AutismKB 2.0

Annotation Detail for TJP1


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Basic Information Top
Gene Symbol:TJP1 ( DKFZp686M05161,MGC133289,ZO-1 )
Gene Full Name: tight junction protein 1 (zona occludens 1)
Band: 15q13.1
Quick LinksEntrez ID:7082; OMIM: 601009; Uniprot ID:ZO1_HUMAN; ENSEMBL ID: ENSG00000104067; HGNC ID: 11827
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05120Epithelial cell signaling in Helicobacter pylori infection
hsa04540Gap junction
hsa04530Tight junction
hsa04520Adherens junction
hsa05110Vibrio cholerae infection
Pathway IDPathway Name
Membrane Trafficking
Apoptosis
Pathway IDPathway Name
200132Nephrin/Neph1 signaling in the kidney podocyte
200105E-cadherin signaling in the nascent adherens junction
No data
Pathway IDPathway Name
500272Apoptotic cleavage of cell adhesion proteins
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1770Melanoma
1896Adrenoleukodystrophy
1904Diabetes mellitus
1997Dental plaque
2053Colon cancer
2074Asthma
2075Heart failure
2129Thyroid cancer
2181Liver metastases
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C070379 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein]affects localization|decreases reaction 16716901
C457499 2-chloro-5-nitrobenzanilide 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan affects the localization of TJP1 protein]affects localization|decreases reaction 19252288
C457499 2-chloro-5-nitrobenzanilide 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan results in decreased expression of TJP1 mRNA]decreases expression|decreases reaction 19252288
C457499 2-chloro-5-nitrobenzanilide 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan results in decreased expression of TJP1 protein]decreases expression|decreases reaction 19252288
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal results in decreased expression of TJP1 mRNAdecreases expression 12419474
D000079 Acetaldehyde Acetaldehyde affects the localization of TJP1 proteinaffects localization 17991733
D000079 Acetaldehyde chelerythrine inhibits the reaction [EGF protein inhibits the reaction [Acetaldehyde affects the localization of TJP1 protein]]affects localization|decreases reaction 17991733
D000079 Acetaldehyde EGF protein inhibits the reaction [Acetaldehyde affects the localization of TJP1 protein]affects localization|decreases reaction 17991733
D000079 Acetaldehyde PLCG1 protein affects the reaction [EGF protein inhibits the reaction [Acetaldehyde affects the localization of TJP1 protein]]affects localization|affects reaction|decreases reaction 17991733
D000079 Acetaldehyde Ro 32-0432 inhibits the reaction [EGF protein inhibits the reaction [Acetaldehyde affects the localization of TJP1 protein]]affects localization|decreases reaction 17991733
D000082 Acetaminophen Acetaminophen affects the expression of TJP1 mRNAaffects expression 17562736
D001374 Azacitidine Azacitidine results in increased expression of TJP1 mRNAincreases expression 18661270
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TJP1 mRNAdecreases expression 19150397
C006780 bisphenol A bisphenol A results in decreased expression of TJP1 mRNAdecreases expression 12075121
D020122 tert-Butylhydroperoxide 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein]affects localization|decreases reaction 16716901
D020122 tert-Butylhydroperoxide 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein]affects localization|decreases reaction 16716901
D020122 tert-Butylhydroperoxide Bucladesine inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein]affects localization|decreases reaction 16716901
D020122 tert-Butylhydroperoxide Go 6976 inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein]affects localization|decreases reaction 16716901
D020122 tert-Butylhydroperoxide Staurosporine inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein]affects localization|decreases reaction 16716901
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide affects the localization of TJP1 proteinaffects localization 16716901
C016299 chelerythrine chelerythrine inhibits the reaction [EGF protein inhibits the reaction [Acetaldehyde affects the localization of TJP1 protein]]affects localization|decreases reaction 17991733
D003513 Cycloheximide Cycloheximide inhibits the reaction [IFNG protein results in increased expression of TJP1 protein]decreases reaction|increases expression 16087364
D003513 Cycloheximide Cycloheximide results in decreased expression of TJP1 proteindecreases expression 16087364
D016572 Cyclosporine Cyclosporine results in increased expression of TJP1 mRNAincreases expression 20106945
C014347 decitabine [decitabine co-treated with trichostatin A] results in increased expression of TJP1 mRNAaffects cotreatment|increases expression 17524140
C014347 decitabine decitabine results in increased expression of TJP1 mRNAincreases expression 17524140
D003994 Bucladesine Bucladesine inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein]affects localization|decreases reaction 16716901
