AutismKB 2.0

Annotation Detail for THRA


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:THRA ( AR7,EAR7,ERB-T-1,ERBA,ERBA1,MGC000261,MGC43240,NR1A1,THRA1,THRA2,c-ERBA-1 )
Gene Full Name: thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
Band: 17q21.1
Quick LinksEntrez ID:7067; OMIM: 190120; Uniprot ID:THA_HUMAN; ENSEMBL ID: ENSG00000126351; HGNC ID: 11796
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04080Neuroactive ligand-receptor interaction
Pathway IDPathway Name
Gene Expression
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C010642 3,3',5-triiodothyroacetic acid 3,3',5-triiodothyroacetic acid binds to and results in increased activity of THRA proteinaffects binding|increases activity 17532181
C010642 3,3',5-triiodothyroacetic acid MED1 protein promotes the reaction [3,3',5-triiodothyroacetic acid results in increased activity of THRA protein]increases activity|increases reaction 16324150
C065775 4,4'-diiodobiphenyl 4,4'-diiodobiphenyl binds to and results in increased activity of THRA proteinaffects binding|increases activity 15585367
D000082 Acetaminophen Acetaminophen affects the expression of THRA mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in decreased expression of THRA mRNAdecreases expression 15976192
D000638 Amiodarone Amiodarone binds to THRA proteinaffects binding 11806713
D000638 Amiodarone Amiodarone results in decreased expression of THRA mRNA alternative formdecreases expression 10445678
D000638 Amiodarone Amiodarone results in decreased expression of THRA mRNA alternative formdecreases expression 17535870
7598731
D000638 Amiodarone Amiodarone results in increased expression of THRA mRNA alternative formincreases expression 17535870
D000638 Amiodarone [Isoproterenol co-treated with Amiodarone] results in increased expression of THRA mRNA alternative formaffects cotreatment|increases expression 7598731
D000643 Ammonium Chloride Ammonium Chloride affects the expression of THRA mRNAaffects expression 16483693
C006780 bisphenol A bisphenol A inhibits the reaction [Triiodothyronine results in increased activity of THRA protein]decreases reaction|increases activity 12414890
C006780 bisphenol A bisphenol A results in increased expression of THRA mRNAincreases expression 16902998
C006780 bisphenol A bisphenol A inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
C006780 bisphenol A bisphenol A inhibits the reaction [Triiodothyronine results in increased expression of THRA mRNA]decreases reaction|increases expression 16905155
C006780 bisphenol A bisphenol A results in decreased expression of THRA mRNAdecreases expression 16905155
C066859 Bobel 24 Bobel 24 binds to and results in increased activity of THRA proteinaffects binding|increases activity 17532181
C066859 Bobel 24 Bobel 24 inhibits the reaction [Triiodothyronine binds to and results in increased activity of THRA protein]affects binding|decreases reaction|increases activity 17532181
C032036 bromobenzene bromobenzene results in decreased expression of THRA mRNAdecreases expression 15976192
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of THRA mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of THRA mRNAdecreases expression 15976192
C039671 ciglitazone ciglitazone results in decreased activity of THRA proteindecreases activity 16023420
D003024 Clozapine Clozapine results in decreased expression of THRA mRNA alternative formdecreases expression 11564422
D003024 Clozapine Clozapine results in increased expression of THRA mRNA alternative formincreases expression 11564422
C030123 coumarin coumarin results in increased expression of THRA mRNAincreases expression 18480146
C036116 desethylamiodarone desethylamiodarone binds to THRA proteinaffects binding 7589780
C036116 desethylamiodarone desethylamiodarone inhibits the reaction [Triiodothyronine binds to THRA protein]affects binding|decreases reaction 7589780
C036116 desethylamiodarone desethylamiodarone inhibits the reaction [Triiodothyronine binds to THRA protein alternative form]affects binding|decreases reaction 12538616
D003993 Dibutyl Phthalate Dibutyl Phthalate promotes the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]increases expression|increases reaction 15590988
D003633 Dichlorodiphenyl Dichloroethylene Dichlorodiphenyl Dichloroethylene affects the expression of THRA mRNAaffects expression 17056472
D003633 Dichlorodiphenyl Dichloroethylene Dichlorodiphenyl Dichloroethylene results in increased expression of THRA mRNAincreases expression 16764480
D004010 Dicofol Dicofol inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
D004054 Diethylstilbestrol Diethylstilbestrol inhibits the reaction [Triiodothyronine metabolite binds to THRA protein]affects binding|decreases reaction 15590988
D004128 Dimethylnitrosamine Dimethylnitrosamine results in decreased expression of THRA mRNAdecreases expression 15976192
C118667 dronedarone dronedarone binds to and results in decreased activity of THRA protein alternative formaffects binding|decreases activity 12538616
C118667 dronedarone dronedarone inhibits the reaction [Triiodothyronine binds to THRA protein alternative form]affects binding|decreases reaction 12538616
C118667 dronedarone dronedarone metabolite binds to and results in decreased activity of THRA protein alternative formaffects binding|decreases activity 12538616
C118667 dronedarone dronedarone metabolite inhibits the reaction [Triiodothyronine binds to THRA protein alternative form]affects binding|decreases reaction 12538616
C118667 dronedarone dronedarone results in decreased expression of THRA mRNA alternative formdecreases expression 17535870
