AutismKB 2.0

Annotation Detail for TALDO1


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Basic Information Top
Gene Symbol:TALDO1 ( TAL,TAL-H,TALDOR,TALH )
Gene Full Name: transaldolase 1
Band: 11p15.5
Quick LinksEntrez ID:6888; OMIM: 602063; Uniprot ID:TALDO_HUMAN; ENSEMBL ID: ENSG00000177156; HGNC ID: 11559
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PENTOSE-P-PWYpentose phosphate pathway
NONOXIPENT-PWYpentose phosphate pathway (non-oxidative branch)
Pathway IDPathway Name
hsa00030Pentose phosphate pathway
hsa01100Metabolic pathways
Pathway IDPathway Name
Metabolism of carbohydrates
Integration of energy metabolism
No data
Pathway IDPathway Name
P02762Pentose phosphate pathway
Pathway IDPathway Name
500683Pentose phosphate pathway (hexose monophosphate shunt)
500718Insulin effects increased synthesis of Xylulose-5-Phosphate
Related Diseases/Disorders Top
No data
No data
No data
No data
Desease Name
Transaldolase deficiency
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016392 3,3'-diindolylmethane 3,3'-diindolylmethane results in decreased expression of TALDO1 mRNAdecreases expression 16192472
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of TALDO1 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen results in increased expression of TALDO1 mRNAincreases expression 15084756
D000643 Ammonium Chloride Ammonium Chloride affects the expression of TALDO1 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of TALDO1 mRNAincreases expression 20458559
D019324 beta-Naphthoflavone beta-Naphthoflavone results in increased expression of TALDO1 mRNAincreases expression 19737606
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of TALDO1 mRNAaffects expression 17484886
D003474 Curcumin Curcumin results in increased expression of TALDO1 mRNAincreases expression 18299980
D016572 Cyclosporine Cyclosporine results in increased expression of TALDO1 mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of TALDO1 mRNAdecreases expression 18042831
D004052 Diethylnitrosamine [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TALDO1 mRNAaffects cotreatment|increases expression 16158176
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TALDO1 mRNAaffects cotreatment|increases expression 14656948
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of TALDO1 mRNAincreases expression 19638242
D004958 Estradiol Estradiol results in decreased expression of TALDO1 mRNAdecreases expression 16192472
D015073 2-Acetylaminofluorene [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TALDO1 mRNAaffects cotreatment|increases expression 16158176
D015073 2-Acetylaminofluorene [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TALDO1 mRNAaffects cotreatment|increases expression 14656948
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of TALDO1 mRNAaffects cotreatment|increases expression 17183730
C004925 methylmercuric chloride methylmercuric chloride results in increased expression of TALDO1 mRNAincreases expression 17961207
D015741 Metribolone Metribolone results in decreased expression of TALDO1 proteindecreases expression 17152098
C041786 palm oil palm oil results in decreased expression of TALDO1 mRNAdecreases expression 18042831
D016226 Phosphorus, Dietary Phosphorus, Dietary affects the expression of TALDO1 mRNAaffects expression 17651324
C006253 pirinixic acid pirinixic acid results in increased expression of TALDO1 mRNAincreases expression 20059764
18301758
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of TALDO1 mRNA]increases expression|increases reaction 20059764
D012643 Selenium Selenium results in increased expression of TALDO1 mRNAincreases expression 19244175
C009277 sodium arsenate sodium arsenate results in increased expression of TALDO1 mRNAincreases expression 16882884
D014501 Uranium Uranium affects the expression of TALDO1 mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of TALDO1 mRNAaffects expression 15672453
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of TALDO1 mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced methylmercuric chloride 8.436734493
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 8.438875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.7719490988
MESH:D000138 Acidosis Ammonium Chloride 3.3918287403
MESH:D055371 Acute Lung Injury pirinixic acid 2.9618653653
MESH:D000230 Adenocarcinoma arsenic trioxide 4.2519825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 4.2511473722
MESH:D000236 Adenoma 2-Acetylaminofluorene 15.2310737359
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 15.233712494
MESH:D000236 Adenoma beta-Naphthoflavone 15.2319389873
MESH:D000236 Adenoma Diethylnitrosamine 15.2310737359 6695378
MESH:D002759 Adenoma, Bile Duct 2-Acetylaminofluorene 5.846705139
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.5219052882 17162532 16434500 18056438 19061943 17620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.5216434500
MESH:D019973 Alcohol-Related Disorders Curcumin 4.9117887948
MESH:D000544 Alzheimer Disease Curcumin 2.5815590663
MESH:D000550 Amblyopia Valproic Acid 5.0617688650
MESH:D000799 Angioedema Acetaminophen 3.6710982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.4417497229
MESH:D001161 Arteriosclerosis Dietary Fats 3.7215238619
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.7016807698
MESH:D050197 Atherosclerosis Curcumin 3.2218704882