D004026 Dieldrin Dieldrin results in decreased expression of TJP1 proteindecreases expression 15082077
D004041 Dietary Fats Dietary Fats results in increased expression of TJP1 mRNAincreases expression 18042831
D004121 Dimethyl Sulfoxide Dimethyl Sulfoxide results in increased expression of TJP1 mRNAincreases expression 18661270
C007488 dinitrobenzenesulfonic acid ALOX5 protein affects the reaction [dinitrobenzenesulfonic acid affects the localization of TJP1 protein]affects localization|affects reaction 16670640
C007488 dinitrobenzenesulfonic acid dinitrobenzenesulfonic acid affects the localization of TJP1 proteinaffects localization 16670640
C007488 dinitrobenzenesulfonic acid dinitrobenzenesulfonic acid results in decreased expression of TJP1 proteindecreases expression 16680017
C007488 dinitrobenzenesulfonic acid Thalidomide inhibits the reaction [dinitrobenzenesulfonic acid results in decreased expression of TJP1 protein]decreases expression|decreases reaction 16680017
C007488 dinitrobenzenesulfonic acid zileuton inhibits the reaction [dinitrobenzenesulfonic acid affects the localization of TJP1 protein]affects localization|decreases reaction 16670640
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of TJP1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of TJP1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of TJP1 mRNAaffects cotreatment|decreases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of TJP1 mRNAdecreases expression 12075121
15576828
D017965 gamma-Linolenic Acid [gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of TJP1 proteinaffects cotreatment|increases expression|increases localization 16514648
D019833 Genistein Genistein results in decreased expression of TJP1 mRNAdecreases expression 12075121
C081021 Go 6976 Go 6976 inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein]affects localization|decreases reaction 16716901
D019307 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein]affects localization|decreases reaction 16716901
D006861 Hydrogen Peroxide Hydrogen Peroxide affects the expression of TJP1 mRNAaffects expression 18661270
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of TJP1 mRNAdecreases expression 12419474
D007455 Iodine [gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of TJP1 proteinaffects cotreatment|increases expression|increases localization 16514648
D007455 Iodine Iodine results in increased expression of and results in increased localization of TJP1 proteinincreases expression|increases localization 16514648
D001556 Lindane Lindane affects the localization of TJP1 proteinaffects localization 11532877
D001556 Lindane Lindane results in decreased expression of TJP1 proteindecreases expression 11532877
D001556 Lindane Lindane affects the localization of TJP1 proteinaffects localization 15194225
D001556 Lindane Lindane promotes the reaction [GJA1 protein binds to TJP1 protein]affects binding|increases reaction 15194225
D015735 Mifepristone Mifepristone results in increased expression of TJP1 mRNAincreases expression 17584828
C041786 palm oil palm oil results in increased expression of TJP1 mRNAincreases expression 18042831
D019800 Phenol Phenol affects the localization of TJP1 proteinaffects localization 19679145
C006253 pirinixic acid pirinixic acid results in decreased expression of TJP1 mRNAdecreases expression 18445702
D011692 Puromycin Aminonucleoside Puromycin Aminonucleoside affects the localization of TJP1 proteinaffects localization 15798086
C085989 Ro 32-0432 Ro 32-0432 inhibits the reaction [EGF protein inhibits the reaction [Acetaldehyde affects the localization of TJP1 protein]]affects localization|decreases reaction 17991733
D012643 Selenium [gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of TJP1 proteinaffects cotreatment|increases expression|increases localization 16514648
D012643 Selenium Selenium results in increased expression of and results in increased localization of TJP1 proteinincreases expression|increases localization 16514648
D019311 Staurosporine Staurosporine inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein]affects localization|decreases reaction 16716901
D013629 Tamoxifen Tamoxifen affects the expression of TJP1 mRNAaffects expression 17555576
C084178 telmisartan 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan affects the localization of TJP1 protein]affects localization|decreases reaction 19252288
C084178 telmisartan 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan results in decreased expression of TJP1 mRNA]decreases expression|decreases reaction 19252288
C084178 telmisartan 2-chloro-5-nitrobenzanilide inhibits the reaction [telmisartan results in decreased expression of TJP1 protein]decreases expression|decreases reaction 19252288
C084178 telmisartan telmisartan affects the localization of TJP1 proteinaffects localization 19252288
