AutismKB 2.0

Annotation Detail for TFAP4


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Gene Symbol:TFAP4 ( AP-4,bHLHc41 )
Gene Full Name: transcription factor AP-4 (activating enhancer binding protein 4)
Band: 16p13.3
Quick LinksEntrez ID:7023; OMIM: 600743; Uniprot ID:TFAP4_HUMAN; ENSEMBL ID: ENSG00000090447; HGNC ID: 11745
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C017947 sodium arsenite sodium arsenite results in decreased expression of TFAP4 mRNAdecreases expression 12679051
C017947 sodium arsenite sodium arsenite results in increased expression of TFAP4 mRNAincreases expression 17879257
C021751 tanshinone tanshinone results in decreased expression of TFAP4 mRNAdecreases expression 15849732
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.7715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.9716712894 17306315
MESH:D001943 Breast Neoplasms tanshinone 3.5819885617 15849732
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 2.0116507464 17306315 15276417
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.4818572023
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 3.3119524636 20056578
MESH:D005833 Genital Neoplasms, Female sodium arsenite 5.5716452187
MESH:D005910 Glioma tanshinone 4.1716955220
MESH:D006689 Hodgkin Disease sodium arsenite 3.6212676792
MESH:D017379 Hypertrophy, Left Ventricular tanshinone 5.7419662366
MESH:D007248 Infertility, Male sodium arsenite 3.2915346721 12646999
MESH:D007674 Kidney Diseases sodium arsenite 3.0420008137
MESH:D008113 Liver Neoplasms sodium arsenite 2.5115276417 16712894
MESH:D008171 Lung Diseases sodium arsenite 3.4819095001
MESH:D008175 Lung Neoplasms sodium arsenite 1.9016712894 19931552 17077188 17306315 15276417
MESH:D008545 Melanoma sodium arsenite 2.0819082730 16487513
MESH:D009369 Neoplasms sodium arsenite 2.6911559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 4.4320056578
MESH:D009436 Neural Tube Defects sodium arsenite 3.4412854658
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.5417306315 15276417
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.2316039940
MESH:D012878 Skin Neoplasms sodium arsenite 2.8819524636 18572023
MESH:D016135 Spinal Dysraphism sodium arsenite 4.1812854658
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 2.6516452187 11723127 16712894 17306315
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 4.2711813266
MESH:D014652 Vascular Diseases sodium arsenite 5.3117056641
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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