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8517688650 19232924 18985861 18177632 17507914 18775368 18558336 20603192 15238991 18396377 18316065 19460635 18940202 16609825 17157402
MESH:D001327 Autoimmune Diseases Curcumin 4.3219761891
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.851440618 11289319
MESH:D001714 Bipolar Disorder Valproic Acid 2.9920046352 17594078
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.4816206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.4819483382
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.298888407
MESH:D002545 Brain Ischemia Curcumin 4.1616770732
MESH:D001932 Brain Neoplasms Curcumin 3.7917596214
MESH:D001943 Breast Neoplasms Curcumin 1.9518462866 18593918 19250217 16243823
MESH:D001943 Breast Neoplasms Dietary Fats 1.9520435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9517474063
MESH:D001943 Breast Neoplasms Estradiol 1.9517289903 19861407 14630087 16675129 17261762 17018787 18497071 12948864
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1711589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.2916111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.6116050911 15700767 10355542 16124888 3786805 15721981 16192424 15673190 16097048 16011737 16227642 18705752
MESH:D002277 Carcinoma Curcumin 3.7018593918
MESH:D006528 Carcinoma, Hepatocellular 2-Acetylaminofluorene 13.6610737359 17761372 3581430 3084413 6705139
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 13.667296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 13.663084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 13.6615073043 16217749 15553829 11135700 14691202
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 13.6618788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 13.6616288022 16569478 17428255 16328049 19701751 16878318 20007298 16502159 18506893 16935385 19418558 18788625 16807293 19052882 18785209 20727157 19335982 20512989 16779866 10672840 18393292 16540662 18978308 17162532 3581430 19383236 19171122 19208518 19539802 17055752 17761372 20514400 19822196 20101231 17138121 20214788 3084413 16830150 11831363 19919837 18056438 19107877 18691550 16698587 16681979 18210153 19394651 18494052 20524982 21159647 18971187 10737359 19519916 20432363 20084675 20935162 17173139 17978847 18665156
MESH:D006528 Carcinoma, Hepatocellular Estradiol 13.6616924424
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.9218414057
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7019014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.607296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9712490120
MESH:D002294 Carcinoma, Squamous Cell Curcumin 2.7118462866
MESH:D002386 Cataract Acetaminophen 2.4810977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 15.047505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.0412371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 15.0417174075 7505956 2727394 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 15.0418566989
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6520734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.5419052882
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 12.6519486331 9022650
MESH:D002779 Cholestasis Cyclosporine 12.6519486331
MESH:D002779 Cholestasis pirinixic acid 12.6519176532
MESH:D003092 Colitis Curcumin 9.1018200517 16804969 16782535
MESH:D003092 Colitis Selenium 9.1017936198
MESH:D003103 Coloboma Curcumin 4.3918809619
MESH:D003110 Colonic Neoplasms Curcumin 2.4819359593 16340194
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D016510 Corneal Neovascularization Curcumin 4.7318497527
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.8610525206
MESH:D019465 Craniofacial Abnormalities sodium arsenate 3.8610525206
MESH:D019465 Craniofacial Abnormalities Valproic Acid 3.8616575769 8888407 17688650
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9315213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.648970840 12868966 11298694 14531868 18759878 11906362 8156756 2524372
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3518249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.333621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 4.4618403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.4620387270
MESH:D003928 Diabetic Nephropathies Curcumin 8.5518204486
MESH:D003928 Diabetic Nephropathies Estradiol 8.5519279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 17.9018289764 1440618 11289319 18648102 6482804 8291058 9022650 7440962 9653073 18692083 9328219 16192314 6679447
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 17.9014550746 11834606 10663392 14986274 11743745 12392966 10774834 19420014 18713872 12594235 12153990 17522070 12540782 16781746 18071297 19370779 12705907 14725611 11739529 17562736 17906064 16109766 11529661 10915739 11461765 19923254 2444490 16485898 11287661 19739265 16227642 15968718 19085960 16393943 16177239 19416960 16081117 15619225 11421492 12958197 19164858
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 17.907120509 9327722 16177239 10915739 6623471 21278145 11566570 2869522 19085960 7179309 3786805 6884620 3732212 10092053 7440962 17522070 15998439 16227642 19336974 4309450 15968718 15027814
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 17.9019107877
MESH:D056486 Drug-Induced Liver Injury Selenium 17.9015131321
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 17.9018186108