C084178 telmisartan telmisartan results in decreased expression of TJP1 mRNAdecreases expression 19252288
C084178 telmisartan telmisartan results in decreased expression of TJP1 proteindecreases expression 19252288
C084178 telmisartan wortmannin inhibits the reaction [telmisartan affects the localization of TJP1 protein]affects localization|decreases reaction 19252288
C084178 telmisartan wortmannin inhibits the reaction [telmisartan results in decreased expression of TJP1 mRNA]decreases expression|decreases reaction 19252288
C084178 telmisartan wortmannin inhibits the reaction [telmisartan results in decreased expression of TJP1 protein]decreases expression|decreases reaction 19252288
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of TJP1 mRNAaffects cotreatment|decreases expression 17942748
D013792 Thalidomide Thalidomide inhibits the reaction [dinitrobenzenesulfonic acid results in decreased expression of TJP1 protein]decreases expression|decreases reaction 16680017
D013853 Thioacetamide Thioacetamide results in increased expression of TJP1 proteinincreases expression 15350541
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in increased expression of TJP1 mRNAincreases expression 16650747
D014212 Tretinoin CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of TJP1 mRNA]decreases reaction|increases expression 17035595
D014212 Tretinoin Tretinoin results in increased expression of TJP1 mRNAincreases expression 17035595
D014212 Tretinoin Tretinoin results in increased expression of TJP1 proteinincreases expression 17035595
D014212 Tretinoin Tretinoin results in increased expression of TJP1 mRNAincreases expression 16236135
C012589 trichostatin A trichostatin A results in increased expression of TJP1 mRNAincreases expression 18661270
C012589 trichostatin A [decitabine co-treated with trichostatin A] results in increased expression of TJP1 mRNAaffects cotreatment|increases expression 17524140
D002762 Cholecalciferol Cholecalciferol results in increased expression of TJP1 mRNAincreases expression 16508948
C009687 wortmannin wortmannin inhibits the reaction [telmisartan affects the localization of TJP1 protein]affects localization|decreases reaction 19252288
C009687 wortmannin wortmannin inhibits the reaction [telmisartan results in decreased expression of TJP1 mRNA]decreases expression|decreases reaction 19252288
C009687 wortmannin wortmannin inhibits the reaction [telmisartan results in decreased expression of TJP1 protein]decreases expression|decreases reaction 19252288
C066436 zardaverine zardaverine results in decreased localization of TJP1 proteindecreases localization 15082077
C063449 zileuton zileuton inhibits the reaction [dinitrobenzenesulfonic acid affects the localization of TJP1 protein]affects localization|decreases reaction 16670640
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.0514745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.1014514962 11752688 15322242
MESH:D000014 Abnormalities, Drug-Induced Thalidomide 7.108333272
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 10.4517505938
MESH:D000152 Acne Vulgaris zileuton 10.4520436887
MESH:D055371 Acute Lung Injury pirinixic acid 7.9118653653
MESH:D055371 Acute Lung Injury zileuton 7.9117118201
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 3.8714692618
MESH:D000230 Adenocarcinoma Genistein 3.8711473722
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.2816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.2816835633
MESH:D000382 Agricultural Workers' Diseases Lindane 3.8912661182
MESH:D000505 Alopecia Tretinoin 3.2315955085
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 7.5010965797
MESH:D000690 Amyotrophic Lateral Sclerosis Thalidomide 7.5016510725
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.5311748828
MESH:D000799 Angioedema Acetaminophen 3.3510982225
MESH:D001161 Arteriosclerosis Dietary Fats 8.3315238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.3311256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 10.5615885639
MESH:D001169 Arthritis, Experimental Thalidomide 10.569598899
MESH:D001169 Arthritis, Experimental Tretinoin 10.5616412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.1416292516
MESH:D001249 Asthma Acetaldehyde 7.219600491
MESH:D001249 Asthma Tretinoin 7.2116456186
MESH:D001249 Asthma zileuton 7.2119214143 10181070 17944539 8598621 9620945 20332717 10764316
MESH:D001250 Asthma, Exercise-Induced zileuton 5.1010984370
MESH:D001321 Autistic Disorder Acetaminophen 1.4818445737
MESH:D001327 Autoimmune Diseases Cholecalciferol 4.5616142846
MESH:D001471 Barrett Esophagus Tretinoin 3.9416935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 18.4019483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 18.4012125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 18.4019483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 18.4016206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4415746008
MESH:D001859 Bone Neoplasms Phenol 4.7610556009
MESH:D001862 Bone Resorption bisphenol A 3.4311985600
