AutismKB 2.0

Annotation Detail for NR2F1


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Basic Information Top
Gene Symbol:NR2F1 ( COUP-TFI,EAR-3,EAR3,ERBAL3,NR2F2,SVP44,TCFCOUP1,TFCOUP1 )
Gene Full Name: nuclear receptor subfamily 2, group F, member 1
Band: 5q15
Quick LinksEntrez ID:7025; OMIM: 132890; Uniprot ID:COT1_HUMAN; ENSEMBL ID: ENSG00000175745; HGNC ID: 7975
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
Gene Expression
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C038864 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of NR2F1 mRNAincreases expression 15583048
D000082 Acetaminophen Acetaminophen affects the expression of NR2F1 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of NR2F1 mRNAaffects expression 16483693
D016718 Arachidonic Acid Arachidonic Acid results in decreased expression of NR2F1 mRNAdecreases expression 16704987
D001104 Arbutin Arbutin results in increased expression of NR2F1 mRNAincreases expression 17103032
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NR2F1 mRNAdecreases expression 19150397
D002713 Chlorine [Ozone co-treated with Chlorine] results in increased expression of NR2F1 mRNAaffects cotreatment|increases expression 18636392
C039671 ciglitazone NR2F1 protein promotes the reaction [[SR 11237 co-treated with ciglitazone] results in increased expression of RARB protein]affects cotreatment|increases expression|increases reaction 12839938
D016572 Cyclosporine Cyclosporine results in decreased expression of NR2F1 mRNAdecreases expression 20106945
C014347 decitabine decitabine results in decreased expression of NR2F1 mRNAdecreases expression 19363521
C014347 decitabine TP53 protein affects the reaction [decitabine results in decreased expression of NR2F1 mRNA]affects reaction|decreases expression 19363521
D003907 Dexamethasone Dexamethasone results in increased expression of NR2F1 mRNAincreases expression 19022236
D002117 Calcitriol Calcitriol results in increased expression of NR2F1 mRNAincreases expression 16002434
D000431 Ethanol Ethanol results in decreased expression of NR2F1 mRNAdecreases expression 15353170
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of NR2F1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of NR2F1 mRNAdecreases expression 17557909
15576828
D005632 Fructose Fructose affects the reaction [NR2F1 protein binds to SHBG promoter]affects binding|affects reaction 17992261
D005947 Glucose Glucose affects the reaction [NR2F1 protein binds to SHBG promoter]affects binding|affects reaction 17992261
C030110 oxaliplatin oxaliplatin results in increased expression of NR2F1 mRNAincreases expression 17762391
D010126 Ozone [Ozone co-treated with Chlorine] results in increased expression of NR2F1 mRNAaffects cotreatment|increases expression 18636392
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of NR2F1 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of NR2F1 mRNAincreases expression 12832660
C017947 sodium arsenite sodium arsenite results in decreased expression of NR2F1 mRNAdecreases expression 16014739
C087130 SR 11237 NR2F1 protein promotes the reaction [[SR 11237 co-treated with ciglitazone] results in increased expression of RARB protein]affects cotreatment|increases expression|increases reaction 12839938
D013974 Thyroxine Thyroxine affects the expression of NR2F1 mRNAaffects expression 17403546
D014212 Tretinoin Tretinoin results in increased expression of NR2F1 mRNAincreases expression 15977162
C034613 triacsin C triacsin C results in decreased expression of NR2F1 mRNAdecreases expression 16704987
D014810 Vitamin E Vitamin E results in increased expression of NR2F1 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 3.7318926900 17676605
MESH:D000138 Acidosis Ammonium Chloride 9.8318287403
MESH:D000138 Acidosis Ethanol 9.8311192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7517505938
MESH:D055371 Acute Lung Injury Chlorine 8.5520601635
MESH:D055371 Acute Lung Injury pirinixic acid 8.5518653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.7714692618
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.2916434500
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.5115276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.7116712894 17306315
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.1315451040 15451039
MESH:D000505 Alopecia Tretinoin 3.4615955085
