AutismKB 2.0

Annotation Detail for TNFRSF1A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TNFRSF1A ( CD120a,FPF,MGC19588,TBP1,TNF-R,TNF-R-I,TNF-R55,TNFAR,TNFR1,TNFR55,TNFR60,p55,p55-R,p60 )
Gene Full Name: tumor necrosis factor receptor superfamily, member 1A
Band: 12p13.31
Quick LinksEntrez ID:7132; OMIM: 191190; Uniprot ID:TNR1A_HUMAN; ENSEMBL ID: ENSG00000067182; HGNC ID: 11916
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04920Adipocytokine signaling pathway
hsa05160Hepatitis C
hsa04010MAPK signaling pathway
hsa05142Chagas disease
hsa05145Toxoplasmosis
hsa05014Amyotrophic lateral sclerosis (ALS)
hsa05010Alzheimer's disease
hsa04060Cytokine-cytokine receptor interaction
hsa04210Apoptosis
Pathway IDPathway Name
Apoptosis
Pathway IDPathway Name
200070Signaling events mediated by HDAC Class I
200133HIV-1 Nef: Negative effector of Fas and TNF-alpha
200086TNF receptor signaling pathway
200148Caspase cascade in apoptosis
200026Canonical NF-kappaB pathway
200100Ceramide signaling pathway
Pathway IDPathway Name
P00006Apoptosis signaling pathway
Pathway IDPathway Name
500256TNF signaling
Related Diseases/Disorders Top
No data
No data
Desease Name
rheumatoid arthritis
cystic fibrosis
CARDIOVASCULAR
myocardial infarct
diabetes, type 1
tuberculosis tumor necrosis factor-alpha
lymphoma
CANCER
Tumor necrosis factor receptor-associated periodic syndrome
ulcerative colitis
obesity PAI-1 levels
multiple sclerosis
amyloidosis
carotid intima-media thickness
IMMUNE
Behcet's Disease
METABOLIC
lung cancer
Crohn's disease
thrombosis, deep vein
diabetes, type 2
INFECTION
Desease Name
Multiple sclerosis
Desease Name
Periodic fever, familial
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C038983 1,3-dimethylthiourea 1,3-dimethylthiourea inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
C038983 1,3-dimethylthiourea 1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
C047948 1'-acetoxychavicol acetate 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 15905586
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of TNFRSF1A mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of TNFRSF1A mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of TNFRSF1A mRNAdecreases expression 18648102
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal results in decreased expression of TNFRSF1A mRNAdecreases expression 12419474
D000082 Acetaminophen Acetaminophen affects the expression of TNFRSF1A mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased expression of TNFRSF1A mRNAincreases expression 12540782
14557383
D000082 Acetaminophen O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [Acetaminophen results in increased expression of TNFRSF1A mRNA]decreases reaction|increases expression 12540782
D000082 Acetaminophen TNFRSF1A protein affects the reaction [Acetaminophen results in increased expression of CTGF mRNA]affects reaction|increases expression 14550746
D000082 Acetaminophen TNFRSF1A protein affects the reaction [Acetaminophen results in increased expression of MMP9 mRNA]affects reaction|increases expression 14550746
D000082 Acetaminophen TNFRSF1A protein affects the reaction [Acetaminophen results in increased expression of TNF mRNA]affects reaction|increases expression 14557383
D000082 Acetaminophen TNFRSF1A protein affects the reaction [Acetaminophen results in increased expression of TNF protein]affects reaction|increases expression 14557383
D000082 Acetaminophen TNFRSF1A protein affects the reaction [pimagedine inhibits the reaction [NOS2 protein results in increased susceptibility to Acetaminophen]]affects reaction|decreases reaction|increases response to substance 14550746
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of CCL2 mRNA]increases expression|increases reaction 14557383
14550746
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of CCL2 protein]increases expression|increases reaction 14557383
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of CCL3 mRNA]increases expression|increases reaction 14557383
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of CCL3 protein]increases expression|increases reaction 14557383
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of CXCL2 mRNA]increases expression|increases reaction 14557383
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of CXCL2 protein]increases expression|increases reaction 14557383
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of ICAM1 mRNA]increases expression|increases reaction 14557383
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of IFNG mRNA]increases expression|increases reaction 14557383
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of IL10 mRNA]increases expression|increases reaction 14550746
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of IL1A mRNA]increases expression|increases reaction 14557383
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of IL1B mRNA]increases expression|increases reaction 14557383
14550746
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of IL6 mRNA]increases expression|increases reaction 14557383
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of NOS2 mRNA]increases expression|increases reaction 14557383
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of SELE mRNA]increases expression|increases reaction 14557383
D000082 Acetaminophen TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of VCAM1 mRNA]increases expression|increases reaction 14557383
D000082 Acetaminophen TNFRSF1A protein results in decreased susceptibility to Acetaminophendecreases response to substance 14550746
D000082 Acetaminophen TNFRSF1A protein results in decreased susceptibility to [Acetaminophen results in increased expression of NOS2 protein]decreases response to substance|increases expression 14550746
D000082 Acetaminophen TNFRSF1A protein results in increased susceptibility to Acetaminophenincreases response to substance 14557383
D015081 2-Naphthylamine 2-Naphthylamine results in decreased expression of TNFRSF1A mRNAdecreases expression 18247414
D000967 Antimony Sodium Gluconate Antimony Sodium Gluconate results in decreased expression of TNFRSF1A proteindecreases expression 7844400
D016718 Arachidonic Acid TNFRSF1A protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]]affects reaction|decreases reaction|increases abundance 10588948
D001151 Arsenic Arsenic results in decreased expression of TNFRSF1A mRNAdecreases expression 11134558
C006632 arsenic trioxide arsenic trioxide results in increased expression of TNFRSF1A mRNAincreases expression 20458559
C015001 arsenite arsenite results in increased expression of TNFRSF1A mRNAincreases expression 18585952
C015001 arsenite XPA protein affects the reaction [arsenite results in increased expression of TNFRSF1A mRNA]affects reaction|increases expression 18585952
D001194 Asbestos Asbestos results in increased expression of TNFRSF1Aincreases expression 18709470
C065179 atorvastatin atorvastatin results in decreased expression of TNFRSF1A proteindecreases expression 16360360
D001554 Benzene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of TNFRSF1A mRNAaffects cotreatment|decreases expression 17905399
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A proteinaffects cotreatment|increases expression 21295105
D019324 beta-Naphthoflavone isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein]affects cotreatment|decreases reaction|increases expression 21295105
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of TNFRSF1A mRNAdecreases expression 18247414
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of TNFRSF1A mRNAincreases expression 15735009
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of TNFRSF1A mRNAaffects expression 20382639
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TNFRSF1A mRNAdecreases expression 19150397
C026609 beta-solamarine beta-solamarine results in increased expression of TNFRSF1A proteinincreases expression 17619073
C095105 bexarotene bexarotene results in increased expression of TNFRSF1A mRNAincreases expression 16648578
C024626 bradykinin, des-Arg(9)- TNFRSF1A protein promotes the reaction [bradykinin, des-Arg(9)- results in increased expression of BDKRB1 protein]increases expression|increases reaction 16039549
D002083 Butylated Hydroxyanisole TNFRSF1A protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]]affects reaction|decreases reaction|increases abundance 10588948
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of TNFRSF1A mRNAdecreases expression 12419474
C006862 butylphen butylphen results in increased expression of TNFRSF1A proteinincreases expression 15816839
D002101 Cacodylic Acid Cacodylic Acid results in decreased expression of TNFRSF1A mRNAdecreases expression 17481689
C058819 calphostin C calphostin C inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
C058819 calphostin C calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of TNFRSF1A mRNAaffects expression 15963342
D002251 Carbon Tetrachloride [Carbon Tetrachloride co-treated with TM4SF4 protein] results in increased expression of TNFRSF1A mRNAaffects cotreatment|increases expression 17069928
D002251 Carbon Tetrachloride [Carbon Tetrachloride co-treated with TM4SF4 protein] results in increased expression of TNFRSF1A proteinaffects cotreatment|increases expression 17069928
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of TNFRSF1A mRNAincreases expression 17522070
D002725 Chloroform Chloroform results in increased expression of TNFRSF1A mRNAincreases expression 17522070
D002784 Cholesterol Cholesterol analog results in increased expression of TNFRSF1A proteinincreases expression 19477266
D003042 Cocaine Cocaine affects the expression of TNFRSF1A mRNAaffects expression 15681117
D003078 Colchicine TNFRSF1A protein affects the susceptibility to Colchicineaffects response to substance 20159942
D003474 Curcumin Curcumin inhibits the reaction [TNF protein results in increased expression of TNFRSF1A mRNA]decreases reaction|increases expression 17666914
D003474 Curcumin Curcumin inhibits the reaction [TNF protein results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 17666914
D003634 DDT DDT results in decreased expression of TNFRSF1A mRNAdecreases expression 11948501
D003634 DDT DDT results in increased expression of TNFRSF1A mRNAincreases expression 11948501
D003907 Dexamethasone Dexamethasone results in decreased expression of TNFRSF1A mRNAdecreases expression 17522070
D002945 Cisplatin Cisplatin results in increased expression of TNFRSF1A proteinincreases expression 15701814
D002945 Cisplatin SB 203580 inhibits the reaction [Cisplatin results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 15701814
D002945 Cisplatin TNFRSF1A protein affects the susceptibility to Cisplatinaffects response to substance 20159942
