AutismKB 2.0

Annotation Detail for TERT


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Basic Information Top
Gene Symbol:TERT ( EST2,TCS1,TP2,TRT,hEST2 )
Gene Full Name: telomerase reverse transcriptase
Band: 5p15.33
Quick LinksEntrez ID:7015; OMIM: 187270; Uniprot ID:TERT_HUMAN; ENSEMBL ID: ENSG00000164362; HGNC ID: 11730
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Chromosome Maintenance
Pathway IDPathway Name
200106Regulation of Wnt-mediated beta catenin signaling and target gene transcription
200099IL2 signaling events mediated by PI3K
200172HIF-1-alpha transcription factor network
200072Regulation of Telomerase
200045Validated targets of C-MYC transcriptional activation
No data
Pathway IDPathway Name
500667Telomere Extension By Telomerase
Related Diseases/Disorders Top
No data
No data
Desease Name
HEMATOLOGICAL
CARDIOVASCULAR
CANCER
Glioma
lung adenocarcinoma
aplastic anaemia
lung cancer
idiopathic pulmonary fibrosis
Desease Name
Idiopathic pulmonary fibrosis
Hematological and biochemical traits
Lung adenocarcinoma
Testicular germ cell cancer
Lung cancer
Glioma
Desease Name
Dyskeratosis congenita
Aplastic anemia, susceptibility to
Pulmonary fibrosis,idiopathic, susceptibility to
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased activity of TERT protein]decreases reaction|increases activity 16798746
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene results in increased activity of TERT protein]decreases reaction|increases activity 16798746
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased activity of TERT protein]decreases reaction|increases activity 15590986
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene results in increased activity of TERT protein]decreases reaction|increases activity 15590986
C434003 3-(4-methylphenylsulfonyl)-2-propenenitrile 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Raloxifene promotes the reaction [RELA protein binds to TERT protein]]affects binding|decreases reaction|increases reaction 16798746
C434003 3-(4-methylphenylsulfonyl)-2-propenenitrile 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Raloxifene results in increased activity of TERT protein]decreases reaction|increases activity 16798746
C048336 3-adenin-9-yl-2-hydroxypropanoic acid isobutyl ester 3-adenin-9-yl-2-hydroxypropanoic acid isobutyl ester affects the expression of TERT mRNAaffects expression 18045574
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane affects the expression of TERT mRNAaffects expression 18648102
C059356 5-fluoropyrimidin-2-one beta-ribofuranoside 5-fluoropyrimidin-2-one beta-ribofuranoside results in increased expression of TERT mRNAincreases expression 18045574
C016391 9-(2,3-dihydroxypropyl)adenine 9-(2,3-dihydroxypropyl)adenine results in increased expression of TERT mRNAincreases expression 18045574
C106538 abacavir abacavir results in decreased activity of TERT proteindecreases activity 19358275
D000111 Acetylcysteine Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased activity of TERT protein]decreases activity|decreases reaction 18336854
D000111 Acetylcysteine Acetylcysteine inhibits the reaction [monomethylarsonous acid results in decreased activity of TERT protein]decreases activity|decreases reaction 18336854
C103303 alitretinoin alitretinoin results in decreased expression of TERT mRNAdecreases expression 16180984
C068073 Am 580 [Am 580 co-treated with Retinoids] results in decreased expression of TERT mRNAaffects cotreatment|decreases expression 16482212
D000643 Ammonium Chloride Ammonium Chloride affects the expression of TERT mRNAaffects expression 16483693
D001151 Arsenic Arsenic results in increased expression of TERT mRNAincreases expression 19337508
C006632 arsenic trioxide arsenic trioxide inhibits the reaction [SP1 protein binds to TERT promoter]affects binding|decreases reaction 15761015
C006632 arsenic trioxide arsenic trioxide inhibits the reaction [SP1 protein results in increased expression of TERT mRNA]decreases reaction|increases expression 11714746
C006632 arsenic trioxide arsenic trioxide results in decreased activity of TERT mRNAdecreases activity 17275888
C006632 arsenic trioxide arsenic trioxide results in decreased activity of TERT proteindecreases activity 15996315
C006632 arsenic trioxide arsenic trioxide results in decreased expression of TERT mRNAdecreases expression 16129045
15761015
16966277
11714746
17275888
16285558
C006632 arsenic trioxide arsenic trioxide results in decreased expression of TERT proteindecreases expression 16966277
11714746
C006632 arsenic trioxide [arsenic trioxide results in increased abundance of Reactive Oxygen Species] which results in decreased expression of TERT mRNAdecreases expression|increases abundance 18336854
C006632 arsenic trioxide Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased activity of TERT protein]decreases activity|decreases reaction 18336854
C006632 arsenic trioxide arsenic trioxide results in decreased activity of TERT proteindecreases activity 18336854
C006632 arsenic trioxide CAT protein inhibits the reaction [arsenic trioxide results in decreased activity of TERT protein]decreases activity|decreases reaction 18336854
C006632 arsenic trioxide diphenyleneiodonium inhibits the reaction [arsenic trioxide results in decreased activity of TERT protein]decreases activity|decreases reaction 18336854
C045816 arsenic trisulfide arsenic trisulfide results in decreased activity of TERT proteindecreases activity 19811737
C045816 arsenic trisulfide arsenic trisulfide results in decreased expression of TERT mRNAdecreases expression 19811737
17643074
C045816 arsenic trisulfide TERT protein affects the susceptibility to arsenic trisulfideaffects response to substance 17643074
D001374 Azacitidine Azacitidine analog results in decreased expression of TERT mRNAdecreases expression 18045574
D001374 Azacitidine Azacitidine results in decreased activity of TERT proteindecreases activity 19451745
D001374 Azacitidine Azacitidine results in decreased expression of TERT mRNAdecreases expression 19451745
D001374 Azacitidine Azacitidine results in decreased methylation of TERT promoterdecreases methylation 19451745
D001374 Azacitidine E2F1 protein affects the reaction [Azacitidine results in decreased activity of TERT protein]affects reaction|decreases activity 19451745
D001374 Azacitidine E2F1 protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]affects reaction|decreases expression 19451745
D001374 Azacitidine MYC protein affects the reaction [Azacitidine results in decreased activity of TERT protein]affects reaction|decreases activity 19451745
D001374 Azacitidine MYC protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]affects reaction|decreases expression 19451745
C053541 bicalutamide bicalutamide results in decreased activity of TERT proteindecreases activity 15638997
C053541 bicalutamide bicalutamide results in decreased expression of TERT mRNAdecreases expression 15638997
C006780 bisphenol A bisphenol A results in increased expression of TERT mRNAincreases expression 15368248
D001761 Bleomycin TERT gene mutant form results in decreased susceptibility to Bleomycindecreases response to substance 18008008
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased activity of TERT proteinincreases activity 14729356
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of TERT mRNAincreases expression 16600092
D019256 Cadmium Chloride Selenium inhibits the reaction [Cadmium Chloride results in increased expression of TERT mRNA]decreases reaction|increases expression 16600092
D002794 Choline Choline affects the expression of TERT mRNAaffects expression 17616785
D019343 Citric Acid [Citric Acid co-treated with zinc chloride] results in decreased activity of TERT proteinaffects cotreatment|decreases activity 16624386
D003474 Curcumin Curcumin results in decreased activity of TERT proteindecreases activity 17096185
C014347 decitabine decitabine affects the expression of TERT mRNAaffects expression 18045574
C014347 decitabine decitabine affects the methylation of TERT promoteraffects methylation 17267411
C014347 decitabine decitabine affects the reaction [CTCF protein binds to TERT promoter]affects binding|affects reaction 17267411
C014347 decitabine decitabine affects the reaction [[CTCF protein binds to TERT promoter] which affects the expression of TERT mRNA]affects binding|affects expression|affects reaction 17267411
C014347 decitabine decitabine results in decreased activity of TERT proteindecreases activity 18021753
C014347 decitabine [decitabine results in decreased activity of TERT protein] which results in increased susceptibility to Cisplatindecreases activity|increases response to substance 18021753
C014347 decitabine [decitabine results in decreased activity of TERT protein] which results in increased susceptibility to Paclitaxeldecreases activity|increases response to substance 18021753
C014347 decitabine [decitabine results in decreased activity of TERT protein] which results in increased susceptibility to Tamoxifendecreases activity|increases response to substance 18021753
C014347 decitabine decitabine results in decreased expression of TERT proteindecreases expression 18021753
C061481 dibenzoylmethane dibenzoylmethane inhibits the reaction [ESR1 protein binds to TERT enhancer]affects binding|decreases reaction 16051634
C061481 dibenzoylmethane dibenzoylmethane inhibits the reaction [Estradiol results in increased expression of TERT mRNA]decreases reaction|increases expression 16051634
D002945 Cisplatin Cisplatin results in decreased expression of TERT mRNAdecreases expression 17923759
D002945 Cisplatin Cisplatin results in increased expression of and results in decreased activity of TERT proteindecreases activity|increases expression 17923759
D002945 Cisplatin [decitabine results in decreased activity of TERT protein] which results in increased susceptibility to Cisplatindecreases activity|increases response to substance 18021753
D004052 Diethylnitrosamine ATM protein promotes the reaction [Diethylnitrosamine results in increased expression of TERT protein]increases expression|increases reaction 19919837
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of TERT proteinincreases expression 19919837
D004121 Dimethyl Sulfoxide Dimethyl Sulfoxide results in decreased expression of TERT mRNAdecreases expression 16180984
