AutismKB 2.0

Annotation Detail for BUB1


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Basic Information Top
Gene Symbol:BUB1 ( BUB1A,BUB1L,hBUB1 )
Gene Full Name: budding uninhibited by benzimidazoles 1 homolog (yeast)
Band: 2q13
Quick LinksEntrez ID:699; OMIM: 602452; Uniprot ID:BUB1_HUMAN; ENSEMBL ID: ENSG00000169679; HGNC ID: 1148
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04914Progesterone-mediated oocyte maturation
hsa04110Cell cycle
hsa04114Oocyte meiosis
Pathway IDPathway Name
Cell Cycle, Mitotic
DNA Replication
Pathway IDPathway Name
200087PLK1 signaling events
200010Aurora B signaling
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
2164Barrett's esophagus
No data
No data
Desease Name
Colorectal cancer with chromosomal instability
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen results in decreased expression of BUB1 mRNAdecreases expression 17942131
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of BUB1 proteinaffects expression 20106945
D003913 Dextroamphetamine Dextroamphetamine results in increased expression of BUB1 mRNAincreases expression 12205029
D003913 Dextroamphetamine SOD1 inhibits the reaction [Dextroamphetamine results in increased expression of BUB1 mRNA]decreases reaction|increases expression 12205029
D001205 Ascorbic Acid [Quercetin co-treated with Ascorbic Acid] results in increased expression of BUB1 mRNAaffects cotreatment|increases expression 17639512
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of BUB1 mRNAdecreases expression 20106945
20064835
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of BUB1 mRNAdecreases expression 17942131
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of BUB1 mRNAdecreases expression 20018196
19150397
20382639
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in decreased expression of BUB1 mRNAdecreases expression 17942131
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of BUB1 mRNAincreases expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of BUB1 mRNAdecreases expression 20106945
D016572 Cyclosporine Cyclosporine results in decreased expression of BUB1 mRNAdecreases expression 17942131
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of BUB1 mRNAincreases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of BUB1 mRNA]decreases reaction|increases expression 17854601
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of BUB1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BUB1 mRNAaffects cotreatment|increases expression 17942748
D005472 Fluorouracil Fluorouracil results in decreased expression of BUB1 mRNAdecreases expression 16709241
C065180 fluvastatin [zoledronic acid co-treated with fluvastatin] results in increased expression of BUB1 mRNAaffects cotreatment|increases expression 16996129
D019833 Genistein Genistein affects the expression of BUB1 mRNAaffects expression 18847459
C051890 irinotecan irinotecan metabolite results in decreased expression of BUB1 mRNAdecreases expression 15956246
C051890 irinotecan irinotecan results in decreased expression of BUB1 mRNAdecreases expression 15956246
D008294 Malathion Malathion results in decreased expression of BUB1 mRNAdecreases expression 16079077
D008345 Manganese Manganese results in decreased expression of BUB1 mRNAdecreases expression 17175027
C025340 manganese chloride manganese chloride results in decreased expression of BUB1 mRNAdecreases expression 17175027
D008628 Mercury Mercury results in increased expression of BUB1 mRNAincreases expression 16823088
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of BUB1 mRNAincreases expression 20713471
D015741 Metribolone Metribolone results in increased expression of BUB1 mRNAincreases expression 19318562
D010126 Ozone TTPA protein affects the reaction [Ozone results in increased expression of BUB1 mRNA]affects reaction|increases expression 19555225
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of BUB1 mRNAincreases expression 17560707
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of BUB1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of BUB1 mRNAincreases expression 19482888
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of BUB1 mRNAaffects binding|decreases expression|increases activity 19710929
D011794 Quercetin [Quercetin co-treated with Ascorbic Acid] results in increased expression of BUB1 mRNAaffects cotreatment|increases expression 17639512
C059514 resveratrol resveratrol results in decreased expression of BUB1 mRNAdecreases expression 15767336
D013629 Tamoxifen Tamoxifen results in increased expression of BUB1 mRNAincreases expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BUB1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of BUB1 mRNAincreases expression 19465110
D014635 Valproic Acid Valproic Acid results in increased expression of BUB1 mRNAincreases expression 19101580
D014747 Vinblastine BUB1 protein affects the susceptibility to Vinblastineaffects response to substance 16217747