MESH:D000544 Alzheimer Disease Ozone 2.4015513908
MESH:D000799 Angioedema Acetaminophen 3.6510982225
MESH:D000853 Anophthalmos Ethanol 4.6315513904
MESH:D001008 Anxiety Disorders Ethanol 3.8511141031
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2811256880
MESH:D001169 Arthritis, Experimental Dexamethasone 11.6017659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 11.6015885639
MESH:D001169 Arthritis, Experimental Tretinoin 11.6016412693
MESH:D001172 Arthritis, Rheumatoid Ozone 4.5115570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.5116292516
MESH:D001249 Asthma Ozone 4.7616373670 17854713
MESH:D001249 Asthma Tretinoin 4.7616456186
MESH:D001321 Autistic Disorder Acetaminophen 2.2318445737
MESH:D001321 Autistic Disorder Arachidonic Acid 2.2318582451
MESH:D001471 Barrett Esophagus Tretinoin 4.2216935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.4019483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 8.4016197459 16206674
MESH:D001943 Breast Neoplasms marker/mechanism 11850205
MESH:D001943 Breast Neoplasms Calcitriol 2.0011237771
MESH:D001943 Breast Neoplasms decitabine 2.0019208741 18320071
MESH:D001943 Breast Neoplasms Tretinoin 2.0016873071 16443354 16166294
MESH:D016535 Bronchial Hyperreactivity Ozone 3.5314754758 18417511 16777450 15516495 17626835 18315731 19059883
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.4016813970
MESH:D002056 Burns Ethanol 4.4616374292
MESH:D002100 Cachexia Ozone 4.5516183385
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.7416050911
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.9716168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.333084413
MESH:D006528 Carcinoma, Hepatocellular Ethanol 6.3315763234 18788625 15289165
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 6.3317306315 16507464 15276417
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 6.331917145
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 10.3611237771
MESH:D002294 Carcinoma, Squamous Cell decitabine 10.3619215824
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 10.3618572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 10.3616096774 16051514
MESH:D006332 Cardiomegaly Ethanol 7.1419332462
MESH:D006332 Cardiomegaly Thyroxine 7.1418093424
MESH:D002386 Cataract Acetaminophen 6.8610977129
MESH:D002386 Cataract Tretinoin 6.8617460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.4120889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.4112371664
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 10.4120056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.4016129372
MESH:D002779 Cholestasis Cyclosporine 12.5319486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.5316105132 17333356 17681005 15861022 16919318 17110522 11677210
MESH:D002779 Cholestasis pirinixic acid 12.5319176532
MESH:D002822 Choriocarcinoma Tretinoin 4.9716461808
MESH:D002971 Cleft Lip Ethanol 3.4915513904
MESH:D002972 Cleft Palate Ethanol 5.8915513904
MESH:D002972 Cleft Palate Tretinoin 5.899407595
MESH:D003092 Colitis Tretinoin 3.5217035595
MESH:D003110 Colonic Neoplasms decitabine 5.8217616700
MESH:D003110 Colonic Neoplasms Dexamethasone 5.8215824018
MESH:D003110 Colonic Neoplasms oxaliplatin 5.8216024531 16510598 16004971
MESH:D015179 Colorectal Neoplasms decitabine 2.9318981723
MESH:D015179 Colorectal Neoplasms oxaliplatin 2.9317594712 17695437 18448328 17255274 17401013 18509181
MESH:D003327 Coronary Disease Fructose 4.3518504504
MESH:D019465 Craniofacial Abnormalities Dexamethasone 5.2917728286
MESH:D019465 Craniofacial Abnormalities Ethanol 5.2915451040 15451039 11198716 19302082 10194807 11873399 15513904
MESH:D019465 Craniofacial Abnormalities Tretinoin 5.2916925845 9142499 10589399 9224671 17551590 8800419 9211117 9125849 9664655 14991402
MESH:D019465 Craniofacial Abnormalities Vitamin E 5.2919769572
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 3.2212438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3418249437
MESH:D003921 Diabetes Mellitus, Experimental Fructose 4.3418603373
MESH:D003924 Diabetes Mellitus, Type 2 Fructose 3.3318603373
MESH:D003967 Diarrhea Dexamethasone 3.527237001