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 17.9019641884 1733752
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9319426721
MESH:D004381 Duodenal Ulcer Curcumin 3.8817351913
MESH:D050171 Dyslipidemias Dietary Fats 3.3318367378
MESH:D004421 Dystonia Valproic Acid 3.891851702
MESH:D004487 Edema pirinixic acid 2.3312083418
MESH:D016889 Endometrial Neoplasms Estradiol 2.8718566989 11473722 19148513
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.983659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 3.7516628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.8518234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.447562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.137750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.893659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9416302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.323581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.3212903497
MESH:D005234 Fatty Liver arsenic trioxide 40.6815073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 40.6861145 16239168 12795759 17595544 16045604 12631006 19224547 15959796
MESH:D005234 Fatty Liver Curcumin 40.6819297423
MESH:D005234 Fatty Liver Cyclosporine 40.6819224547
MESH:D005234 Fatty Liver Dietary Fats 40.6819551842 19004024 17967931 18296743
MESH:D005234 Fatty Liver Diethylnitrosamine 40.6821071580 20387270
MESH:D005234 Fatty Liver pirinixic acid 40.6820131406 19236843
MESH:D005234 Fatty Liver Valproic Acid 40.6814986274 19224547
MESH:D005315 Fetal Diseases Valproic Acid 4.7116575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.9618558336 8888407
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.856705139
MESH:D005355 Fibrosis Carbon Tetrachloride 19.7818705752
MESH:D005355 Fibrosis Curcumin 19.7818705752
MESH:D005355 Fibrosis Cyclosporine 19.7812168785 12639820
MESH:D005355 Fibrosis Dietary Fats 19.7818296743
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1016904648
MESH:D005756 Gastritis Acetaminophen 3.5016983495
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.5218462866
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.058708960
MESH:D005909 Glioblastoma Curcumin 3.3717596214
MESH:D018149 Glucose Intolerance sodium arsenate 4.9219446573
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.887505956
MESH:D006258 Head and Neck Neoplasms Curcumin 3.5418829502 18462866
MESH:D006333 Heart Failure pirinixic acid 6.6020558911
MESH:D006333 Heart Failure Selenium 6.6017162251
MESH:D006390 Hemangioendothelioma 2-Acetylaminofluorene 5.146705139
MESH:D006394 Hemangiosarcoma 2-Acetylaminofluorene 4.256705139
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2515720958
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.676705139
MESH:D006505 Hepatitis Carbon Tetrachloride 8.6719900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 2.8319772884 18467677 19176532 16221962
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.8717701891
MESH:D006558 Herpes Genitalis Estradiol 4.8615709030
MESH:D019584 Hot Flashes Estradiol 3.5817088409
MESH:D006849 Hydrocephalus Valproic Acid 4.6917688650
MESH:D006930 Hyperalgesia Acetaminophen 2.5716870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3616899240
MESH:D006937 Hypercholesterolemia Curcumin 8.7118704882
MESH:D006937 Hypercholesterolemia Dietary Fats 8.7121332399
MESH:D006943 Hyperglycemia pirinixic acid 3.0320558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.4521332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.7715034207
MESH:D006973 Hypertension Cyclosporine 2.0410903974
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9215338365
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.4516612254
MESH:D007249 Inflammation Curcumin 7.9017151092 16956363 18403477
MESH:D007249 Inflammation Dietary Fats 7.9020412841
MESH:D007249 Inflammation Diethylnitrosamine 7.9018785209
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.1418596194 18200517
MESH:D007251 Influenza, Human Selenium 4.0216624496
MESH:D007333 Insulin Resistance Dietary Fats 11.6511836018 18457598
MESH:D007333 Insulin Resistance Estradiol 11.6516627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 11.6516306350
MESH:D007414 Intestinal Neoplasms Curcumin 4.0710783313
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.858074119 9022650
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2715604871
MESH:D007674 Kidney Diseases Acetaminophen 9.4112587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 9.4118776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 9.4115618244
MESH:D007676 Kidney Failure, Chronic Selenium 3.7316518626
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.556582329
MESH:D007680 Kidney Neoplasms Cyclosporine 11.5512371664
MESH:D007680 Kidney Neoplasms Estradiol 11.5515610895
MESH:D007889 Leiomyoma Curcumin 4.4118555241
MESH:D007938 Leukemia arsenic trioxide 6.2315070760
MESH:D007938 Leukemia Curcumin 6.2318462866
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 9.2412560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 9.2416106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1316972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3014633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.6019077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.8017050201 19850784 20471514 16968895 16467208