C007517 diphenyleneiodonium diphenyleneiodonium inhibits the reaction [arsenic trioxide results in decreased activity of TERT protein]decreases activity|decreases reaction 18336854
C007517 diphenyleneiodonium diphenyleneiodonium inhibits the reaction [monomethylarsonous acid results in decreased activity of TERT protein]decreases activity|decreases reaction 18336854
D004317 Doxorubicin Doxorubicin results in decreased expression of TERT mRNAdecreases expression 16077987
D004317 Doxorubicin Doxorubicin results in decreased expression of TERT mRNA alternative formdecreases expression 15003732
D004317 Doxorubicin Doxorubicin results in increased expression of TERT mRNAincreases expression 18560228
D004317 Doxorubicin TERT mRNA results in decreased susceptibility to Doxorubicindecreases response to substance 18396642
D004365 Drugs, Chinese Herbal Drugs, Chinese Herbal results in decreased activity of TERT proteindecreases activity 19295228
D004365 Drugs, Chinese Herbal Drugs, Chinese Herbal results in decreased expression of TERT mRNAdecreases expression 19295228
C479799 (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide results in decreased expression of TERT mRNAdecreases expression 15528975
D004610 Ellagic Acid Ellagic Acid inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form]decreases reaction|increases expression 19501078
D004610 Ellagic Acid Ellagic Acid results in increased expression of TERT mRNA alternative formincreases expression 19501078
D004726 Endosulfan Endosulfan results in increased expression of TERT mRNAincreases expression 15832825
D004726 Endosulfan Endosulfan results in increased expression of TERT mRNAincreases expression 15832825
C045651 epigallocatechin gallate epigallocatechin gallate results in decreased expression of TERT mRNAdecreases expression 18581255
C045651 epigallocatechin gallate epigallocatechin gallate results in decreased expression of TERT proteindecreases expression 18581255
D004958 Estradiol 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased activity of TERT protein]decreases reaction|increases activity 16798746
D004958 Estradiol dibenzoylmethane inhibits the reaction [Estradiol results in increased expression of TERT mRNA]decreases reaction|increases expression 16051634
D004958 Estradiol Ellagic Acid inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form]decreases reaction|increases expression 19501078
D004958 Estradiol Estradiol results in increased activity of TERT proteinincreases activity 16798746
16327978
19561322
D004958 Estradiol Estradiol results in increased expression of TERTincreases expression 15585566
D004958 Estradiol Estradiol results in increased expression of TERT mRNAincreases expression 16051634
16327978
D004958 Estradiol Estradiol results in increased expression of TERT mRNA alternative formincreases expression 19501078
D004958 Estradiol fulvestrant inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form]decreases reaction|increases expression 19501078
D004958 Estradiol Metribolone inhibits the reaction [Estradiol results in increased activity of TERT protein]decreases reaction|increases activity 19561322
D004958 Estradiol Tamoxifen inhibits the reaction [Estradiol results in increased activity of TERT protein]decreases reaction|increases activity 19561322
D004958 Estradiol Tamoxifen inhibits the reaction [Estradiol results in increased expression of TERT mRNA]decreases reaction|increases expression 16051634
D004958 Estradiol Tamoxifen inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form]decreases reaction|increases expression 19501078
D004958 Estradiol [Tetrachlorodibenzodioxin co-treated with Estradiol] results in increased activity of TERT proteinaffects cotreatment|increases activity 16327978
D004958 Estradiol [Tetrachlorodibenzodioxin co-treated with Estradiol] results in increased expression of TERT mRNAaffects cotreatment|increases expression 16327978
D004958 Estradiol 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased activity of TERT protein]decreases reaction|increases activity 15590986
D004958 Estradiol Estradiol promotes the reaction [TERT protein binds to RELA protein]affects binding|increases reaction 15590986
D004958 Estradiol Estradiol results in increased phosphorylation of and results in increased activity of TERT proteinincreases activity|increases phosphorylation 15590986
D005472 Fluorouracil [Fluorouracil co-treated with gemcitabine] results in decreased activity of TERT proteinaffects cotreatment|decreases activity 16929163
D005472 Fluorouracil Fluorouracil results in decreased activity of TERT proteindecreases activity 16929163
D005472 Fluorouracil Fluorouracil results in decreased expression of TERT mRNAdecreases expression 17923759
17996122
16455633
D005472 Fluorouracil Fluorouracil results in decreased expression of TERT mRNA alternative formdecreases expression 15003732
D005472 Fluorouracil Fluorouracil results in decreased expression of TERT protein modified formdecreases expression 16455633
D005472 Fluorouracil TERT mRNA results in decreased susceptibility to Fluorouracildecreases response to substance 18396642
D005472 Fluorouracil TERT protein affects the susceptibility to Fluorouracilaffects response to substance 15608686
D005472 Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of TERT mRNA]affects reaction|decreases expression 15016801
C070081 fulvestrant fulvestrant inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form]decreases reaction|increases expression 19501078
C070081 fulvestrant fulvestrant results in decreased expression of TERT mRNA alternative formdecreases expression 19501078
C056507 gemcitabine [Fluorouracil co-treated with gemcitabine] results in decreased activity of TERT proteinaffects cotreatment|decreases activity 16929163
C056507 gemcitabine gemcitabine results in decreased activity of TERT proteindecreases activity 16929163
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of TERT mRNAdecreases expression 15761015
D007501 Iron Iron results in increased activity of TERT proteinincreases activity 17189828
C067431 letrozole letrozole inhibits the reaction [Metribolone results in increased activity of TERT protein]decreases reaction|increases activity 19561322
C013592 mangiferin mangiferin results in decreased activity of TERT proteindecreases activity 17634039
D015741 Metribolone letrozole inhibits the reaction [Metribolone results in increased activity of TERT protein]decreases reaction|increases activity 19561322
D015741 Metribolone Metribolone inhibits the reaction [Estradiol results in increased activity of TERT protein]decreases reaction|increases activity 19561322
D015741 Metribolone Metribolone results in increased activity of TERT proteinincreases activity 19561322
D015741 Metribolone Metribolone results in increased expression of TERT mRNAincreases expression 19561322
D015741 Metribolone Tamoxifen inhibits the reaction [Metribolone results in increased activity of TERT protein]decreases reaction|increases activity 19561322
C406082 monomethylarsonous acid [monomethylarsonous acid results in increased abundance of Reactive Oxygen Species] which results in decreased expression of TERT mRNAdecreases expression|increases abundance 18336854
C406082 monomethylarsonous acid Acetylcysteine inhibits the reaction [monomethylarsonous acid results in decreased activity of TERT protein]decreases activity|decreases reaction 18336854
C406082 monomethylarsonous acid CAT protein inhibits the reaction [monomethylarsonous acid results in decreased activity of TERT protein]decreases activity|decreases reaction 18336854
C406082 monomethylarsonous acid diphenyleneiodonium inhibits the reaction [monomethylarsonous acid results in decreased activity of TERT protein]decreases activity|decreases reaction 18336854
C406082 monomethylarsonous acid monomethylarsonous acid results in decreased activity of TERT proteindecreases activity 18336854
C003297 nandrolone decanoate nandrolone decanoate results in increased activity of TERT proteinincreases activity 19561322
D017239 Paclitaxel [decitabine results in decreased activity of TERT protein] which results in increased susceptibility to Paclitaxeldecreases activity|increases response to substance 18021753
D020849 Raloxifene 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene results in increased activity of TERT protein]decreases reaction|increases activity 16798746
D020849 Raloxifene 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Raloxifene promotes the reaction [RELA protein binds to TERT protein]]affects binding|decreases reaction|increases reaction 16798746
D020849 Raloxifene 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Raloxifene results in increased activity of TERT protein]decreases reaction|increases activity 16798746
D020849 Raloxifene ESR1 protein promotes the reaction [Raloxifene results in increased activity of TERT protein]increases activity|increases reaction 16798746
D020849 Raloxifene ESR2 protein promotes the reaction [Raloxifene results in increased activity of TERT protein]increases activity|increases reaction 16798746
D020849 Raloxifene Raloxifene promotes the reaction [RELA protein binds to TERT protein]affects binding|increases reaction 16798746
D020849 Raloxifene Raloxifene results in increased expression of and results in increased activity of TERT proteinincreases activity|increases expression 16798746
D020849 Raloxifene Raloxifene results in increased expression of TERT mRNAincreases expression 16798746
D020849 Raloxifene Raloxifene results in increased phosphorylation of TERT proteinincreases phosphorylation 16798746
D020849 Raloxifene SN50 peptide inhibits the reaction [Raloxifene results in increased activity of TERT protein]decreases reaction|increases activity 16798746
D020849 Raloxifene 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene results in increased activity of TERT protein]decreases reaction|increases activity 15590986
D020849 Raloxifene Raloxifene promotes the reaction [TERT protein binds to RELA protein]affects binding|increases reaction 15590986
D020849 Raloxifene Raloxifene results in increased phosphorylation of and results in increased activity of TERT proteinincreases activity|increases phosphorylation 15590986
D017382 Reactive Oxygen Species [arsenic trioxide results in increased abundance of Reactive Oxygen Species] which results in decreased expression of TERT mRNAdecreases expression|increases abundance 18336854