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.7714725611 19420014 16177239 10774834 11739529 19370779 12705907 15619225 11529661 2444490 12958197 16109766 11743745 17562736 19739265 19923254 19416960 12153990 11421492 10663392 10915739 19085960 11287661 19164858 17906064 18713872 12540782 16485898 16781746 12594235 11834606 16081117 14550746 15968718 17522070 12392966 18071297 16393943 11461765 16227642 14986274
MESH:D056486 Drug-Induced Liver Injury Ethanol 3.7711566570
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9119426721
MESH:D004417 Dyspnea Chlorine 4.4320016425
MESH:C538011 Eales disease Vitamin E 4.519068938
MESH:D004485 Eczema Dexamethasone 4.2812438553
MESH:D004487 Edema Arachidonic Acid 10.677990266 16716910 9599246 9831321 15177302 11698051
MESH:D004487 Edema Dexamethasone 10.6719703484
MESH:D004487 Edema pirinixic acid 10.6712083418
MESH:D004489 Edema, Cardiac Tretinoin 4.2718230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 14.5415138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental ciglitazone 14.5416844232
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 14.5412538720
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.9219294695
MESH:D016889 Endometrial Neoplasms Tretinoin 2.9816569247
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.4620426865
MESH:D004938 Esophageal Neoplasms Ethanol 4.4616704527
MESH:D005124 Eye Abnormalities Tretinoin 3.449664655 16938888
MESH:D005234 Fatty Liver Cyclosporine 22.8219224547
MESH:D005234 Fatty Liver Ethanol 22.8219236843 16409862 18620774
MESH:D005234 Fatty Liver Ethinyl Estradiol 22.8215345470
MESH:D005234 Fatty Liver Fructose 22.8219196556 18641190 18395287
MESH:D005234 Fatty Liver pirinixic acid 22.8220131406 19236843
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.4717920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.1116946407 15513904 15451040 10194807
MESH:D005334 Fever Arachidonic Acid 4.4911852909
MESH:D005355 Fibrosis Cyclosporine 13.8512639820 12168785
MESH:D005355 Fibrosis Fructose 13.8518504504
MESH:D005355 Fibrosis Tretinoin 13.8517994277
MESH:D005739 Gas Poisoning Chlorine 4.8220016425
MESH:D005756 Gastritis Acetaminophen 10.4816983495
MESH:D005756 Gastritis Ethanol 10.4815046732
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.4916452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.038708960
MESH:D005909 Glioblastoma Tretinoin 2.8817312396
MESH:D018149 Glucose Intolerance Fructose 5.1419165636
MESH:D006258 Head and Neck Neoplasms decitabine 7.4119215824
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.4116096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.9716084493
MESH:D006330 Heart Defects, Congenital Tretinoin 6.4514991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 6.4516080930
MESH:D006333 Heart Failure pirinixic acid 2.4220558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2315720958
MESH:D006529 Hepatomegaly pirinixic acid 2.8116221962 18467677 19772884 19176532
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 5.757520565
MESH:D006548 Hernia, Diaphragmatic Vitamin E 5.7516863852 16490937
MESH:D006689 Hodgkin Disease sodium arsenite 3.0012676792
MESH:D019584 Hot Flashes Vitamin E 3.7814716179
MESH:D006930 Hyperalgesia Acetaminophen 17.4716870215
MESH:D006930 Hyperalgesia Ethanol 17.4718783367
MESH:D006930 Hyperalgesia oxaliplatin 17.4717418472
MESH:D006930 Hyperalgesia Tretinoin 17.4716870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.3816778211
MESH:D006943 Hyperglycemia pirinixic acid 3.0220558911
MESH:D006946 Hyperinsulinism Fructose 4.7414757778 18360027 19008412 18563319 15752949
MESH:D006949 Hyperlipidemias Fructose 4.5715752949
MESH:D006973 Hypertension Cyclosporine 8.4010903974
MESH:D006973 Hypertension Dexamethasone 8.4017042910
MESH:D006973 Hypertension Fructose 8.4014568997 19008412 16843071 14633139 14573337
MESH:D015228 Hypertriglyceridemia Fructose 4.9119342510 19799862
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6216569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2812013081
MESH:D007248 Infertility, Male decitabine 10.5017581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.5017937319
MESH:D007248 Infertility, Male sodium arsenite 10.5015346721 12646999
MESH:D007249 Inflammation Arachidonic Acid 5.3715177302 17371808 9831321
MESH:D007249 Inflammation Dexamethasone 5.378960868 11099482
MESH:D007251 Influenza, Human Vitamin E 4.0216624496
MESH:D007333 Insulin Resistance Fructose 7.2519586609 14757778 18563319 19799862 18981581 19008412 18057795 14573337 17133782 19342510 14633139
