AutismKB 2.0

Annotation Detail for TEAD1


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Basic Information Top
Gene Symbol:TEAD1 ( AA,FLJ17970,NTEF-1,REF1,TCF-13,TCF13,TEAD-1,TEF-1 )
Gene Full Name: TEA domain family member 1 (SV40 transcriptional enhancer factor)
Band: 11p15.3
Quick LinksEntrez ID:7003; OMIM: 189967; Uniprot ID:TEAD1_HUMAN; ENSEMBL ID: ENSG00000187079; HGNC ID: 11714
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
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Desease Name
Sveinsson choreoretinal atrophy
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C031903 1-UFT protocol TEAD1 protein results in decreased susceptibility to 1-UFT protocoldecreases response to substance 16734730
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of TEAD1 mRNAincreases expression 18648102
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of TEAD1 mRNAdecreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TEAD1 mRNAdecreases expression 20018196
19150397
C110904 capecitabine TEAD1 protein results in decreased susceptibility to capecitabinedecreases response to substance 16734730
C025034 doxifluridine TEAD1 protein results in decreased susceptibility to doxifluridinedecreases response to substance 16734730
D009151 Mustard Gas Mustard Gas results in increased expression of TEAD1 mRNAincreases expression 15674843
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0420464547 20127859
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 7.093712494
MESH:D000236 Adenoma Benzo(a)pyrene 7.096695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4319183758
MESH:D001249 Asthma Mustard Gas 2.7810378619
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.461440618 11289319
MESH:D001768 Blister Mustard Gas 5.5619167455
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.6320146248 17474063
MESH:D001943 Breast Neoplasms capecitabine 2.6318473752 12972520
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.5615286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 5.4210378619 17687719
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 1.777296757 3581430
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.787296757
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1120419170
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 7.267505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.2620889678
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.359022650 19486331
MESH:D015179 Colorectal Neoplasms capecitabine 3.3218473752 18448328
MESH:D003329 Coronary Vasospasm capecitabine 6.1417465463
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.1518759878 8156756 2524372 14531868 8970840 12868966 11298694 11906362
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.792952479 3621924
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 2.0218692083 1440618 18289764 6679447 9022650 9328219 9653073 7440962 8291058 16192314 11289319 18648102 6482804
MESH:D004487 Edema Mustard Gas 3.599260866 11402378 11428647 11428631
MESH:D004890 Erythema Mustard Gas 5.569357497
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.533581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.5320426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.5316530937
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.466705139
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.347505956
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.7820471113
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.846705139
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.3015034207
MESH:D007249 Inflammation Mustard Gas 2.9117524151 8975870 9357497 16001271 11428620 9260866 11402378 11428647 11428631
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.469022650 8074119
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.206582329
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.3515034207 9327722
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1221137059 20195826
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.693712494 598648 6587162 1399818
MESH:D008171 Lung Diseases Mustard Gas 3.6218702808 18161513
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.5918569708 20869020 18816296 17053015 20135361 20064080 6695378 20464547 18520028
MESH:D008175 Lung Neoplasms Mustard Gas 2.598781369 3148597
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4016381670
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 6.593581430
MESH:D009362 Neoplasm Metastasis capecitabine 6.5912972520
MESH:D009369 Neoplasms Benzo(a)pyrene 5.9511141357
MESH:D009369 Neoplasms capecitabine 5.9516374040
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.086679447
MESH:D009503 Neutropenia Mustard Gas 4.2716761898 7688884
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.684026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.463988306
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.847296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.916228378
MESH:D011041 Poisoning Mustard Gas 4.1015727166
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9317292933
MESH:D011537 Pruritus Mustard Gas 4.4918058305
MESH:D011658 Pulmonary Fibrosis Mustard Gas 3.0117720292 17266442 17620002 17894541 10334151
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.583692021
MESH:D012871 Skin Diseases Mustard Gas 2.7712880345 15451306 16961503
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4810029692 19755658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
OMIM:108985 SVEINSSON CHORIORETINAL ATROPHY marker/mechanism
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.091399818 6582329 3712494 7505956 6587162
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 5.278074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.2717053015
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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