D017382 Reactive Oxygen Species [monomethylarsonous acid results in increased abundance of Reactive Oxygen Species] which results in decreased expression of TERT mRNAdecreases expression|increases abundance 18336854
D017382 Reactive Oxygen Species Reactive Oxygen Species affects the expression of TERT mRNAaffects expression 15761015
D015474 Isotretinoin Isotretinoin results in decreased expression of TERT mRNAdecreases expression 16180984
D012176 Retinoids [Am 580 co-treated with Retinoids] results in decreased expression of TERT mRNAaffects cotreatment|decreases expression 16482212
D012643 Selenium Selenium results in decreased activity of TERT proteindecreases activity 17948765
D012643 Selenium Selenium results in decreased expression of TERT mRNAdecreases expression 17948765
D012643 Selenium Selenium inhibits the reaction [Cadmium Chloride results in increased expression of TERT mRNA]decreases reaction|increases expression 16600092
D017632 Asbestos, Serpentine TERT protein results in increased susceptibility to Asbestos, Serpentineincreases response to substance 15182483
D020123 Sirolimus Sirolimus results in decreased expression of TERT proteindecreases expression 17996122
C118258 SN50 peptide SN50 peptide inhibits the reaction [Raloxifene results in increased activity of TERT protein]decreases reaction|increases activity 16798746
C017947 sodium arsenite sodium arsenite results in decreased expression of TERT mRNAdecreases expression 16966277
19464579
C017947 sodium arsenite sodium arsenite results in decreased expression of TERT proteindecreases expression 16966277
19464579
C017947 sodium arsenite sodium arsenite results in increased expression of TERT mRNAincreases expression 19464579
19337508
D018038 Sodium Selenite Sodium Selenite results in increased activity of TERT proteinincreases activity 14673504
D018038 Sodium Selenite Sodium Selenite results in increased expression of TERT mRNAincreases expression 14673504
D013629 Tamoxifen [decitabine results in decreased activity of TERT protein] which results in increased susceptibility to Tamoxifendecreases activity|increases response to substance 18021753
D013629 Tamoxifen Tamoxifen inhibits the reaction [Estradiol results in increased activity of TERT protein]decreases reaction|increases activity 19561322
D013629 Tamoxifen Tamoxifen inhibits the reaction [Estradiol results in increased expression of TERT mRNA]decreases reaction|increases expression 16051634
D013629 Tamoxifen Tamoxifen inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form]decreases reaction|increases expression 19501078
D013629 Tamoxifen Tamoxifen inhibits the reaction [Metribolone results in increased activity of TERT protein]decreases reaction|increases activity 19561322
D013629 Tamoxifen Tamoxifen results in decreased expression of TERT mRNA alternative formdecreases expression 19501078
D013749 Tetrachlorodibenzodioxin CYP1A1 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of TERT mRNA]affects reaction|increases expression 17141429
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Estradiol] results in increased activity of TERT proteinaffects cotreatment|increases activity 16327978
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Estradiol] results in increased expression of TERT mRNAaffects cotreatment|increases expression 16327978
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased activity of TERT proteinincreases activity 16327978
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of TERT mRNAincreases expression 16327978
17141429
D013749 Tetrachlorodibenzodioxin MYC protein affects the reaction [Tetrachlorodibenzodioxin results in increased activity of TERT protein]affects reaction|increases activity 16327978
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased activity of TERT proteinincreases activity 16327978
D014212 Tretinoin Tretinoin results in decreased activity of TERT proteindecreases activity 15770638
16054129
D014212 Tretinoin Tretinoin results in decreased expression of TERT mRNAdecreases expression 16584924
17273765
16482212
15770638
D014212 Tretinoin Tretinoin results in decreased expression of TERT proteindecreases expression 15770638
D014212 Tretinoin [UAB 30 co-treated with Tretinoin] results in decreased expression of TERT mRNAaffects cotreatment|decreases expression 17273765
D014212 Tretinoin Tretinoin results in decreased expression of TERT mRNAdecreases expression 16180984
C012589 trichostatin A trichostatin A affects the expression of TERT mRNAaffects expression 16051188
C012589 trichostatin A trichostatin A affects the expression of TERT proteinaffects expression 16051188
C112106 UAB 30 [UAB 30 co-treated with Tretinoin] results in decreased expression of TERT mRNAaffects cotreatment|decreases expression 17273765
C112106 UAB 30 UAB 30 results in decreased expression of TERT mRNAdecreases expression 17273765
D014520 Urethane Urethane results in increased activity of [TERC protein binds to TEP1 protein binds to TERT protein]affects binding|increases activity 11323394
D014520 Urethane Urethane results in increased expression of TERT mRNAincreases expression 11323394
D015215 Zidovudine Zidovudine results in decreased activity of TERT proteindecreases activity 18097608
16601281
C016837 zinc chloride [Citric Acid co-treated with zinc chloride] results in decreased activity of TERT proteinaffects cotreatment|decreases activity 16624386
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.8814745880
MESH:D000014 Abnormalities, Drug-Induced Isotretinoin 6.5518769834
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.5514514962 15322242 11752688
MESH:D000015 Abnormalities, Multiple Isotretinoin 4.3918769834
MESH:D000038 Abscess Drugs, Chinese Herbal 5.6415043669
MESH:D000138 Acidosis Ammonium Chloride 2.9118287403
MESH:D017486 Acneiform Eruptions Isotretinoin 5.6116232082
MESH:D000152 Acne Vulgaris Isotretinoin 4.8118769834 16185265
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.189612607
MESH:D058186 Acute Kidney Injury Cisplatin 3.3715814532 17670903 12690470
MESH:D055371 Acute Lung Injury Bleomycin 4.2817118201
MESH:D000230 Adenocarcinoma arsenic trioxide 14.2311798837 19825857
MESH:D000230 Adenocarcinoma Cisplatin 14.2317638652 11798837
MESH:D000230 Adenocarcinoma Doxorubicin 14.2317418594
MESH:D000230 Adenocarcinoma Estradiol 14.2311473722
MESH:D000230 Adenocarcinoma Fluorouracil 14.2317638652
MESH:D000230 Adenocarcinoma Urethane 14.2318316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 5.0415814487
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 8.883712494
MESH:D000236 Adenoma Diethylnitrosamine 8.8810737359 6695378
MESH:D000236 Adenoma Urethane 8.8817093202 16926031 6695378 17195641 11497255 10822126 10530776
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 7.8819052882 17620307 19061943 17162532 16434500 18056438
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 7.8816835633
MESH:D011125 Adenomatous Polyposis Coli dibenzoylmethane 5.1417942926
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.0315276417
MESH:D018246 Adrenocortical Adenoma Arsenic 11.5717306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 11.5717306315 16712894
MESH:D000419 Albuminuria Doxorubicin 9.3821441931
MESH:D000419 Albuminuria Raloxifene 9.3817308373 17451421
MESH:D019973 Alcohol-Related Disorders Curcumin 4.4117887948
MESH:D000505 Alopecia Tretinoin 3.0815955085
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 4.9916640825
MESH:D000544 Alzheimer Disease Curcumin 5.6115590663
MESH:D000544 Alzheimer Disease Iron 5.6116563566 16640825
MESH:D000544 Alzheimer Disease Raloxifene 5.6115800139
MESH:D000707 Anaphylaxis mangiferin 4.8316536907 14669257
MESH:D000740 Anemia Drugs, Chinese Herbal 16.5415504547 17963324
MESH:D000740 Anemia Fluorouracil 16.5417963324 16511603 15504547
MESH:D000740 Anemia Iron 16.5416434484 16566752
MESH:D000740 Anemia Tetrachlorodibenzodioxin 16.5411748828
MESH:D000741 Anemia, Aplastic marker/mechanism
MESH:D018798 Anemia, Iron-Deficiency Iron 4.0717162259 16569441 17163184 17147795 17375513
MESH:D000756 Anemia, Sideroblastic Iron 4.2216910769
MESH:D000787 Angina Pectoris Drugs, Chinese Herbal 4.7511477813
MESH:D000860 Anoxia Bleomycin 4.7515782499
MESH:D001004 Anus Diseases Drugs, Chinese Herbal 5.3015043669
MESH:D001145 Arrhythmias, Cardiac Iron 3.8016604332
MESH:D020261 Arsenic Poisoning Arsenic 2.6416251483 18414634 16835338 12569548
MESH:D001169 Arthritis, Experimental Tretinoin 2.6416412693
MESH:D015210 Arthritis, Gouty Drugs, Chinese Herbal 5.0919655406
MESH:D001172 Arthritis, Rheumatoid Curcumin 4.0416807698
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.0416292516
MESH:D001195 Asbestosis Asbestos, Serpentine 5.0410751356
MESH:D001249 Asthma epigallocatechin gallate 4.3816516891
MESH:D001249 Asthma Tretinoin 4.3816456186
MESH:D001260 Ataxia Telangiectasia Iron 4.7915336622
MESH:D050197 Atherosclerosis Arsenic 12.2619371607 12928151
MESH:D050197 Atherosclerosis Curcumin 12.2618704882
MESH:D050197 Atherosclerosis Iron 12.2616632123 16640825
MESH:D050197 Atherosclerosis mangiferin 12.2618450471
MESH:D001284 Atrophy fulvestrant 4.2211514358
MESH:D001321 Autistic Disorder Choline 2.4816818868
MESH:D001321 Autistic Disorder Iron 2.4817352947
MESH:D001321 Autistic Disorder Sirolimus 2.4821115397
MESH:D001327 Autoimmune Diseases Curcumin 8.9819761891
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 8.9819761891
MESH:D001424 Bacterial Infections Iron 4.5416640825
MESH:D001471 Barrett Esophagus Tretinoin 3.7816935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.3511289319 1440618
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 11.9316206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 11.9312125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 11.9316197459 16206674
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.3115746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 9.8414601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 9.8414601052
MESH:D001859 Bone Neoplasms Paclitaxel 3.9615867366
MESH:D001862 Bone Resorption bisphenol A 12.6911985600
MESH:D001862 Bone Resorption Drugs, Chinese Herbal 12.699881647
MESH:D001862 Bone Resorption mangiferin 12.699881647
MESH:D001930 Brain Injuries Raloxifene 3.8316580743
MESH:D002545 Brain Ischemia Curcumin 3.6816770732
MESH:D001932 Brain Neoplasms Curcumin 7.0617596214
MESH:D001932 Brain Neoplasms Doxorubicin 7.0617150277
MESH:D001943 Breast Neoplasms alitretinoin 20.8416344269