D004040 Dietary Carbohydrates Dietary Carbohydrates results in decreased expression of TNFRSF1A mRNAdecreases expression 17490981
D004041 Dietary Fats Dietary Fats results in decreased expression of TNFRSF1A mRNAdecreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A proteinaffects cotreatment|increases expression 21295105
D004052 Diethylnitrosamine isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein]affects cotreatment|decreases reaction|increases expression 21295105
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of TNFRSF1A proteinincreases expression 15798949
D004121 Dimethyl Sulfoxide Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
D004121 Dimethyl Sulfoxide Dimethyl Sulfoxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
D004317 Doxorubicin Doxorubicin results in increased expression of TNFRSF1A proteinincreases expression 17651020
D004391 Dust Dust results in increased expression of TNFRSF1A mRNAincreases expression 17805423
D004918 Erythromycin Estolate Erythromycin Estolate results in increased expression of TNFRSF1A mRNAincreases expression 17522070
D004958 Estradiol Estradiol results in increased expression of TNFRSF1A mRNAincreases expression 12469912
D005047 Etoposide TNFRSF1A protein affects the susceptibility to Etoposideaffects response to substance 20159942
D005665 Furosemide Furosemide affects the expression of TNFRSF1A mRNAaffects expression 17497460
D005978 Glutathione TNFRSF1A protein affects the abundance of Glutathioneaffects abundance 20159942
D006581 Hexachlorobenzene Hexachlorobenzene results in increased expression of TNFRSF1A mRNAincreases expression 15159207
D006861 Hydrogen Peroxide 1,3-dimethylthiourea inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
D006861 Hydrogen Peroxide calphostin C inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
D006861 Hydrogen Peroxide CAT protein inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
D006861 Hydrogen Peroxide Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of TNFRSF1A proteinincreases expression 9870925
D006861 Hydrogen Peroxide KB R8301 inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
D006861 Hydrogen Peroxide TNFRSF1A protein affects the susceptibility to Hydrogen Peroxideaffects response to substance 20159942
D007213 Indomethacin TNFRSF1A protein affects the susceptibility to Indomethacinaffects response to substance 15138204
D007530 Isoflurane Isoflurane results in decreased expression of TNFRSF1A mRNAdecreases expression 16978161
C016527 isoquercitrin isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein]affects cotreatment|decreases reaction|increases expression 21295105
C423012 KB R8301 KB R8301 inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
C423012 KB R8301 KB R8301 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
C467567 lenalidomide lenalidomide results in decreased expression of TNFRSF1A mRNAdecreases expression 15618473
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of TNFRSF1A proteinincreases expression 10072544
D008070 Lipopolysaccharides NFKBIA protein inhibits the reaction [Lipopolysaccharides results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 10072544
D008070 Lipopolysaccharides Magnesium deficiency promotes the reaction [Lipopolysaccharides results in increased expression of TNFRSF1A mRNA]increases expression|increases reaction 13679239
D008274 Magnesium Magnesium deficiency promotes the reaction [Lipopolysaccharides results in increased expression of TNFRSF1A mRNA]increases expression|increases reaction 13679239
C030957 methylmercury II [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of TNFRSF1A mRNAaffects cotreatment|decreases expression 17905399
D015735 Mifepristone Mifepristone results in increased expression of TNFRSF1A mRNAincreases expression 17584828
C020300 monomethylarsonic acid monomethylarsonic acid results in decreased expression of TNFRSF1A mRNAdecreases expression 17481689
D009151 Mustard Gas TNF protein affects the reaction [Mustard Gas affects the expression of TNFRSF1A mRNA]affects expression|affects reaction 16173061
D009270 Naloxone Naloxone results in decreased expression of TNFRSF1A mRNAdecreases expression 17522070
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of TNFRSF1A mRNAincreases expression 15913567
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of TNFRSF1A mRNAincreases expression 17522070
D009538 Nicotine Nicotine results in decreased expression of TNFRSF1A mRNAdecreases expression 18247414
C107010 O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [Acetaminophen results in increased expression of TNFRSF1A mRNA]decreases reaction|increases expression 12540782
D010126 Ozone IL1R1 gene mutant form inhibits the reaction [Ozone results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 17575079
D010126 Ozone IL6 gene mutant form inhibits the reaction [Ozone results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 15516495
D010126 Ozone Ozone affects the expression of TNFRSF1A mRNAaffects expression 11159038
D010126 Ozone Ozone results in increased expression of TNFRSF1A proteinincreases expression 16002559
17575079
15516495
D010126 Ozone TNFRSF1A protein affects the reaction [Ozone affects the expression of TNFRSF1B mRNA]affects expression|affects reaction 11159038
D010126 Ozone TNFRSF1B protein affects the reaction [Ozone affects the expression of TNFRSF1A mRNA]affects expression|affects reaction 11159038
D017239 Paclitaxel TNFRSF1A protein affects the susceptibility to Paclitaxelaffects response to substance 20159942
C041786 palm oil palm oil results in decreased expression of TNFRSF1A mRNAdecreases expression 18042831
D010424 Pentobarbital Pentobarbital results in decreased expression of TNFRSF1A mRNAdecreases expression 16978161
C004479 pimagedine TNFRSF1A protein affects the reaction [pimagedine inhibits the reaction [NOS2 protein results in increased susceptibility to Acetaminophen]]affects reaction|decreases reaction|increases response to substance 14550746
D011802 Quinidine Quinidine results in decreased expression of TNFRSF1A mRNAdecreases expression 17522070
C093642 SB 203580 SB 203580 inhibits the reaction [Cisplatin results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 15701814
C017947 sodium arsenite sodium arsenite results in decreased expression of TNFRSF1A mRNAdecreases expression 16014739
C017947 sodium arsenite sodium arsenite results in increased expression of TNFRSF1A mRNAincreases expression 14691202
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of TNFRSF1A mRNAincreases expression 15310856
12167310
14718646
D013749 Tetrachlorodibenzodioxin TNFRSF1A protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of INSR protein]affects reaction|decreases expression 20181658
D013749 Tetrachlorodibenzodioxin TNFRSF1A protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of IRS1 protein]affects reaction|decreases expression 20181658
D013749 Tetrachlorodibenzodioxin TNFRSF1A protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC2A4 protein]affects reaction|decreases expression 20181658
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of TNFRSF1A mRNAincreases expression 16054898
D013752 Tetracycline Tetracycline results in increased expression of TNFRSF1A mRNAincreases expression 17522070
D013755 Tetradecanoylphorbol Acetate 1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
D013755 Tetradecanoylphorbol Acetate calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
D013755 Tetradecanoylphorbol Acetate Dimethyl Sulfoxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
D013755 Tetradecanoylphorbol Acetate KB R8301 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]decreases reaction|increases expression 9870925
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in decreased expression of TNFRSF1A proteindecreases expression 11882518
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A proteinincreases expression 9870925
D013792 Thalidomide Thalidomide results in decreased expression of TNFRSF1A mRNAdecreases expression 15618473
D013792 Thalidomide Thalidomide results in decreased expression of TNFRSF1A proteindecreases expression 16344495
D014212 Tretinoin Tretinoin results in increased expression of TNFRSF1A mRNAincreases expression 18230668
D014212 Tretinoin [Tretinoin co-treated with zoledronic acid] results in increased expression of TNFRSF1A mRNAaffects cotreatment|increases expression 20349282
D014212 Tretinoin Tretinoin results in increased expression of TNFRSF1A mRNAincreases expression 16166294
D014241 Trichloroethylene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of TNFRSF1A mRNAaffects cotreatment|decreases expression 17905399
C025643 vinclozolin vinclozolin results in increased expression of TNFRSF1A mRNAincreases expression 18629315
C403304 zerumbone zerumbone inhibits the reaction [TNFRSF1A protein results in increased activity of [NFKB1 protein binds to RELA protein]]affects binding|decreases reaction|increases activity 16007145
C088658 zoledronic acid [Tretinoin co-treated with zoledronic acid] results in increased expression of TNFRSF1A mRNAaffects cotreatment|increases expression 20349282
C088658 zoledronic acid zoledronic acid results in increased expression of TNFRSF1A mRNAincreases expression 19036117
D015054 Zymosan Zymosan results in increased expression of TNFRSF1A proteinincreases expression 10072544
D015054 Zymosan TNFRSF1A gene mutant form inhibits the reaction [Zymosan results in decreased expression of BCL2 protein]decreases expression|decreases reaction 17724436
D015054 Zymosan TNFRSF1A gene mutant form inhibits the reaction [Zymosan results in increased activity of MPO protein]decreases reaction|increases activity 17724436
D015054 Zymosan TNFRSF1A gene mutant form inhibits the reaction [Zymosan results in increased expression of BAX protein]decreases reaction|increases expression 17724436
D015054 Zymosan TNFRSF1A gene mutant form inhibits the reaction [Zymosan results in increased expression of FASL protein]decreases reaction|increases expression 17724436
D015054 Zymosan TNFRSF1A gene mutant form inhibits the reaction [Zymosan results in increased expression of IL1B protein]decreases reaction|increases expression 17724436
D015054 Zymosan TNFRSF1A gene mutant form inhibits the reaction [Zymosan results in increased expression of IL6 protein]decreases reaction|increases expression 17724436
D015054 Zymosan TNFRSF1A gene mutant form inhibits the reaction [Zymosan results in increased expression of NOS2 protein]decreases reaction|increases expression 17724436
D015054 Zymosan TNFRSF1A gene mutant form inhibits the reaction [Zymosan results in increased expression of TGFB1 protein]decreases reaction|increases expression 17724436
