AutismKB 2.0

Annotation Detail for TECTB


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Basic Information Top
Gene Symbol:TECTB ( KIAA1560,MGC142057,MGC142059 )
Gene Full Name: tectorin beta
Band: 10q25.2
Quick LinksEntrez ID:6975; OMIM: 602653; Uniprot ID:TECTB_HUMAN; ENSEMBL ID: ENSG00000119913; HGNC ID: 11721
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of TECTB mRNAdecreases expression 18648102
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of TECTB mRNAaffects binding|increases activity|increases expression 19710929
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.7218653653
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 3.003712494
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.3716434500
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 6.0911289319 1440618
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.7019483382
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 1.783581430 7296757
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.867296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 3.087505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 9.0719486331 9022650
MESH:D002779 Cholestasis pirinixic acid 9.0719176532
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.5518759878 8156756 14531868 2524372 11298694 12868966 8970840 11906362
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.6118249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 4.102952479 3621924
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 2.0611289319 16192314 9022650 1440618 18648102 6679447 6482804 9328219 18692083 7440962 9653073 18289764 8291058
MESH:D004487 Edema pirinixic acid 3.0212083418
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.193581430
MESH:D005234 Fatty Liver pirinixic acid 3.3120131406 19236843
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 6.096705139
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.647505956
MESH:D006333 Heart Failure pirinixic acid 2.8120558911
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 4.196705139
MESH:D006529 Hepatomegaly pirinixic acid 3.7619176532 19772884 16221962 18467677
MESH:D006943 Hyperglycemia pirinixic acid 3.6920558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.7015034207
MESH:D007333 Insulin Resistance pirinixic acid 2.9316306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 6.098074119 9022650
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.406582329
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.4715034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 1.9520007298 15890375 16377806
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.801399818 6587162 598648 3712494
MESH:D009135 Muscular Diseases pirinixic acid 4.2716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.3019151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.3316411023
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.623581430
MESH:D009369 Neoplasms pirinixic acid 2.1417405874
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.216679447
MESH:D009765 Obesity pirinixic acid 1.9020558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.926482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 6.093988306
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.247296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.546228378
MESH:D015427 Reperfusion Injury pirinixic acid 2.5819058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.743692021
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.261399818 6582329 6587162 7505956 3712494
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.428074119
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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