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of THRA mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of THRA mRNAdecreases expression 17222921
D004997 Ethinyl Estradiol Ethinyl Estradiol inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
D005419 Flavonoids Flavonoids results in increased expression of THRA mRNAincreases expression 18035473
D005485 Flutamide Flutamide results in decreased expression of THRA mRNAdecreases expression 17222921
D006220 Haloperidol Haloperidol results in decreased expression of THRA mRNA alternative formdecreases expression 11564422
D006220 Haloperidol Haloperidol results in increased expression of THRA mRNA alternative formincreases expression 11564422
C089796 hexabromocyclododecane hexabromocyclododecane binds to and results in increased activity of THRA proteinaffects binding|increases activity 15585367
D007455 Iodine Iodine results in increased expression of THRA mRNAincreases expression 17555094
D007455 Iodine Selenium inhibits the reaction [Iodine results in increased expression of THRA mRNA]decreases reaction|increases expression 17555094
C008161 ioxynil ioxynil inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
D007545 Isoproterenol [Isoproterenol co-treated with Amiodarone] results in increased expression of THRA mRNA alternative formaffects cotreatment|increases expression 7598731
D007545 Isoproterenol Isoproterenol results in increased expression of THRA mRNA alternative formincreases expression 7598731
C446946 KB 130015 KB 130015 inhibits the reaction [Triiodothyronine binds to and results in increased activity of THRA protein]affects binding|decreases reaction|increases activity 11806713
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased activity of THRA proteindecreases activity 12388159
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of THRA mRNAdecreases expression 12057914
16847310
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of THRA proteindecreases expression 12388159
D008713 Methimazole Methimazole results in decreased expression of THRA mRNAdecreases expression 16289343
C005219 methyl cellosolve methyl cellosolve results in increased expression of THRA mRNAincreases expression 19643169
D015735 Mifepristone Mifepristone results in decreased expression of THRA mRNAdecreases expression 17584828
C008542 monodansylcadaverine monodansylcadaverine inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
C007350 nitrofen nitrofen binds to and results in increased activity of THRA proteinaffects binding|increases activity 15585367
C007350 nitrofen nitrofen results in decreased expression of THRA mRNAdecreases expression 11685700
D010416 Pentachlorophenol Pentachlorophenol inhibits the reaction [Triiodothyronine binds to and results in increased activity of THRA protein]affects binding|decreases reaction|increases activity 17532181
C494474 perchlorate perchlorate results in increased expression of THRA mRNAincreases expression 16289343
D010656 Phenylephrine Phenylephrine results in increased expression of THRA proteinincreases expression 17389455
D010656 Phenylephrine THRA protein affects the reaction [Phenylephrine results in decreased expression of MYH6 protein]affects reaction|decreases expression 11577024
D010693 Phloretin Phloretin inhibits the reaction [Triiodothyronine metabolite binds to THRA protein]affects binding|decreases reaction 15590988
D010693 Phloretin Phloretin inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
C006253 pirinixic acid pirinixic acid results in decreased expression of THRA mRNAdecreases expression 16985257
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls binds to and results in increased activity of THRA proteinaffects binding|increases activity 17532181
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls results in increased expression of THRA mRNAincreases expression 16835054
D012643 Selenium Selenium inhibits the reaction [Iodine results in increased expression of THRA mRNA]decreases reaction|increases expression 17555094
C017947 sodium arsenite sodium arsenite results in increased expression of THRA mRNAincreases expression 17451858
D013448 Sulfobromophthalein Sulfobromophthalein inhibits the reaction [Triiodothyronine metabolite binds to THRA protein]affects binding|decreases reaction 15590988
D013448 Sulfobromophthalein Sulfobromophthalein inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
D014284 Triiodothyronine Bobel 24 inhibits the reaction [Triiodothyronine binds to and results in increased activity of THRA protein]affects binding|decreases reaction|increases activity 17532181
D014284 Triiodothyronine Pentachlorophenol inhibits the reaction [Triiodothyronine binds to and results in increased activity of THRA protein]affects binding|decreases reaction|increases activity 17532181
D014284 Triiodothyronine tetrabromobisphenol A inhibits the reaction [Triiodothyronine binds to and results in increased activity of THRA protein]affects binding|decreases reaction|increases activity 17532181
D014284 Triiodothyronine tetrachlorodian inhibits the reaction [Triiodothyronine binds to and results in increased activity of THRA protein]affects binding|decreases reaction|increases activity 17532181
D014284 Triiodothyronine Triiodothyronine binds to and results in increased activity of THRA proteinaffects binding|increases activity 17532181
D014284 Triiodothyronine desethylamiodarone inhibits the reaction [Triiodothyronine binds to THRA protein]affects binding|decreases reaction 7589780
