaffects response to substance 11897087
C114556 aprepitant aprepitant inhibits the reaction [TAC1 protein results in increased expression of TACR1 mRNA]decreases reaction|increases expression 18441096
C114556 aprepitant aprepitant binds to and results in decreased activity of TACR1 proteinaffects binding|decreases activity 18441096
C015001 arsenite [arsenite co-treated with Benzo(a)pyrene] results in decreased expression of TACR1 mRNAaffects cotreatment|decreases expression 15894712
C015001 arsenite arsenite results in decreased expression of TACR1 mRNAdecreases expression 15894712
D001564 Benzo(a)pyrene [arsenite co-treated with Benzo(a)pyrene] results in decreased expression of TACR1 mRNAaffects cotreatment|decreases expression 15894712
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of TACR1 mRNAdecreases expression 15894712
D002211 Capsaicin Capsaicin results in decreased expression of TACR1 mRNAdecreases expression 18441096
D002211 Capsaicin Capsaicin results in decreased expression of TACR1 proteindecreases expression 18441096
D004051 Diethylhexyl Phthalate Diethylhexyl Phthalate results in increased expression of TACR1 mRNAincreases expression 15620428
D004394 Dydrogesterone Dydrogesterone results in decreased expression of TACR1 proteindecreases expression 16389545
D019833 Genistein Genistein inhibits the reaction [CALCA protein results in increased expression of TACR1 mRNA]decreases reaction|increases expression 16777450
D019833 Genistein Genistein inhibits the reaction [CALCA protein results in increased expression of TACR1 protein]decreases reaction|increases expression 16777450
D006851 Hydrochloric Acid TACR1 affects the susceptibility to Hydrochloric Acidaffects response to substance 12212954
D006851 Hydrochloric Acid TACR1 protein affects the susceptibility to Hydrochloric Acidaffects response to substance 11730984
C076851 L 703606 L 703606 binds to and results in decreased activity of TACR1 proteinaffects binding|decreases activity 18364471
D008345 Manganese Manganese results in decreased expression of TACR1 mRNAdecreases expression 17175027
C025340 manganese chloride manganese chloride results in decreased expression of TACR1 mRNAdecreases expression 17175027
C063509 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CALCA protein results in increased expression of TACR1 mRNA]decreases reaction|increases expression 16777450
C063509 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CALCA protein results in increased expression of TACR1 protein]decreases reaction|increases expression 16777450
C502587 (N-N'-bis-(2-(1H-indol-3-yl)-ethyl)-N,N'-bis-(3-thiomorpholin-4-yl-propyl)-phthalamide) (N-N'-bis-(2-(1H-indol-3-yl)-ethyl)-N,N'-bis-(3-thiomorpholin-4-yl-propyl)-phthalamide) binds to TACR1 proteinaffects binding 15925360
D010100 Oxygen TACR1 protein results in increased susceptibility to Oxygenincreases response to substance 11463606
D010126 Ozone Ozone results in increased expression of TACR1 mRNAincreases expression 16777450
C025299 polyphenols polyphenols results in decreased expression of TACR1 mRNAdecreases expression 16293270
C071693 RP 67580 RP 67580 binds to and results in decreased activity of TACR1 proteinaffects binding|decreases activity 17056641
C071693 RP 67580 RP 67580 binds to and results in decreased activity of TACR1 proteinaffects binding|decreases activity 18364471
C071693 RP 67580 RP 67580 results in decreased activity of TACR1 proteindecreases activity 17056641
C054724 senktide senktide binds to and results in increased activity of TACR1 proteinaffects binding|increases activity 11245602
C017947 sodium arsenite sodium arsenite results in increased activity of TACR1 proteinincreases activity 17056641
C085215 SR 140333 SR 140333 binds to and results in decreased activity of TACR1 proteinaffects binding|decreases activity 9219603
11245602
9179376
C085215 SR 140333 SR 140333 binds to and results in decreased activity of TACR1 proteinaffects binding|decreases activity 14585802