MESH:D001913 Bowen's Disease Phenol 5.2519293009
MESH:D001929 Brain Edema zileuton 5.3819309543
MESH:D001943 Breast Neoplasms bisphenol A 5.2217123778
MESH:D001943 Breast Neoplasms decitabine 5.2218320071 19208741
MESH:D001943 Breast Neoplasms Dieldrin 5.2211859874 15770527
MESH:D001943 Breast Neoplasms Dietary Fats 5.2220435547
MESH:D001943 Breast Neoplasms Genistein 5.2217200150 16873071 16541309
MESH:D001943 Breast Neoplasms Lindane 5.2214688026
MESH:D001943 Breast Neoplasms Tamoxifen 5.2219289846 11161223 18997820 19084267 19059307 19200415 20065188 20544844 19155303 19011961 16273361 18629630 19103187 16202921 16818667 21138602 17242785 17893378 18351453 19410462 20005174 18815881 19244106 20390343 18984771 19189212 19066611 19221464 17440819 19189210 18425577 21152245 18821012 20859285 17261762 19288272 15565566 16873071 15668708 18855134 19115204 19142967 17049068 20135344 19487384
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.2220435547
MESH:D001943 Breast Neoplasms Tretinoin 5.2216166294 16443354 16873071
MESH:D016535 Bronchial Hyperreactivity zileuton 4.4112794006 12388339 12654629
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.1016813970
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.4116835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.0319066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.6616168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 10.103084413
MESH:D006528 Carcinoma, Hepatocellular Genistein 10.1016924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 10.1016924424
MESH:D006528 Carcinoma, Hepatocellular Thalidomide 10.1016313753
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 10.1017997003
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 10.101917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.5017123778
MESH:D002294 Carcinoma, Squamous Cell decitabine 4.2219215824
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.2216051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.1917572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.0918850075 18670907 16120746
MESH:D002310 Cardiomyopathy, Alcoholic Acetaldehyde 5.9810525098
MESH:D002318 Cardiovascular Diseases Genistein 6.3816332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 6.3816936243
MESH:D002386 Cataract Acetaminophen 6.2310977129
MESH:D002386 Cataract Tretinoin 6.2317460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 5.4220889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 5.4212371664
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.1016129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 13.9116835633
MESH:D018281 Cholangiocarcinoma Thalidomide 13.9118291259
MESH:D018281 Cholangiocarcinoma Thioacetamide 13.9118291259
MESH:D002779 Cholestasis Cyclosporine 11.2319486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.2317110522 16105132 17333356 11677210 15861022 17681005 16919318
MESH:D002779 Cholestasis pirinixic acid 11.2319176532
MESH:D002822 Choriocarcinoma Tretinoin 4.6616461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.0215668235 15340226 12621046 16354765 8697196
MESH:D002972 Cleft Palate Tretinoin 5.029407595
MESH:D003092 Colitis dinitrobenzenesulfonic acid 19.0816670640 16680017 15821759
MESH:D003092 Colitis Selenium 19.0817936198
MESH:D003092 Colitis Thalidomide 19.0816680017
MESH:D003092 Colitis Tretinoin 19.0817035595
MESH:D003110 Colonic Neoplasms decitabine 5.3817616700
MESH:D003110 Colonic Neoplasms Genistein 5.3817182828
MESH:D003110 Colonic Neoplasms zileuton 5.3818927292
MESH:D015179 Colorectal Neoplasms Azacitidine 2.7619934284
MESH:D015179 Colorectal Neoplasms decitabine 2.7618981723
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6517141729 14669216
MESH:D016510 Corneal Neovascularization Thalidomide 5.109301478
MESH:D003389 Cranial Nerve Diseases Thalidomide 5.819200351
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.5320055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Thalidomide 3.539200351
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.5314991402 9142499 17551590 16925845 10589399 9224671 9211117 8800419 9125849 9664655
MESH:D003424 Crohn Disease Thalidomide 3.9116078585
MESH:D003665 Decompression Sickness zileuton 5.7318309904
MESH:D003711 Demyelinating Diseases Tamoxifen 3.8919031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1818249437
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 3.8516647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.8517107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.0719279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 10.2216227642 11287661 14986274 12705907 11739529 11529661 16109766 10663392 12392966 12958197 19923254 14725611 10774834 17906064 11834606 16781746 16393943 10915739 11743745 14550746 19420014 17522070 19085960 11421492 19164858 12153990 15619225 12540782 2444490 15968718 16177239 19416960 16485898 18071297 17562736 11461765 19370779 19739265 16081117 18713872 12594235