D014284 Triiodothyronine desethylamiodarone inhibits the reaction [Triiodothyronine binds to THRA protein alternative form]affects binding|decreases reaction 12538616
D014284 Triiodothyronine dronedarone inhibits the reaction [Triiodothyronine binds to THRA protein alternative form]affects binding|decreases reaction 12538616
D014284 Triiodothyronine dronedarone metabolite inhibits the reaction [Triiodothyronine binds to THRA protein alternative form]affects binding|decreases reaction 12538616
D014284 Triiodothyronine Triiodothyronine binds to THRA proteinaffects binding 7589780
D014284 Triiodothyronine Triiodothyronine binds to THRA protein alternative formaffects binding 12538616
D014284 Triiodothyronine bisphenol A inhibits the reaction [Triiodothyronine results in increased activity of THRA protein]decreases reaction|increases activity 12414890
D014284 Triiodothyronine KB 130015 inhibits the reaction [Triiodothyronine binds to and results in increased activity of THRA protein]affects binding|decreases reaction|increases activity 11806713
D014284 Triiodothyronine tetrabromobisphenol A inhibits the reaction [Triiodothyronine results in increased activity of THRA protein]decreases reaction|increases activity 15680168
D014284 Triiodothyronine tetrachlorodian inhibits the reaction [Triiodothyronine results in increased activity of THRA protein]decreases reaction|increases activity 15680168
D014284 Triiodothyronine Triiodothyronine binds to and results in increased activity of THRA proteinaffects binding|increases activity 11806713
D014284 Triiodothyronine Triiodothyronine inhibits the reaction [THRA protein results in increased expression of SOD1 mRNA]decreases reaction|increases expression 16738222
D014284 Triiodothyronine Triiodothyronine results in increased activity of THRA proteinincreases activity 15680168
12414890
D014284 Triiodothyronine Triiodothyronine results in increased expression of THRA proteinincreases expression 16021636
D014284 Triiodothyronine tetrabromobisphenol A promotes the reaction [Triiodothyronine results in increased expression of THRA mRNA]increases expression|increases reaction 16678281
D014284 Triiodothyronine Triiodothyronine results in increased expression of THRA mRNAincreases expression 16678281
D014284 Triiodothyronine bisphenol A inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
D014284 Triiodothyronine Dibutyl Phthalate promotes the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]increases expression|increases reaction 15590988
D014284 Triiodothyronine Dicofol inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
D014284 Triiodothyronine Diethylstilbestrol inhibits the reaction [Triiodothyronine metabolite binds to THRA protein]affects binding|decreases reaction 15590988
D014284 Triiodothyronine Ethinyl Estradiol inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
D014284 Triiodothyronine ioxynil inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
D014284 Triiodothyronine monodansylcadaverine inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
D014284 Triiodothyronine Phloretin inhibits the reaction [Triiodothyronine metabolite binds to THRA protein]affects binding|decreases reaction 15590988
D014284 Triiodothyronine Phloretin inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
D014284 Triiodothyronine Sulfobromophthalein inhibits the reaction [Triiodothyronine metabolite binds to THRA protein]affects binding|decreases reaction 15590988
D014284 Triiodothyronine Sulfobromophthalein inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA]decreases reaction|increases expression 15590988
D014284 Triiodothyronine Triiodothyronine metabolite results in increased expression of THRA mRNAincreases expression 15590988
D014284 Triiodothyronine Triiodothyronine results in increased activity of THRA proteinincreases activity 16023420
D014284 Triiodothyronine Triiodothyronine results in increased expression of THRA mRNAincreases expression 15708448
D014284 Triiodothyronine Triiodothyronine results in increased expression of THRA proteinincreases expression 16021636
D014284 Triiodothyronine bisphenol A inhibits the reaction [Triiodothyronine results in increased expression of THRA mRNA]decreases reaction|increases expression 16905155
D014284 Triiodothyronine Triiodothyronine results in increased expression of THRA mRNAincreases expression 16905155
16289343
D013974 Thyroxine Thyroxine results in increased expression of THRA mRNAincreases expression 16764480
D013974 Thyroxine Thyroxine results in increased expression of THRA mRNAincreases expression 16289343
D013629 Tamoxifen Tamoxifen affects the expression of THRA mRNAaffects expression 17555576
C020806 tetrabromobisphenol A tetrabromobisphenol A binds to and results in increased activity of THRA proteinaffects binding|increases activity 17532181
C020806 tetrabromobisphenol A tetrabromobisphenol A inhibits the reaction [Triiodothyronine binds to and results in increased activity of THRA protein]affects binding|decreases reaction|increases activity 17532181
C020806 tetrabromobisphenol A tetrabromobisphenol A inhibits the reaction [Triiodothyronine results in increased activity of THRA protein]decreases reaction|increases activity 15680168
C020806 tetrabromobisphenol A tetrabromobisphenol A promotes the reaction [Triiodothyronine results in increased expression of THRA mRNA]increases expression|increases reaction 16678281
C020806 tetrabromobisphenol A tetrabromobisphenol A results in increased expression of THRA mRNAincreases expression 16678281
C041181 tetrachlorodian tetrachlorodian binds to and results in increased activity of THRA proteinaffects binding|increases activity 17532181