C526005 SR140333B SR140333B binds to and results in decreased activity of TACR1 proteinaffects binding|decreases activity 16788306
C105686 SU 5402 SU 5402 inhibits the reaction [FGF2 protein results in increased expression of TACR1 mRNA alternative form]decreases reaction|increases expression 16154193
C105686 SU 5402 SU 5402 inhibits the reaction [TNF protein results in increased expression of TACR1 mRNA alternative form]decreases reaction|increases expression 16154193
C105686 SU 5402 SU 5402 results in decreased expression of TACR1 mRNA alternative formdecreases expression 16154193
D013654 Taurine Taurine results in decreased expression of TACR1 mRNAdecreases expression 16579726
D014635 Valproic Acid Valproic Acid results in decreased expression of TACR1 mRNAdecreases expression 12807426
C017967 W 7 W 7 inhibits the reaction [CALCA protein results in increased expression of TACR1 mRNA]decreases reaction|increases expression 16777450
C017967 W 7 W 7 inhibits the reaction [CALCA protein results in increased expression of TACR1 protein]decreases reaction|increases expression 16777450
D015054 Zymosan Zymosan affects the localization of TACR1 proteinaffects localization 17257769
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Capsaicin 13.0518926900
MESH:D000014 Abnormalities, Drug-Induced Diethylhexyl Phthalate 13.056734493
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 13.058875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.6919490988
MESH:D000033 Abortion, Threatened Dydrogesterone 6.8915760377
MESH:D000138 Acidosis Ammonium Chloride 9.8518287403
MESH:D000138 Acidosis Hydrochloric Acid 9.8516144966 19262391 15920416 20872349 12771618 11574821
MESH:D000141 Acidosis, Renal Tubular Hydrochloric Acid 5.5117183249
MESH:D000142 Acidosis, Respiratory Hydrochloric Acid 5.5520597076
MESH:D058186 Acute Kidney Injury Capsaicin 4.3118460982
MESH:D055371 Acute Lung Injury Hydrochloric Acid 9.0319060228 15970105 11850527 11953099 19094174 16759491 19760209
MESH:D055371 Acute Lung Injury Oxygen 9.0316759491
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.1920127859 20464547
MESH:D000230 Adenocarcinoma Genistein 4.1911473722
MESH:D000236 Adenoma Benzo(a)pyrene 2.506695378
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.4315276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.6417306315 16712894
MESH:D000437 Alcoholism marker/mechanism 19204064
MESH:D000505 Alopecia Capsaicin 4.5217569567
MESH:D000544 Alzheimer Disease Ozone 2.3815513908
MESH:D000550 Amblyopia Valproic Acid 4.9717688650
MESH:D000740 Anemia Zymosan 4.3318664788
MESH:D000756 Anemia, Sideroblastic Manganese 10.2516910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 10.2516910769
MESH:D000860 Anoxia Hydrochloric Acid 10.7415090967
MESH:D000860 Anoxia Oxygen 10.7420872349
MESH:D001008 Anxiety Disorders Valproic Acid 3.3717497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.8219183758
MESH:D001169 Arthritis, Experimental Zymosan 3.9616872482 17659584 15944321 15142272 15188379
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5015570426
MESH:D001249 Asthma Ozone 2.5616373670 17854713
MESH:D050197 Atherosclerosis Oxygen 3.6516391483
MESH:D001289 Attention Deficit Disorder with Hyperactivity marker/mechanism 19204064
MESH:D001321 Autistic Disorder Valproic Acid 2.0318985861 17688650 20603192 16609825 18558336 18775368 15238991 17507914 18940202 19232924 17157402 19460635 18177632 18396377 18316065
MESH:D001714 Bipolar Disorder marker/mechanism 19204064
MESH:D001714 Bipolar Disorder Valproic Acid 2.9420046352 17594078
MESH:D001778 Blood Coagulation Disorders Hydrochloric Acid 4.5815920416
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.248888407
MESH:D001919 Bradycardia Capsaicin 4.7918207255
MESH:D002545 Brain Ischemia Capsaicin 4.7119211983
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0520146248 17474063