C088658 zoledronic acid [zoledronic acid co-treated with fluvastatin] results in increased expression of BUB1 mRNAaffects cotreatment|increases expression 16996129
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.2314745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 12.406195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 12.4015322242 11752688 14514962
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 12.408875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.6519490988
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6317505938
MESH:D058186 Acute Kidney Injury resveratrol 8.1516538975
MESH:D058186 Acute Kidney Injury zoledronic acid 8.1519715164
MESH:D055371 Acute Lung Injury pirinixic acid 2.8318653653
MESH:D000210 Acute-Phase Reaction zoledronic acid 5.1720200999
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 9.4720464547 20127859
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.4714692618
MESH:D000230 Adenocarcinoma Fluorouracil 9.4717638652
MESH:D000230 Adenocarcinoma Genistein 9.4711473722
MESH:D000236 Adenoma Benzo(a)pyrene 14.536695378
MESH:D000236 Adenoma Diethylnitrosamine 14.536695378 10737359
MESH:D000236 Adenoma Methylcholanthrene 14.5310545420 6695378
MESH:D000236 Adenoma resveratrol 14.5315688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 22.2917620307 18056438 17162532 19052882 19061943 16434500
MESH:D018248 Adenoma, Liver Cell Phenobarbital 22.2917620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 22.2916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 22.2916835633
MESH:D000382 Agricultural Workers' Diseases Malathion 4.6711874814 17119214
MESH:D000544 Alzheimer Disease Ozone 4.1315513908
MESH:D000544 Alzheimer Disease resveratrol 4.1316162502 16183991
MESH:D000550 Amblyopia Valproic Acid 4.9217688650
MESH:D000740 Anemia Fluorouracil 7.7916511603 17963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.7911748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.9617084956
MESH:D000756 Anemia, Sideroblastic Manganese 10.1116910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 10.1116910769
MESH:D000799 Angioedema Acetaminophen 3.5310982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.3317497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7719183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.7215885639
MESH:D001169 Arthritis, Experimental resveratrol 6.7217115116
MESH:D001172 Arthritis, Rheumatoid Ozone 2.4815570426
MESH:D001249 Asthma Ozone 2.5417854713 16373670
MESH:D001260 Ataxia Telangiectasia Quercetin 4.6715336622
MESH:D050197 Atherosclerosis Methylcholanthrene 6.3511922910
MESH:D050197 Atherosclerosis resveratrol 6.3516873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 2.1518445737
MESH:D001321 Autistic Disorder Mercury 2.1517497416
MESH:D001321 Autistic Disorder Valproic Acid 2.1518775368 17688650 16609825 17157402 19232924 18985861 18396377 18316065 18940202 18558336 19460635 17507914 15238991 20603192 18177632
MESH:D001327 Autoimmune Diseases Mercury 9.9916634805
MESH:D001327 Autoimmune Diseases Quercetin 9.9919761891
MESH:D001714 Bipolar Disorder Valproic Acid 2.9217594078 20046352
MESH:D001778 Blood Coagulation Disorders pirinixic acid 7.8519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.8512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.3615746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.368888407
MESH:D001859 Bone Neoplasms zoledronic acid 4.6719442620 17312309 16121404 15867366 11697798 16778634
MESH:D001862 Bone Resorption zoledronic acid 4.4315845617 8053405 11869084 16769263 18496637 18404659
MESH:D002545 Brain Ischemia resveratrol 3.9717600658
MESH:D001943 Breast Neoplasms Ascorbic Acid 9.2516443354
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 9.2517474063 20146248
MESH:D001943 Breast Neoplasms Diethylnitrosamine 9.2517474063
MESH:D001943 Breast Neoplasms Fluorouracil 9.2515136595 16110121 19217205 16557594 16595493 18608205 18357371
MESH:D001943 Breast Neoplasms Genistein 9.2516873071 17200150 16541309
MESH:D001943 Breast Neoplasms Malathion 9.2512762645
MESH:D001943 Breast Neoplasms Methylcholanthrene 9.2517474063
MESH:D001943 Breast Neoplasms Quercetin 9.2518628248
MESH:D001943 Breast Neoplasms resveratrol 9.2516393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tamoxifen 9.2520135344 18425577 19115204 19103187 17893378 18984771 11161223 20065188 20544844 18821012 16202921 18351453 18629630 20005174 15668708 18997820 15565566 19155303 19142967 19289846 18855134 19189210 16273361 19189212 16818667 17261762 20859285 21152245 19200415 19221464 19084267 19244106 18815881 20390343 19011961 17242785 17440819 19288272 19059307 19487384 16873071 17049068 21138602 19410462 19066611
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 9.2520435547
MESH:D001943 Breast Neoplasms zoledronic acid 9.2518695136 16096432
MESH:D016535 Bronchial Hyperreactivity Ozone 3.4416777450 17626835 18417511 19059883 18315731 14754758 15516495
MESH:D002100 Cachexia Ozone 4.4316183385
MESH:D002105 Cadmium Poisoning Quercetin 5.2316962696