C041181 tetrachlorodian tetrachlorodian inhibits the reaction [Triiodothyronine binds to and results in increased activity of THRA protein]affects binding|decreases reaction|increases activity 17532181
C041181 tetrachlorodian tetrachlorodian inhibits the reaction [Triiodothyronine results in increased activity of THRA protein]decreases reaction|increases activity 15680168
D013853 Thioacetamide Thioacetamide results in decreased expression of THRA mRNAdecreases expression 15976192
C057693 troglitazone troglitazone results in decreased activity of THRA proteindecreases activity 16023420
C025643 vinclozolin vinclozolin affects the expression of THRA mRNAaffects expression 19015723
D015054 Zymosan Zymosan results in decreased expression of THRA mRNAdecreases expression 16847310
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.9914745880
MESH:D000014 Abnormalities, Drug-Induced methyl cellosolve 4.076499812 6474471 3652986
MESH:D000138 Acidosis Ammonium Chloride 3.0118287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.3817505938
MESH:D055371 Acute Lung Injury Lipopolysaccharides 7.3711850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 7.3718653653
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 3.9416033868
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 3.9414692618
MESH:D000236 Adenoma Dimethylnitrosamine 3.2219555203
MESH:D018248 Adenoma, Liver Cell pirinixic acid 2.9416434500
MESH:D000310 Adrenal Gland Neoplasms Pentachlorophenol 11.4410696769
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 11.4415276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.3416712894 17306315
MESH:D000380 Agranulocytosis Clozapine 4.5212649775 16160616 14617031
MESH:D000382 Agricultural Workers' Diseases Dichlorodiphenyl Dichloroethylene 7.9516487989
MESH:D000382 Agricultural Workers' Diseases Dicofol 7.9512584743
MESH:D000686 Amyloidosis Diethylstilbestrol 3.9615469931
MESH:D000740 Anemia Zymosan 4.0818664788
MESH:D000748 Anemia, Macrocytic methyl cellosolve 5.793699323
MESH:D000799 Angioedema Acetaminophen 3.2910982225
MESH:D001008 Anxiety Disorders vinclozolin 3.2019015723
MESH:D001145 Arrhythmias, Cardiac Amiodarone 12.5418057881 18218290 20041841
MESH:D001145 Arrhythmias, Cardiac dronedarone 12.5418651412
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 12.5417460149
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.9311256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.4015885639
MESH:D001169 Arthritis, Experimental Zymosan 6.4016872482 15944321 15188379 17659584 15142272
MESH:D053627 Asthenozoospermia methyl cellosolve 4.983987992
MESH:D001281 Atrial Fibrillation Amiodarone 8.8218651412 19698954
MESH:D001281 Atrial Fibrillation dronedarone 8.8217804843
MESH:D001284 Atrophy methyl cellosolve 4.672626667 3699323 6705890
MESH:D001321 Autistic Disorder Acetaminophen 2.1318445737
MESH:D001321 Autistic Disorder Haloperidol 2.1319368416 18080171
MESH:D001778 Blood Coagulation Disorders Amiodarone 12.6319483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 12.6319483382
MESH:D001778 Blood Coagulation Disorders Thioacetamide 12.6319483382
MESH:D001862 Bone Resorption bisphenol A 3.3711985600
MESH:D001919 Bradycardia Isoproterenol 9.146740701
MESH:D001919 Bradycardia Phenylephrine 9.1415306635
MESH:D001932 Brain Neoplasms monodansylcadaverine 5.3616170020
MESH:D001943 Breast Neoplasms bisphenol A 1.9717123778
MESH:D001943 Breast Neoplasms Dichlorodiphenyl Dichloroethylene 1.9715061365
MESH:D001943 Breast Neoplasms Diethylstilbestrol 1.9715324884 17129689
MESH:D001943 Breast Neoplasms Tamoxifen 1.9715565566 18855134 18815881 16202921 19487384 17242785 16873071 16273361 21138602 19103187 17049068 19142967 20544844 19066611 19410462 16818667 19115204 18425577 17440819 19189210 17893378 20135344 19288272 20005174 19200415 18629630 17261762 18821012 19221464 11161223 20859285 19155303 19289846 19244106 20390343 19084267 21152245 19011961 20065188 18984771 18351453 15668708 19059307 18997820 19189212
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.2516050911 15700767 3786805 15721981 16192424 16011737 10355542 16097048 16124888 15673190 16227642 18705752
MESH:D002277 Carcinoma Dimethylnitrosamine 3.5919555203
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.9719066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 9.873084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 9.8718788625
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 9.8716924424 15948411
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 9.8717306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 9.8716924424
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 9.8717997003
MESH:D002278 Carcinoma in Situ bisphenol A 4.4417123778
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 4.3016033868
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.3018572023
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.1417572228
MESH:D006332 Cardiomegaly Isoproterenol 9.9311179087 7544033
MESH:D006332 Cardiomegaly Phenylephrine 9.9317124262 17287366 11754973 11179087 15728586 16170337
MESH:D006332 Cardiomegaly Thyroxine 9.9318093424
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.6819225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.5418974383
MESH:D002375 Catalepsy Haloperidol 4.361977408 15215559
MESH:D002386 Cataract Acetaminophen 2.2410977129
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 2.6120056578 19524636
MESH:D018281 Cholangiocarcinoma Thioacetamide 3.8218291259