MESH:D001943 Breast Neoplasms Genistein 2.0516873071 16541309 17200150
MESH:D001943 Breast Neoplasms Oxygen 2.0517263869
MESH:D016535 Bronchial Hyperreactivity Hydrochloric Acid 8.2512378975
MESH:D016535 Bronchial Hyperreactivity Ozone 8.2515516495 17626835 18315731 16777450 19059883 14754758 18417511
MESH:D001986 Bronchial Spasm Hydrochloric Acid 5.2015578804
MESH:D002100 Cachexia Ozone 4.4816183385
MESH:D006528 Carcinoma, Hepatocellular Genistein 3.0516924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 3.0515276417 17306315 16507464
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.3420419170
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.3418572023
MESH:D002318 Cardiovascular Diseases Genistein 3.1316332659
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 2.8119524636 20056578
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6120734317
MESH:D003110 Colonic Neoplasms arsenite 5.6715037631
MESH:D003110 Colonic Neoplasms Genistein 5.6717182828
MESH:D003110 Colonic Neoplasms polyphenols 5.6716293270
MESH:D003371 Cough Capsaicin 4.9110350223
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.888888407 17688650 16575769
MESH:D003556 Cystitis Hydrochloric Acid 5.2019279288 20719367 12853844 12599022
MESH:D018856 Cystitis, Interstitial Hydrochloric Acid 5.5517714534
MESH:D003876 Dermatitis, Atopic Diethylhexyl Phthalate 3.9316882537
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 2.4216647724
MESH:D058065 Diabetic Cardiomyopathies Taurine 5.7916025228
MESH:D003967 Diarrhea SR 140333 5.639219603
MESH:D056486 Drug-Induced Liver Injury polyphenols 6.1019370779
MESH:D056486 Drug-Induced Liver Injury Taurine 6.109328219
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 6.1019641884 1733752
MESH:D004381 Duodenal Ulcer Capsaicin 4.4410671773 11535926
MESH:D004417 Dyspnea Oxygen 4.5720016425
MESH:D004421 Dystonia Valproic Acid 3.811851702
MESH:D004487 Edema Zymosan 3.767907874
MESH:D004714 Endometrial Hyperplasia Genistein 4.3316402032
MESH:D016889 Endometrial Neoplasms Genistein 3.1911473722
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.903659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 3.6516628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.8020417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.377562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.047750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.803659116
MESH:D004935 Esophageal Diseases Capsaicin 12.6219566590
MESH:D004935 Esophageal Diseases Hydrochloric Acid 12.6219566590
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 1.9416530937
MESH:D004941 Esophagitis Hydrochloric Acid 5.7312928072
MESH:D004942 Esophagitis, Peptic Hydrochloric Acid 5.7520516732 14621274 11346197
MESH:D005234 Fatty Liver arsenite 7.3218296743
MESH:D005234 Fatty Liver Valproic Acid 7.3219224547 14986274
MESH:D005315 Fetal Diseases Valproic Acid 4.6216575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.888888407 18558336
MESH:D005355 Fibrosis arsenite 8.6218296743
MESH:D005355 Fibrosis Hydrochloric Acid 8.6218497604
MESH:D005739 Gas Poisoning Hydrochloric Acid 11.3112378975
MESH:D005739 Gas Poisoning Oxygen 11.3120016425
MESH:D005764 Gastroesophageal Reflux Hydrochloric Acid 5.0819957777 19951613 20516732 12212954 20616304 20545468
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.4216452187
MESH:D005909 Glioblastoma Capsaicin 11.1818405923
MESH:D005909 Glioblastoma Genistein 11.1816598420
MESH:D005909 Glioblastoma Manganese 11.1817043766
MESH:D006356 Heartburn Capsaicin 12.6219566590
MESH:D006356 Heartburn Hydrochloric Acid 12.6219566590
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.5220471113
MESH:D006505 Hepatitis Zymosan 4.4519110552
MESH:D006689 Hodgkin Disease sodium arsenite 2.9412676792
MESH:D006849 Hydrocephalus Valproic Acid 4.6017688650
MESH:D006930 Hyperalgesia Capsaicin 4.1217043245 17434803
MESH:D006940 Hyperemia Hydrochloric Acid 5.3912646421