MESH:D007333 Insulin Resistance pirinixic acid 7.2516306350
MESH:D007410 Intestinal Diseases Tretinoin 3.5817994277
MESH:D007569 Jaw Abnormalities Ethanol 9.7515513904
MESH:D007569 Jaw Abnormalities Tretinoin 9.7517551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2515604871
MESH:D007674 Kidney Diseases Acetaminophen 13.5315629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 13.5318776723 10903974 8314463
MESH:D007674 Kidney Diseases sodium arsenite 13.5320008137
MESH:D007674 Kidney Diseases Vitamin E 13.5312488133
MESH:D007680 Kidney Neoplasms Cyclosporine 2.5812371664
MESH:D007859 Learning Disorders Ethanol 4.0215451040
MESH:D007938 Leukemia decitabine 6.1219235587 18980019
MESH:D007938 Leukemia Tretinoin 6.1217143497
MESH:D007951 Leukemia, Myeloid decitabine 8.9918454857 19117987 17236224
MESH:D007951 Leukemia, Myeloid Tretinoin 8.9919285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute decitabine 3.8518460780 18704418 19010910 18206229 17679729 19387464
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.8519850784 16294345 17596541
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.2718055864
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.0319035177 16140955 19075265 16331271 16891316 17107899 19029980 17217047 17649720 17368321 19642359 17339181 17294898 17301526 17506722 16935935 9834237 16766008 12679006 15748426 16788101 17712046 19225113 16823087 17361223
MESH:D017880 Limb Deformities, Congenital Ethanol 7.8717676605
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.879224671
MESH:D008103 Liver Cirrhosis Ethanol 3.2715289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.9018295389
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 6.4916718785
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 6.4918166357
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.4915474484
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.4916248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 6.4916169303
MESH:D008107 Liver Diseases Acetaminophen 1.5912969438 16611625 19014921 11587558 19460945 16610002 19784758 12587719
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.4617347304 17207112
MESH:D017114 Liver Failure, Acute Acetaminophen 3.0717185352 16871587
MESH:D008113 Liver Neoplasms pirinixic acid 4.2515890375 20007298 16377806
MESH:D008113 Liver Neoplasms sodium arsenite 4.2515276417 16712894
MESH:D008171 Lung Diseases Ozone 11.6319066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 11.6319095001
MESH:D008171 Lung Diseases Vitamin E 11.6316863852
MESH:D055370 Lung Injury Ozone 3.6620417186
MESH:D008175 Lung Neoplasms ciglitazone 6.3915899809
MESH:D008175 Lung Neoplasms Dexamethasone 6.3911195469 15824018
MESH:D008175 Lung Neoplasms Ozone 6.397614698 8597069
MESH:D008175 Lung Neoplasms sodium arsenite 6.3917306315 15276417 16712894 19931552 17077188
MESH:D008175 Lung Neoplasms Vitamin E 6.3911062179
MESH:D008223 Lymphoma decitabine 3.2819470736
MESH:D008527 Medulloblastoma Tretinoin 2.7117453147
MESH:D008545 Melanoma decitabine 7.0716505122 17785578
MESH:D008545 Melanoma Glucose 7.0714993021
MESH:D008545 Melanoma sodium arsenite 7.0719082730 16487513
MESH:D008545 Melanoma Tretinoin 7.0716752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3819513568
MESH:D008569 Memory Disorders Ethanol 4.0018411066 15451040
MESH:D008591 Meningomyelocele Tretinoin 4.2416940565
MESH:D024821 Metabolic Syndrome X Fructose 4.6617261469 19165636 18497449 17098227 16815490
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5916801185
MESH:D008679 Metaplasia Ozone 4.9110496685
MESH:D009101 Multiple Myeloma decitabine 7.0818172295
MESH:D009101 Multiple Myeloma Dexamethasone 7.0815867202 15744524 16118317
MESH:D009135 Muscular Diseases pirinixic acid 3.3216239165
MESH:D009190 Myelodysplastic Syndromes decitabine 11.7718608210 19157545 19010910 16882708
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 11.779809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 11.7717596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.0719151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8016411023
MESH:D009369 Neoplasms decitabine 11.0919116145 19470736 17925555
MESH:D009369 Neoplasms pirinixic acid 11.0917405874
MESH:D009369 Neoplasms sodium arsenite 11.0911559025
MESH:D009369 Neoplasms Tretinoin 11.0916594593 16946489