MESH:D001943 Breast Neoplasms bisphenol A 20.8417123778
MESH:D001943 Breast Neoplasms Cisplatin 20.8419526202 18382427
MESH:D001943 Breast Neoplasms Curcumin 20.8419250217 18593918 16243823 18462866
MESH:D001943 Breast Neoplasms decitabine 20.8418320071 19208741
MESH:D001943 Breast Neoplasms Diethylnitrosamine 20.8417474063
MESH:D001943 Breast Neoplasms Doxorubicin 20.8416115903 15994142 18628466 15634643 11325840 15668708 17983394 15567936 19526202 15692762 16096432 16826403 15136595 17426702 17369602 16264153 15939500 16595493 18234424 18695136 15993339 16322301 16935488 18382427
MESH:D001943 Breast Neoplasms (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide 20.8415528975
MESH:D001943 Breast Neoplasms Estradiol 20.8416675129 19861407 17261762 17289903 14630087 18497071 12948864 17018787
MESH:D001943 Breast Neoplasms Fluorouracil 20.8416595493 16110121 18608205 15136595 18357371 16557594 19217205
MESH:D001943 Breast Neoplasms fulvestrant 20.8418984771
MESH:D001943 Breast Neoplasms gemcitabine 20.8417039268 18382427
MESH:D001943 Breast Neoplasms letrozole 20.8416002280 17892469
MESH:D001943 Breast Neoplasms Paclitaxel 20.8416115903 16244791 18223236 18323546 11325840 15136595 18234424 16273361
MESH:D001943 Breast Neoplasms Raloxifene 20.8417893378 17261762 15775269 17595753 15572757 17952589 15758505 16912660 17440819 16837676 17242785 17049068
MESH:D001943 Breast Neoplasms Retinoids 20.8419340624 17491551 17368321
MESH:D001943 Breast Neoplasms Tamoxifen 20.8419084267 18425577 19487384 18629630 17261762 15668708 21152245 19155303 16273361 19103187 20390343 17893378 17049068 18815881 21138602 19244106 16873071 15565566 19410462 18351453 19288272 19066611 20859285 19289846 19200415 18855134 17440819 18821012 19011961 19142967 20544844 19189210 18997820 11161223 17242785 20005174 20065188 16202921 19059307 19115204 18984771 16818667 20135344 19221464 19189212
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 20.8420435547
MESH:D001943 Breast Neoplasms Tretinoin 20.8416166294 16443354 16873071
MESH:D001943 Breast Neoplasms UAB 30 20.8416344269 17273765
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.9316813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.7211589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.8116111702
MESH:D002276 Carcinoid Tumor Doxorubicin 10.1316051944
MESH:D002276 Carcinoid Tumor Fluorouracil 10.1316051944
MESH:D002277 Carcinoma Curcumin 10.9018593918
MESH:D002277 Carcinoma Fluorouracil 10.9017121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 10.9016835633
MESH:D002280 Carcinoma, Basal Cell marker/mechanism 19151717
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.1817687452 15504454
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.8619066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.4916168501
MESH:D006528 Carcinoma, Hepatocellular marker/mechanism 16651430
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 28.363581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Arsenic 28.3617306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 28.3616217749 15073043 11135700 15553829 14691202
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 28.3617982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 28.3618691550 17978847 10672840 16540662 20214788 20524982 16681979 19335982 17055752 19394651 16328049 19822196 16502159 20512989 16569478 17761372 16935385 17138121 10737359 20084675 20432363 16830150 19919837 19418558 20514400 19539802 18788625 21159647 19208518 18494052 18056438 19052882 20727157 17428255 18506893 18785209 16878318 17173139 16807293 16288022 3084413 16779866 18971187 19519916 18393292 18210153 18978308 19701751 20101231 3581430 11831363 17162532 19383236 19107877 19171122 20007298 20935162 16698587 18665156
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 28.3618059187 16234567 17876044 16023760
MESH:D006528 Carcinoma, Hepatocellular Estradiol 28.3616924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 28.3616332177 18930000 17088986 17971768 17045692 16799960
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 28.3616313753
MESH:D006528 Carcinoma, Hepatocellular Sirolimus 28.3619335982
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 28.3617306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 28.3616924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 28.361917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.3317123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 4.8412023789 16685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 4.8418414057
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.2019014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 8.717296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 8.711485588 16201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 8.7118695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.5412490120
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 36.9617015178
MESH:D002294 Carcinoma, Squamous Cell Arsenic 36.9617687452 15504454 18922899
MESH:D002294 Carcinoma, Squamous Cell Bleomycin 36.966189445
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 36.966189445 18337622 17066447
MESH:D002294 Carcinoma, Squamous Cell Curcumin 36.9618462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 36.9619215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 36.966189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 36.9618986760 16757204 17066447 16280240
MESH:D002294 Carcinoma, Squamous Cell Isotretinoin 36.9611237771
MESH:D002294 Carcinoma, Squamous Cell Sirolimus 36.9619435901
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 36.9618572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 36.9616096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Arsenic 12.5918640142
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 12.5917572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 12.5917572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 1.9718850075 18670907 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 6.6316278810 17131338 17974986 16364871 17382496 15476868 17924179 16242529 15811867 16651473 16952015 16109756 16612575 17329180 16731534 17308081 16269455 15505089 17928571 17519947 15792986 18627295 16455267 17351982 17007740
MESH:D009202 Cardiomyopathies Iron 6.6316640825
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 5.2617334414 16243910
MESH:D002311 Cardiomyopathy, Dilated Iron 5.2616604332
MESH:D002318 Cardiovascular Diseases abacavir 13.5318753925
MESH:D002318 Cardiovascular Diseases Arsenic 13.5315738583 19152805 17938729
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 13.5316936243
MESH:D002318 Cardiovascular Diseases Raloxifene 13.5315775269
MESH:D002340 Carotid Artery Diseases Arsenic 3.7516973168 18022660
MESH:D002386 Cataract Am 580 6.4717460283
MESH:D002386 Cataract Tretinoin 6.4717460283
MESH:D002418 Cattle Diseases Citric Acid 5.581108409
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 20.217505956
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 20.2118226522
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 20.217505956 21159647 17174075 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 20.2118566989
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 20.2119716837
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 20.2120056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.9316129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.4619052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.4616835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 2.659022650 19486331
MESH:D002822 Choriocarcinoma Tretinoin 4.4916461808
MESH:D019457 Chromosome Breakage Sodium Selenite 4.1115894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 8.0216354765 15668235 8697196 12621046 15340226
MESH:D002972 Cleft Palate Tretinoin 8.029407595
MESH:D002972 Cleft Palate Urethane 8.0212810352
MESH:D003072 Cognition Disorders Raloxifene 3.9815800139
MESH:D003092 Colitis Am 580 17.6717035595
MESH:D003092 Colitis Curcumin 17.6718200517 16782535 16804969
MESH:D003092 Colitis Selenium 17.6717936198
MESH:D003092 Colitis Tretinoin 17.6717035595
MESH:D003103 Coloboma Curcumin 3.9518809619
MESH:D003110 Colonic Neoplasms Curcumin 6.9216340194 19359593
MESH:D003110 Colonic Neoplasms decitabine 6.9217616700
MESH:D003110 Colonic Neoplasms Fluorouracil 6.9217016597 16510598 17172411 17725105 17018589 18772588 17287894 15001691 16340194 17169374
MESH:D003110 Colonic Neoplasms Iron 6.9216640825
MESH:D015179 Colorectal Neoplasms arsenic trioxide 8.9920501625
MESH:D015179 Colorectal Neoplasms Azacitidine 8.9919934284
MESH:D015179 Colorectal Neoplasms Cisplatin 8.9915273666
MESH:D015179 Colorectal Neoplasms decitabine 8.9918981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 8.9918259882 18802399
MESH:D015179 Colorectal Neoplasms Fluorouracil 8.9917094418 17695437 18509181 16282729 14970324 16524972 17255274 18802399 16303861 20501625 15289873 16391804 17016601 15148649 17401013 18448328 17594712 18383874 18949393 16331619 17454858 18288408
MESH:D015179 Colorectal Neoplasms Paclitaxel 8.9918802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.5017141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.2518497527
MESH:D003324 Coronary Artery Disease marker/mechanism
MESH:D023903 Coronary Restenosis arsenic trioxide 3.5612609071
MESH:D003371 Cough Citric Acid 5.539413022
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 6.2110525206
MESH:D019465 Craniofacial Abnormalities Isotretinoin 6.2118769834 9879862
MESH:D019465 Craniofacial Abnormalities Reactive Oxygen Species 6.2115736158
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 6.2115322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 6.2110589399 9125849 8800419 9664655 17551590 9142499 16925845 14991402 9211117 9224671
MESH:D003410 Cri-du-Chat Syndrome marker/mechanism
MESH:D003457 Cryptosporidiosis mangiferin 5.1916547730
MESH:D003490 Cyanosis Endosulfan 4.907900959
MESH:D003550 Cystic Fibrosis Acetylcysteine 3.8119747007
MESH:D007644 Darier Disease Fluorouracil 4.1316733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.4915213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.7219031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.6017474826
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.2111906362 8970840 14531868 11298694 12868966 2524372 18759878 8156756
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 2.893621924 2952479