MESH:D006975 Hypertension, Portal Hydrochloric Acid 5.0916984587
MESH:D006976 Hypertension, Pulmonary Hydrochloric Acid 4.2719262391
MESH:D007022 Hypotension Hydrochloric Acid 4.5211574821
MESH:D007248 Infertility, Male sodium arsenite 2.8212646999 15346721
MESH:D007249 Inflammation Capsaicin 11.0416956363
MESH:D007249 Inflammation Hydrochloric Acid 11.0411574821
MESH:D007249 Inflammation polyphenols 11.0416366677
MESH:D007249 Inflammation Zymosan 11.048014878 11289658
MESH:D007410 Intestinal Diseases Hydrochloric Acid 4.7111574821
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.5717553498
MESH:D007674 Kidney Diseases sodium arsenite 2.6520008137
MESH:D007818 Laryngeal Diseases Hydrochloric Acid 6.0916498863
MESH:D007826 Laryngismus Hydrochloric Acid 6.0911510729
MESH:D007938 Leukemia Genistein 2.8918980019 17468513
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1117596541 16294345
MESH:D008103 Liver Cirrhosis arsenite 6.8118296743
MESH:D008103 Liver Cirrhosis Hydrochloric Acid 6.8116984587
MESH:D008106 Liver Cirrhosis, Experimental Genistein 3.0617823541
MESH:D008106 Liver Cirrhosis, Experimental Taurine 3.0615931870 15893842
MESH:D008107 Liver Diseases Capsaicin 4.5216956363
MESH:D008107 Liver Diseases polyphenols 4.5216698588
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 7.0320195826 21137059
MESH:D008113 Liver Neoplasms Diethylhexyl Phthalate 7.0311940454
MESH:D008113 Liver Neoplasms sodium arsenite 7.0315276417 16712894
MESH:D008171 Lung Diseases Hydrochloric Acid 11.5116784557
MESH:D008171 Lung Diseases Ozone 11.5119066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 11.5119095001
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.0017228818
MESH:D055370 Lung Injury Hydrochloric Acid 13.9219262391 16129981 18497604 20597076 21311175 15090967 11395602 18573544 18339021 17627322 15607125 15044056 19644408 21114838
MESH:D055370 Lung Injury Oxygen 13.9218339021
MESH:D055370 Lung Injury Ozone 13.9220417186
MESH:D008175 Lung Neoplasms arsenite 4.6216809336
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.626695378 20464547 20135361 18520028 18816296 17053015 18569708 20869020 20064080
MESH:D008175 Lung Neoplasms Ozone 4.627614698 8597069
MESH:D008175 Lung Neoplasms sodium arsenite 4.6217306315 15276417 17077188 19931552 16712894
MESH:D008325 Mammary Neoplasms, Experimental Genistein 2.7814578162 12929590
MESH:D020149 Manganese Poisoning Manganese 5.2519453300 16551646 16568477
MESH:D008545 Melanoma sodium arsenite 2.0016487513 19082730
MESH:D008679 Metaplasia Ozone 4.8410496685
MESH:D008881 Migraine Disorders Valproic Acid 3.0118803445 18765137
MESH:D009041 Motion Sickness Dextroamphetamine 5.251613127
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.9916381670
MESH:D009069 Movement Disorders Manganese 4.7716551646
MESH:D009101 Multiple Myeloma Capsaicin 3.9717505005
MESH:D009102 Multiple Organ Failure Zymosan 4.9612879239 12130978 10890648 18160304 15241586 17724436 15259001 15213630 15834315 10479408
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.798888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.0117596541
MESH:D009203 Myocardial Infarction Genistein 5.9217141266
MESH:D009203 Myocardial Infarction Hydrochloric Acid 5.9218534312
MESH:D015428 Myocardial Reperfusion Injury Genistein 3.4617141266
MESH:D009369 Neoplasms Benzo(a)pyrene 4.5911141357
MESH:D009369 Neoplasms sodium arsenite 4.5911559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.4120056578
MESH:D009389 Neovascularization, Pathologic arsenite 4.1515738583
MESH:D009410 Nerve Degeneration Manganese 4.0816551646
MESH:D009421 Nervous System Malformations Genistein 3.7816427766
MESH:D009436 Neural Tube Defects sodium arsenite 6.7712854658
MESH:D009436 Neural Tube Defects Valproic Acid 6.7716359493 8888407
MESH:D020078 Neurogenic Inflammation marker/mechanism 17257769
MESH:D020078 Neurogenic Inflammation Capsaicin 4.8517961222