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4816227642 16124888 16050911 16011737 15700767 16097048 15721981 15673190 18705752 10355542 3786805 16192424
MESH:D002276 Carcinoid Tumor Fluorouracil 4.3516051944
MESH:D002277 Carcinoma Fluorouracil 12.5817121937
MESH:D002277 Carcinoma Methylcholanthrene 12.5810545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 12.5816835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.2019066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 21.783084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 21.7821507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 21.7818788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 21.7819701751 19052882 18506893 21159647 16935385 17138121 16540662 19822196 17055752 16779866 20514400 3084413 18978308 3581430 16502159 19171122 16569478 19539802 20214788 18393292 20727157 19335982 17173139 18210153 16878318 17761372 19919837 17978847 10672840 16807293 18788625 18665156 16288022 19107877 19208518 19383236 16698587 20007298 16328049 20101231 20935162 17162532 18691550 16681979 18785209 16830150 18056438 20432363 18494052 11831363 20084675 19394651 18971187 19519916 17428255 20512989 19418558 20524982 10737359
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 21.7816799960 16332177 17971768 17045692 18930000 17088986
MESH:D006528 Carcinoma, Hepatocellular Genistein 21.7816924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 21.7817173139 20007298 20935162 6705139 1701930
MESH:D006528 Carcinoma, Hepatocellular Quercetin 21.7819519916 12508355
MESH:D006528 Carcinoma, Hepatocellular resveratrol 21.7819321006 16227395
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 21.7816924424
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.2816675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 3.4319233551
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.6517234771
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 10.1618695887
MESH:D002292 Carcinoma, Renal Cell Vinblastine 10.161485588
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 10.1618507039
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.0220419170
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 7.0217066447 16280240 18986760 16757204
MESH:D002294 Carcinoma, Squamous Cell resveratrol 7.0216227395
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3517572228
MESH:D006332 Cardiomegaly Quercetin 6.2319794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.2318670907 18850075 16120746
MESH:D002311 Cardiomyopathy, Dilated Mercury 3.3410334427
MESH:D002318 Cardiovascular Diseases Genistein 6.8016332659
MESH:D002318 Cardiovascular Diseases resveratrol 6.8015458977
MESH:D002386 Cataract Acetaminophen 2.4010977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 14.2920889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 14.2912371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 14.292727394 7505956 21159647 17174075
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 14.2916192471
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.954080065
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.5920734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.4619052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.4616835633
MESH:D002779 Cholestasis Cyclosporine 12.0219486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.0217333356 16919318 17110522 15861022 17681005 16105132 11677210
MESH:D002779 Cholestasis pirinixic acid 12.0219176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9715668235 15340226 8697196 12621046 16354765
MESH:D003092 Colitis resveratrol 3.8316474422
MESH:D003110 Colonic Neoplasms Fluorouracil 10.4218772588 17018589 17725105 17172411 15001691 17016597 16510598 17169374 17287894 16340194
MESH:D003110 Colonic Neoplasms Genistein 10.4217182828
MESH:D003110 Colonic Neoplasms irinotecan 10.4217287894 17725105
MESH:D003110 Colonic Neoplasms Quercetin 10.4219056647 19440933 17191121 16640504 15741050 11134977 17148506
MESH:D003110 Colonic Neoplasms resveratrol 10.4216338953
MESH:D015179 Colorectal Neoplasms Fluorouracil 6.1416391804 16303861 16282729 18383874 20501625 14970324 18448328 16331619 18802399 17454858 17695437 18509181 16524972 15289873 17401013 17016601 15148649 17594712 18288408 18949393 17255274 17094418
MESH:D015179 Colorectal Neoplasms irinotecan 6.1416391804 17454858 18259882 16303861 17159606 18509181 15273666
MESH:D015179 Colorectal Neoplasms Quercetin 6.1418095365 18852136
MESH:D015179 Colorectal Neoplasms resveratrol 6.1416550006
MESH:D015179 Colorectal Neoplasms Vinblastine 6.1418802399
MESH:D003139 Common Cold Ascorbic Acid 5.1617323712
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8017141729 14669216
MESH:D003327 Coronary Disease fluvastatin 8.2416142594
MESH:D003327 Coronary Disease resveratrol 8.2416507316
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.3710048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.378888407 17688650 16575769
MESH:D007644 Darier Disease Fluorouracil 4.4816733453