MESH:D002658 Developmental Disabilities Choline 4.2116818868
MESH:D003920 Diabetes Mellitus Iron 7.6216640825 16604332
MESH:D003920 Diabetes Mellitus Sodium Selenite 7.6216285004
MESH:D003921 Diabetes Mellitus, Experimental mangiferin 4.0512093613 19028559
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.1216506275
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 14.3918403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 14.3920387270
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 14.3916988119
MESH:D003924 Diabetes Mellitus, Type 2 Iron 14.3916506275
MESH:D003924 Diabetes Mellitus, Type 2 mangiferin 14.3911315760 9881663
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 14.3917107852
MESH:D003928 Diabetic Nephropathies Curcumin 22.1718204486
MESH:D003928 Diabetic Nephropathies Estradiol 22.1719279558
MESH:D003928 Diabetic Nephropathies mangiferin 22.1719960420 19706694
MESH:D003928 Diabetic Nephropathies Raloxifene 22.1717308373 15920148 17451421
MESH:D003928 Diabetic Nephropathies Tamoxifen 22.1719279558
MESH:D004342 Drug Hypersensitivity abacavir 4.9215867870 15024131
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 17.7616192314 11289319 6679447 7440962 9328219 6482804 9022650 18692083 1440618 18289764 9653073 8291058 18648102
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 17.7611287661
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 17.7619107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 17.7617416283
MESH:D056486 Drug-Induced Liver Injury Drugs, Chinese Herbal 17.7615027814
MESH:D056486 Drug-Induced Liver Injury Selenium 17.7615131321
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 17.7615131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 17.7620420201
MESH:D004362 Drug Toxicity Cisplatin 15.5115033597 19839026 12231392 12649298
MESH:D004362 Drug Toxicity Doxorubicin 15.5118602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 15.5111462148
MESH:D004362 Drug Toxicity Zidovudine 15.5115040536
MESH:D004381 Duodenal Ulcer Curcumin 3.4317351913
OMIM:127550 DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT, 1 marker/mechanism
MESH:D004417 Dyspnea Endosulfan 4.617900959 3388749
MESH:D004487 Edema Bleomycin 8.3117118201
MESH:D004487 Edema Raloxifene 8.3115860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 8.3112711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.7218230668 16714409 15322242
MESH:D004489 Edema, Cardiac Tretinoin 9.7218230668
MESH:D004646 Emphysema Endosulfan 5.887900959
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 7.1815845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 7.1819031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 11.8019294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 11.8019294695
MESH:D018159 Endolymphatic Hydrops Dimethyl Sulfoxide 5.8920641076
MESH:D016889 Endometrial Neoplasms Doxorubicin 14.0217359293
MESH:D016889 Endometrial Neoplasms Estradiol 14.0218566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 14.0219155303 17893378 16202921 20544844
MESH:D016889 Endometrial Neoplasms Tretinoin 14.0216569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.459294722 10568697
MESH:D004716 Endometritis Citric Acid 6.071108409
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.4918037988
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.4516302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 11.433581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 11.4312903497
MESH:D004938 Esophageal Neoplasms Cisplatin 11.4316481741 15173087 16785472 15464296 17638652
MESH:D004938 Esophageal Neoplasms Fluorouracil 11.4316481741 16337965 15173087 16785472 17638652
MESH:D004938 Esophageal Neoplasms Paclitaxel 11.4316481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.1511564622
MESH:D005124 Eye Abnormalities Tretinoin 7.159664655 16938888
MESH:D015785 Eye Diseases, Hereditary Retinoids 5.3516968212
MESH:D005234 Fatty Liver arsenic trioxide 33.0215073043
MESH:D005234 Fatty Liver Curcumin 33.0219297423
MESH:D005234 Fatty Liver Diethylnitrosamine 33.0220387270 21071580
MESH:D005234 Fatty Liver Iron 33.0216640825
MESH:D005234 Fatty Liver mangiferin 33.0215975614
MESH:D005234 Fatty Liver Raloxifene 33.0217473493
MESH:D005234 Fatty Liver Tamoxifen 33.0214986274 19224547
MESH:D005234 Fatty Liver Zidovudine 33.0218299183
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.8016709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8211858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.356705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.8714745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 9.2619069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 9.2619069698
MESH:D005355 Fibrosis Curcumin 11.1518705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 11.1520067830
MESH:D005355 Fibrosis Tretinoin 11.1517994277
MESH:D005534 Foot Diseases Arsenic 4.896392382
MESH:D005621 Friedreich Ataxia Iron 4.7816604332 16640825
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.6416904648
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.0518462866
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.0216452187
MESH:D005909 Glioblastoma Curcumin 13.2517596214
MESH:D005909 Glioblastoma Doxorubicin 13.2517150277
MESH:D005909 Glioblastoma Tretinoin 13.2517312396
MESH:D005909 Glioblastoma trichostatin A 13.2518801729
MESH:D005910 Glioma marker/mechanism 18021753 19578367
MESH:D005910 Glioma Fluorouracil 2.5716145905
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.437505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9210696789
MESH:D006258 Head and Neck Neoplasms Cisplatin 34.3515102660 15464296
MESH:D006258 Head and Neck Neoplasms Curcumin 34.3518829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 34.3519215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 34.3515692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 34.3518337622 15102660 15162350
MESH:D006258 Head and Neck Neoplasms Retinoids 34.3517368321
MESH:D006258 Head and Neck Neoplasms Sirolimus 34.3519435901
MESH:D006258 Head and Neck Neoplasms Tretinoin 34.3516096774
MESH:D034381 Hearing Loss Cisplatin 8.5319898482
MESH:D034381 Hearing Loss Dimethyl Sulfoxide 8.5320641076
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.4916084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.8715464296
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.2410048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 5.249664655 14991402
MESH:D006331 Heart Diseases Doxorubicin 14.2617875725 17888722 18006777 16244371 12587719 14766674 16707910 16144979 18674790 16330681 16495754 16879835 16244372
MESH:D006331 Heart Diseases mangiferin 14.2612093613
MESH:D006331 Heart Diseases Raloxifene 14.2611110106
MESH:D006331 Heart Diseases Urethane 14.2616046796
MESH:D006333 Heart Failure Doxorubicin 5.7917481944
MESH:D006333 Heart Failure Selenium 5.7917162251
MESH:D006394 Hemangiosarcoma Doxorubicin 3.3115692506
MESH:D006402 Hematologic Diseases Zidovudine 4.1012579204
MESH:D006432 Hemochromatosis Iron 3.9916574947 17053826 17255318 16640825 16604332 17236123
MESH:D006470 Hemorrhage Endosulfan 8.487900959
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 8.4811000095
MESH:D006486 Hemosiderosis Iron 4.5516604332
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 7.606705139
MESH:D006505 Hepatitis Drugs, Chinese Herbal 7.6018339527
MESH:D006525 Hepatitis, Viral, Human Iron 4.8016640825
MESH:D006527 Hepatolenticular Degeneration Iron 4.3017182432
MESH:D006529 Hepatomegaly Iron 6.6416890145
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.6416120746 15340226 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.4017701891
MESH:D006558 Herpes Genitalis Estradiol 4.3615709030
MESH:D006561 Herpes Simplex mangiferin 4.3510715843
MESH:D015658 HIV Infections abacavir 8.9411141242 17457083 12891065
MESH:D015658 HIV Infections Iron 8.9416597321
MESH:D015658 HIV Infections Zidovudine 8.9411141242 11363243 17358032 11698656 20032539
MESH:D006689 Hodgkin Disease Bleomycin 13.0015147373 18501091 17606976
MESH:D006689 Hodgkin Disease Cisplatin 13.0016170182 16200630
MESH:D006689 Hodgkin Disease Doxorubicin 13.0015147373 18501091 17606976
MESH:D006689 Hodgkin Disease sodium arsenite 13.0012676792
MESH:D019584 Hot Flashes Estradiol 3.0917088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.3816959395 18606429 16354765 15340226 8697196
MESH:D006930 Hyperalgesia Tretinoin 2.6916870215
MESH:D006937 Hypercholesterolemia Curcumin 3.4718704882
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.9316778211
MESH:D006946 Hyperinsulinism mangiferin 4.4511315760 9881663
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.8817050553
MESH:D006949 Hyperlipidemias mangiferin 4.2515975614
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.3015034207
MESH:D006967 Hypersensitivity mangiferin 4.1216536907
MESH:D006973 Hypertension Arsenic 6.9216076760 9931084 11953799
MESH:D006973 Hypertension Raloxifene 6.9217577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 6.9218670907 18850075
MESH:D006984 Hypertrophy Sirolimus 4.6419211884
MESH:D006987 Hypesthesia Arsenic 4.8916093927
MESH:D007006 Hypogonadism Iron 3.9216640825
MESH:D007037 Hypothyroidism Iron 4.4416640825
MESH:D054990 Idiopathic Pulmonary Fibrosis marker/mechanism
MESH:D007154 Immune System Diseases mangiferin 5.1916076520
MESH:D007248 Infertility, Male decitabine 12.3617581917
MESH:D007248 Infertility, Male Endosulfan 12.369432128 8588293
MESH:D007248 Infertility, Male fulvestrant 12.3611514358
MESH:D007248 Infertility, Male sodium arsenite 12.3615346721 12646999
MESH:D007249 Inflammation Bleomycin 14.9817118201
MESH:D007249 Inflammation Curcumin 14.9818403477 16956363 17151092
MESH:D007249 Inflammation Diethylnitrosamine 14.9818785209
MESH:D007249 Inflammation mangiferin 14.9815222974
MESH:D007249 Inflammation Tamoxifen 14.9819457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 14.9812878042 12200463
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.9018596194 18200517
MESH:D007251 Influenza, Human Selenium 3.5316624496
MESH:D007333 Insulin Resistance bisphenol A 13.9716393666
MESH:D007333 Insulin Resistance Estradiol 13.9716627594 16393666
MESH:D007333 Insulin Resistance mangiferin 13.9711315760
MESH:D007333 Insulin Resistance Sodium Selenite 13.9714714311
MESH:D007410 Intestinal Diseases Tretinoin 3.1317994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.6410783313