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 3.8017596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.1019225113 12018890 16966277 17712046 17869043 15336539 11161223 12712474 15748426 16112521 12679006 16891316 16331271 16330433 16823087 9834237 15622746 15213294 17217047 19075265 19035177 17107899 11468182 17649720 19642359
MESH:D015458 Leukemia, T-Cell arsenic trioxide 11.1616882451
MESH:D015458 Leukemia, T-Cell Curcumin 11.1616106398
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.4716221502 11903743 17334410 16943688 17174718 11408273 16239168 21278145 17157831
MESH:D008103 Liver Cirrhosis Dietary Fats 10.4718296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.4720032147 18522880 18665156 18407596 19638242
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.0915034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.7918279442 14716496 18395914 16116963 16027843 17766677 16248980 15057751 18339082 17823541 18251166 16638106 12546737 15931870 15673190 15123356 18429990 13678700 15996030 14748882 17805973 18166357 18376398 18481824 18205269 14620537 12586293 18395095 17714472 12667390 18054572 15959796 18210741 17565644 12632514 12445418 12898905 12445421 15338365 16015684 18412020 18263696 15818738 16033810 17708605 12666154 15730626 17944888 10355542 17976157 12741479 17525996 17761835 17631135 17557913 12632512 17721639 16192424 15052691 18006644 18156304 15876570 12609069 12958196 12389079 15370692 17698563 18420326 15925388 14724832 18277467 15893842 18472332 18705752 15650968 16011737 16136751 17869086 17481882 18472094 20821823 18317297 18187930 14716833 16097048 17900296 12649538 17922224 11481614 15362042 18418968 17640975 14512876
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 4.7918006644 18705752 17355460
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.7914659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.7915474484
MESH:D008107 Liver Diseases Acetaminophen 9.0116610002 12969438 11587558 19014921 12587719 16611625 19784758 19460945
MESH:D008107 Liver Diseases Carbon Tetrachloride 9.0116246199 17285989 15830285 15720792 16964402
MESH:D008107 Liver Diseases Curcumin 9.0116956363
MESH:D008107 Liver Diseases Diethylnitrosamine 9.0117034775
MESH:D017093 Liver Failure Carbon Tetrachloride 3.9915123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.9116871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.9116899240 14706259
MESH:D008113 Liver Neoplasms 2-Acetylaminofluorene 17.1516273603 11376686 14678523 18001218 10672840 10737359
MESH:D008113 Liver Neoplasms arsenic trioxide 17.1514682389
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 17.1521295105 19389873
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 17.1519294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.159163691 20101389 20492335 19996281 21167192 15175105 19426721 20434301 16942905 19294768 21071580 18648771 19638242 20583210 19642983 18754104 20501860 19850985 19551842 15885732 21047994 19255062 2862719 18977376 12112319 19254457 19073162 19499222 12771043 20452335 19090486 21278145 19690152 2422723 19427195 19256749 10737359 20405173 19812893 20137499 18978307 19833225 20118626 18644402
MESH:D008113 Liver Neoplasms pirinixic acid 17.1520007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental 2-Acetylaminofluorene 22.00534488 6150874 1399818
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 22.001399818 6587162 3712494 598648
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 22.0020377131
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 22.0018164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 22.0015583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 22.0019539802 19126423 21159647 18253720 18282651 17174075 16267830 3124819 17854601 18308698 19009564 17942915 16842330 9362446 18775883 18164116 2563599 19004024 18093689 18544905 18079962 19519916
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2215213294
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.0917228818
MESH:D008175 Lung Neoplasms 2-Acetylaminofluorene 4.7611376686
MESH:D008175 Lung Neoplasms arsenic trioxide 4.7611798837 19825857
MESH:D008175 Lung Neoplasms Curcumin 4.7619359593 18462866 16243823
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.766695378 20970405 20512841 21163286
MESH:D008223 Lymphoma Curcumin 3.4718462866
MESH:D016399 Lymphoma, T-Cell Curcumin 4.5216173963
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.6611807958 16891317 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Selenium 5.6615318939
MESH:D020149 Manganese Poisoning Estradiol 4.3119453300
MESH:D008545 Melanoma Curcumin 2.3917885582 18462866
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4019513568
MESH:D008569 Memory Disorders Curcumin 3.9917263510
MESH:D008654 Mesothelioma Selenium 2.7215107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6216801185
MESH:D008881 Migraine Disorders Valproic Acid 3.0718765137 18803445
MESH:D009101 Multiple Myeloma arsenic trioxide 7.0415949261 19549372 14977855 19417148 11468182
MESH:D009101 Multiple Myeloma Curcumin 7.0419372569
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.7517962980
MESH:D009135 Muscular Diseases pirinixic acid 3.3416239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 10.1618186108
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 10.168888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.1016105982 16882451