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.4820056578
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1218481113 19348381
MESH:D009421 Nervous System Malformations Tretinoin 3.599125849
MESH:D009436 Neural Tube Defects sodium arsenite 6.9012854658
MESH:D009436 Neural Tube Defects Tretinoin 6.909142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.7218514411
MESH:D009765 Obesity Fructose 4.6917707055 18585860
MESH:D009765 Obesity pirinixic acid 4.6920558911
MESH:D010051 Ovarian Neoplasms decitabine 7.5819331143 19259094
MESH:D010051 Ovarian Neoplasms sodium arsenite 7.5815276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 7.5816936753
MESH:D010146 Pain Acetaminophen 6.0816870215
MESH:D010146 Pain Tretinoin 6.0816870215
MESH:D010190 Pancreatic Neoplasms decitabine 8.3219294695
MESH:D010190 Pancreatic Neoplasms Ethanol 8.3212384795
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.3215976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5111578682
MESH:D010538 Peritonitis Ozone 3.9416369182
MESH:D011014 Pneumonia Ozone 4.2018381685 18007984 18929643
MESH:D011230 Precancerous Conditions Cyclosporine 3.0612371664
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.4421297632
MESH:D055728 Primary Myelofibrosis decitabine 4.5417616702
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.5915572423
MESH:D011471 Prostatic Neoplasms Calcitriol 2.6918247401 12479363 16289102 16644109 15754350
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.6916039940
MESH:D011471 Prostatic Neoplasms Vitamin E 2.6915084515
MESH:D011507 Proteinuria Tretinoin 3.4316636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.1215861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1616882103
MESH:D011625 Pterygium Tretinoin 4.6016723453
MESH:D015427 Reperfusion Injury pirinixic acid 2.2919058328
MESH:D012120 Respiration Disorders Chlorine 5.0218579056
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.8411700416 18379247
MESH:D012208 Rhabdomyosarcoma decitabine 10.3519155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 10.3516116481 16283617
MESH:D012640 Seizures Ethanol 3.059754883
MESH:D012871 Skin Diseases Vitamin E 2.3918709164
MESH:D012878 Skin Neoplasms Glucose 9.1414993021
MESH:D012878 Skin Neoplasms sodium arsenite 9.1418572023 19524636
MESH:D012878 Skin Neoplasms Tretinoin 9.1416467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7516709447
MESH:D016135 Spinal Dysraphism sodium arsenite 3.6512854658
MESH:D013272 Stomach Diseases Dexamethasone 4.1315472012
MESH:D013274 Stomach Neoplasms decitabine 3.3719037991
MESH:D013274 Stomach Neoplasms Ethanol 3.3718456281
MESH:D013274 Stomach Neoplasms Tretinoin 3.3717261132
MESH:D013276 Stomach Ulcer Dexamethasone 6.9815138204
MESH:D013276 Stomach Ulcer Ethanol 6.9817918041 17189318 11906479 9211565 9562338 16755016
MESH:D020521 Stroke Vitamin E 3.3716517955
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.099754883
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9915669648
MESH:D013959 Thyroid Diseases Thyroxine 5.4519910387
MESH:D013964 Thyroid Neoplasms decitabine 6.8217967635
MESH:D013964 Thyroid Neoplasms Tretinoin 6.8217045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 3.6216051514
MESH:D014376 Tuberculosis Tretinoin 3.1116040207
MESH:D001749 Urinary Bladder Neoplasms decitabine 5.0019087683 17616700
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 5.0011723127 17306315 16452187 16712894
MESH:D014581 Urticaria Acetaminophen 2.8010982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.8511813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.8516129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1214692618
MESH:D014604 Uveal Neoplasms decitabine 12.1817785578
MESH:D014604 Uveal Neoplasms Tretinoin 12.1816752155
MESH:D014605 Uveitis Cyclosporine 11.121336536
MESH:D014605 Uveitis Dexamethasone 11.121336536
MESH:D014652 Vascular Diseases sodium arsenite 4.2317056641
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3714671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.8716761959
MESH:D009396 Wilms Tumor Tretinoin 3.8116287080
MESH:D014985 Xerophthalmia Cyclosporine 4.2517120751
Pathway ID Pathway Name
REACT:71 Gene Expression
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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