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0619031437
MESH:D017449 Dermatitis, Allergic Contact Mercury 3.5116823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2818249437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 7.7219496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 7.7216873680
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 9.5816506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 9.5820387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 9.5816647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 9.5817107852
MESH:D003928 Diabetic Nephropathies resveratrol 8.1816286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.1819279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 10.9516781746 19739265 14725611 11739529 12958197 10915739 12705907 15619225 17906064 12153990 11461765 10663392 18071297 18713872 11421492 14550746 17522070 19923254 19416960 12540782 15968718 11287661 12594235 2444490 19085960 11529661 16485898 19420014 14986274 11743745 16109766 16177239 11834606 19164858 19370779 16227642 16393943 12392966 10774834 16081117 17562736
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 10.957120509 10915739 15998439 15027814 6884620 15968718 17522070 19085960 3786805 2869522 11566570 16177239 19336974 21278145 7179309 7440962 4309450 6623471 10092053 3732212 9327722 16227642
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 10.9519107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 10.9520420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 10.951733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7819426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5311462148
MESH:D004421 Dystonia Phenobarbital 9.481851702
MESH:D004421 Dystonia Valproic Acid 9.481851702
MESH:C538011 Eales disease Ascorbic Acid 5.169068938
MESH:D004487 Edema perfluorooctanoic acid 14.2017259670 12083418
MESH:D004487 Edema pirinixic acid 14.2012083418
MESH:D004487 Edema resveratrol 14.208985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 14.2011000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.5916714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 13.6412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 13.6417872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 13.6419031437
MESH:D004714 Endometrial Hyperplasia Genistein 4.2816402032
MESH:D016889 Endometrial Neoplasms Genistein 6.8611473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 6.8616202921 17893378 20544844 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.769294722 10568697
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.5417923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 9.783659116
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 9.7817275665 3659116
MESH:D004828 Epilepsies, Partial Phenobarbital 8.9211558140 3922381
MESH:D004828 Epilepsies, Partial Valproic Acid 8.923922381 16628512
MESH:D004827 Epilepsy Phenobarbital 6.1320417680
MESH:D004827 Epilepsy Valproic Acid 6.1318234410 20417680
MESH:D004832 Epilepsy, Absence Phenobarbital 8.006401628
MESH:D004832 Epilepsy, Absence Valproic Acid 8.006426943 6254150 7562514
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 10.297750514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 10.297750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 9.443659116
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 9.443659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.8016302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.7220426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.7216530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 6.7216337965 16481741 16785472 17638652 15173087
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.7811564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 32.7116239168 16045604 17595544 15959796 61145 12631006 19224547 12795759
MESH:D005234 Fatty Liver Cyclosporine 32.7119224547
MESH:D005234 Fatty Liver Diethylnitrosamine 32.7120387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 32.7115345470
MESH:D005234 Fatty Liver pirinixic acid 32.7119236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 32.7119224547 14986274
MESH:D005234 Fatty Liver Valproic Acid 32.7119224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0516709447
MESH:D005264 Femoral Fractures zoledronic acid 5.5216234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1511858732
MESH:D005315 Fetal Diseases Valproic Acid 4.5716575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.8418558336 8888407
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.2214745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.8719069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.6314633661 10962813
MESH:D005355 Fibrosis Carbon Tetrachloride 18.6518705752
MESH:D005355 Fibrosis Cyclosporine 18.6512168785 12639820
MESH:D005355 Fibrosis Quercetin 18.6519474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 18.6520067830
MESH:D005756 Gastritis Acetaminophen 3.3616983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.918708960