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 7.1017596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.0719151258
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.8116810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.8116411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 9.7716624393
MESH:D009361 Neoplasm Invasiveness Curcumin 9.7718495463
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.473581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.473581430 9029167
MESH:D009369 Neoplasms pirinixic acid 1.8717405874
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 4.3612497104
MESH:D009389 Neovascularization, Pathologic Estradiol 3.5617289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1419348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 3.4911399458 16427766
MESH:D009423 Nervous System Neoplasms Curcumin 5.4618462866
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 16.466679447
MESH:D009436 Neural Tube Defects arsenic trioxide 16.4610525206
MESH:D009436 Neural Tube Defects sodium arsenate 16.4619446573 18186108 11749123 10525206
MESH:D009436 Neural Tube Defects Valproic Acid 16.4616359493 8888407
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.7118514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.7120387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9420387270
MESH:D009765 Obesity Curcumin 7.1819297423
MESH:D009765 Obesity Dietary Fats 7.1818457598 20132043 18674790 11836018 20518802 17217161 21332399 19632207 16723640
MESH:D009765 Obesity pirinixic acid 7.1820558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.276482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.853988306
MESH:D010024 Osteoporosis Curcumin 3.3718719352
MESH:D010051 Ovarian Neoplasms arsenic trioxide 7.6219769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms Curcumin 7.6218462866 19020741
MESH:D010051 Ovarian Neoplasms Estradiol 7.6219401270
MESH:D010146 Pain Acetaminophen 2.2516870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.3215580305
MESH:D010190 Pancreatic Neoplasms Curcumin 8.3219401701 17440100 19196508
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.3216540662
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.317296757
MESH:D010235 Paraganglioma arsenic trioxide 4.0019927285
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.306228378
MESH:D010954 Plasmacytoma Selenium 4.7215087411
MESH:D011230 Precancerous Conditions Cyclosporine 8.4612371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.462563599
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 3.6620603192
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.7320887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.6719131511
MESH:D011471 Prostatic Neoplasms Curcumin 2.6710851300 18226269 12497104 18156803 15129424 11398177 18769126
MESH:D011471 Prostatic Neoplasms Estradiol 2.6716740699
MESH:D019310 Pseudolymphoma Valproic Acid 4.3712752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.1716882103
MESH:D011656 Pulmonary Emphysema Curcumin 4.3819168576
MESH:D015427 Reperfusion Injury pirinixic acid 2.3019058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.8718379247 10666014
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.253692021
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.0119155313
MESH:D012509 Sarcoma Curcumin 3.9718462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.7916646077
MESH:D012559 Schizophrenia Valproic Acid 2.0519110320 15737665
MESH:D012640 Seizures Valproic Acid 2.6311044598 15475178 3137016 17978042 1511512 11738929 16876388 14763951
MESH:D018805 Sepsis Curcumin 3.9318389075
MESH:D016135 Spinal Dysraphism Valproic Acid 3.6519490988
MESH:D013226 Status Epilepticus Valproic Acid 4.3712833885
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4017007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.4018456281
MESH:D013276 Stomach Ulcer Curcumin 3.3516631530 19188055
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 11.203712494 1399818 6587162 6582329 7505956
MESH:D013964 Thyroid Neoplasms arsenic trioxide 11.2019014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.207505956
MESH:D013978 Tibial Fractures Estradiol 4.5119048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.7915213294
OMIM:606003 TRANSALDOLASE DEFICIENCY marker/mechanism
MESH:D014178 Translocation, Genetic Valproic Acid 5.0617262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.353119515
MESH:D001749 Urinary Bladder Neoplasms 2-Acetylaminofluorene 11.4415867355 15289314 1399818
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 11.448074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 11.4412973940 20435036 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Curcumin 11.4418593936
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.478888407
MESH:D014565 Urogenital Neoplasms Curcumin 5.0918462866
MESH:D014581 Urticaria Acetaminophen 2.8210982225
MESH:D014605 Uveitis Cyclosporine 3.811336536
MESH:D015430 Weight Gain Dietary Fats 3.5916723640
MESH:D014985 Xerophthalmia Cyclosporine 4.2717120751
Pathway ID Pathway Name
REACT:1505 Integration of energy metabolism
KEGG:01100 Metabolic pathways
REACT:474 Metabolism of carbohydrates
KEGG:00030 Pentose phosphate pathway
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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