MESH:D002532 Intracranial Aneurysm Reactive Oxygen Species 4.4119381132
MESH:D019189 Iron Metabolism Disorders Iron 4.4317163184
MESH:D007511 Ischemia mangiferin 4.6316806951
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.358074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.9616580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.9617551590 15992940
MESH:D007642 Keratosis Arsenic 4.3316930632 12749816
MESH:D017492 Keratosis, Seborrheic alitretinoin 4.9816144296
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.4715464296
MESH:D007674 Kidney Diseases marker/mechanism 16968891
MESH:D007674 Kidney Diseases Cadmium Chloride 18.5016962696
MESH:D007674 Kidney Diseases Cisplatin 18.5018289764 15190930 12649298 19839026 12231392
MESH:D007674 Kidney Diseases Doxorubicin 18.5015369732 15699352 16775033
MESH:D007674 Kidney Diseases Estradiol 18.5015618244
MESH:D007674 Kidney Diseases mangiferin 18.5012093613
MESH:D007674 Kidney Diseases sodium arsenite 18.5020008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 13.3316707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 13.3316518626
MESH:D007676 Kidney Failure, Chronic Selenium 13.3316518626
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 17.636582329
MESH:D007680 Kidney Neoplasms Estradiol 17.6315610895
MESH:D007680 Kidney Neoplasms Fluorouracil 17.6316985049
MESH:D007680 Kidney Neoplasms Tamoxifen 17.6318625569
MESH:D007680 Kidney Neoplasms Zidovudine 17.6312579204
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.1311231351
MESH:D007859 Learning Disorders Endosulfan 8.328157075
MESH:D007859 Learning Disorders mangiferin 8.3219182383
MESH:D007889 Leiomyoma Curcumin 9.1318555241
MESH:D007889 Leiomyoma Raloxifene 9.1316973256
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 24.0512970779
MESH:D007938 Leukemia arsenic trioxide 24.0515070760
MESH:D007938 Leukemia Azacitidine 24.0519148494
MESH:D007938 Leukemia Curcumin 24.0518462866
MESH:D007938 Leukemia decitabine 24.0519235587 18980019
MESH:D007938 Leukemia SN50 peptide 24.0512970779
MESH:D007938 Leukemia Tretinoin 24.0517143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.4916085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Drugs, Chinese Herbal 3.6115802533
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 12.9012560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 12.9016106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 12.9020370541
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.6516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 7.1314633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive mangiferin 7.1315498116
MESH:D007951 Leukemia, Myeloid arsenic trioxide 23.6719077051
MESH:D007951 Leukemia, Myeloid Azacitidine 23.6719077051
MESH:D007951 Leukemia, Myeloid decitabine 23.6718454857 17236224 19117987
MESH:D007951 Leukemia, Myeloid Retinoids 23.6716482212
MESH:D007951 Leukemia, Myeloid Tretinoin 23.6719285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 12.6017050201 16968895 19850784 16467208 20471514
MESH:D015470 Leukemia, Myeloid, Acute arsenic trisulfide 12.6017708794
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 12.6018720364 17596541
MESH:D015470 Leukemia, Myeloid, Acute decitabine 12.6019387464 17679729 18206229 18704418 19010910 18460780
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 12.6016294345 19850784 17596541
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 12.6018206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.7918055864
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 4.5819299654
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 10.1217339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 10.1211468182 12679006 16330433 17869043 17712046 11161223 19642359 16966277 17649720 19075265 15748426 15622746 9834237 16891316 19035177 15213294 12018890 19225113 15336539 17217047 12712474 17107899 16331271 16112521 16823087
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 10.1219029980 17107899 17506722 17361223 19075265 17217047 16891316 17649720 19225113 17339181 12679006 16140955 17301526 17294898 16935935 16823087 16788101 16331271 16766008 19035177 15748426 17368321 9834237 17712046 19642359
MESH:D015458 Leukemia, T-Cell arsenic trioxide 9.6416882451
MESH:D015458 Leukemia, T-Cell Curcumin 9.6416106398
MESH:D020961 Lewy Body Disease Iron 4.7816563566
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.829224671
MESH:D008064 Lipidoses Tamoxifen 2.6717567588 15342952
MESH:D008080 Liposarcoma Paclitaxel 4.2117353645
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 8.9618522880 18407596 18665156 19638242 20032147
MESH:D008103 Liver Cirrhosis Drugs, Chinese Herbal 8.9617163593
MESH:D008103 Liver Cirrhosis Iron 8.9616640825
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.7515034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 15.5318006644 17355460 18705752
MESH:D008106 Liver Cirrhosis, Experimental Dimethyl Sulfoxide 15.5311682029
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 15.5316439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Drugs, Chinese Herbal 15.5316610055 15641146 15744066 17881167 18606216 15763062 15754396 15849816 18567088 15383259 15339415 17348192 12632512 17666798 15818738 17036385 18371158 18237412 15864749 17629604
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 15.5317481882
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 15.5314716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Sirolimus 15.5317050028
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 15.5318564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 15.5312878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 15.5316248980 18397230
MESH:D008107 Liver Diseases Arsenic 7.6211134558
MESH:D008107 Liver Diseases Curcumin 7.6216956363
MESH:D008107 Liver Diseases Diethylnitrosamine 7.6217034775
MESH:D008107 Liver Diseases Drugs, Chinese Herbal 7.6217207593
MESH:D008108 Liver Diseases, Alcoholic Iron 4.3616737972 17207112
MESH:D008113 Liver Neoplasms Arsenic 27.7116368122
MESH:D008113 Liver Neoplasms arsenic trioxide 27.7114682389
MESH:D008113 Liver Neoplasms Diethylnitrosamine 27.7121278145 19638242 21071580 20434301 18977376 20492335 19642983 19812893 18648771 19551842 18978307 19833225 20118626 19996281 20101389 19255062 19294768 19073162 2862719 2422723 15175105 19256749 19254457 20405173 19426721 20583210 20501860 15885732 19090486 21047994 19427195 21167192 9163691 19690152 18754104 16942905 18644402 12112319 12771043 19850985 19499222 20452335 20137499 10737359
MESH:D008113 Liver Neoplasms Drugs, Chinese Herbal 27.7118339527
MESH:D008113 Liver Neoplasms Fluorouracil 27.7116603448 18383874 15113037 17045692
MESH:D008113 Liver Neoplasms Iron 27.7120302851 16640825
MESH:D008113 Liver Neoplasms sodium arsenite 27.7116712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 27.7116684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 27.7116984957
MESH:D008113 Liver Neoplasms Urethane 27.7117093202 17559639 16391232
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 13.971399818 6587162 598648 3712494
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 13.9720377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.9717854601 16267830 2563599 19519916 16842330 19539802 18079962 17174075 17942915 19004024 3124819 9362446 18282651 19009564 18775883 18164116 18253720 18093689 18544905 21159647 18308698 19126423
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 13.9716842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.9712151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.8415213294
MESH:D008171 Lung Diseases Acetylcysteine 9.9012815614
MESH:D008171 Lung Diseases Asbestos, Serpentine 9.9017200189
MESH:D008171 Lung Diseases sodium arsenite 9.9019095001
MESH:D008175 Lung Neoplasms marker/mechanism 19151717 11323394
MESH:D008175 Lung Neoplasms alitretinoin 45.5416413115
MESH:D008175 Lung Neoplasms Arsenic 45.5417976673 17306315 19168569
MESH:D008175 Lung Neoplasms arsenic trioxide 45.5411798837 19825857
MESH:D008175 Lung Neoplasms Asbestos, Serpentine 45.5411198217
MESH:D008175 Lung Neoplasms Azacitidine 45.5421224363
MESH:D008175 Lung Neoplasms Bleomycin 45.546189445
MESH:D008175 Lung Neoplasms Cisplatin 45.546189445 17225452 11798837
MESH:D008175 Lung Neoplasms Curcumin 45.5418462866 19359593 16243823
MESH:D008175 Lung Neoplasms Diethylnitrosamine 45.546695378 20970405 21163286 20512841
MESH:D008175 Lung Neoplasms Doxorubicin 45.546189445 17418594
MESH:D008175 Lung Neoplasms Drugs, Chinese Herbal 45.5418339527
MESH:D008175 Lung Neoplasms (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide 45.5415528975
MESH:D008175 Lung Neoplasms Fluorouracil 45.5415246190
MESH:D008175 Lung Neoplasms Iron 45.5416640825
MESH:D008175 Lung Neoplasms Isotretinoin 45.5415899809
MESH:D008175 Lung Neoplasms mangiferin 45.5418569708 18520028 18816296
MESH:D008175 Lung Neoplasms sodium arsenite 45.5415276417 16712894 17077188 19931552 17306315
MESH:D008175 Lung Neoplasms Tamoxifen 45.5418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 45.5419555203 11884234
MESH:D008175 Lung Neoplasms Urethane 45.5412765245 10997738 11246140 16391232 10530776 15902970 11062179 12466968 17255336 11544531 11497255 11893704 12117781 10822126 11992545 6695378 15136453 15166089 11074608 12957351 16204055 16289808 16788158 17195641 16007126 16926031 16337739 7750092 11307925 11552296 17093202 14587096 11807781 10779650 11323394
MESH:D008175 Lung Neoplasms Zidovudine 45.5418800350
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.1315086387
MESH:D008223 Lymphoma Curcumin 9.8118462866
MESH:D008223 Lymphoma decitabine 9.8119470736
MESH:D008223 Lymphoma Doxorubicin 9.8116098063
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 3.4514737004
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 7.1517654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 7.1514749477
MESH:D016399 Lymphoma, T-Cell 3-(4-methylphenylsulfonyl)-2-propenenitrile 15.9116173963
MESH:D016399 Lymphoma, T-Cell Curcumin 15.9116173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 15.9115621674
MESH:D008268 Macular Degeneration Iron 3.5816640825
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.1119428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 17.7615458769
MESH:D008325 Mammary Neoplasms, Experimental Drugs, Chinese Herbal 17.7614758024