D015054 Zymosan TNFRSF1A gene mutant form inhibits the reaction [Zymosan results in increased expression of TNF protein]decreases reaction|increases expression 17724436
D015054 Zymosan TNFRSF1A gene mutant form inhibits the reaction [Zymosan results in increased expression of VEGFA protein]decreases reaction|increases expression 17724436
D015054 Zymosan TNFRSF1A protein affects the susceptibility to Zymosanaffects response to substance 10890648
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.1715322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Thalidomide 6.178333272
MESH:D058186 Acute Kidney Injury Cisplatin 6.7912690470 15814532 17670903
MESH:D058186 Acute Kidney Injury zoledronic acid 6.7919715164
MESH:D055371 Acute Lung Injury Lipopolysaccharides 3.3211850527 18653653
MESH:D000210 Acute-Phase Reaction zoledronic acid 4.7020200999
MESH:D000230 Adenocarcinoma arsenic trioxide 16.5219825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 16.5220127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 16.5217638652 11798837
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 16.5216033868
MESH:D000230 Adenocarcinoma Doxorubicin 16.5217418594
MESH:D000230 Adenocarcinoma Estradiol 16.5211473722
MESH:D000230 Adenocarcinoma Indomethacin 16.5216537180
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 23.903712494
MESH:D000236 Adenoma Benzo(a)pyrene 23.906695378
MESH:D000236 Adenoma beta-Naphthoflavone 23.9019389873
MESH:D000236 Adenoma Diethylnitrosamine 23.9010737359 6695378
MESH:D000236 Adenoma Dimethylnitrosamine 23.9019555203
MESH:D000236 Adenoma Indomethacin 23.9011497255
MESH:D000236 Adenoma Magnesium 23.9017823441
MESH:D018248 Adenoma, Liver Cell DDT 13.0512597452
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 13.0517162532 19052882 17620307 19061943 18056438 16434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 13.0516835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.9115276417
MESH:D018246 Adrenocortical Adenoma Arsenic 11.1717306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 11.1716712894 17306315
MESH:D000382 Agricultural Workers' Diseases DDT 3.9416487989 12584743
MESH:D000419 Albuminuria Doxorubicin 3.8021441931
MESH:D019973 Alcohol-Related Disorders Curcumin 4.2917887948
MESH:D000505 Alopecia Tretinoin 2.9815955085
MESH:D016301 Alveolar Bone Loss Indomethacin 4.5817225004
MESH:D000544 Alzheimer Disease Curcumin 7.3615590663
MESH:D000544 Alzheimer Disease Indomethacin 7.3615579461 17627676
MESH:D000544 Alzheimer Disease Nicotine 7.3616627626
MESH:D000544 Alzheimer Disease Ozone 7.3615513908
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 10.4810965797
MESH:D000690 Amyotrophic Lateral Sclerosis lenalidomide 10.4816510725
MESH:D000690 Amyotrophic Lateral Sclerosis Thalidomide 10.4816510725
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.7211748828
MESH:D000740 Anemia Zymosan 6.7218664788
MESH:D000741 Anemia, Aplastic Benzene 3.7411369114 14761424 17661222
MESH:D000799 Angioedema Acetaminophen 3.0510982225
MESH:D001008 Anxiety Disorders Pentobarbital 7.1618313124 11141031
MESH:D001008 Anxiety Disorders vinclozolin 7.1619015723
MESH:D001014 Aortic Aneurysm Indomethacin 4.1110231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 9.1919183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 9.1910388637
MESH:D001145 Arrhythmias, Cardiac Quinidine 4.4718057881 18724381
MESH:D020261 Arsenic Poisoning Arsenic 2.5916251483 12569548 16835338 18414634
MESH:D001161 Arteriosclerosis Dietary Fats 3.1315238619
MESH:D018771 Arthralgia Indomethacin 4.382160914
MESH:D001169 Arthritis, Experimental Dexamethasone 13.2717659584
MESH:D001169 Arthritis, Experimental Thalidomide 13.279598899
MESH:D001169 Arthritis, Experimental Tretinoin 13.2716412693
MESH:D001169 Arthritis, Experimental Zymosan 13.2715188379 16872482 15142272 17659584 15944321
MESH:D001172 Arthritis, Rheumatoid Curcumin 8.3816807698
MESH:D001172 Arthritis, Rheumatoid Indomethacin 8.3811248219
MESH:D001172 Arthritis, Rheumatoid Ozone 8.3815570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 8.3816292516
MESH:D001249 Asthma Mustard Gas 6.0710378619
MESH:D001249 Asthma Ozone 6.0717854713 16373670
MESH:D001249 Asthma Tretinoin 6.0716456186
MESH:D050197 Atherosclerosis Arsenic 11.5319371607 12928151
MESH:D050197 Atherosclerosis Asbestos 11.5318795166
MESH:D050197 Atherosclerosis Cholesterol 11.5316632123
MESH:D050197 Atherosclerosis Curcumin 11.5318704882
MESH:D001321 Autistic Disorder Acetaminophen 2.4118445737
MESH:D001321 Autistic Disorder Arachidonic Acid 2.4118582451
MESH:D001321 Autistic Disorder Glutathione 2.4119267885 19056591 18929414 16917939
MESH:D001321 Autistic Disorder Magnesium 2.4116846101
MESH:D001327 Autoimmune Diseases Curcumin 3.7419761891
MESH:D001471 Barrett Esophagus Tretinoin 3.6616935849
MESH:D001477 Bartter Syndrome Indomethacin 4.2210684365
MESH:D001528 Behcet Syndrome Colchicine 5.3515870978
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.2311289319 1440618
MESH:D001768 Blister Mustard Gas 4.3819167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 11.2816206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 11.2812125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 11.2816206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.0015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.2215746008
MESH:D001855 Bone Marrow Diseases Benzene 4.4416183116
MESH:D019046 Bone Marrow Neoplasms Cisplatin 15.8214601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 15.8214601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 15.8214601052
MESH:D001859 Bone Neoplasms Paclitaxel 8.4415867366
MESH:D001859 Bone Neoplasms zoledronic acid 8.4415867366 19442620 16778634 16121404 17312309 11697798
MESH:D001862 Bone Resorption zoledronic acid 4.0018404659 18496637 15845617 16769263 11869084 8053405
MESH:D001929 Brain Edema Indomethacin 4.2311481608
MESH:D002545 Brain Ischemia Curcumin 7.8116770732
MESH:D002545 Brain Ischemia Indomethacin 7.8112524144
MESH:D001932 Brain Neoplasms Curcumin 6.7017596214
MESH:D001932 Brain Neoplasms Doxorubicin 6.7017150277
MESH:D001943 Breast Neoplasms Benzene 18.1717162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 18.1720146248 17474063
MESH:D001943 Breast Neoplasms bexarotene 18.1716818667 16344269
MESH:D001943 Breast Neoplasms Cacodylic Acid 18.1717474063
MESH:D001943 Breast Neoplasms Cisplatin 18.1719526202 18382427
MESH:D001943 Breast Neoplasms Curcumin 18.1718462866 19250217 18593918 16243823
MESH:D001943 Breast Neoplasms DDT 18.1712709520 16792888
MESH:D001943 Breast Neoplasms Dietary Fats 18.1720435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 18.1717474063
MESH:D001943 Breast Neoplasms Doxorubicin 18.1716935488 15668708 16264153 15994142 15939500 19526202 18382427 17983394 15567936 16826403 18695136 16096432 15136595 16322301 17426702 16595493 16115903 15692762 18234424 15993339 11325840 17369602 15634643 18628466
MESH:D001943 Breast Neoplasms Estradiol 18.1712948864 17261762 19861407 17289903 17018787 16675129 14630087 18497071
MESH:D001943 Breast Neoplasms Etoposide 18.1716322251
MESH:D001943 Breast Neoplasms Hexachlorobenzene 18.1712709520 15061365
MESH:D001943 Breast Neoplasms Indomethacin 18.1717401462
MESH:D001943 Breast Neoplasms Paclitaxel 18.1718323546 16244791 11325840 16273361 16115903 15136595 18223236 18234424
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 18.1720435547
MESH:D001943 Breast Neoplasms Tretinoin 18.1716443354 16166294 16873071
MESH:D001943 Breast Neoplasms Trichloroethylene 18.1715986119
MESH:D001943 Breast Neoplasms zoledronic acid 18.1716096432 18695136
MESH:D016535 Bronchial Hyperreactivity Ozone 3.0515516495 14754758 19059883 16777450 17626835 18417511 18315731
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.3815286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.1910378619 17687719
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.8116813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.6011589617
MESH:D002056 Burns Indomethacin 3.9510459503
MESH:D002100 Cachexia Indomethacin 9.8215141370 16537180 15625704 11239499
MESH:D002100 Cachexia Ozone 9.8216183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.6916111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.0316192424 16124888 16227642 16097048 15700767 16011737 10355542 18705752 16050911 15721981 3786805 15673190
MESH:D002276 Carcinoid Tumor Doxorubicin 4.0216051944
MESH:D002277 Carcinoma Curcumin 10.3518593918
MESH:D002277 Carcinoma Dimethylnitrosamine 10.3519555203
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 10.3516835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.0915504454 17687452
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.3716168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 39.4916705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 39.4916705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 39.497296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 39.493084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 39.4916507464 17306315
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 39.4914691202 15553829 15073043 11135700 16217749
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 39.4918788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 39.4917982673
MESH:D006528 Carcinoma, Hepatocellular DDT 39.4912597452
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 39.4918210153 10672840 19822196 20524982 18393292 19107877 19171122 20727157 20007298 18785209 17173139 19418558 19701751 16502159 17978847 20514400 3084413 18056438 19052882 20214788 18506893 19919837 16288022 17055752 19539802 3581430 17761372 19335982 16779866 19394651 17138121 20512989 21159647 18971187 18494052 19208518 16328049 18788625 20432363 20101231 19519916 18665156 16569478 16698587 10737359 18978308 20935162 17428255 11831363 17162532 19383236 16830150 16878318 20084675 18691550 16681979 16935385 16807293 16540662
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 39.4916234567 16023760 17876044 18059187
MESH:D006528 Carcinoma, Hepatocellular Estradiol 39.4916924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 39.4916391822
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 39.4916313753
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 39.4916507464 15276417 17306315
MESH:D006528 Carcinoma, Hepatocellular Thalidomide 39.4916313753
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 39.491917145
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 3.9511053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.5718791128 14736730 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 9.9016247446
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 9.9012023789 16685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 9.9018414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 9.9019233551