MESH:D005909 Glioblastoma Genistein 10.8916598420
MESH:D005909 Glioblastoma Manganese 10.8917043766
MESH:D005909 Glioblastoma Quercetin 10.8919804834
MESH:D005910 Glioma Fluorouracil 5.7616145905
MESH:D005910 Glioma Quercetin 5.7617643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2810696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.1818337622 15162350 15102660
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 10.2516080930
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.2520471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.2511294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.3520558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0611000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.3019900420 19110552
MESH:D006529 Hepatomegaly perfluorooctanoic acid 18.193609246
MESH:D006529 Hepatomegaly Phenobarbital 18.1916109766
MESH:D006529 Hepatomegaly pirinixic acid 18.1916221962 18467677 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 18.1915340226 12621046 16120746
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 3.3616863852 16490937
MESH:D006561 Herpes Simplex resveratrol 3.8716876885
MESH:D006689 Hodgkin Disease Vinblastine 3.7818180244 18501091
MESH:D006849 Hydrocephalus Valproic Acid 4.5617688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.7315340226 8697196 18606429 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 11.8216870215
MESH:D006930 Hyperalgesia perfluorooctanoic acid 11.8212083418
MESH:D006930 Hyperalgesia zoledronic acid 11.8216769263
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.2216899240
MESH:D006934 Hypercalcemia zoledronic acid 4.7718089816 19622757
MESH:D006937 Hypercholesterolemia resveratrol 3.7317188708
MESH:D006943 Hyperglycemia pirinixic acid 8.3520558911
MESH:D006943 Hyperglycemia Quercetin 8.3511834736 18262572
MESH:D006949 Hyperlipidemias resveratrol 3.7416873680
MESH:D006973 Hypertension Cyclosporine 7.8610903974
MESH:D006973 Hypertension Quercetin 7.8618356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.8618850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7815338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.0317488730
MESH:D006996 Hypocalcemia zoledronic acid 5.8812669777
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5116569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.3417600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.2817937319
MESH:D007249 Inflammation Diethylnitrosamine 14.1318785209
MESH:D007249 Inflammation perfluorooctanoic acid 14.1312083418
MESH:D007249 Inflammation resveratrol 14.1316366677
MESH:D007249 Inflammation Tamoxifen 14.1319457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 14.1312200463 12878042
MESH:D007251 Influenza, Human Quercetin 10.1416624496
MESH:D007251 Influenza, Human resveratrol 10.1416624496
MESH:D007333 Insulin Resistance pirinixic acid 2.4316306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.0616580747
MESH:D007627 Keloid Quercetin 4.6517086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1315604871
MESH:D007674 Kidney Diseases Acetaminophen 13.0015629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 13.008314463 10903974 18776723
MESH:D007674 Kidney Diseases Mercury 13.0017934191
MESH:D007674 Kidney Diseases Quercetin 13.0016962696
MESH:D007680 Kidney Neoplasms Cyclosporine 10.9712371664
MESH:D007680 Kidney Neoplasms Fluorouracil 10.9716985049
MESH:D007680 Kidney Neoplasms Tamoxifen 10.9718625569
MESH:D007938 Leukemia Genistein 6.0318980019 17468513
MESH:D007938 Leukemia Quercetin 6.0317468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 4.4918089816
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1016294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.3816087638
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.928812269
MESH:D008064 Lipidoses Tamoxifen 2.9417567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.0211408273 11903743 16239168 17157831 21278145 16943688 17174718 17334410 16221502
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.0218665156 18407596 18522880 20032147 19638242
MESH:D008103 Liver Cirrhosis Phenobarbital 10.0221047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 8.1818166357 16033810 14716833 17525996 15057751 18418968 16136751 16097048 18054572 15893842 14512876 13678700 17481882 18205269 18006644 17900296 17869086 18279442 15925388 17721639 14724832 10355542 12389079 18263696 15370692 15650968 18277467 15052691 12445418 15959796 14716496 17565644 18420326 18156304 14748882 18429990 17823541 18317297 20821823 17976157 12609069 16027843 14620537 16011737 18481824 15876570 17698563 16116963 12666154 12445421 18395095 17640975 11481614 12667390 18705752 18412020 18472332 17708605 17944888 12586293 16015684 18376398 18210741 15996030 15362042 12898905 12741479 15818738 16638106 12632514 17557913 12649538 15730626 17805973 17922224 17766677 18472094 18395914 18339082 12546737 17714472 15123356 17761835 16248980 15931870 18251166 15673190 12632512 16192424 18187930 17631135 12958196 15338365