MESH:D009765 Obesity Capsaicin 3.3319056576
MESH:D009784 Occupational Diseases Hydrochloric Acid 4.5412378975
MESH:D010024 Osteoporosis Genistein 3.0919401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.8416169203
MESH:D010051 Ovarian Neoplasms Genistein 4.6919005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 4.6917306315 15276417
MESH:D010146 Pain Capsaicin 3.8118987195 17434803 19081190 16996476 17084039 17043245
MESH:D010300 Parkinson Disease Manganese 3.2811181820
MESH:D020734 Parkinsonian Disorders Manganese 4.2416140633
MESH:D010538 Peritonitis Ozone 9.5516369182
MESH:D010538 Peritonitis Zymosan 9.5514761945 15259001 17826846 17371808 18977430 19088179 11985352 18557954 15979727 18760300 19641140
MESH:D011014 Pneumonia Ozone 4.1318381685 18007984 18929643
MESH:D011015 Pneumonia, Aspiration Hydrochloric Acid 5.1118573544 15970105 18497604 15607125
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 3.5720603192
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.6517292933
MESH:D011471 Prostatic Neoplasms Genistein 2.6516925846 15378649 15256057
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.6516039940
MESH:D019310 Pseudolymphoma Valproic Acid 4.2711422049 12752131
MESH:D001261 Pulmonary Atelectasis Hydrochloric Acid 5.7520597076
MESH:D011654 Pulmonary Edema Hydrochloric Acid 4.9515090967
MESH:D015427 Reperfusion Injury Capsaicin 3.8318460982 19211983
MESH:D012128 Respiratory Distress Syndrome, Adult Hydrochloric Acid 8.9518339021 18549715 16129981 16784557 17627322
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 8.9518339021 17627322
MESH:D012133 Respiratory Paralysis Hydrochloric Acid 6.0911510729
MESH:D012140 Respiratory Tract Diseases Hydrochloric Acid 4.9020516732
MESH:D012208 Rhabdomyosarcoma Valproic Acid 3.9319155313
MESH:D012559 Schizophrenia Valproic Acid 2.0319110320 15737665
MESH:D012640 Seizures Valproic Acid 2.571511512 3137016 17978042 11044598 11738929 14763951 16876388 15475178
MESH:D018805 Sepsis Zymosan 4.4411441115
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.3010029692 19755658
MESH:D012878 Skin Neoplasms sodium arsenite 5.3018572023 19524636
MESH:D016135 Spinal Dysraphism sodium arsenite 8.8812854658
MESH:D016135 Spinal Dysraphism Valproic Acid 8.8819490988
MESH:D013226 Status Epilepticus Valproic Acid 4.2712833885
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5520155912 2093021
MESH:D013276 Stomach Ulcer Hydrochloric Acid 4.0016755016 17189318 15309881
MESH:D013398 Sudden Infant Death Oxygen 5.2812563064
MESH:D013705 Temporomandibular Joint Disorders Capsaicin 12.4717997062
MESH:D013705 Temporomandibular Joint Disorders polyphenols 12.4717997062
MESH:D014178 Translocation, Genetic Valproic Acid 4.9717262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.263119515
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 4.7017053015
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 4.7016712894 11723127 17306315 16452187
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.388888407
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.5411813266
MESH:D014605 Uveitis Zymosan 5.1311006244
MESH:D014652 Vascular Diseases sodium arsenite 4.1617056641
Pathway ID Pathway Name
KEGG:04020 Calcium signaling pathway
KEGG:05162 Measles
KEGG:04080 Neuroactive ligand-receptor interaction
REACT:14797 Signaling by GPCR
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36302
    • No data
    Releated disease ID Related disease Name
    PA443309Alcoholism
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00673 antagonist Aprepitant Antiemetics
    DB01221 antagonist Ketamine Analgesics;General Anesthetics;Excitatory Amino Acid Antagonists;Anesthetics, Dissociative
    DB04894 antagonist Vapreotide Antineoplastic Agents;Analgesics
    DB06717 antagonist Fosaprepitant Antiemetics
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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