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.0819014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 11.817296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 11.811485588 16201981
MESH:D002292 Carcinoma, Renal Cell Indomethacin 11.8117341418
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 11.8118507039
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.4312490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 31.3515504454 18922899 17687452
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 31.3520419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 31.3517066447 18337622 6189445
MESH:D002294 Carcinoma, Squamous Cell Curcumin 31.3518462866
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 31.3516033868
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 31.356189445
MESH:D002294 Carcinoma, Squamous Cell Glutathione 31.3517015178
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 31.3512636206 15482327
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 31.3518572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 31.3518922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 31.3516051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Arsenic 3.3918640142
MESH:D006332 Cardiomegaly atorvastatin 5.5718360054
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.5718670907 16120746 18850075
MESH:D009202 Cardiomyopathies Doxorubicin 6.6116364871 17308081 17007740 16651473 16455267 17924179 16242529 18627295 15811867 15792986 17131338 15505089 16612575 16269455 17351982 17974986 15476868 16109756 17519947 17329180 16278810 17928571 17382496 16952015 16731534
MESH:D009202 Cardiomyopathies pimagedine 6.6116612575
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.6117334414 16243910
MESH:D002318 Cardiovascular Diseases Arsenic 5.6715738583 19152805 17938729
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 5.6716936243
MESH:D002340 Carotid Artery Diseases Arsenic 3.6418022660 16973168
MESH:D002386 Cataract Acetaminophen 9.5410977129
MESH:D002386 Cataract pimagedine 9.5417936468 15003327
MESH:D002386 Cataract Tretinoin 9.5417460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 18.946135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 18.947505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 18.9420889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 18.9421159647 7505956 2727394 17174075
MESH:D002471 Cell Transformation, Neoplastic Estradiol 18.9418566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 18.9420056578 19524636
MESH:D002524 Cerebellar Ataxia Antimony Sodium Gluconate 5.8216432602
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.8116129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 12.3319052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 12.3316835633
MESH:D018281 Cholangiocarcinoma Thalidomide 12.3318291259
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 5.4112912871
MESH:D002764 Cholecystitis Indomethacin 4.3811181007
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 6.3818590720 15500046 12927374 19486331 16629650 7624871 18164287 15913567
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 6.3819486331 9022650
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 5.0619407337 10220858
MESH:D002822 Choriocarcinoma Tretinoin 4.3716461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.4315668235 16354765 12621046 15340226 8697196
MESH:D002972 Cleft Palate Tretinoin 4.439407595
MESH:D019970 Cocaine-Related Disorders Cocaine 4.9419606084
MESH:D003092 Colitis Curcumin 11.8416804969 18200517 16782535
MESH:D003092 Colitis Thalidomide 11.8416680017
MESH:D003092 Colitis Tretinoin 11.8417035595
MESH:D003103 Coloboma Curcumin 3.8418809619
MESH:D003110 Colonic Neoplasms arsenite 6.5215037631
MESH:D003110 Colonic Neoplasms Curcumin 6.5219359593 16340194
MESH:D003110 Colonic Neoplasms Dexamethasone 6.5215824018
MESH:D003110 Colonic Neoplasms Indomethacin 6.5215936596 15786552 15963497 15625704 15637740 11260862
MESH:D003111 Colonic Polyps Magnesium 5.3117823441
MESH:D015179 Colorectal Neoplasms arsenic trioxide 6.7620501625
MESH:D015179 Colorectal Neoplasms Cisplatin 6.7615273666
MESH:D015179 Colorectal Neoplasms Doxorubicin 6.7618802399 18259882
MESH:D015179 Colorectal Neoplasms Indomethacin 6.7612606626 11197048 17054584 18059344
MESH:D015179 Colorectal Neoplasms Magnesium 6.7617823441
MESH:D015179 Colorectal Neoplasms Paclitaxel 6.7618802399
MESH:D000013 Congenital Abnormalities DDT 7.2415095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.2417141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 10.0818497527
MESH:D016510 Corneal Neovascularization Thalidomide 10.089301478
MESH:D003324 Coronary Artery Disease atorvastatin 3.8016368305
MESH:D023903 Coronary Restenosis arsenic trioxide 3.4412609071
MESH:D018352 Coronavirus Infections Indomethacin 4.9217302372
MESH:D003389 Cranial Nerve Diseases Thalidomide 5.519200351
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 7.6210525206
MESH:D019465 Craniofacial Abnormalities Benzene 7.6215643154
MESH:D019465 Craniofacial Abnormalities Dexamethasone 7.6217728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 7.6215322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Thalidomide 7.629200351
MESH:D019465 Craniofacial Abnormalities Tretinoin 7.629142499 9224671 16925845 17551590 9211117 14991402 9664655 10589399 9125849 8800419
MESH:D003424 Crohn Disease Thalidomide 3.7216078585
MESH:D003456 Cryptorchidism vinclozolin 3.6014966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 8.3818551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 8.3818551238
MESH:D003550 Cystic Fibrosis marker/mechanism 16463024
MESH:D003550 Cystic Fibrosis Glutathione 3.8119747007
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.3715213294
MESH:D003872 Dermatitis Benzene 4.0115902427
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 4.632524372 11298694 14531868 8970840 11906362 8156756 18759878 12868966
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 4.6312438553
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 2.782952479 3621924
MESH:D002658 Developmental Disabilities Magnesium 4.3416846101
MESH:D003921 Diabetes Mellitus, Experimental therapeutic 12193562
MESH:D003924 Diabetes Mellitus, Type 2 marker/mechanism 11882518
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 5.5318403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 5.5320387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 5.5317107852
MESH:D003928 Diabetic Nephropathies Curcumin 6.8218204486
MESH:D003928 Diabetic Nephropathies Estradiol 6.8219279558
MESH:D003967 Diarrhea Dexamethasone 5.867237001
MESH:D003967 Diarrhea Indomethacin 5.867237001 7907874
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 39.4818289764 17522070 20133375 7624871
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 39.4818551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 39.4821346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 39.489022650 18648102 18692083 11289319 18289764 9328219 16192314 6482804 1440618 7440962 6679447 9653073 8291058
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 39.4819164858 17522070 19420014 14550746 16393943 11421492 17562736 11529661 12958197 10663392 15619225 11461765 19923254 16109766 12392966 19739265 16485898 15968718 2444490 16081117 19085960 11739529 16227642 10915739 14986274 12540782 16177239 12153990 12594235 12705907 19370779 14725611 10774834 11287661 11834606 18071297 16781746 19416960 11743745 18713872 17906064
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 39.487179309 15998439 10915739 3732212 15027814 4309450 10092053 21278145 6884620 9327722 2869522 16227642 6623471 19336974 7120509 7440962 17522070 19085960 15968718 16177239 11566570 3786805
MESH:D056486 Drug-Induced Liver Injury Chloroform 39.487440962 3732212 17522070 2862719 7120509 6884620 3104120 6623471
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 39.4819107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 39.488172417
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 39.4817416283
MESH:D056486 Drug-Induced Liver Injury Erythromycin Estolate 39.4814998559 17522070
MESH:D056486 Drug-Induced Liver Injury O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate 39.4812540782
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 39.4820420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 39.4817522070
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 39.487120509
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.3119426721
MESH:D004362 Drug Toxicity Cisplatin 10.2619839026 15033597 12231392 12649298
MESH:D004362 Drug Toxicity Doxorubicin 10.2618602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 10.2611462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.3718043480 16326151 16133044 18446180 17190690 12774134
MESH:D004381 Duodenal Ulcer Curcumin 6.9817351913
MESH:D004381 Duodenal Ulcer Indomethacin 6.9817045617 11595415 16699067 17329845 17351913 10671773 11535926 11991626 11595431 17202747 17151854
MESH:D050171 Dyslipidemias Dietary Fats 2.8618367378
MESH:D004417 Dyspnea DDT 8.3116487989
MESH:D004417 Dyspnea Furosemide 8.3116935035
MESH:D020821 Dystonic Disorders Nicotine 5.1517881519
MESH:D004485 Eczema Dexamethasone 3.7212438553
MESH:D004487 Edema Arachidonic Acid 26.167990266 16716910 9599246 9831321 15177302 11698051
MESH:D004487 Edema Dexamethasone 26.1619703484
MESH:D004487 Edema Furosemide 26.1611834646
MESH:D004487 Edema Indomethacin 26.167907874 8985016 19703484 7990266 10653021 8273558 16100529
MESH:D004487 Edema Mustard Gas 26.1611428647 11428631 9260866 11402378
MESH:D004487 Edema Tetrachlorodibenzodioxin 26.1612711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 26.1611698051 15177302 8113982 9599246 7812673 16716910 8273558
MESH:D004487 Edema Zymosan 26.167907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.3215322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 9.3218230668
MESH:D018159 Endolymphatic Hydrops Dimethyl Sulfoxide 5.7720641076
MESH:D016889 Endometrial Neoplasms Doxorubicin 9.2617359293
MESH:D016889 Endometrial Neoplasms Estradiol 9.2619148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Tretinoin 9.2616569247
MESH:D004715 Endometriosis Indomethacin 11.4315652904
MESH:D004715 Endometriosis Mifepristone 11.4316134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 11.4310568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.3618037988
MESH:D019446 Endotoxemia Indomethacin 8.0818509659
MESH:D019446 Endotoxemia Lipopolysaccharides 8.0817637181 15328337 15821434
MESH:D004751 Enteritis Indomethacin 3.9616328016 10567023 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.2217980183