MESH:D056486 Drug-Induced Liver Injury Selenium 10.2215131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 10.2220420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 10.2212963478
MESH:D056486 Drug-Induced Liver Injury zileuton 10.2217944539
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6019426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4011462148
MESH:D050171 Dyslipidemias Dietary Fats 3.1018367378
MESH:D004487 Edema pirinixic acid 13.0112083418
MESH:D004487 Edema Staurosporine 13.018273558
MESH:D004487 Edema Tetrachlorodibenzodioxin 13.0112711302 11000095
MESH:D004487 Edema zileuton 13.017812673 17118201 19703484 8273558 11698051 7990266 9831321
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.2918230668 16714409 15322242
MESH:D004489 Edema, Cardiac Tretinoin 10.2918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 7.4112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 7.4119031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 12.3719294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 12.3719294695
MESH:D018159 Endolymphatic Hydrops Dimethyl Sulfoxide 6.0620641076
MESH:D004714 Endometrial Hyperplasia Genistein 4.1016402032
MESH:D016889 Endometrial Neoplasms Genistein 10.5711473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 10.5719155303 17893378 16202921 20544844
MESH:D016889 Endometrial Neoplasms Tretinoin 10.5716569247
MESH:D004715 Endometriosis Mifepristone 7.7516134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.759294722 10568697
MESH:D019446 Endotoxemia zileuton 4.8715328337
MESH:D004802 Eosinophilia zileuton 4.4410764316 8621850
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 1.9420426865
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.6111564622
MESH:D005124 Eye Abnormalities Tretinoin 7.619664655 16938888
MESH:D005218 Fat Necrosis Thioacetamide 5.2216456712
MESH:D005234 Fatty Liver Cyclosporine 20.0319224547
MESH:D005234 Fatty Liver Dietary Fats 20.0317967931 18296743 19551842 19004024
MESH:D005234 Fatty Liver Ethinyl Estradiol 20.0315345470
MESH:D005234 Fatty Liver pirinixic acid 20.0319236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 20.0314986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.9316709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9811858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.0414745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.6919069698
MESH:D005355 Fibrosis Cyclosporine 17.2412639820 12168785
MESH:D005355 Fibrosis Dietary Fats 17.2418296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 17.2420067830
MESH:D005355 Fibrosis Tretinoin 17.2417994277
MESH:D005596 Fractures, Closed zileuton 5.3619544365
MESH:D005756 Gastritis Acetaminophen 3.1816983495
MESH:D005871 Giant Lymph Node Hyperplasia Thalidomide 5.8112701121
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.738708960
MESH:D005909 Glioblastoma Genistein 10.1016598420
MESH:D005909 Glioblastoma Tretinoin 10.1017312396
MESH:D005909 Glioblastoma trichostatin A 10.1018801729
MESH:D005910 Glioma Thalidomide 3.6116327979
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1010696789
MESH:D006258 Head and Neck Neoplasms decitabine 6.7119215824
MESH:D006258 Head and Neck Neoplasms Tretinoin 6.7116096774
MESH:D034381 Hearing Loss Dimethyl Sulfoxide 4.7620641076
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.6616084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.6210048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 5.629664655 14991402
MESH:D006333 Heart Failure pirinixic acid 5.9120558911
MESH:D006333 Heart Failure Selenium 5.9117162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9315720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9011000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.1415929193 17276928 18665440
MESH:D006505 Hepatitis Thioacetamide 3.7616456712
MESH:D006529 Hepatomegaly pirinixic acid 11.8318467677 16221962 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 11.8316120746 15340226 12621046
MESH:D006529 Hepatomegaly zileuton 11.838661344
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.5518606429 16959395 15340226 16354765 8697196
MESH:D006930 Hyperalgesia Acetaminophen 6.3516870215
MESH:D006930 Hyperalgesia Tretinoin 6.3516870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.1621332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.0916778211
MESH:D006943 Hyperglycemia pirinixic acid 2.7620558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.1721332399
MESH:D006973 Hypertension Cyclosporine 7.5810903974
MESH:D006973 Hypertension telmisartan 7.5816077267
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.5818670907 18850075
MESH:D006976 Hypertension, Pulmonary zileuton 4.3114726295
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3316569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery zileuton 5.1619309543
MESH:D007247 Infertility, Female Dieldrin 8.8010630421