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 17.7611807958 17203775 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental Selenium 17.7615318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 17.7611731420 19196722 16827153 19196723 14580682
MESH:D008325 Mammary Neoplasms, Experimental UAB 30 17.7614580682
MESH:D020149 Manganese Poisoning Estradiol 10.4219453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.4219453300
MESH:D008415 Mastocytosis Retinoids 5.9316953078
MESH:D008527 Medulloblastoma Tretinoin 2.4817453147
MESH:D008545 Melanoma Bleomycin 33.8315577320
MESH:D008545 Melanoma Cisplatin 33.8318176117 16248763 16432458 17761969 18505091 15577323 12393984 17023156 11135225 12374674 16809738 12883367 18332650
MESH:D008545 Melanoma Curcumin 33.8317885582 18462866
MESH:D008545 Melanoma decitabine 33.8317785578 16505122
MESH:D008545 Melanoma Doxorubicin 33.8316827129
MESH:D008545 Melanoma epigallocatechin gallate 33.8317992120 11746506
MESH:D008545 Melanoma Isotretinoin 33.8317237267
MESH:D008545 Melanoma Paclitaxel 33.8312025231 16342250 12040289
MESH:D008545 Melanoma Reactive Oxygen Species 33.8317992120
MESH:D008545 Melanoma Sirolimus 33.8319282848
MESH:D008545 Melanoma sodium arsenite 33.8316487513 19082730
MESH:D008545 Melanoma Tamoxifen 33.8319393235 12393984
MESH:D008545 Melanoma Tretinoin 33.8316752155
MESH:D008545 Melanoma trichostatin A 33.8316505122
MESH:D018328 Melanoma, Amelanotic Cisplatin 9.3315990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 9.3315990972
MESH:D008569 Memory Disorders Curcumin 7.9617263510
MESH:D008569 Memory Disorders mangiferin 7.9619182383
MESH:D008591 Meningomyelocele Tretinoin 3.7816940565
MESH:D008654 Mesothelioma Cisplatin 8.4417638057
MESH:D008654 Mesothelioma Doxorubicin 8.4417638057
MESH:D008654 Mesothelioma Selenium 8.4415107826
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.1717358032
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.9015792986
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.8815863610
MESH:D009006 Monosomy Azacitidine 5.4119299654
MESH:D009062 Mouth Neoplasms Fluorouracil 7.3618986760 16757204
MESH:D009062 Mouth Neoplasms Sirolimus 7.3619435901
MESH:D052016 Mucositis Doxorubicin 4.1317415656
MESH:D009101 Multiple Myeloma arsenic trioxide 26.5719549372 14977855 11468182 15949261 19417148
MESH:D009101 Multiple Myeloma Azacitidine 26.5718443271 19549372
MESH:D009101 Multiple Myeloma Curcumin 26.5719372569
MESH:D009101 Multiple Myeloma decitabine 26.5718172295
MESH:D009101 Multiple Myeloma Paclitaxel 26.5714749477
MESH:D009101 Multiple Myeloma Raloxifene 26.5716497877
MESH:D009101 Multiple Myeloma trichostatin A 26.5718172295
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 5.0017086897
MESH:D009134 Muscular Atrophy, Spinal Curcumin 10.4617962980
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 10.4617962980
MESH:D009181 Mycoses Iron 4.8016640825
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.0018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 14.2116105982 16882451
MESH:D009190 Myelodysplastic Syndromes Azacitidine 14.2119805378 18720364 17611569 17596541
MESH:D009190 Myelodysplastic Syndromes decitabine 14.2119157545 18608210 19010910 16882708
MESH:D009190 Myelodysplastic Syndromes Tretinoin 14.2117596541
MESH:D009203 Myocardial Infarction abacavir 8.0718753925
MESH:D009203 Myocardial Infarction Doxorubicin 8.0719429709 15857846
MESH:D009203 Myocardial Infarction mangiferin 8.0719172585 17052832 16584858 16538859 16697266
MESH:D017202 Myocardial Ischemia Arsenic 12.2815371236
MESH:D017202 Myocardial Ischemia Iron 12.2816604332
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 12.2812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.0116810080
MESH:D015428 Myocardial Reperfusion Injury Iron 7.0116604332
MESH:D009232 Myxoma Raloxifene 4.8816343187
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 8.2516624393
MESH:D009361 Neoplasm Invasiveness Curcumin 8.2518495463
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 18.393581430
MESH:D009362 Neoplasm Metastasis Acetylcysteine 18.3914720322
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 18.399029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 18.3918259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 18.3915867366
MESH:D009362 Neoplasm Metastasis Tamoxifen 18.3919393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2619410462
MESH:D009369 Neoplasms alitretinoin 18.3616946489
MESH:D009369 Neoplasms Cisplatin 18.3616773208
MESH:D009369 Neoplasms decitabine 18.3619470736 17925555 19116145
MESH:D009369 Neoplasms Fluorouracil 18.3618600527 18239605 16928823
MESH:D009369 Neoplasms sodium arsenite 18.3611559025
MESH:D009369 Neoplasms Tretinoin 18.3616594593 16946489
MESH:D009369 Neoplasms Urethane 18.3615625555
MESH:D009374 Neoplasms, Experimental Asbestos, Serpentine 11.8611704859
MESH:D009374 Neoplasms, Experimental sodium arsenite 11.8620056578
MESH:D009374 Neoplasms, Experimental Urethane 11.8615582191
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 8.6212497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 8.6219196722 19200415 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 3.0817289903
MESH:D009395 Nephritis, Interstitial Cisplatin 3.8315464296
MESH:D009401 Nephrosis Doxorubicin 4.1316899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 7.8815640375 16889571
MESH:D009404 Nephrotic Syndrome Iron 7.8817178036
MESH:D009410 Nerve Degeneration mangiferin 4.1017433543
MESH:D009421 Nervous System Malformations bisphenol A 18.3316427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 18.3316427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 18.3314600291
MESH:D009421 Nervous System Malformations Tretinoin 18.339125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.9618462866
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 22.486679447
MESH:D009436 Neural Tube Defects Acetylcysteine 22.4819446573
MESH:D009436 Neural Tube Defects Arsenic 22.4816620997
MESH:D009436 Neural Tube Defects arsenic trioxide 22.4810525206
MESH:D009436 Neural Tube Defects sodium arsenite 22.4812854658
MESH:D009436 Neural Tube Defects Tretinoin 22.489142499
MESH:D009447 Neuroblastoma Cisplatin 9.388761367
MESH:D009447 Neuroblastoma Doxorubicin 9.3815555623
MESH:D009447 Neuroblastoma Isotretinoin 9.3817368321
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 6.8820387270
MESH:D019636 Neurodegenerative Diseases Iron 6.8817296847 16604332
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.048761367
MESH:D020078 Neurogenic Inflammation Arsenic 3.7717056641
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.4520387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 2.9716436463
MESH:D009765 Obesity Curcumin 2.5519297423
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 2.854026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.353988306
MESH:D010003 Osteoarthritis Iron 3.5416640825
MESH:D010014 Osteolysis Paclitaxel 4.3215867366
MESH:D010024 Osteoporosis Curcumin 9.5018719352
MESH:D010024 Osteoporosis Iron 9.5016640825 16648989
MESH:D010024 Osteoporosis Raloxifene 9.5017882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Drugs, Chinese Herbal 8.4616548355
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 8.4615579764 15758505 17893378 17823083
MESH:D012516 Osteosarcoma Doxorubicin 3.5815930896
MESH:D010049 Ovarian Diseases bisphenol A 4.3311985600
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 42.4616211241
MESH:D010051 Ovarian Neoplasms Arsenic 42.4617306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 42.4616624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Cisplatin 42.466897625 17225452 19769630 15464296
MESH:D010051 Ovarian Neoplasms Curcumin 42.4619020741 18462866
MESH:D010051 Ovarian Neoplasms decitabine 42.4619259094 19331143
MESH:D010051 Ovarian Neoplasms (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide 42.4615528975
MESH:D010051 Ovarian Neoplasms Estradiol 42.4619401270
MESH:D010051 Ovarian Neoplasms Paclitaxel 42.4611161223
MESH:D010051 Ovarian Neoplasms sodium arsenite 42.4615276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 42.4616936753
MESH:D010051 Ovarian Neoplasms trichostatin A 42.4619331143
MESH:D010051 Ovarian Neoplasms Urethane 42.4616391232
MESH:D010146 Pain Tretinoin 2.3916870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 32.3715580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 32.3719003803
MESH:D010190 Pancreatic Neoplasms Curcumin 32.3717440100 19401701 19196508
MESH:D010190 Pancreatic Neoplasms decitabine 32.3719294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 32.3716540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 32.3716500647 16929163 15113037 19003803
MESH:D010190 Pancreatic Neoplasms gemcitabine 32.3711504793 18383843 16929163 18992248 17440100
MESH:D010190 Pancreatic Neoplasms Reactive Oxygen Species 32.3715580305
MESH:D010190 Pancreatic Neoplasms Tretinoin 32.3715976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 32.3719294695
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 11.977296757
MESH:D010212 Papilloma Hydrogen Peroxide 11.9712065085
MESH:D010212 Papilloma Iron 11.9712065085
MESH:D010235 Paraganglioma arsenic trioxide 3.5519927285
MESH:D020447 Parasomnias Iron 5.3517352947
MESH:D010300 Parkinson Disease Iron 7.3216563566 16640825
MESH:D010300 Parkinson Disease mangiferin 7.3217433543
MESH:D010300 Parkinson Disease Sirolimus 7.3219682553
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.5812520081
MESH:D010518 Periodontitis mangiferin 4.9319026997
MESH:D010523 Peripheral Nervous System Diseases Arsenic 7.9916093927
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 7.9915464296
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.3315371236 16905509 6392382
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.806228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.4917983394
MESH:D010900 Pituitary Diseases Iron 5.0016604332
MESH:D010911 Pituitary Neoplasms Urethane 4.7716391232
MESH:D010954 Plasmacytoma Selenium 4.2215087411
MESH:D010995 Pleural Diseases Asbestos, Serpentine 5.0510923243
MESH:D010997 Pleural Neoplasms Cisplatin 11.7117638057
MESH:D010997 Pleural Neoplasms Doxorubicin 11.7117638057
MESH:D011014 Pneumonia Bleomycin 4.7518024389 16317386 17071938
MESH:D011041 Poisoning Iron 3.6916604332
MESH:D017499 Porokeratosis alitretinoin 5.3316144296
MESH:D017119 Porphyria Cutanea Tarda Iron 8.9516640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 8.9518163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 2.992563599
