Annotation Detail for TFAP2B
Basic Information
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| Gene Symbol: | TFAP2B ( AP-2B,AP2-B,MGC21381 ) |
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| Gene Full Name: | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
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| Band: | 6p12.3 |
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| Quick Links | Entrez ID:7021; OMIM: 601601; Uniprot ID:AP2B_HUMAN; ENSEMBL ID: ENSG00000008196; HGNC ID: 11743 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Desease Name |
|---|
| personality traits |
| PSYCH |
| anxiety disorder |
| METABOLIC |
| adiposity |
| REPRODUCTION |
| diabetes, type 2 |
| patent ductus arteriosus |
| Insulin Resistance |
| Desease Name |
|---|
| Body mass index |
| Adiposity |
| Desease Name |
|---|
| Char syndrome |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D008345 |
Manganese |
Manganese results in increased expression of TFAP2B mRNA | increases expression | 17175027
|
| C025340 |
manganese chloride |
manganese chloride results in increased expression of TFAP2B mRNA | increases expression | 17175027
|
| C025462 |
sulindac sulfide |
sulindac sulfide results in increased expression of TFAP2B mRNA | increases expression | 16184548
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000544 |
Alzheimer Disease |
|
sulindac sulfide |
3.16 | 18759972 |
| MESH:D000756 |
Anemia, Sideroblastic |
|
Manganese |
12.69 | 16910769 |
| MESH:D000756 |
Anemia, Sideroblastic |
|
manganese chloride |
12.69 | 16910769 |
| MESH:D002289 |
Carcinoma, Non-Small-Cell Lung |
|
sulindac sulfide |
3.56 | 12391285 |
| MESH:C538076 |
Char syndrome |
marker/mechanism |
|
| 10802654 |
| MESH:D019465 |
Craniofacial Abnormalities |
marker/mechanism |
|
| 10802654 |
| MESH:D005909 |
Glioblastoma |
|
Manganese |
4.18 | 17043766 |
| MESH:D006228 |
Hand Deformities, Congenital |
marker/mechanism |
|
| 10802654 |
| MESH:D020149 |
Manganese Poisoning |
|
Manganese |
6.39 | 16568477 16551646 19453300 |
| MESH:D009069 |
Movement Disorders |
|
Manganese |
5.54 | 16551646 |
| MESH:D009410 |
Nerve Degeneration |
|
Manganese |
4.62 | 16551646 |
| MESH:D010300 |
Parkinson Disease |
|
Manganese |
3.50 | 11181820 |
| MESH:D020734 |
Parkinsonian Disorders |
|
Manganese |
4.92 | 16140633 |
| MESH:D014594 |
Uterine Neoplasms |
|
sulindac sulfide |
5.24 | 18645019 |
Related Pathway Information