MESH:D002764 Cholecystitis methyl cellosolve 5.246499794
MESH:D002779 Cholestasis Ethinyl Estradiol 6.3717681005 17110522 15861022 11677210 16105132 17333356 16919318
MESH:D002779 Cholestasis pirinixic acid 6.3719176532
MESH:D003072 Cognition Disorders Clozapine 4.4317123785
MESH:D003092 Colitis Selenium 3.2517936198
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 2.7215531428
MESH:D000013 Congenital Abnormalities methyl cellosolve 4.3512530607 6499821
MESH:D019465 Craniofacial Abnormalities nitrofen 3.1211405365
MESH:D003456 Cryptorchidism Dibutyl Phthalate 16.3516037377
MESH:D003456 Cryptorchidism Diethylstilbestrol 16.3516002989 12952375
MESH:D003456 Cryptorchidism vinclozolin 16.3514966744
MESH:D016757 Death, Sudden, Cardiac Haloperidol 4.3420210726
MESH:D003704 Dementia Haloperidol 8.7011575062
MESH:D003704 Dementia Polychlorinated Biphenyls 8.7016140633
MESH:D003711 Demyelinating Diseases Tamoxifen 3.8319031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1518249437
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 6.5716402076
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 6.5719647726
MESH:D003924 Diabetes Mellitus, Type 2 troglitazone 6.5716023994
MESH:D003925 Diabetic Angiopathies troglitazone 5.1012601628
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.0219279558
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.0015331141
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 18.7317906064 11461765 11743745 17562736 11739529 19370779 10663392 16109766 14550746 19164858 18713872 16485898 12705907 16781746 10774834 16227642 12540782 17522070 11529661 11834606 18071297 19923254 12153990 14986274 19739265 11287661 19416960 14725611 10915739 19085960 15619225 15968718 19420014 12958197 16393943 12392966 16177239 12594235 2444490 16081117 11421492
MESH:D056486 Drug-Induced Liver Injury Amiodarone 18.7318218290 15265979
MESH:D056486 Drug-Induced Liver Injury bromobenzene 18.7312628495 10092053
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 18.7315968718 16177239 16227642 3732212 10915739 11566570 2869522 6623471 6884620 19336974 17522070 3786805 10092053 19085960 15027814 15998439 21278145 7120509 4309450 7440962 7179309 9327722
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 18.738172417
MESH:D056486 Drug-Induced Liver Injury Selenium 18.7315131321
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 18.7312963478
MESH:D056486 Drug-Induced Liver Injury troglitazone 18.7314986274
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.5419426721
MESH:D050171 Dyslipidemias Clozapine 3.7816402076
MESH:D004417 Dyspnea Dichlorodiphenyl Dichloroethylene 4.7116487989
MESH:D004487 Edema pirinixic acid 5.5412083418
MESH:D004487 Edema Zymosan 5.547907874
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental ciglitazone 12.5516844232
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 12.5512538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 12.5519031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.1516402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 6.3315700306 16804899
MESH:D016889 Endometrial Neoplasms Tamoxifen 6.3317893378 16202921 20544844 19155303
MESH:D004715 Endometriosis Mifepristone 3.8916134523
MESH:D019446 Endotoxemia Lipopolysaccharides 3.8515821434 15328337 17637181
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 2.7517016578
MESH:D005218 Fat Necrosis Thioacetamide 5.1616456712
MESH:D005234 Fatty Liver Amiodarone 19.4814986274
MESH:D005234 Fatty Liver Carbon Tetrachloride 19.4816239168 19224547 17595544 15959796 61145 12795759 16045604 12631006
MESH:D005234 Fatty Liver Ethinyl Estradiol 19.4815345470
MESH:D005234 Fatty Liver pirinixic acid 19.4819236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 19.4819224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.0416513791 16611131 15751030 16002989 16534752
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.0416709447
MESH:D005327 Fetal Resorption methyl cellosolve 4.996474471 3987992 6499821 6499812
MESH:D020567 Fetal Weight methyl cellosolve 5.246499821 6499812 6474471
MESH:D005334 Fever Lipopolysaccharides 3.549205823 11852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.9814745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.6419069698
MESH:D005355 Fibrosis Carbon Tetrachloride 2.9318705752
MESH:D005532 Foot Deformities, Congenital methyl cellosolve 4.963652986
MESH:D005756 Gastritis Acetaminophen 3.1216983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.3916973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.7416417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 10.9916452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 10.9916452187
MESH:D005909 Glioblastoma monodansylcadaverine 5.0016170020
MESH:D006042 Goiter perchlorate 4.8018801409
MESH:D006330 Heart Defects, Congenital nitrofen 3.9116080930
MESH:D006333 Heart Failure Isoproterenol 9.8618097624
MESH:D006333 Heart Failure pirinixic acid 9.8620558911
MESH:D006333 Heart Failure Selenium 9.8617162251
MESH:D006345 Heart Septal Defects, Ventricular methyl cellosolve 5.236499821
MESH:D006394 Hemangiosarcoma Pentachlorophenol 4.5715200160
MESH:D006461 Hemolysis methyl cellosolve 4.9017874071
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.9116366002
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.0818665440 17276928 15929193
MESH:D006505 Hepatitis Carbon Tetrachloride 18.2619110552 19900420
MESH:D006505 Hepatitis Dichlorodiphenyl Dichloroethylene 18.2616487989
MESH:D006505 Hepatitis Thioacetamide 18.2616456712
MESH:D006505 Hepatitis Zymosan 18.2619110552