MESH:D008106 Liver Cirrhosis, Experimental Genistein 8.1817823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 8.1815474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 8.1812741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 8.1818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.1812878042
MESH:D008107 Liver Diseases Acetaminophen 8.6419784758 11587558 19460945 16610002 19014921 16611625 12969438 12587719
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.6415720792 16246199 15830285 16964402 17285989
MESH:D008107 Liver Diseases Diethylnitrosamine 8.6417034775
MESH:D008107 Liver Diseases Phenobarbital 8.6419363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8615123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.5217185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.5216899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 40.2818177683 15890375 2125692 9163691
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 40.2820195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 40.2819294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 40.2820434301 19254457 16942905 21278145 18978307 19426721 20118626 21071580 20501860 18648771 15885732 19642983 19996281 20137499 19427195 19255062 19256749 20101389 19090486 18977376 20405173 19294768 2422723 2862719 9163691 15175105 19551842 19638242 20492335 20583210 10737359 19499222 19850985 21167192 12112319 20452335 19690152 19812893 19073162 18754104 12771043 21047994 18644402 19833225
MESH:D008113 Liver Neoplasms Fluorouracil 40.2817045692 15113037 18383874 16603448
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 40.2814757943 18709148
MESH:D008113 Liver Neoplasms Phenobarbital 40.2815975961 19812893 19482888 19073162 8742319 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 40.2815890375 20007298 16377806
MESH:D008113 Liver Neoplasms Quercetin 40.2818980244
MESH:D008113 Liver Neoplasms resveratrol 40.2820405173 19812893 19321006 19073162
MESH:D008113 Liver Neoplasms Tamoxifen 40.2816684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 40.2816984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 29.918603461
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 29.9118544905
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 29.9115583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 29.9117854601 18775883 21159647 18544905 17174075 18093689 19004024 19126423 18253720 3124819 18164116 18079962 17942915 18308698 2563599 16267830 19519916 16842330 18282651 19009564 19539802 9362446
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 29.91598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 29.9117172636 18308698 1399818 6150874 2563599
MESH:D008114 Liver Neoplasms, Experimental Quercetin 29.9119519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 29.9112151625
MESH:D008171 Lung Diseases Ascorbic Acid 7.1116863852
MESH:D008171 Lung Diseases Ozone 7.118266340 19066396
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.9517228818
MESH:D055370 Lung Injury Ozone 3.5520417186
MESH:D008175 Lung Neoplasms Aflatoxin B1 17.0214755239
MESH:D008175 Lung Neoplasms Ascorbic Acid 17.0216401635
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 17.0217053015 18816296 6695378 18569708 20064080 20464547 20135361 18520028 20869020
MESH:D008175 Lung Neoplasms Diethylnitrosamine 17.0220970405 20512841 6695378 21163286
MESH:D008175 Lung Neoplasms Fluorouracil 17.0215246190
MESH:D008175 Lung Neoplasms Methylcholanthrene 17.0220970405 11893704 1399818 15390079 9230183 20512841 16271038 10545420 7750092 16337739 21163286 6695378 17909032
MESH:D008175 Lung Neoplasms Ozone 17.028597069 7614698
MESH:D008175 Lung Neoplasms Quercetin 17.0216280456
MESH:D008175 Lung Neoplasms Tamoxifen 17.0218625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 17.0211884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.4815086387
MESH:D016393 Lymphoma, B-Cell resveratrol 4.0117088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.6214749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 8.9715688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 8.9719428831
MESH:D008325 Mammary Neoplasms, Experimental Genistein 12.7112929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 12.718985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 12.7119196722 11731420 14580682 16827153 19196723
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 12.7117312309
MESH:D020149 Manganese Poisoning Manganese 11.9716551646 19453300 16568477
MESH:D020149 Manganese Poisoning Tamoxifen 11.9719453300
MESH:D008545 Melanoma resveratrol 4.9217992120
MESH:D008545 Melanoma Tamoxifen 4.9212393984 19393235
MESH:D008545 Melanoma Vinblastine 4.9216248763 18176117 15577320 18332650 12374674 15577323 17761969 16432458 16809738 18505091
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.8715990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2619513568
MESH:D008654 Mesothelioma zoledronic acid 3.6316675582