MESH:D004802 Eosinophilia Indomethacin 3.3111298111
MESH:D004832 Epilepsy, Absence Naloxone 4.586254150
MESH:D004890 Erythema Mustard Gas 4.389357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.3216302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 20.163581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 20.1620426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 20.1612903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 20.1616530937
MESH:D004938 Esophageal Neoplasms Cisplatin 20.1616785472 16481741 15173087 15464296 17638652
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 20.1617016578
MESH:D004938 Esophageal Neoplasms Indomethacin 20.1611005569
MESH:D004938 Esophageal Neoplasms Paclitaxel 20.1616481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.8011564622
MESH:D005124 Eye Abnormalities Tretinoin 6.809664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 26.3415073043
MESH:D005234 Fatty Liver arsenite 26.3418296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 26.3416239168 16045604 12795759 61145 12631006 19224547 15959796 17595544
MESH:D005234 Fatty Liver Curcumin 26.3419297423
MESH:D005234 Fatty Liver Dietary Fats 26.3419551842 17967931 18296743 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 26.3421071580 20387270
MESH:D005234 Fatty Liver Tetracycline 26.3419224547 16917069
MESH:D005264 Femoral Fractures zoledronic acid 5.0516234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.7011858732
MESH:D005334 Fever marker/mechanism 11175303
MESH:D005334 Fever Arachidonic Acid 11.4511852909
MESH:D005334 Fever Indomethacin 11.4517627676 10431976 11852909
MESH:D005334 Fever Lipopolysaccharides 11.4511852909 9205823
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.236705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 3.8119069698
MESH:D005354 Fibrosarcoma Indomethacin 4.1210962813
MESH:D005355 Fibrosis arsenite 30.0218296743
MESH:D005355 Fibrosis Carbon Tetrachloride 30.0218705752
MESH:D005355 Fibrosis Curcumin 30.0218705752
MESH:D005355 Fibrosis Dietary Fats 30.0218296743
MESH:D005355 Fibrosis Indomethacin 30.0217994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 30.0220067830
MESH:D005355 Fibrosis Tretinoin 30.0217994277
MESH:D005499 Folliculitis Indomethacin 4.3811298111
MESH:D005534 Foot Diseases Arsenic 4.776392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.5216904648
MESH:D005756 Gastritis Acetaminophen 8.5316983495
MESH:D005756 Gastritis Indomethacin 8.5315046732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.9418462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.1616973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.5116417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 3.9016452187
MESH:D005871 Giant Lymph Node Hyperplasia Thalidomide 5.5112701121
MESH:D005909 Glioblastoma Curcumin 12.4517596214
MESH:D005909 Glioblastoma Doxorubicin 12.4517150277
MESH:D005909 Glioblastoma Indomethacin 12.4512870263
MESH:D005909 Glioblastoma Tretinoin 12.4517312396
MESH:D005910 Glioma Indomethacin 5.3116487511 18371953
MESH:D005910 Glioma Thalidomide 5.3116327979
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.6411849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.317505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.8010696789
MESH:D006073 Gout Indomethacin 4.5711248219
MESH:D006258 Head and Neck Neoplasms Cisplatin 18.2115102660 15464296
MESH:D006258 Head and Neck Neoplasms Curcumin 18.2118462866 18829502
MESH:D006258 Head and Neck Neoplasms Doxorubicin 18.2115692506
MESH:D006258 Head and Neck Neoplasms Indomethacin 18.2115482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 18.2116096774
MESH:D034381 Hearing Loss Cisplatin 12.9019898482
MESH:D034381 Hearing Loss Dimethyl Sulfoxide 12.9020641076
MESH:D034381 Hearing Loss Furosemide 12.9017868369
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.3716084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.7615464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 8.3220471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 8.3210048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 8.3214991402 9664655
MESH:D006331 Heart Diseases Antimony Sodium Gluconate 6.4411049798
MESH:D006331 Heart Diseases Doxorubicin 6.4416707910 17875725 16330681 16495754 14766674 16244372 16244371 18006777 12587719 16879835 17888722 18674790 16144979
MESH:D006333 Heart Failure marker/mechanism 16360360
MESH:D006333 Heart Failure atorvastatin 9.1116360360
MESH:D006333 Heart Failure Doxorubicin 9.1117481944
MESH:D006333 Heart Failure Furosemide 9.1116011733 12660669 16845234
MESH:D006394 Hemangiosarcoma Doxorubicin 3.2015692506
MESH:D006402 Hematologic Diseases Benzene 3.9316183116
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.6916366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.6311000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 3.8615633222
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 21.6018590720
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 21.606705139
MESH:D006505 Hepatitis Carbon Tetrachloride 21.6019900420 19110552
MESH:D006505 Hepatitis DDT 21.6016487989
MESH:D006505 Hepatitis Zymosan 21.6019110552
MESH:D019698 Hepatitis C, Chronic Indomethacin 3.9415135802
MESH:D006529 Hepatomegaly DDT 6.412387028
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.4116120746 12621046 15340226
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.2817701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.737520565
MESH:D006558 Herpes Genitalis Estradiol 4.2415709030
MESH:D006561 Herpes Simplex Etoposide 3.8010809021
MESH:D006689 Hodgkin Disease Cisplatin 12.1116170182 16200630
MESH:D006689 Hodgkin Disease Doxorubicin 12.1115147373 17606976 18501091
MESH:D006689 Hodgkin Disease Etoposide 12.1116200630 16135485 18180244 15147373 17606976
MESH:D006689 Hodgkin Disease sodium arsenite 12.1112676792
MESH:D019584 Hot Flashes Estradiol 2.9717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.258697196 18606429 16354765 15340226 16959395
MESH:D006930 Hyperalgesia Acetaminophen 13.5216870215
MESH:D006930 Hyperalgesia Indomethacin 13.5212727271
MESH:D006930 Hyperalgesia Tretinoin 13.5216870215
MESH:D006930 Hyperalgesia zoledronic acid 13.5216769263
MESH:D034321 Hyperamylasemia Indomethacin 4.9217883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.7516899240
MESH:D006934 Hypercalcemia Furosemide 8.9517652376
MESH:D006934 Hypercalcemia zoledronic acid 8.9519622757 18089816
MESH:D053565 Hypercalciuria Furosemide 4.8717652376
MESH:D006937 Hypercholesterolemia atorvastatin 16.2011583720
MESH:D006937 Hypercholesterolemia Cholesterol 16.2016933029
MESH:D006937 Hypercholesterolemia Curcumin 16.2018704882
MESH:D006937 Hypercholesterolemia Dietary Fats 16.2021332399
MESH:D006940 Hyperemia Indomethacin 4.2312524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.8116778211
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.7717050553
MESH:D006949 Hyperlipidemias Dietary Fats 6.9521332399
MESH:D006949 Hyperlipidemias Indomethacin 6.9517546600
MESH:D006938 Hyperlipoproteinemia Type II atorvastatin 4.5316238680
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 5.0815086907
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.1815034207
MESH:D006973 Hypertension Arsenic 12.429931084 11953799 16076760
MESH:D006973 Hypertension atorvastatin 12.4217042910
MESH:D006973 Hypertension Benzene 12.4217940673
MESH:D006973 Hypertension Dexamethasone 12.4217042910
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 12.4218670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.3315338365
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 4.5316612254
MESH:D006987 Hypesthesia Arsenic 4.7716093927
MESH:D006996 Hypocalcemia zoledronic acid 5.4012669777
MESH:C537153 Hypomagnesemia primary Furosemide 4.8711041285
MESH:D007019 Hypoproteinemia Furosemide 5.0816096441
MESH:D007022 Hypotension Furosemide 7.4811041285
MESH:D007022 Hypotension Isoflurane 7.4812967683
MESH:D007024 Hypotension, Orthostatic Furosemide 4.6315811171
MESH:D007077 Ileal Diseases Indomethacin 4.2310574470 18306037
MESH:D007079 Ileitis Indomethacin 4.5710651667 10647630 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.5816133044
MESH:D007248 Infertility, Male DDT 8.1817157474 17192596
MESH:D007248 Infertility, Male sodium arsenite 8.1815346721 12646999
MESH:D007248 Infertility, Male vinclozolin 8.1816467254
MESH:D007249 Inflammation Arachidonic Acid 38.8015177302 17371808 9831321
MESH:D007249 Inflammation atorvastatin 38.8016908763
MESH:D007249 Inflammation Curcumin 38.8016956363 18403477 17151092
MESH:D007249 Inflammation Dexamethasone 38.8011099482 8960868
MESH:D007249 Inflammation Dietary Fats 38.8020412841
MESH:D007249 Inflammation Diethylnitrosamine 38.8018785209
MESH:D007249 Inflammation Indomethacin 38.807812673 3291741 12568917
MESH:D007249 Inflammation Lipopolysaccharides 38.8017237260 9205823 17963957 12878042 17255318
MESH:D007249 Inflammation Mustard Gas 38.8011428620 17524151 9260866 11402378 11428631 9357497 16001271 8975870 11428647
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 38.8012878042 12200463
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 38.807562506 8273558 11698051 15177302 7812673
MESH:D007249 Inflammation Thalidomide 38.8016134734
MESH:D007249 Inflammation Zymosan 38.808014878 11289658
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.8318596194 18200517
MESH:D007333 Insulin Resistance Dietary Fats 5.5311836018 18457598
MESH:D007333 Insulin Resistance Estradiol 5.5316393666 16627594
MESH:D007410 Intestinal Diseases Indomethacin 12.2911686837 17329856 11855677 11713966 18236018 10210152 15831440 15610444 17994277
MESH:D007410 Intestinal Diseases pimagedine 12.2911713966
MESH:D007410 Intestinal Diseases Tretinoin 12.2917994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.5310783313
MESH:D019586 Intracranial Hypertension Indomethacin 4.5815241188
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 3.9117255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.0617553498
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.238074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.5916580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.5915992940 17551590
MESH:D007579 Jejunal Diseases Indomethacin 4.2316133968 18306037 10574470
MESH:D007642 Keratosis Arsenic 4.2116930632 12749816
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.3515464296
MESH:D007674 Kidney Diseases Acetaminophen 21.1115629191 12587719
MESH:D007674 Kidney Diseases Cisplatin 21.1119839026 18289764 12649298 12231392 15190930
MESH:D007674 Kidney Diseases Doxorubicin 21.1115369732 15699352 16775033
MESH:D007674 Kidney Diseases Estradiol 21.1115618244