MESH:D007247 Infertility, Female Ethinyl Estradiol 8.8012013081
MESH:D007248 Infertility, Male decitabine 5.6117581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 5.6117937319
MESH:D007249 Inflammation Dietary Fats 16.4620412841
MESH:D007249 Inflammation Iodine 16.4616001271
MESH:D007249 Inflammation Tamoxifen 16.4619457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 16.4612878042 12200463
MESH:D007249 Inflammation Thalidomide 16.4616134734
MESH:D007249 Inflammation zileuton 16.468960868 18309904 7812673 8621850 18059327 17118201 18295198 9831321
MESH:D015212 Inflammatory Bowel Diseases zileuton 3.9415339030
MESH:D007251 Influenza, Human Selenium 3.7016624496
MESH:D007333 Insulin Resistance bisphenol A 10.4316393666
MESH:D007333 Insulin Resistance Dietary Fats 10.4318457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 10.4316306350
MESH:D007410 Intestinal Diseases Tretinoin 3.2917994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.4816580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.4815992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.9415604871
MESH:D055623 Keratosis, Actinic Phenol 5.9519293009
MESH:D007674 Kidney Diseases Acetaminophen 4.8212587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 4.8218776723 8314463 10903974
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 8.5816518626
MESH:D007676 Kidney Failure, Chronic Selenium 8.5816518626
MESH:D007680 Kidney Neoplasms Cyclosporine 5.9912371664
MESH:D007680 Kidney Neoplasms Tamoxifen 5.9918625569
MESH:D007898 Leishmaniasis, Visceral Thalidomide 3.9716514283
MESH:D007938 Leukemia Azacitidine 12.8619148494
MESH:D007938 Leukemia decitabine 12.8619235587 18980019
MESH:D007938 Leukemia Genistein 12.8617468513 18980019
MESH:D007938 Leukemia Tretinoin 12.8617143497
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive zileuton 4.4219503090 19823023
MESH:D007951 Leukemia, Myeloid Azacitidine 13.6019077051
MESH:D007951 Leukemia, Myeloid decitabine 13.6017236224 19117987 18454857
MESH:D007951 Leukemia, Myeloid Tretinoin 13.6019285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 10.5217596541 18720364
MESH:D015470 Leukemia, Myeloid, Acute decitabine 10.5219387464 18704418 18206229 17679729 19010910 18460780
MESH:D015470 Leukemia, Myeloid, Acute Thalidomide 10.5218720364
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 10.5219850784 16294345 17596541
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 10.5218206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.9618055864
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 4.7419299654
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.8317217047 9834237 19029980 17506722 17368321 17649720 16140955 17339181 19035177 16788101 16331271 19075265 17301526 19642359 16766008 16891316 15748426 17712046 12679006 17107899 19225113 17361223 16935935 17294898 16823087
MESH:D017880 Limb Deformities, Congenital Thalidomide 7.3710473037
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.379224671
MESH:D008064 Lipidoses Tamoxifen 2.8015342952 17567588
MESH:D008103 Liver Cirrhosis Dietary Fats 6.1318296743
MESH:D008103 Liver Cirrhosis Thalidomide 6.1317174718 16943688
MESH:D008106 Liver Cirrhosis, Experimental Dimethyl Sulfoxide 14.1311682029
MESH:D008106 Liver Cirrhosis, Experimental Genistein 14.1317823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 14.1315474484
MESH:D008106 Liver Cirrhosis, Experimental Puromycin Aminonucleoside 14.1316570917
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 14.1318564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 14.1312878042
MESH:D008106 Liver Cirrhosis, Experimental Thalidomide 14.1315465738
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 14.1312557150 15078482 16097051 15716488 18606216 18295389 16511523 18395095 16248980 15474484 15288472 16126171 15288473 15316131 15334695 15075984 10677585 15095483 17292413 12531686 15362042 17629604 15465738 18032466 16343077 11481614 12175628 11172339 17050028 11682029 14739098 18416461 16098781 18263696 12679928 15158331 12891558 17127702 18458672 17355460 16489207 18615449 12085344 18031379 18380797
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 14.1318397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 5.8119014921 12969438 16610002 16611625 19460945 11587558 12587719 19784758
MESH:D008107 Liver Diseases Lindane 5.811715830
MESH:D008107 Liver Diseases Thioacetamide 5.8115158337 18374380 16337175
MESH:D017114 Liver Failure, Acute Acetaminophen 8.2316871587 17185352
MESH:D017114 Liver Failure, Acute Thioacetamide 8.2315633222 15313186 12479984 17276928
MESH:D008113 Liver Neoplasms Dieldrin 9.009539021 8742319
MESH:D008113 Liver Neoplasms pirinixic acid 9.0015890375 16377806 20007298
MESH:D008113 Liver Neoplasms Tamoxifen 9.0016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 9.0016984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 1.8112151625
MESH:D008175 Lung Neoplasms Acetaldehyde 4.3517372256