MESH:D008659 Metabolic Diseases resveratrol 4.1017112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4716801185
MESH:D008679 Metaplasia Ozone 4.7910496685
MESH:D008881 Migraine Disorders Valproic Acid 2.9718765137 18803445
MESH:D009041 Motion Sickness Dextroamphetamine 5.211613127
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.7516381670
MESH:D009062 Mouth Neoplasms Fluorouracil 7.7516757204 18986760
MESH:D009069 Movement Disorders Manganese 4.7216551646
MESH:D052016 Mucositis irinotecan 4.7017159606
MESH:D009101 Multiple Myeloma fluvastatin 11.2016996129
MESH:D009101 Multiple Myeloma resveratrol 11.2014749477 16267019 17049120 17164350 17935668 16490592
MESH:D009101 Multiple Myeloma zoledronic acid 11.2018089719 16996129 19621390
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.5617962980
MESH:D009135 Muscular Diseases pirinixic acid 3.2016239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.758888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 2.9817596541
MESH:D009203 Myocardial Infarction Genistein 12.4817141266
MESH:D009203 Myocardial Infarction pirinixic acid 12.4819151258
MESH:D009203 Myocardial Infarction Quercetin 12.4819595682
MESH:D009203 Myocardial Infarction resveratrol 12.4817188708 16317513 16525036 17015251 17125593 16456233
MESH:D017202 Myocardial Ischemia resveratrol 8.2017125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.2012213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.8817141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.8816411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 12.8819207477
MESH:D009205 Myocarditis resveratrol 4.4517322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.1617484760
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 12.609029167 3581430
MESH:D009362 Neoplasm Metastasis irinotecan 12.6018259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 12.6019393235
MESH:D009362 Neoplasm Metastasis zoledronic acid 12.6019139120 17312309 15867366
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4119410462
MESH:D009369 Neoplasms Benzo(a)pyrene 10.5711141357
MESH:D009369 Neoplasms Fluorouracil 10.5718600527 18239605 16928823
MESH:D009369 Neoplasms pirinixic acid 10.5717405874
MESH:D009369 Neoplasms Quercetin 10.5715185748
MESH:D009374 Neoplasms, Experimental resveratrol 3.708985016
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.6819189210 19200415 19196722
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1317954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0319348381 18481113
MESH:D009410 Nerve Degeneration Manganese 4.0416551646
MESH:D009421 Nervous System Malformations Genistein 8.6216427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.6214600291
MESH:D009436 Neural Tube Defects Valproic Acid 2.938888407 16359493
MESH:D009447 Neuroblastoma irinotecan 3.328761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 12.6018514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 12.6020387270
MESH:D019636 Neurodegenerative Diseases resveratrol 12.6017652729
MESH:D017599 Neuroectodermal Tumors irinotecan 4.428761367
MESH:D020078 Neurogenic Inflammation Quercetin 9.7417929310
MESH:D020078 Neurogenic Inflammation resveratrol 9.7417929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.8020387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 7.8516436463
MESH:D020258 Neurotoxicity Syndromes Malathion 7.8515081274
MESH:D009503 Neutropenia Vinblastine 4.2917378895
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.659802331
MESH:D009765 Obesity Ascorbic Acid 4.4717217161
MESH:D009765 Obesity pirinixic acid 4.4720558911
MESH:D010014 Osteolysis zoledronic acid 5.0615867366
MESH:D010018 Osteomalacia Phenobarbital 4.0517016548
MESH:D010024 Osteoporosis Genistein 6.9319401787
MESH:D010024 Osteoporosis zoledronic acid 6.9317882678
MESH:D015663 Osteoporosis, Postmenopausal Genistein 15.2416169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 15.2419495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 15.2417513867
MESH:D010051 Ovarian Neoplasms Genistein 4.7519005980
MESH:D010051 Ovarian Neoplasms Quercetin 4.7519005980
MESH:D010146 Pain Acetaminophen 6.1516870215
MESH:D010146 Pain zoledronic acid 6.1516475674
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 11.3916540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 11.3916929163 19003803 15113037 16500647
MESH:D010190 Pancreatic Neoplasms Phenobarbital 11.3916965848
MESH:D010190 Pancreatic Neoplasms Quercetin 11.3916965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4011578682
MESH:D010300 Parkinson Disease Manganese 3.2611181820
MESH:D020734 Parkinsonian Disorders Manganese 4.2016140633
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9312520081
MESH:D010538 Peritonitis Ozone 3.8316369182
MESH:D011014 Pneumonia Ozone 4.0818007984 18929643 18381685
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2618163543
MESH:D011230 Precancerous Conditions Cyclosporine 19.7412371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 19.742563599
MESH:D011230 Precancerous Conditions Phenobarbital 19.742563599