MESH:D006529 Hepatomegaly Amiodarone 11.6915265979
MESH:D006529 Hepatomegaly Dicofol 11.692387028
MESH:D006529 Hepatomegaly pirinixic acid 11.6919772884 18467677 19176532 16221962
MESH:D006548 Hernia, Diaphragmatic marker/mechanism 11685700
MESH:D006548 Hernia, Diaphragmatic nitrofen 3.727760232 16292651 12194112 10898222 15756563 10359170 16080930 10646786 12746050 9698600 15088113 11409163 16720372 15185205 16473863 11057544 15136996 9473106 11588001 12407540 15793718 12904592 12505043 10693666 9476886 7576705 16490937 15578192 17245593 12759764 11584395 17270546 12547725 11685700 18280291 15707848 11076806 10370017 8863223 9859898 18280292 11329586 16863852 7520565 10541330 12021965 9575882 18958481 15764645 17618886 11051153 10370016 10898224
MESH:D006689 Hodgkin Disease sodium arsenite 2.7112676792
MESH:D006930 Hyperalgesia Acetaminophen 2.2716870215
MESH:D017588 Hyperandrogenism Flutamide 4.9015356085
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.9816899240
MESH:D006937 Hypercholesterolemia Amiodarone 3.398137927 9751232
MESH:D006943 Hyperglycemia pirinixic acid 2.7120558911
MESH:D006948 Hyperkinesis Clozapine 4.3616046005
MESH:D006965 Hyperplasia Diethylstilbestrol 3.9012960047 14722030
MESH:D006973 Hypertension Phenylephrine 2.858949925 12717712
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.5515338365
MESH:D006980 Hyperthyroidism Methimazole 5.0914678291
MESH:D006984 Hypertrophy Isoproterenol 9.3712791704
MESH:D006984 Hypertrophy Phenylephrine 9.3718502941 12791704
MESH:D007021 Hypospadias Diethylstilbestrol 9.4716002989
MESH:D007021 Hypospadias Ethinyl Estradiol 9.4716945680 16569931
MESH:D007022 Hypotension Isoproterenol 4.296740701
MESH:D007037 Hypothyroidism Amiodarone 10.0417991464 18020914
MESH:D007037 Hypothyroidism Methimazole 10.0418031379
MESH:D007246 Infertility Diethylstilbestrol 3.8415036965
MESH:D007247 Infertility, Female Dicofol 8.9711762692 10631594
MESH:D007247 Infertility, Female Ethinyl Estradiol 8.9712013081
MESH:D007248 Infertility, Male Dichlorodiphenyl Dichloroethylene 17.1312948891 17192596
MESH:D007248 Infertility, Male Ethinyl Estradiol 17.1317937319
MESH:D007248 Infertility, Male methyl cellosolve 17.133987992
MESH:D007248 Infertility, Male sodium arsenite 17.1312646999 15346721
MESH:D007248 Infertility, Male vinclozolin 17.1316467254
MESH:D007249 Inflammation Flavonoids 12.6317296493
MESH:D007249 Inflammation Iodine 12.6316001271
MESH:D007249 Inflammation Lipopolysaccharides 12.6317963957 12878042 9205823 17237260 17255318
MESH:D007249 Inflammation Tamoxifen 12.6319457130
MESH:D007249 Inflammation Zymosan 12.6311289658 8014878
MESH:D007251 Influenza, Human Selenium 3.6416624496
MESH:D007333 Insulin Resistance bisphenol A 6.0716393666
MESH:D007333 Insulin Resistance pirinixic acid 6.0716306350
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.1217255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.2917553498
MESH:D007674 Kidney Diseases Acetaminophen 4.8512587719 15629191
MESH:D007674 Kidney Diseases sodium arsenite 4.8520008137
MESH:D007676 Kidney Failure, Chronic Selenium 3.4016518626
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 6.0914681315 15003126 16762066
MESH:D007680 Kidney Neoplasms Tamoxifen 6.0918625569
MESH:D007859 Learning Disorders Diethylstilbestrol 3.5317184923
MESH:D004915 Leukemia, Erythroblastic, Acute troglitazone 5.5816085563
MESH:D007970 Leukopenia Lipopolysaccharides 4.1515821434
MESH:D007984 Leydig Cell Tumor vinclozolin 4.1816417039
MESH:D017880 Limb Deformities, Congenital Dichlorodiphenyl Dichloroethylene 7.7412745335
MESH:D017880 Limb Deformities, Congenital methyl cellosolve 7.746499821
MESH:D008064 Lipidoses Amiodarone 10.9015342952 17567588
MESH:D008064 Lipidoses Clozapine 10.9017567588
MESH:D008064 Lipidoses Tamoxifen 10.9015342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.4921278145 16943688 17157831 11903743 17174718 11408273 17334410 16239168 16221502
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 7.5616136751 15673190 18339082 15996030 18187930 17708605 15057751 18376398 15362042 16027843 15959796 12898905 13678700 18412020 17900296 17805973 17640975 12546737 15123356 18210741 15931870 12741479 12445421 16248980 15052691 15730626 18166357 18279442 17976157 12586293 18481824 15818738 12666154 15338365 17766677 10355542 18263696 18395914 18472094 17557913 16015684 18054572 15370692 18429990 16097048 17761835 15925388 18205269 17944888 17721639 14748882 18251166 14716833 12632514 17869086 17714472 18418968 17823541 12649538 12389079 16192424 18472332 12632512 17631135 12958196 17698563 16638106 14724832 12445418 14716496 16033810 18395095 17922224 16011737 18006644 12667390 15876570 17481882 16116963 18420326 15893842 17565644 15650968 12609069 11481614 18156304 18317297 20821823 17525996 18705752 18277467 14512876 14620537
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 7.5615081153 17534399 16169303 15086199 16009107 15842777 15763062 16570917 15577212 18237412 17465448 15366600 15067225 14659978 17724770 14726149 15479170 17640959 16042886 15161499 17198567 15339415 18095165 17196135 15492853 17203207 15571005 15298665 18239293 15138612 17432682 15591649 17666798 18637143 18364076 12925901 15942678 15733078 18672772 16627068 17036385 16270385 17719030 15723089 15099470 18210741 14709902 15744066 17348192 15793283 15864749 15798949 12918455 18567088 14643895 14568256 15504291 18629640 17881167 16544323 15369754 18371158 15383259 17201889 16603200
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 7.5612878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 7.5615474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 7.5618564211