MESH:D011225 Pre-Eclampsia Iron 3.9016640825
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 12.6110548101
MESH:D011297 Prenatal Exposure Delayed Effects Isotretinoin 12.6118769834
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 12.6111399792 11222880 11896295 11118676
MESH:D055728 Primary Myelofibrosis decitabine 10.2917616702
MESH:D055728 Primary Myelofibrosis trichostatin A 10.2917616702
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 8.5820887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 8.5820887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 19151717
MESH:D011471 Prostatic Neoplasms Arsenic 7.9216140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 7.9219131511
MESH:D011471 Prostatic Neoplasms Azacitidine 7.9218324645
MESH:D011471 Prostatic Neoplasms bicalutamide 7.9217914592 18487222 19011039 15638997 19240160
MESH:D011471 Prostatic Neoplasms bisphenol A 7.9216740699
MESH:D011471 Prostatic Neoplasms Curcumin 7.9218769126 10851300 11398177 18156803 18226269 12497104 15129424
MESH:D011471 Prostatic Neoplasms Doxorubicin 7.9216729912 18437689 16888761 15897917 16868541 15749863
MESH:D011471 Prostatic Neoplasms Estradiol 7.9216740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 7.9218626508 19082440
MESH:D011471 Prostatic Neoplasms Paclitaxel 7.9217136230 16356831 16729912 17172428
MESH:D011471 Prostatic Neoplasms Raloxifene 7.9216536755 15731164 16220300
MESH:D011471 Prostatic Neoplasms Retinoids 7.9216724957 16166285
MESH:D011471 Prostatic Neoplasms sodium arsenite 7.9216039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 7.9218760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 7.9215067354
MESH:D011471 Prostatic Neoplasms trichostatin A 7.9219789329 18798265
MESH:D011507 Proteinuria Arsenic 7.2721343184
MESH:D011507 Proteinuria Tretinoin 7.2716636307
MESH:D011528 Protozoan Infections Iron 5.3516640825
MESH:D011596 Psychomotor Disorders Isotretinoin 5.2618769834
MESH:D011625 Pterygium Tretinoin 4.1316723453
MESH:D011629 Puberty, Precocious bisphenol A 4.1310548101
MESH:D011645 Puerperal Infection Citric Acid 6.071108409
MESH:D011654 Pulmonary Edema Bleomycin 4.6515808516
MESH:D011656 Pulmonary Emphysema Curcumin 3.9519168576
MESH:D011658 Pulmonary Fibrosis Asbestos, Serpentine 7.9315511213 18569384
MESH:D011658 Pulmonary Fibrosis Bleomycin 7.9318008008 15322207 18162602 17434272 12624602 17241526 12574379 11554783 16314464 14609568 15541506 17177178 16115399 21435439
MESH:D011658 Pulmonary Fibrosis Drugs, Chinese Herbal 7.9316987627
MESH:D011693 Purpura Raloxifene 4.8815770314
MESH:D011833 Radiation Injuries, Experimental mangiferin 5.7415830843
MESH:D012003 Rectal Fistula Drugs, Chinese Herbal 5.3015043669
MESH:D012004 Rectal Neoplasms Fluorouracil 3.4518286688 18722050 15538739 16160472
MESH:D051437 Renal Insufficiency Cisplatin 8.2615464296
MESH:D051437 Renal Insufficiency Doxorubicin 8.2617922066
MESH:D015427 Reperfusion Injury marker/mechanism 16968891
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 7.4812210543
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 7.4810666014 18379247
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2118990726
MESH:D012148 Restless Legs Syndrome Iron 4.0416930377
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 2.873692021
MESH:D012175 Retinoblastoma SN50 peptide 5.8412466137
MESH:D012208 Rhabdomyosarcoma decitabine 8.9219155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 8.9216283617 16116481
MESH:D012221 Rhinitis, Allergic, Perennial Drugs, Chinese Herbal 4.6115015336
MESH:D012509 Sarcoma Curcumin 7.6618462866
MESH:D012509 Sarcoma Doxorubicin 7.6616767912 15675481 17710206 17203757 15625365 18313854
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 13.6816646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 13.6814601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 13.6814601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.1317846226
MESH:D012640 Seizures Endosulfan 3.6210698677 7539098
MESH:D018805 Sepsis Curcumin 3.5318389075
MESH:D012772 Shock, Septic mangiferin 4.5815177305
MESH:D012871 Skin Diseases Arsenic 4.6416353154 16759981 15952646 6392382 17050553 16702368 18709164 19834688 17938729 17453740 17548696
MESH:D012871 Skin Diseases monomethylarsonous acid 4.6417431481
MESH:D012878 Skin Neoplasms Arsenic 34.3217029826 19538983 15504454 16251483 17976673 17050553
MESH:D012878 Skin Neoplasms Doxorubicin 34.3215692506
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 34.3212065085
MESH:D012878 Skin Neoplasms Iron 34.3212065085
MESH:D012878 Skin Neoplasms Retinoids 34.3217538947
MESH:D012878 Skin Neoplasms sodium arsenite 34.3218572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 34.328532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 34.3216192470
MESH:D012878 Skin Neoplasms Tretinoin 34.3216467112
MESH:D012878 Skin Neoplasms Urethane 34.3211807781
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.6715464296
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.9317203757 16767912 15625365
MESH:D013088 Spermatocele Tamoxifen 3.6216709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.3819457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.2712854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 12.9317007042
MESH:D013274 Stomach Neoplasms Cisplatin 12.9317522103 15958060 18396642
MESH:D013274 Stomach Neoplasms decitabine 12.9319037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 12.9318456281
MESH:D013274 Stomach Neoplasms Drugs, Chinese Herbal 12.9318339527
MESH:D013274 Stomach Neoplasms Fluorouracil 12.9318567086 19084572 18396642 16951190 16424979 17522103 17172411 15786421 19015929 17498489
MESH:D013274 Stomach Neoplasms Paclitaxel 12.9318506536 18396642
MESH:D013274 Stomach Neoplasms Tretinoin 12.9317261132
MESH:D013274 Stomach Neoplasms Zidovudine 12.9317696246
MESH:D013276 Stomach Ulcer Acetylcysteine 8.9917918041
MESH:D013276 Stomach Ulcer Curcumin 8.9916631530 19188055
MESH:D013276 Stomach Ulcer mangiferin 8.9917918041
MESH:D020521 Stroke Raloxifene 3.2916837676
MESH:D013345 Subarachnoid Hemorrhage Drugs, Chinese Herbal 5.0917634840
MESH:D019966 Substance-Related Disorders bisphenol A 3.3316045194 16684133
MESH:D013398 Sudden Infant Death Iron 4.7916640825
MESH:D024801 Tauopathies Paclitaxel 4.1616930453
MESH:D013736 Testicular Neoplasms Cisplatin 4.0215464296 17225452
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2312697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 25.946582329 3712494 1399818 6587162 7505956
MESH:D013964 Thyroid Neoplasms arsenic trioxide 25.9419014326
MESH:D013964 Thyroid Neoplasms decitabine 25.9417967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 25.947505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 25.9416010429 17909728
MESH:D013964 Thyroid Neoplasms Retinoids 25.9416940797
MESH:D013964 Thyroid Neoplasms Tretinoin 25.9417045167 16026305
MESH:D013978 Tibial Fractures Estradiol 11.4919048282
MESH:D013978 Tibial Fractures Raloxifene 11.4919048282
MESH:D014062 Tongue Neoplasms Fluorouracil 7.9116280240
MESH:D014062 Tongue Neoplasms Tretinoin 7.9116051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.3115213294
MESH:D014235 Trichinellosis mangiferin 5.3914669257
MESH:D014376 Tuberculosis Iron 6.7116597321
MESH:D014376 Tuberculosis Tretinoin 6.7116040207
MESH:D014402 Tuberous Sclerosis Sirolimus 4.9421115397 18495876
MESH:D001749 Urinary Bladder Neoplasms marker/mechanism 19151717
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 34.908074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 34.9018640142 19322015 19429237 11144890 15987713 17306315 17976673
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 34.9011780464 20435036 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 34.9017225452 15464296 12973940
MESH:D001749 Urinary Bladder Neoplasms Curcumin 34.9018593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 34.9019087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 34.9017653716
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 34.9020375083
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 34.9017572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 34.9011723127 16452187 16712894 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 34.908653321 17572228 16712894
MESH:D014565 Urogenital Neoplasms Curcumin 4.6118462866
MESH:D002583 Uterine Cervical Neoplasms marker/mechanism 19151717
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 17.9316803524
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 17.9316803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 17.9311813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 17.9316129372
MESH:D014591 Uterine Diseases bisphenol A 4.3414652134
MESH:D014604 Uveal Neoplasms decitabine 10.6017785578
MESH:D014604 Uveal Neoplasms Tretinoin 10.6016752155
MESH:D014605 Uveitis Sirolimus 4.961336536
MESH:D014625 Vaginal Neoplasms Cisplatin 9.0715577323
MESH:D014625 Vaginal Neoplasms Zidovudine 9.0712579204
MESH:D014652 Vascular Diseases Arsenic 9.6717056641
MESH:D014652 Vascular Diseases sodium arsenite 9.6717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9212125929
MESH:D019043 Vascular Neoplasms Urethane 5.2410620525
MESH:D054556 Venous Thromboembolism Raloxifene 4.5416837676
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.5817638931 17334414 17678736 16364871
MESH:D014820 Vitiligo Tretinoin 3.4316761959
MESH:D014839 Vomiting Cisplatin 4.0511897121
MESH:D014846 Vulvar Neoplasms Raloxifene 4.8816343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.5815886252
MESH:D015431 Weight Loss Bleomycin 4.9912624602
MESH:D009396 Wilms Tumor Tretinoin 3.4016287080
MESH:D014947 Wounds and Injuries Drugs, Chinese Herbal 4.0016313111
Pathway ID Pathway Name
REACT:22172 Chromosome Maintenance
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36447
    • No data
    Releated disease ID Related disease Name
    PA445468Pulmonary Fibrosis
    PA445468Pulmonary Fibrosis
    PA446872Dyskeratosis Congenita
    Releated drug ID Related drug Name
    PA451581tamoxifen
    PA164768822chlorotrianisene
    PA164754789conjugated estrogens
    PA164745534dienestrol
    PA449307diethylstilbestrol
    PA449503estradiol
    PA449509estrogens
    PA449512estrone
    PA449527ethinyl estradiol
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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