MESH:D007674 Kidney Diseases Furosemide 21.1111041285
MESH:D007674 Kidney Diseases Indomethacin 21.1117190690
MESH:D007674 Kidney Diseases sodium arsenite 21.1120008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 7.7916707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 7.7916518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 12.4616705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 12.4616705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 12.466582329
MESH:D007680 Kidney Neoplasms Estradiol 12.4615610895
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.0111231351
MESH:D007859 Learning Disorders Cholesterol 12.2217134702
MESH:D007859 Learning Disorders Colchicine 12.2211749816
MESH:D007859 Learning Disorders DDT 12.227589230
MESH:D007889 Leiomyoma Curcumin 3.8518555241
MESH:D007896 Leishmaniasis Antimony Sodium Gluconate 4.637945751 7960131 20139272 8059918
MESH:D016773 Leishmaniasis, Cutaneous Antimony Sodium Gluconate 6.979770149 15234329 7724530 15678803 10233236 12032913 10617787 10542306 19744259 9234779 1311351 14512915 2160914 10647737 10786029 1314873 8407083 10886148 11528583 9299828 1329273 15610669 2166429 17278657 7570843 9314461 9499605 15259478 1322070 1323630 7682386 20438389
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 6.9712228301 10320625 11703811
MESH:D007897 Leishmaniasis, Mucocutaneous Antimony Sodium Gluconate 5.201325634 1322070 1645930 7519887 16135192 2173461
MESH:D007898 Leishmaniasis, Visceral Antimony Sodium Gluconate 6.7816432602 12379707 12898450 7498017 12718341 10569788 9844051 10467834 17382981 11417033 7844400 11398119 9531339 9665985 15518175 20576500 2098410 10886148 16131481 12870129 8607595 7983993 1319700 1852133 17300636 9756784 15610669 15868188 9856145 1315396 1658990 16117959 15716043 11049798 1314709 10805470 7903366 11751149 8394861 10952587 11069076 11035738 15328135 15896700 9498473 18765878 12803856 1645929 12955641 10617787 1315397 1659303 7715298 7932924 10604050 10603400 17911647 8916804 1337639 9625910
MESH:D007898 Leishmaniasis, Visceral Thalidomide 6.7816514283
MESH:D007938 Leukemia arsenic trioxide 11.2315070760
MESH:D007938 Leukemia Benzene 11.2318335105 15935818 17119257 14694614
MESH:D007938 Leukemia Curcumin 11.2318462866
MESH:D007938 Leukemia Tretinoin 11.2317143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.3616085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 12.3112560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 12.3116106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 12.3118089816
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.5316972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 6.5414633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 6.5416572323 15631656 10785260
MESH:D007951 Leukemia, Myeloid arsenic trioxide 11.9819077051
MESH:D007951 Leukemia, Myeloid Benzene 11.9817506065
MESH:D007951 Leukemia, Myeloid Tretinoin 11.9816482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 9.3417050201 19850784 20471514 16968895 16467208
MESH:D015470 Leukemia, Myeloid, Acute Benzene 9.3419478238
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 9.3418360721
MESH:D015470 Leukemia, Myeloid, Acute Thalidomide 9.3418720364
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 9.3416294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 9.5517339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 9.5516823087 16330433 19642359 16331271 17649720 15336539 9834237 12018890 16891316 15748426 17712046 11468182 16966277 17217047 11161223 16112521 19075265 19035177 15213294 19225113 12679006 17869043 15622746 12712474 17107899
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 9.5517217047 17712046 16766008 16891316 16140955 19225113 16331271 17301526 17368321 16788101 15748426 19075265 9834237 16935935 19035177 19642359 12679006 17649720 19029980 17506722 17294898 16823087 17361223 17107899 17339181
MESH:D015458 Leukemia, T-Cell arsenic trioxide 9.2516882451
MESH:D015458 Leukemia, T-Cell Curcumin 9.2516106398
MESH:D007964 Leukocytosis Indomethacin 4.5816537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 4.9217980183
MESH:D007970 Leukopenia Lipopolysaccharides 3.9215821434
MESH:D007984 Leydig Cell Tumor vinclozolin 3.9516417039
MESH:D017880 Limb Deformities, Congenital Thalidomide 6.5810473037
MESH:D017880 Limb Deformities, Congenital Tretinoin 6.589224671
MESH:D008080 Liposarcoma Paclitaxel 4.1017353645
MESH:D008101 Liver Abscess, Amebic Indomethacin 4.9211479899
MESH:D008103 Liver Cirrhosis arsenite 15.5518296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 15.5521278145 17157831 17174718 16943688 17334410 11903743 16239168 11408273 16221502
MESH:D008103 Liver Cirrhosis Dietary Fats 15.5518296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 15.5519638242 20032147 18522880 18665156 18407596
MESH:D008103 Liver Cirrhosis Thalidomide 15.5516943688 17174718
MESH:D008105 Liver Cirrhosis, Biliary marker/mechanism 21399635
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.669327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental 1,3-dimethylthiourea 24.3811682029
MESH:D008106 Liver Cirrhosis, Experimental atorvastatin 24.3817347453
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 24.3816638106 12586293 18054572 17721639 15925388 15362042 14724832 17525996 18277467 18339082 14716833 18187930 20821823 18376398 18395095 17631135 18006644 17976157 18472094 16027843 17869086 17766677 14512876 17761835 17823541 18481824 15370692 18210741 17900296 18166357 11481614 12546737 12609069 15123356 18472332 15338365 12389079 15818738 14748882 17805973 16033810 12445421 14716496 18395914 15931870 18429990 12649538 10355542 17922224 18418968 18420326 18251166 12445418 15057751 17481882 18705752 16136751 15650968 14620537 15876570 12666154 15893842 17698563 17944888 16015684 15959796 16097048 18317297 18156304 15673190 18205269 12667390 17565644 12898905 17708605 12632512 17640975 16192424 12958196 15996030 16248980 16011737 12741479 18263696 18412020 15052691 18279442 17557913 17714472 12632514 16116963 15730626 13678700
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 24.3818006644 17355460 18705752
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 24.3816718785
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 24.3817465448 16042886 17724770 18371158 18364076 15138612 17719030 17196135 16627068 16270385 17348192 18237412 15081153 17640959 17201889 15298665 15798949 12925901 15383259 16544323 17666798 15086199 17203207 12918455 14726149 17881167 17036385 16570917 18637143 15161499 15942678 15733078 15864749 18210741 14709902 14659978 15369754 15339415 15577212 15723089 15744066 15842777 16603200 15366600 18672772 16169303 15591649 15479170 17432682 18629640 15793283 15504291 15571005 18239293 15067225 15763062 14643895 18095165 15492853 14568256 18567088 17534399 17198567 16009107 15099470
MESH:D008106 Liver Cirrhosis, Experimental Dimethyl Sulfoxide 24.3811682029
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 24.3816595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 24.3814716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 24.3818194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 24.3812878042
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 24.3812878042
MESH:D008106 Liver Cirrhosis, Experimental Thalidomide 24.3815465738
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 24.3818397230 16248980
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 17.9617184895
MESH:D008107 Liver Diseases Acetaminophen 17.9616611625 19460945 12969438 16610002 19014921 12587719 11587558 19784758
MESH:D008107 Liver Diseases Antimony Sodium Gluconate 17.967570843
MESH:D008107 Liver Diseases Arsenic 17.9611134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 17.9616246199 15720792 16964402 15830285 17285989
MESH:D008107 Liver Diseases Curcumin 17.9616956363
MESH:D008107 Liver Diseases DDT 17.9615729006
MESH:D008107 Liver Diseases Diethylnitrosamine 17.9617034775
MESH:D017093 Liver Failure Carbon Tetrachloride 3.4115123358
MESH:D017114 Liver Failure, Acute Acetaminophen 12.3016871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 12.3014706259 16899240
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 12.3017457977
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 33.257678174
MESH:D008113 Liver Neoplasms Arsenic 33.2516368122
MESH:D008113 Liver Neoplasms arsenic trioxide 33.2514682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 33.2520195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 33.2521295105 19389873
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 33.2519294768
MESH:D008113 Liver Neoplasms DDT 33.2515975961 11948501
MESH:D008113 Liver Neoplasms Diethylnitrosamine 33.2519073162 18977376 20137499 19254457 19690152 18648771 16942905 20501860 18754104 15885732 21278145 15175105 12771043 21071580 19812893 21167192 19427195 21047994 19426721 19642983 19499222 19090486 20452335 2422723 18644402 2862719 19833225 18978307 12112319 20492335 19638242 10737359 20405173 19551842 19256749 19850985 20434301 20101389 20583210 9163691 19255062 20118626 19294768 19996281
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 33.2515890375 3113478
MESH:D008113 Liver Neoplasms sodium arsenite 33.2516712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 33.2516984957
MESH:D008113 Liver Neoplasms zerumbone 33.2520452335
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 40.396135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 40.396587162 598648 3712494 1399818
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 40.3920377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 40.3912562636
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 40.3918164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 40.3912014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 40.3919519916 18775883 17854601 19126423 3124819 18544905 18308698 18093689 9362446 18079962 19009564 2563599 21159647 17942915 17174075 19539802 18282651 18164116 18253720 16842330 16267830 19004024
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 40.3915603536 1848544 6150874
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 40.3917085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Hexachlorobenzene 40.391423854
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 40.3912151625
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 40.397955063
MESH:D008133 Long QT Syndrome arsenic trioxide 6.6315213294
MESH:D008133 Long QT Syndrome Quinidine 6.6311989578 15350150
MESH:D008171 Lung Diseases Mustard Gas 9.1218161513 18702808
MESH:D008171 Lung Diseases Ozone 9.1219066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 9.1219095001
MESH:D017563 Lung Diseases, Interstitial Benzene 4.0214698565