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 7.5615158331 16098781 16126171 12891558 18031379 18416461 17292413 16097051 18458672 18295389 15288472 12679928 16489207 12085344 18615449 15362042 16511523 14739098 16343077 11172339 12557150 15474484 15465738 17127702 15716488 15078482 15316131 12175628 16248980 15075984 17355460 15095483 18380797 15288473 18606216 12531686 17629604 18395095 18032466 10677585 18263696 11682029 17050028 15334695 11481614
MESH:D008107 Liver Diseases Acetaminophen 5.5316610002 12969438 19784758 19460945 11587558 16611625 12587719 19014921
MESH:D008107 Liver Diseases Carbon Tetrachloride 5.5316246199 16964402 15720792 17285989 15830285
MESH:D008107 Liver Diseases Thioacetamide 5.5315158337 16337175 18374380
MESH:D017093 Liver Failure Carbon Tetrachloride 3.6315123358
MESH:D017114 Liver Failure, Acute Acetaminophen 19.3517185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 19.3516899240 14706259
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 19.3517457977
MESH:D017114 Liver Failure, Acute Thioacetamide 19.3515313186 17276928 15633222 12479984
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 18.2019294768
MESH:D008113 Liver Neoplasms Diethylstilbestrol 18.2016712894 15890375
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 18.203113478 15890375
MESH:D008113 Liver Neoplasms Pentachlorophenol 18.2010696769
MESH:D008113 Liver Neoplasms pirinixic acid 18.2016377806 20007298 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 18.2016712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 18.2016684651
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 8.0115583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 8.016150874 15603536 1848544
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 8.011423854
MESH:D008133 Long QT Syndrome Amiodarone 3.1611989578 17391786 15350150
MESH:D008171 Lung Diseases Amiodarone 10.3212587719
MESH:D008171 Lung Diseases nitrofen 10.3217245593 16863852 9859898 9614859
MESH:D008171 Lung Diseases sodium arsenite 10.3219095001
MESH:D017563 Lung Diseases, Interstitial Amiodarone 3.9218516814
MESH:D055370 Lung Injury Lipopolysaccharides 3.4821114838
MESH:D008175 Lung Neoplasms ciglitazone 4.3015899809
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 4.3019555203 16061637 11884234
MESH:D008175 Lung Neoplasms sodium arsenite 4.3016712894 17077188 19931552 15276417 17306315
MESH:D008175 Lung Neoplasms Tamoxifen 4.3018625569
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.6015166399
MESH:D008223 Lymphoma Diethylstilbestrol 6.8415700306
MESH:D008223 Lymphoma Pentachlorophenol 6.8412669308
MESH:D008231 Lymphopenia methyl cellosolve 5.233699323
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.9616002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.2219428831
MESH:D008325 Mammary Neoplasms, Experimental Iodine 8.1215922087
MESH:D008325 Mammary Neoplasms, Experimental Selenium 8.1215318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 8.1219196722 11731420 16827153 19196723 14580682
MESH:D020149 Manganese Poisoning Tamoxifen 3.9919453300
MESH:D008545 Melanoma sodium arsenite 2.9419082730 16487513
MESH:D008545 Melanoma Tamoxifen 2.9419393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.6415990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.0319513568
MESH:D001523 Mental Disorders Clozapine 6.5816856516
MESH:D001523 Mental Disorders Haloperidol 6.5816856516
MESH:D008654 Mesothelioma Selenium 2.5515107826
MESH:D024821 Metabolic Syndrome X Clozapine 3.9619142101
MESH:D009102 Multiple Organ Failure Zymosan 4.7115241586 10479408 10890648 17724436 15834315 15213630 18160304 12130978 12879239 15259001
MESH:D009135 Muscular Diseases pirinixic acid 2.9716239165
MESH:D009181 Mycoses Amiodarone 4.3417974566 12754197
MESH:D009203 Myocardial Infarction Isoproterenol 5.1817052832 16538859 19595682 16584858 15740881 16697266 19172585
MESH:D009203 Myocardial Infarction pirinixic acid 5.1819151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.5216411023
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.3119393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3119410462
MESH:D009369 Neoplasms Diethylstilbestrol 6.5615313581
MESH:D009369 Neoplasms pirinixic acid 6.5617405874
MESH:D009369 Neoplasms sodium arsenite 6.5611559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.1420056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.4419200415 19189210 19196722
MESH:D018301 Neoplasms, Mesothelial Pentachlorophenol 6.1010696769
MESH:D009422 Nervous System Diseases Dicofol 5.221856875
MESH:D009421 Nervous System Malformations bisphenol A 8.2011399458 16427766
MESH:D009421 Nervous System Malformations Diethylstilbestrol 8.2011399458
MESH:D009436 Neural Tube Defects sodium arsenite 2.7812854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.4318514411
MESH:D009765 Obesity Clozapine 4.1418515891 19142110
MESH:D009765 Obesity pirinixic acid 4.1420558911
MESH:D009845 Oligospermia methyl cellosolve 4.633987992
MESH:D010049 Ovarian Diseases bisphenol A 4.4411985600
MESH:D010051 Ovarian Neoplasms Mifepristone 4.5016525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 4.5015276417 17306315
MESH:D010146 Pain Acetaminophen 1.9616870215
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.1811578682
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 3.1716702228
MESH:D010538 Peritonitis Zymosan 4.3518557954 15979727 19088179 17371808 19641140 14761945 15259001 18760300 17826846 11985352 18977430