MESH:D008175 Lung Neoplasms Azacitidine 4.3521224363
MESH:D008175 Lung Neoplasms Tamoxifen 4.3518625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.3511884234 19555203
MESH:D008223 Lymphoma decitabine 3.0719470736
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.2819428831
MESH:D008325 Mammary Neoplasms, Experimental Genistein 11.7212929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Iodine 11.7215922087
MESH:D008325 Mammary Neoplasms, Experimental Selenium 11.7215318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 11.7219196722 11731420 19196723 14580682 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.0519453300
MESH:D008527 Medulloblastoma Tretinoin 2.5717453147
MESH:D008545 Melanoma decitabine 8.6516505122 17785578
MESH:D008545 Melanoma Tamoxifen 8.6512393984 19393235
MESH:D008545 Melanoma Thalidomide 8.6517089043 12829675 16098027
MESH:D008545 Melanoma Tretinoin 8.6516752155
MESH:D008545 Melanoma trichostatin A 8.6516505122
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.6915990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.0919513568
MESH:D008591 Meningomyelocele Tretinoin 3.9516940565
MESH:D008654 Mesothelioma Selenium 2.5815107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.2916801185
MESH:D009006 Monosomy Azacitidine 5.5819299654
MESH:D009101 Multiple Myeloma Azacitidine 14.5019549372 18443271
MESH:D009101 Multiple Myeloma decitabine 14.5018172295
MESH:D009101 Multiple Myeloma Thalidomide 14.5015867202 15744524 19112817 19112201 19372569 15741222 15920492 17168659 15939924 16445831
MESH:D009101 Multiple Myeloma trichostatin A 14.5018172295
MESH:D009135 Muscular Diseases pirinixic acid 3.0316239165
MESH:D009190 Myelodysplastic Syndromes Azacitidine 15.2618720364 19805378 17611569 17596541
MESH:D009190 Myelodysplastic Syndromes decitabine 15.2619010910 19157545 18608210 16882708
MESH:D009190 Myelodysplastic Syndromes Thalidomide 15.2618720364
MESH:D009190 Myelodysplastic Syndromes Tretinoin 15.2617596541
MESH:D009203 Myocardial Infarction Genistein 4.9317141266
MESH:D009203 Myocardial Infarction pirinixic acid 4.9319151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6312213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 7.1417141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.1416411023
MESH:D009298 Nasal Polyps zileuton 5.7310665187
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.3419393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3419410462
MESH:D009369 Neoplasms decitabine 12.9919116145 17925555 19470736
MESH:D009369 Neoplasms Dieldrin 12.998820588
MESH:D009369 Neoplasms Lindane 12.9912807735 16818664
MESH:D009369 Neoplasms pirinixic acid 12.9917405874
MESH:D009369 Neoplasms Tretinoin 12.9916946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.5019196722 19200415 19189210
MESH:D009401 Nephrosis Puromycin Aminonucleoside 6.0215829708 11170791
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.9417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.5719348381 18481113
MESH:D009404 Nephrotic Syndrome Puromycin Aminonucleoside 8.5716020936
MESH:D009421 Nervous System Malformations bisphenol A 25.8616427766 11399458
MESH:D009421 Nervous System Malformations Genistein 25.8616427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 25.8614600291
MESH:D009421 Nervous System Malformations Thalidomide 25.8616859833
MESH:D009421 Nervous System Malformations Tretinoin 25.869125849
MESH:D009436 Neural Tube Defects Tretinoin 2.739142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.4818514411
MESH:D009765 Obesity Dietary Fats 3.9520518802 21332399 20132043 18674790 11836018 17217161 18457598 16723640 19632207
MESH:D009765 Obesity pirinixic acid 3.9520558911
MESH:D010024 Osteoporosis Genistein 2.9419401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.6416169203
MESH:D010049 Ovarian Diseases bisphenol A 4.5011985600
MESH:D010051 Ovarian Neoplasms decitabine 16.5619331143 19259094
MESH:D010051 Ovarian Neoplasms Genistein 16.5619005980
MESH:D010051 Ovarian Neoplasms Mifepristone 16.5616525653
MESH:D010051 Ovarian Neoplasms Thalidomide 16.5616288038
MESH:D010051 Ovarian Neoplasms Tretinoin 16.5616936753
MESH:D010051 Ovarian Neoplasms trichostatin A 16.5619331143
MESH:D010146 Pain Acetaminophen 12.9816870215
MESH:D010146 Pain Phenol 12.9817610455
MESH:D010146 Pain Tretinoin 12.9816870215
MESH:D010146 Pain zileuton 12.9815935457
MESH:D010190 Pancreatic Neoplasms decitabine 7.6019294695
MESH:D010190 Pancreatic Neoplasms Tretinoin 7.6015976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 7.6019294695
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2411578682
MESH:D010212 Papilloma Hydrogen Peroxide 3.6212065085
MESH:D010291 Paresis Thalidomide 5.819200351
MESH:D010300 Parkinson Disease Dieldrin 3.3311445065 11181820 16112328 17291500 16809432
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7512520081
MESH:D010392 Pemphigus Phenol 5.9516522979 17163923
MESH:D010538 Peritonitis zileuton 4.7817371808
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 5.0111550810
MESH:D010864 Pilonidal Sinus Phenol 5.9519655223 15622588
MESH:D010954 Plasmacytoma Selenium 4.3915087411
MESH:D011041 Poisoning Phenol 4.278825745
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1018163543
MESH:D011230 Precancerous Conditions Cyclosporine 2.8112371664
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Thalidomide 3.9417031469
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 7.8910548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 7.8911399792 11118676 11222880 11896295
MESH:D055728 Primary Myelofibrosis decitabine 10.8417616702
MESH:D055728 Primary Myelofibrosis trichostatin A 10.8417616702
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 3.7720887781
MESH:D011471 Prostatic Neoplasms Azacitidine 2.3118324645
MESH:D011471 Prostatic Neoplasms bisphenol A 2.3116740699
MESH:D011471 Prostatic Neoplasms Cholecalciferol 2.3117024972
MESH:D011471 Prostatic Neoplasms Genistein 2.3115256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms Lindane 2.3114688026 12661182
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.3115067354
MESH:D011471 Prostatic Neoplasms Thalidomide 2.3116729912
MESH:D011471 Prostatic Neoplasms trichostatin A 2.3119789329 18798265
MESH:D011507 Proteinuria telmisartan 8.3816077267
MESH:D011507 Proteinuria Tretinoin 8.3816636307
MESH:D011536 Prurigo Thalidomide 5.8112755975
MESH:D011537 Pruritus Ethinyl Estradiol 8.3016919318 15861022
MESH:D011537 Pruritus zileuton 8.3019657356 17827870
MESH:D011565 Psoriasis Cyclosporine 2.0416882103
MESH:D011625 Pterygium Tretinoin 4.3016723453
MESH:D011629 Puberty, Precocious bisphenol A 4.3010548101
MESH:D011654 Pulmonary Edema zileuton 4.9318309904
MESH:D015427 Reperfusion Injury pirinixic acid 6.0819058328
MESH:D015427 Reperfusion Injury zileuton 6.089865762 15266012
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3718990726
MESH:D012208 Rhabdomyosarcoma decitabine 9.4519155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 9.4516116481 16283617
MESH:D012220 Rhinitis Acetaldehyde 8.1317050345
MESH:D012220 Rhinitis zileuton 8.1320332717
MESH:D019873 Schnitzler Syndrome Thalidomide 5.4516096327
MESH:D012640 Seizures Lindane 3.307539098 12842176 15475178
MESH:D012852 Sinusitis zileuton 5.0310665187
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 11.5212065085
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 11.528532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 11.5216192470
MESH:D012878 Skin Neoplasms Tretinoin 11.5216467112
MESH:D020181 Sleep Apnea, Obstructive zileuton 5.3719118273
MESH:D013088 Spermatocele Ethinyl Estradiol 17.3816709447
MESH:D013088 Spermatocele Phenol 17.3818646496
MESH:D013088 Spermatocele Tamoxifen 17.3816709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.7119457130
MESH:D013119 Spinal Cord Injuries zileuton 9.7118059327
MESH:D013274 Stomach Neoplasms decitabine 2.4019037991
MESH:D013274 Stomach Neoplasms Tretinoin 2.4017261132
MESH:D013276 Stomach Ulcer Thalidomide 3.7615138204
MESH:D019966 Substance-Related Disorders bisphenol A 3.5016045194 16684133
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.1711994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7415669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4112697716
MESH:D013964 Thyroid Neoplasms decitabine 6.0617967635
MESH:D013964 Thyroid Neoplasms Tretinoin 6.0616026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.3616051514
MESH:D014277 Trigeminal Neuralgia Phenol 5.9510223447 16527771
MESH:D014376 Tuberculosis Tretinoin 2.9116040207
MESH:D001749 Urinary Bladder Neoplasms decitabine 4.4919087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 4.498653321 16712894 17572228
MESH:D014581 Urticaria Acetaminophen 2.5310982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.2616129372
MESH:D014591 Uterine Diseases bisphenol A 4.5114652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8414692618
MESH:D014604 Uveal Neoplasms decitabine 11.1717785578
MESH:D014604 Uveal Neoplasms Tretinoin 11.1716752155
MESH:D014605 Uveitis Cyclosporine 3.491336536
MESH:D014652 Vascular Diseases Thalidomide 4.9915741222
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1012125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1014671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.5916761959
MESH:D014860 Warts Phenol 5.6019122958
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7515886252
MESH:D015430 Weight Gain Dietary Fats 3.3316723640
MESH:D009396 Wilms Tumor Tretinoin 3.5616287080
MESH:D014985 Xerophthalmia Cyclosporine 3.9417120751
Pathway ID Pathway Name
KEGG:04520 Adherens junction
REACT:578 Apoptosis
KEGG:05120 Epithelial cell signaling in Helicobacter pylori infection
KEGG:04540 Gap junction
REACT:11123 Membrane Trafficking
KEGG:04530 Tight junction
KEGG:05110 Vibrio cholerae infection
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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