MESH:D055370 Lung Injury Lipopolysaccharides 6.7421114838
MESH:D055370 Lung Injury Ozone 6.7420417186
MESH:D008175 Lung Neoplasms Arsenic 37.6819168569 17306315 17976673
MESH:D008175 Lung Neoplasms arsenic trioxide 37.6811798837 19825857
MESH:D008175 Lung Neoplasms arsenite 37.6816809336
MESH:D008175 Lung Neoplasms Asbestos 37.6812111688
MESH:D008175 Lung Neoplasms Benzene 37.6812562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 37.6820464547 6695378 18520028 20135361 17053015 18569708 20869020 20064080 18816296
MESH:D008175 Lung Neoplasms bexarotene 37.6817849452
MESH:D008175 Lung Neoplasms Cisplatin 37.6817225452 6189445 11798837
MESH:D008175 Lung Neoplasms Curcumin 37.6819359593 18462866 16243823
MESH:D008175 Lung Neoplasms Dexamethasone 37.6815824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 37.6820512841 20970405 21163286 6695378
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 37.6816061637 11884234 19555203
MESH:D008175 Lung Neoplasms Doxorubicin 37.686189445 17418594
MESH:D008175 Lung Neoplasms Indomethacin 37.6811053908 11497255 16537180
MESH:D008175 Lung Neoplasms Mustard Gas 37.688781369 3148597
MESH:D008175 Lung Neoplasms Ozone 37.688597069 7614698
MESH:D008175 Lung Neoplasms sodium arsenite 37.6815276417 16712894 17077188 19931552 17306315
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 37.6819555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 37.6811807781
MESH:D008223 Lymphoma Benzene 13.1117584886 17119257
MESH:D008223 Lymphoma Curcumin 13.1118462866
MESH:D008223 Lymphoma Doxorubicin 13.1116098063
MESH:D008223 Lymphoma Etoposide 13.1112854902 12556972
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 6.8017654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 6.8014749477
MESH:D016399 Lymphoma, T-Cell Curcumin 9.0416173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 9.0415621674
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.3911161223
MESH:D008231 Lymphopenia Antimony Sodium Gluconate 5.629770149
MESH:D008275 Magnesium Deficiency Magnesium 5.6717823441
MESH:D015674 Mammary Neoplasms, Animal Benzene 3.6812562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 16.5411921183
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 16.5415591091 19196722 19196723
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 16.5415458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 16.5411408345 11807958 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 16.548985016
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 16.5417312309
MESH:D020149 Manganese Poisoning Estradiol 3.6919453300
MESH:D008527 Medulloblastoma Tretinoin 2.4117453147
MESH:D008545 Melanoma Cisplatin 12.0912883367 18505091 12374674 16809738 11135225 17761969 16248763 17023156 18332650 18176117 12393984 15577323 16432458
MESH:D008545 Melanoma Curcumin 12.0918462866 17885582
MESH:D008545 Melanoma Doxorubicin 12.0916827129
MESH:D008545 Melanoma Paclitaxel 12.0916342250 12025231 12040289
MESH:D008545 Melanoma sodium arsenite 12.0919082730 16487513
MESH:D008545 Melanoma Thalidomide 12.0912829675 16098027 17089043
MESH:D008545 Melanoma Tretinoin 12.0916752155
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.0015990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.8119513568
MESH:D008569 Memory Disorders Curcumin 3.4217263510
MESH:D008591 Meningomyelocele Tretinoin 3.6616940565
MESH:D008654 Mesothelioma Asbestos 11.4416919927 16564556 18310086 16319530 18709470
MESH:D008654 Mesothelioma Cisplatin 11.4417638057
MESH:D008654 Mesothelioma Doxorubicin 11.4417638057
MESH:D008654 Mesothelioma zoledronic acid 11.4416675582
MESH:D008679 Metaplasia Ozone 4.3110496685
MESH:D008881 Migraine Disorders Indomethacin 6.3411903285
MESH:D008881 Migraine Disorders Magnesium 6.3418803445
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.7915792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 6.5916381670
MESH:D009062 Mouth Neoplasms Indomethacin 6.5912636206
MESH:D052016 Mucositis Doxorubicin 4.0117415656
MESH:D009101 Multiple Myeloma arsenic trioxide 29.6419549372 14977855 11468182 15949261 19417148
MESH:D009101 Multiple Myeloma Benzene 29.6417119195
MESH:D009101 Multiple Myeloma Curcumin 29.6419372569
MESH:D009101 Multiple Myeloma Dexamethasone 29.6415867202 16118317 15744524
MESH:D009101 Multiple Myeloma lenalidomide 29.6419112817 16118317 16433596
MESH:D009101 Multiple Myeloma Paclitaxel 29.6414749477
MESH:D009101 Multiple Myeloma Thalidomide 29.6417168659 15867202 15744524 19112817 15920492 19372569 15741222 15939924 16445831 19112201
MESH:D009101 Multiple Myeloma zoledronic acid 29.6419621390 18089719 16996129
MESH:D009102 Multiple Organ Failure Zymosan 4.4912130978 12879239 10479408 15259001 18160304 10890648 15213630 15834315 15241586 17724436
MESH:D009103 Multiple Sclerosis marker/mechanism 19525953
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.1417962980
MESH:D009135 Muscular Diseases atorvastatin 4.7116239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.8818349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 17.7716882451 16105982
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 17.779809623
MESH:D009190 Myelodysplastic Syndromes lenalidomide 17.7717076650
MESH:D009190 Myelodysplastic Syndromes Thalidomide 17.7718720364
MESH:D009190 Myelodysplastic Syndromes Tretinoin 17.7717596541
MESH:D009203 Myocardial Infarction Cocaine 5.0618072171
MESH:D009203 Myocardial Infarction Doxorubicin 5.0619429709 15857846
MESH:D017202 Myocardial Ischemia Arsenic 6.8815371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 6.8812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 2.6616810080
MESH:D009336 Necrosis 2,4-dinitrotoluene 7.7818551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 7.787678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 7.8716624393
MESH:D009361 Neoplasm Invasiveness Curcumin 7.8718495463
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 17.413581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 17.419029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 17.4118259882
MESH:D009362 Neoplasm Metastasis Indomethacin 17.4111239499 11053908 16537180
MESH:D009362 Neoplasm Metastasis Paclitaxel 17.4115867366
MESH:D009362 Neoplasm Metastasis zoledronic acid 17.4115867366 17312309 19139120
MESH:D009369 Neoplasms Benzo(a)pyrene 17.0811141357
MESH:D009369 Neoplasms Cisplatin 17.0816773208
MESH:D009369 Neoplasms DDT 17.088820588
MESH:D009369 Neoplasms Nicotine 17.0816365874
MESH:D009369 Neoplasms sodium arsenite 17.0811559025
MESH:D009369 Neoplasms Tretinoin 17.0816594593 16946489
MESH:D009369 Neoplasms Trichloroethylene 17.0811911487
MESH:D009374 Neoplasms, Experimental Indomethacin 6.7810663608 15625704
MESH:D009374 Neoplasms, Experimental sodium arsenite 6.7820056578
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 8.5119196722
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 8.5112497104
MESH:D009389 Neovascularization, Pathologic arsenite 12.6615738583
MESH:D009389 Neovascularization, Pathologic Estradiol 12.6617289903
MESH:D009389 Neovascularization, Pathologic Nicotine 12.6616365874
MESH:D009395 Nephritis, Interstitial Cisplatin 8.2315464296
MESH:D009395 Nephritis, Interstitial Tetracycline 8.239884423
MESH:D009397 Nephrocalcinosis Furosemide 5.0815086907
MESH:D009401 Nephrosis Doxorubicin 4.0116636307 16899518
MESH:D009404 Nephrotic Syndrome atorvastatin 7.7619348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 7.7616889571 15640375
MESH:D009421 Nervous System Malformations Estradiol 17.4511399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 17.4514600291
MESH:D009421 Nervous System Malformations Thalidomide 17.4516859833
MESH:D009421 Nervous System Malformations Tretinoin 17.459125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.8418462866
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 21.246679447
MESH:D009436 Neural Tube Defects Arsenic 21.2416620997
MESH:D009436 Neural Tube Defects arsenic trioxide 21.2410525206
MESH:D009436 Neural Tube Defects Benzene 21.2415643154
MESH:D009436 Neural Tube Defects sodium arsenite 21.2412854658
MESH:D009436 Neural Tube Defects Tretinoin 21.249142499
MESH:D009447 Neuroblastoma Cisplatin 5.588761367
MESH:D009447 Neuroblastoma Doxorubicin 5.5815555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 10.3118514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 10.3120387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 10.3112349958
MESH:D017599 Neuroectodermal Tumors Cisplatin 3.928761367
MESH:D020078 Neurogenic Inflammation Arsenic 3.6517056641
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.3220387270
MESH:D009503 Neutropenia Mustard Gas 3.2616761898 7688884
MESH:D052556 Niemann-Pick Disease, Type C Cholesterol 4.949802331 20557099
MESH:D053206 Nocturnal Enuresis Furosemide 5.0817945291
MESH:D009765 Obesity Curcumin 3.8819297423
MESH:D009765 Obesity Dietary Fats 3.8818674790 16723640 21332399 17217161 20518802 19632207 20132043 11836018 18457598
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.386374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 15.9916049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 15.9916049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 15.994026338 6482804
MESH:D009784 Occupational Diseases Benzene 15.9916737584 15576619 15935809 15612468 15913788 17178637 15727169 17119257 17479406
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.233988306
MESH:D010003 Osteoarthritis Indomethacin 3.157009135
MESH:D010014 Osteolysis Paclitaxel 9.7115867366
MESH:D010014 Osteolysis zoledronic acid 9.7115867366
MESH:D010024 Osteoporosis Curcumin 5.8818719352
MESH:D010024 Osteoporosis zoledronic acid 5.8817882678
MESH:D012516 Osteosarcoma Doxorubicin 3.4715930896
MESH:D010051 Ovarian Neoplasms Arsenic 32.4617306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 32.4616624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Benzene 32.4612562636
MESH:D010051 Ovarian Neoplasms Cisplatin 32.466897625 15464296 19769630 17225452
MESH:D010051 Ovarian Neoplasms Curcumin 32.4618462866 19020741
MESH:D010051 Ovarian Neoplasms Estradiol 32.4619401270
MESH:D010051 Ovarian Neoplasms Mifepristone 32.4616525653
MESH:D010051 Ovarian Neoplasms Paclitaxel 32.4611161223
MESH:D010051 Ovarian Neoplasms sodium arsenite 32.4617306315 15276417
MESH:D010051 Ovarian Neoplasms Thalidomide 32.4616288038
MESH:D010051 Ovarian Neoplasms Tretinoin 32.4616936753
MESH:D010146 Pain Acetaminophen 10.9016870215
MESH:D010146 Pain Indomethacin 10.9013679232 17627676 3291741 17440234
MESH:D010146 Pain Tretinoin 10.9016870215
MESH:D010146 Pain zoledronic acid 10.9016475674
MESH:D010149 Pain, Postoperative Indomethacin 3.8918702446 12538197