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.6114722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.1415687265 16977796
MESH:D010954 Plasmacytoma Selenium 4.3315087411
MESH:D011014 Pneumonia Lipopolysaccharides 4.0112224865 11605937
MESH:D011085 Polycystic Ovary Syndrome Flutamide 4.5215356085
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 18.8610548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 18.8617184923
MESH:D011297 Prenatal Exposure Delayed Effects methyl cellosolve 18.866499817 7974496 12530607
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 18.8618042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.3918220299
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 3.7120887781
MESH:D011471 Prostatic Neoplasms bisphenol A 2.0116740699
MESH:D011471 Prostatic Neoplasms Dicofol 2.0112584743
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.0115846301 17136230 15046698
MESH:D011471 Prostatic Neoplasms Flutamide 2.013169114
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 2.0115721890
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.0116039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0115067354
MESH:D011472 Prostatitis vinclozolin 4.3918629315
MESH:D011537 Pruritus Ethinyl Estradiol 2.7716919318 15861022
MESH:D011595 Psychomotor Agitation Haloperidol 4.4211575062
MESH:D011618 Psychotic Disorders Clozapine 7.8115331141
MESH:D011618 Psychotic Disorders Haloperidol 7.8111575062
MESH:D011629 Puberty, Precocious bisphenol A 4.2410548101
MESH:D011654 Pulmonary Edema Isoproterenol 4.6910903255
MESH:D011658 Pulmonary Fibrosis Amiodarone 5.4011597910 12832656 12490602
MESH:D011658 Pulmonary Fibrosis troglitazone 5.4018162602
MESH:D015427 Reperfusion Injury pirinixic acid 2.1019058328
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.3610835634
MESH:D012559 Schizophrenia Clozapine 3.7517667964 17726453 20168265 19369910 16141801 18806925 18855531 20107430 11151749 20521326 20580759 20452607 20521320 11763009 17123785
MESH:D012559 Schizophrenia Haloperidol 3.7518513383 20107430 19369910 1830565
MESH:D018805 Sepsis Zymosan 4.2011441115
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.5418724381
MESH:D012852 Sinusitis Phenylephrine 4.167327846
MESH:D012878 Skin Neoplasms sodium arsenite 2.4319524636 18572023
MESH:D013088 Spermatocele Diethylstilbestrol 16.9116002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 16.9116709447
MESH:D013088 Spermatocele Tamoxifen 16.9116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.4919457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.3712854658
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.7112587719
MESH:D013160 Splenic Neoplasms Pentachlorophenol 5.7510696769
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 3.0016033868
MESH:D013274 Stomach Neoplasms troglitazone 3.0015930296
MESH:D013276 Stomach Ulcer Amiodarone 2.8518087811
MESH:D019966 Substance-Related Disorders bisphenol A 3.4416684133 16045194
MESH:D013610 Tachycardia Amiodarone 3.7711238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 8.8119225199
MESH:D017180 Tachycardia, Ventricular Haloperidol 8.8120210726
MESH:D013733 Testicular Diseases methyl cellosolve 4.546499806
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.6915821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.1111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.6915669648
MESH:D013959 Thyroid Diseases Amiodarone 10.8319731979
MESH:D013959 Thyroid Diseases Thyroxine 10.8319910387
MESH:D013971 Thyrotoxicosis Amiodarone 4.3219584973 18020914
MESH:D016171 Torsades de Pointes Amiodarone 3.6511989578 17467628
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 6.9516712894 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 6.9516712894 16452187 11723127 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 6.9517572228 16712894 8653321
MESH:D014570 Urologic Diseases Dichlorodiphenyl Dichloroethylene 5.1816487989
MESH:D014581 Urticaria Acetaminophen 2.4810982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 7.9616175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 7.9611813266
MESH:D014591 Uterine Diseases bisphenol A 11.9614652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 11.9614652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 7.7515809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 7.7514692618
MESH:D014605 Uveitis Zymosan 4.8411006244
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 3.9016513791 16002989
MESH:D014652 Vascular Diseases sodium arsenite 3.8817056641
MESH:D014689 Venous Insufficiency coumarin 5.2212708602
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.0515869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Isoproterenol 4.5918097624
MESH:D020257 Ventricular Remodeling Isoproterenol 5.1418097624
MESH:D015430 Weight Gain Clozapine 4.0016141801 20107430 16402076 20564506 17502770 20521320
MESH:D015431 Weight Loss Clozapine 4.5317933447
Pathway ID Pathway Name
REACT:71 Gene Expression
KEGG:04080 Neuroactive ligand-receptor interaction
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36507
    • No data
    No data
    Releated drug ID Related drug Name
    PA451746tretinoin
    PA450221levothyroxine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00279 agonist Thyrolar Hormone Replacement Agents
    DB00451 agonist Thyrolar Antithyroid Agents
    DB00509 agonist Dextrothyroxine Antihyperlipidemics
    DB01583 agonist Liotrix Hormone Replacement Agents
    DB03176 - 3,5-Dichloro-4-[(4-Hydroxy-3-Isopropylphenoxy)Phenylacetic Acid
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved