AutismKB 2.0

Annotation Detail for TIAL1


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Basic Information Top
Gene Symbol:TIAL1 ( MGC33401,TCBP,TIAR )
Gene Full Name: TIA1 cytotoxic granule-associated RNA binding protein-like 1
Band: 10q26.11
Quick LinksEntrez ID:7073; OMIM: 603413; Uniprot ID:TIAR_HUMAN; ENSEMBL ID: ENSG00000151923; HGNC ID: 11804
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1944Breast cancer
2120Rabies
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of TIAL1 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of TIAL1 mRNAaffects expression 21346803
C507359 2-aziridin-1-yl-3-((2-((2-(3-aziridin-1-yl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)thio)ethoxy)ethyl)thio)naphthoquinone 2-aziridin-1-yl-3-((2-((2-(3-aziridin-1-yl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)thio)ethoxy)ethyl)thio)naphthoquinone results in decreased expression of TIAL1 proteindecreases expression 15642166
D000082 Acetaminophen Acetaminophen affects the expression of TIAL1 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of TIAL1 mRNAaffects expression 16483693
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TIAL1 mRNAdecreases expression 19150397
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of TIAL1 mRNAincreases expression 15336504
C014347 decitabine [decitabine co-treated with Depsipeptides] results in decreased expression of TIAL1 mRNAaffects cotreatment|decreases expression 17064661
D047630 Depsipeptides [decitabine co-treated with Depsipeptides] results in decreased expression of TIAL1 mRNAaffects cotreatment|decreases expression 17064661
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of TIAL1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of TIAL1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TIAL1 mRNAaffects cotreatment|increases expression 17942748
D005472 Fluorouracil TIAL1 protein affects the susceptibility to Fluorouracilaffects response to substance 15548681
C006253 pirinixic acid pirinixic acid results in decreased expression of TIAL1 mRNAdecreases expression 17426115
C030984 pyrene pyrene results in increased expression of TIAL1 mRNAincreases expression 15963578
D013629 Tamoxifen Tamoxifen affects the expression of TIAL1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TIAL1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of TIAL1 mRNAincreases expression 17942748
D014212 Tretinoin Tretinoin results in decreased expression of TIAL1 mRNAdecreases expression 16012519
D014415 Tunicamycin Tunicamycin results in decreased expression of TIAL1 mRNAdecreases expression 17127020
D014810 Vitamin E Vitamin E results in decreased expression of TIAL1 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.5214745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8114514962 11752688 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.5218287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9117505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.0818653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.3014692618
MESH:D000230 Adenocarcinoma Fluorouracil 4.3017638652
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.7816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.7816835633
MESH:D000505 Alopecia Tretinoin 3.5815955085
MESH:D000740 Anemia Fluorouracil 8.5516511603 15504547 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.5511748828
MESH:D000799 Angioedema Acetaminophen 3.8110982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.1115885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.1116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2516292516
MESH:D001249 Asthma Tretinoin 2.3316456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001471 Barrett Esophagus Tretinoin 4.3616935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.0419483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.0412125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 15.0416206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7315746008
MESH:D001943 Breast Neoplasms decitabine 2.3218320071 19208741
MESH:D001943 Breast Neoplasms Fluorouracil 2.3218357371 19217205 16110121 15136595 16557594 16595493 18608205
MESH:D001943 Breast Neoplasms Tamoxifen 2.3219011961 19289846 17049068 19244106 20390343 17242785 20544844 18351453 19221464 19059307 19487384 11161223 19142967 18855134 17261762 18997820 19115204 18629630 15668708 16873071 17893378 20065188 18815881 18821012 19410462 16273361 19189212 20135344 19189210 20859285 21138602 19155303 19084267 16202921 15565566 18984771 18425577 20005174 19200415 19066611 16818667 17440819 21152245 19103187 19288272
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3220435547
MESH:D001943 Breast Neoplasms Tretinoin 2.3216166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.5516813970
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8916050911
MESH:D002276 Carcinoid Tumor Fluorouracil 4.6416051944
MESH:D002277 Carcinoma Fluorouracil 8.0617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.0616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4719066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.1316168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.3116705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.3116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.313084413
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 11.3118930000 16332177 17088986 17045692 17971768 16799960
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.3116924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.311917145
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.0018695887
MESH:D002294 Carcinoma, Squamous Cell decitabine 7.5319215824
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 7.5316757204 17066447 18986760 16280240
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.5316096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5717572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3418850075 18670907 16120746
MESH:D002386 Cataract Acetaminophen 7.1410977129
MESH:D002386 Cataract Tretinoin 7.1417460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 6.546135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.5420889678
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.5516129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1216835633
MESH:D002779 Cholestasis Ethinyl Estradiol 7.6316105132 15861022 11677210 17110522 16919318 17333356 17681005
MESH:D002779 Cholestasis pirinixic acid 7.6319176532
MESH:D002822 Choriocarcinoma Tretinoin 5.1316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.7016354765 8697196 15340226 12621046 15668235
MESH:D002972 Cleft Palate Tretinoin 5.709407595
MESH:D003092 Colitis Tretinoin 3.6617035595
MESH:D003110 Colonic Neoplasms decitabine 3.8417616700
MESH:D003110 Colonic Neoplasms Fluorouracil 3.8416510598 15001691 17287894 17018589 17172411 17016597 16340194 17725105 17169374 18772588
MESH:D015179 Colorectal Neoplasms decitabine 2.6218981723
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.6217454858 16391804 18802399 20501625 18383874 18448328 17695437 15148649 17594712 17401013 17094418 14970324 16282729 18288408 17016601 18949393 16524972 15289873 16303861 18509181 16331619 17255274
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0214669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7410048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.748800419 9224671 14991402 16925845 9664655 9142499 9125849 10589399 17551590 9211117
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.7419769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.7618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.7618551238
MESH:D007644 Darier Disease Fluorouracil 4.7616733453
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3219031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4018249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6617107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.4419279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 8.8321346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 8.8321346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 8.8319370779 11529661 16227642 14725611 18713872 10915739 12540782 11461765 12958197 19739265 10774834 17906064 16109766 11739529 16081117 19416960 16177239 12705907 17522070 18071297 12594235 11287661 15968718 16781746 14550746 11743745 2444490 19164858 19923254 11421492 14986274 12153990 19420014 16393943 12392966 15619225 10663392 11834606 16485898 17562736 19085960
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.8320420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7311462148
MESH:C538011 Eales disease Vitamin E 4.689068938
MESH:D004487 Edema pirinixic acid 6.4012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.4011000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.8518230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.8518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.8112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.8119031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.0919294695
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.3419155303 16202921 20544844 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 7.3416569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9810568697 9294722
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.4720426865
MESH:D004938 Esophageal Neoplasms Fluorouracil 4.4717638652 16337965 16481741 16785472 15173087
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.7211564622
MESH:D005124 Eye Abnormalities Tretinoin 8.729664655 16938888
MESH:D005234 Fatty Liver Ethinyl Estradiol 12.8115345470
MESH:D005234 Fatty Liver pirinixic acid 12.8120131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 12.8114986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4211858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4914745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.1519069698
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.4920067830
MESH:D005355 Fibrosis Tretinoin 8.4917994277
MESH:D005756 Gastritis Acetaminophen 3.6516983495
MESH:D005909 Glioblastoma Tretinoin 2.9817312396
MESH:D005910 Glioma Fluorouracil 2.8516145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5710696789
MESH:D006258 Head and Neck Neoplasms decitabine 12.8019215824
MESH:D006258 Head and Neck Neoplasms Fluorouracil 12.8018337622 15102660 15162350
MESH:D006258 Head and Neck Neoplasms Tretinoin 12.8016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.1316084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.0010048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 11.0014991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 11.0016080930
MESH:D006333 Heart Failure pirinixic acid 2.5120558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2911000095
MESH:D006529 Hepatomegaly pirinixic acid 8.1319772884 19176532 16221962 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.1315340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6916490937 16863852
MESH:D019584 Hot Flashes Vitamin E 3.9414716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0216959395 18606429 8697196 15340226 16354765
MESH:D006930 Hyperalgesia Acetaminophen 7.5016870215
MESH:D006930 Hyperalgesia Tretinoin 7.5016870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.5316778211
MESH:D006943 Hyperglycemia pirinixic acid 3.1420558911
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8918850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4212013081
MESH:D007248 Infertility, Male decitabine 6.6217581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.6217937319
MESH:D007249 Inflammation Tamoxifen 4.8119457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.8112200463 12878042
MESH:D007251 Influenza, Human Vitamin E 4.1916624496
MESH:D007333 Insulin Resistance pirinixic acid 2.6016306350
MESH:D007410 Intestinal Diseases Tretinoin 3.7317994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.8016580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.8017551590 15992940
MESH:D007674 Kidney Diseases Acetaminophen 5.8815629191 12587719
MESH:D007674 Kidney Diseases Vitamin E 5.8812488133
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.4716705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 17.4716705839
MESH:D007680 Kidney Neoplasms Fluorouracil 17.4716985049
MESH:D007680 Kidney Neoplasms Tamoxifen 17.4718625569
MESH:D007938 Leukemia decitabine 6.3618980019 19235587
MESH:D007938 Leukemia Tretinoin 6.3617143497
MESH:D007951 Leukemia, Myeloid decitabine 9.4319117987 17236224 18454857
MESH:D007951 Leukemia, Myeloid Tretinoin 9.4316932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute decitabine 3.9419010910 18206229 18704418 19387464 17679729 18460780
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.9417596541 19850784 16294345
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.4318055864
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1216766008 19029980 15748426 19075265 17712046 16891316 17217047 17294898 17506722 17649720 16331271 16788101 17368321 19225113 9834237 17107899 17339181 16823087 16935935 17361223 19035177 16140955 12679006 17301526 19642359
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.279224671
MESH:D008064 Lipidoses Tamoxifen 3.1215342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.6715474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.6718564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.6712878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.6716248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 6.6716169303
MESH:D008107 Liver Diseases Acetaminophen 1.6219014921 11587558 19460945 16610002 19784758 16611625 12969438 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2017185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 14.067678174
MESH:D008113 Liver Neoplasms Fluorouracil 14.0618383874 15113037 16603448 17045692
MESH:D008113 Liver Neoplasms pirinixic acid 14.0620007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tamoxifen 14.0616684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.0616984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 5.646135515 2876784 2876786
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.6412151625
MESH:D008171 Lung Diseases Vitamin E 3.1516863852
MESH:D008175 Lung Neoplasms Fluorouracil 4.8015246190
MESH:D008175 Lung Neoplasms Tamoxifen 4.8018625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8011884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 4.8011062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.7615086387
MESH:D008223 Lymphoma decitabine 3.3919470736
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7219428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.5914580682 19196722 11731420 16827153 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.5219453300
MESH:D008527 Medulloblastoma Tretinoin 2.7717453147
MESH:D008545 Melanoma decitabine 5.0816505122 17785578
MESH:D008545 Melanoma Tamoxifen 5.0812393984 19393235
MESH:D008545 Melanoma Tretinoin 5.0816752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1515990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5319513568
MESH:D008591 Meningomyelocele Tretinoin 4.3916940565
MESH:D009062 Mouth Neoplasms Fluorouracil 3.6016757204 18986760
MESH:D009101 Multiple Myeloma decitabine 3.3118172295
MESH:D009135 Muscular Diseases pirinixic acid 3.4716239165
MESH:D009190 Myelodysplastic Syndromes decitabine 7.4018608210 16882708 19010910 19157545
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.4017596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1219151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9812213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9116411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.2318551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.2318551238 7678174
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5019410462
MESH:D009369 Neoplasms decitabine 11.7017925555 19116145 19470736
MESH:D009369 Neoplasms Fluorouracil 11.7018600527 18239605 16928823
MESH:D009369 Neoplasms pirinixic acid 11.7017405874
MESH:D009369 Neoplasms Tretinoin 11.7016946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.9719196722 19189210 19200415
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.3814600291
MESH:D009421 Nervous System Malformations Tretinoin 9.389125849
MESH:D009436 Neural Tube Defects Tretinoin 3.029142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8318514411
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.4116436463
MESH:D009765 Obesity pirinixic acid 1.8020558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.7512819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.7516049721
MESH:D010051 Ovarian Neoplasms decitabine 4.9219331143 19259094
MESH:D010051 Ovarian Neoplasms Tretinoin 4.9216936753
MESH:D010146 Pain Acetaminophen 6.4616870215
MESH:D010146 Pain Tretinoin 6.4616870215
MESH:D010190 Pancreatic Neoplasms decitabine 8.5919294695
MESH:D010190 Pancreatic Neoplasms Fluorouracil 8.5916500647 19003803 15113037 16929163
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.5915976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6511578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5218163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.1611222880 11118676 11399792 11896295
MESH:D055728 Primary Myelofibrosis decitabine 4.6917616702
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.6118626508 19082440
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.6115067354
MESH:D011471 Prostatic Neoplasms Vitamin E 2.6115084515
MESH:D011507 Proteinuria Tretinoin 3.5616636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.2815861022 16919318
MESH:D011625 Pterygium Tretinoin 4.7616723453
MESH:D012004 Rectal Neoplasms Fluorouracil 3.9718722050 18286688 16160472 15538739
MESH:D015427 Reperfusion Injury pirinixic acid 2.3619058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8018990726
MESH:D012208 Rhabdomyosarcoma decitabine 10.8119155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 10.8116116481 16283617
MESH:D012640 Seizures 2,4-dinitrotoluene 5.7718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.7718551238
MESH:D012871 Skin Diseases Vitamin E 2.4318709164
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 9.318532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.3116192470
MESH:D012878 Skin Neoplasms Tretinoin 9.3116467112
MESH:D013088 Spermatocele Ethinyl Estradiol 11.4716709447
MESH:D013088 Spermatocele Tamoxifen 11.4716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0019457130
MESH:D013274 Stomach Neoplasms decitabine 3.4119037991
MESH:D013274 Stomach Neoplasms Fluorouracil 3.4118567086 17498489 16951190 18396642 19015929 19084572 17172411 17522103 16424979 15786421
MESH:D013274 Stomach Neoplasms Tretinoin 3.4117261132
MESH:D020521 Stroke Vitamin E 3.4816517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8712697716
MESH:D013964 Thyroid Neoplasms decitabine 7.1817967635
MESH:D013964 Thyroid Neoplasms Tretinoin 7.1817045167 16026305
MESH:D014062 Tongue Neoplasms Fluorouracil 9.7016280240
MESH:D014062 Tongue Neoplasms Tretinoin 9.7016051514
MESH:D014376 Tuberculosis Tretinoin 3.2016040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 11.8016049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.8016049721
MESH:D001749 Urinary Bladder Neoplasms decitabine 11.8019087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 11.8017572228 8653321 16712894
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.8710091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.8710091137
MESH:D014581 Urticaria Acetaminophen 2.9410982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 9.3216803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.3216129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2614692618
MESH:D014604 Uveal Neoplasms decitabine 12.7317785578
MESH:D014604 Uveal Neoplasms Tretinoin 12.7316752155
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5015869587 14671159
MESH:D014820 Vitiligo Tretinoin 4.0216761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2215886252
MESH:D009396 Wilms Tumor Tretinoin 3.9316287080
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36513
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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