MESH:D011230 Precancerous Conditions Quercetin 19.7419056647
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 20.7117132714
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 20.7116679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 20.7111222880 11399792 11896295 11118676
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 20.7120603192
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0517292933
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.0519082440 18626508
MESH:D011471 Prostatic Neoplasms Genistein 2.0516925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms Quercetin 2.0517292933 14715546
MESH:D011471 Prostatic Neoplasms resveratrol 2.0515767336 17675339 17718901 17804756 16731767 17636462
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0515067354
MESH:D011471 Prostatic Neoplasms zoledronic acid 2.0519103299 12438248
MESH:D011537 Pruritus Ethinyl Estradiol 3.0016919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 11.1412752131
MESH:D019310 Pseudolymphoma Valproic Acid 11.1412752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.1216882103
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 5.0214606601
MESH:D012004 Rectal Neoplasms Fluorouracil 3.7516160472 15538739 18722050 18286688
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.2716325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.0619058328
MESH:D015427 Reperfusion Injury resveratrol 6.0615827377 17520802 17058453 16314181 16317513
MESH:D012135 Respiratory Sounds Malathion 4.9717119214 11874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5418990726
MESH:D012140 Respiratory Tract Diseases Malathion 5.2117119214
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.2216849425
MESH:D012208 Rhabdomyosarcoma Valproic Acid 3.8919155313
MESH:D012512 Sarcoma, Ewing's zoledronic acid 4.6416121404
MESH:D012554 Schistosomiasis japonica Quercetin 5.2316862918
MESH:D012559 Schizophrenia Valproic Acid 2.0315737665 19110320
MESH:D012640 Seizures Phenobarbital 5.3111442880 4039156 3137016 16876388
MESH:D012640 Seizures Valproic Acid 5.313137016 17978042 11738929 15475178 11044598 16876388 1511512 14763951
MESH:D003294 Seizures, Febrile Phenobarbital 4.516407741
MESH:D012871 Skin Diseases Ascorbic Acid 3.1318709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 8.5710029692 19755658
MESH:D012878 Skin Neoplasms resveratrol 8.5715837718 8985016
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.5716192470
MESH:D013088 Spermatocele Ethinyl Estradiol 10.5116709447
MESH:D013088 Spermatocele Tamoxifen 10.5116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.7319457130
MESH:D016135 Spinal Dysraphism Valproic Acid 3.5419490988
MESH:D013226 Status Epilepticus Valproic Acid 4.2312833885
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.462093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.4618456281
MESH:D013274 Stomach Neoplasms Fluorouracil 4.4615786421 17522103 17498489 16424979 18567086 19015929 19084572 18396642 17172411 16951190
MESH:D013274 Stomach Neoplasms irinotecan 4.4615723263
MESH:D013276 Stomach Ulcer Ascorbic Acid 3.6218726076
MESH:D020521 Stroke Ascorbic Acid 4.0516403987 16517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.2116321402
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3311994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8915669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5912697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.417505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 6.411399818
MESH:D014062 Tongue Neoplasms Fluorouracil 9.0916280240
MESH:D014062 Tongue Neoplasms resveratrol 9.0916227395
MESH:D014178 Translocation, Genetic Valproic Acid 4.9217262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.213119515
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 7.6117053015
MESH:D001749 Urinary Bladder Neoplasms Quercetin 7.6116720314
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 7.618653321 16712894 17572228
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.348888407
MESH:D014581 Urticaria Acetaminophen 2.6910982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 8.7216803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 8.7217473185
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.5214692618
MESH:D014594 Uterine Neoplasms resveratrol 8.5217044934
MESH:D014605 Uveitis Cyclosporine 3.671336536
MESH:D014625 Vaginal Neoplasms Vinblastine 4.7415577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2812125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2614671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.0017488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9315886252
MESH:D014985 Xerophthalmia Cyclosporine 4.1317120751
Pathway ID Pathway Name
KEGG:04110 Cell cycle
REACT:152 Cell Cycle, Mitotic
REACT:383 DNA Replication
KEGG:04114 Oocyte meiosis
KEGG:04914 Progesterone-mediated oocyte maturation
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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