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 19.3115580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 19.3119003803
MESH:D010190 Pancreatic Neoplasms Curcumin 19.3117440100 19401701 19196508
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 19.3116540662
MESH:D010190 Pancreatic Neoplasms Etoposide 19.3119003803
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 19.3115976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 19.3115976015
MESH:D010195 Pancreatitis Antimony Sodium Gluconate 6.827519887
MESH:D010195 Pancreatitis Indomethacin 6.8217883296 15028970
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 11.287296757
MESH:D010212 Papilloma Hydrogen Peroxide 11.2812065085
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 11.2818922899 12065085 18404319 8330346
MESH:D010235 Paraganglioma arsenic trioxide 3.4419927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 4.9216537180
MESH:D010291 Paresis Thalidomide 5.519200351
MESH:D020734 Parkinsonian Disorders Indomethacin 3.4412349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 4.9211903285
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 11.1620133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 11.1612520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 4.6411026799
MESH:D010437 Peptic Ulcer Indomethacin 4.3711148446
MESH:C536657 Periodic fever, familial, autosomal dominant marker/mechanism
MESH:D010518 Periodontitis Antimony Sodium Gluconate 9.981325634
MESH:D010518 Periodontitis Indomethacin 9.9817225004
MESH:D010523 Peripheral Nervous System Diseases Arsenic 7.6116093927
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 7.6115464296
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.2115371236 16905509 6392382
MESH:D010538 Peritonitis Isoflurane 12.7917414419
MESH:D010538 Peritonitis Ozone 12.7916369182
MESH:D010538 Peritonitis Zymosan 12.7917826846 19088179 18977430 15259001 14761945 15979727 19641140 17371808 18760300 11985352 18557954
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 10.376228378
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 10.3711550810
MESH:D003557 Phyllodes Tumor Doxorubicin 4.3617983394
MESH:D010997 Pleural Neoplasms Cisplatin 11.3117638057
MESH:D010997 Pleural Neoplasms Doxorubicin 11.3117638057
MESH:D011014 Pneumonia Lipopolysaccharides 8.5312224865 11605937
MESH:D011014 Pneumonia Ozone 8.5318007984 18381685 18929643
MESH:D011041 Poisoning Mustard Gas 3.0915727166
MESH:D011141 Polyuria Furosemide 4.8717945291
MESH:D017119 Porphyria Cutanea Tarda Hexachlorobenzene 8.649918132
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 8.6418163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 2.892563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 6.3121297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Thalidomide 6.3117031469
MESH:D047928 Premature Birth Indomethacin 4.3717000239
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 6.9311896295 11118676 11399792 11222880
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 6.9318042343 19015723 18220299
MESH:D017096 Prion Diseases Tetracycline 4.6410903871
MESH:D011469 Prostatic Diseases vinclozolin 4.1618220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.1820887781
MESH:D011471 Prostatic Neoplasms Arsenic 4.1616140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 4.1619131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 4.1617292933
MESH:D011471 Prostatic Neoplasms Curcumin 4.1615129424 10851300 18226269 11398177 18156803 18769126 12497104
MESH:D011471 Prostatic Neoplasms DDT 4.1612584743
MESH:D011471 Prostatic Neoplasms Doxorubicin 4.1618437689 16729912 15749863 16888761 16868541 15897917
MESH:D011471 Prostatic Neoplasms Estradiol 4.1616740699
MESH:D011471 Prostatic Neoplasms Etoposide 4.1617172428
MESH:D011471 Prostatic Neoplasms Paclitaxel 4.1616356831 17172428 17136230 16729912
MESH:D011471 Prostatic Neoplasms sodium arsenite 4.1616039940
MESH:D011471 Prostatic Neoplasms Thalidomide 4.1616729912
MESH:D011471 Prostatic Neoplasms zoledronic acid 4.1619103299 12438248
MESH:D011472 Prostatitis vinclozolin 4.1618629315
MESH:D011507 Proteinuria Arsenic 11.3621343184
MESH:D011507 Proteinuria Indomethacin 11.3611849393
MESH:D011507 Proteinuria Tretinoin 11.3616636307
MESH:D011536 Prurigo Thalidomide 5.5112755975
MESH:D011537 Pruritus Mustard Gas 7.7618058305
MESH:D011537 Pruritus Naloxone 7.7615861022
MESH:D011618 Psychotic Disorders Cocaine 4.2316134406
MESH:D011625 Pterygium Tretinoin 4.0116723453
MESH:D011656 Pulmonary Emphysema Curcumin 3.8419168576
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.5717620002 17894541 10334151 17720292 17266442
MESH:D012021 Reflex, Abnormal Pentobarbital 5.2410930210
MESH:D051437 Renal Insufficiency Cisplatin 7.8715464296
MESH:D051437 Renal Insufficiency Doxorubicin 7.8717922066
MESH:D015427 Reperfusion Injury Furosemide 3.4716526316
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 11.2110666014 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 11.2118379247 11700416
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 11.2116096441 15912074 12394941
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.1810835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.0918990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 2.773692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.3816283617 16116481
MESH:D012509 Sarcoma Curcumin 7.2918462866
MESH:D012509 Sarcoma Doxorubicin 7.2916767912 17203757 17710206 15625365 15675481 18313854
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 24.4716646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 24.4714601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 24.4716326096 14601052
MESH:D012512 Sarcoma, Ewing's Etoposide 24.4714601052
MESH:D012512 Sarcoma, Ewing's zoledronic acid 24.4716121404
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.0117846226
MESH:D019873 Schnitzler Syndrome Thalidomide 5.1616096327
MESH:D012640 Seizures 2,4-dinitrotoluene 12.6518551238
MESH:D012640 Seizures 2,6-dinitrotoluene 12.6518551238
MESH:D012640 Seizures Cocaine 12.6510454489
MESH:D012640 Seizures Nicotine 12.6517873105
MESH:D012640 Seizures Pentobarbital 12.6510087439 9754883
MESH:D018805 Sepsis Curcumin 12.0018389075
MESH:D018805 Sepsis Isoflurane 12.0017414419
MESH:D018805 Sepsis Zymosan 12.0011441115
MESH:D012871 Skin Diseases Arsenic 6.5515952646 16702368 16759981 16353154 17050553 17938729 19834688 17548696 17453740 6392382 18709164
MESH:D012871 Skin Diseases monomethylarsonic acid 6.5521378128
MESH:D012871 Skin Diseases Mustard Gas 6.5515451306 16961503 12880345
MESH:D012878 Skin Neoplasms Arsenic 28.3419538983 17029826 15504454 17050553 17976673 16251483
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 28.3419755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 28.3415692506
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 28.3412065085
MESH:D012878 Skin Neoplasms sodium arsenite 28.3419524636 18572023
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 28.348532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 28.3416192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 28.348985016 11807781 8330346 12065085 18404319
MESH:D012878 Skin Neoplasms Tretinoin 28.3416467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.5515464296
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.8117203757 15625365 16767912
MESH:D016135 Spinal Dysraphism sodium arsenite 3.1712854658
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.4812587719
MESH:D013163 Splenomegaly Antimony Sodium Gluconate 5.479665985
MESH:D013272 Stomach Diseases Dexamethasone 7.8115472012
MESH:D013272 Stomach Diseases Indomethacin 7.8116280098 10215738 16184426 15038085 17638125 18209964 18545984 10486359 16113693 10192188 17207306 17160473 15472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 16.6817007042
MESH:D013274 Stomach Neoplasms Benzene 16.6812562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 16.6820155912 2093021
MESH:D013274 Stomach Neoplasms Butylated Hydroxyanisole 16.681399818 3581430
MESH:D013274 Stomach Neoplasms Cisplatin 16.6817522103 15958060 18396642
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 16.6818456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 16.6816033868
MESH:D013274 Stomach Neoplasms Furosemide 16.6817052386
MESH:D013274 Stomach Neoplasms Indomethacin 16.6815609394
MESH:D013274 Stomach Neoplasms Paclitaxel 16.6818506536 18396642
MESH:D013274 Stomach Neoplasms Tretinoin 16.6817261132
MESH:D013276 Stomach Ulcer Curcumin 15.2819188055 16631530
MESH:D013276 Stomach Ulcer Dexamethasone 15.2815138204
MESH:D013276 Stomach Ulcer Indomethacin 15.2816755016 11523592 17895592 18193104 18087811 18726076 18543354 17654042 17135157 11906479 12467913 16934674 15138204 18237397 14567935 11595415 16397915 17657623 11729361 16631530 11145282 18181030 17627676 18209962 16150113 11595431 12498302 12500499 18431645 17977527 12077510 16252198 10750652 1323529 18299717 12787963 15104355 10423059 16169175 10878458 17918041 15255614
MESH:D013276 Stomach Ulcer pimagedine 15.2818209962
MESH:D013276 Stomach Ulcer Thalidomide 15.2815138204
MESH:D013375 Substance Withdrawal Syndrome Pentobarbital 4.299754883 11529278
MESH:D024801 Tauopathies Paclitaxel 4.0416930453
MESH:D013736 Testicular Neoplasms Cisplatin 3.9117225452 15464296
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 7.7620133375
MESH:D013921 Thrombocytopenia Lipopolysaccharides 7.7615821434
MESH:D013953 Thymus Neoplasms Benzene 4.1810850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.1112697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 20.093712494 7505956 1399818 6582329 6587162
MESH:D013964 Thyroid Neoplasms arsenic trioxide 20.0919014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 20.097505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 20.0916010429 17909728
MESH:D013964 Thyroid Neoplasms Indomethacin 20.0918791128 14736730 11352223
MESH:D013964 Thyroid Neoplasms Tretinoin 20.0916026305 17045167
MESH:D013978 Tibial Fractures Estradiol 3.8919048282
OMIM:188890 TOBACCO ADDICTION, SUSCEPTIBILITY TO Nicotine 4.1316785264 11259349 16720336
MESH:D014029 Tobacco Use Disorder Nicotine 4.6917979512 18305452 18041664 15735609
MESH:D014062 Tongue Neoplasms Tretinoin 3.1016051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.1915213294
MESH:D014376 Tuberculosis Tretinoin 2.6916040207
MESH:D014456 Ulcer Indomethacin 4.1217380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 41.1316049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 41.1316049721
MESH:D001749 Urinary Bladder Neoplasms 2-Naphthylamine 41.1311144890
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 41.138074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 41.1317976673 17306315 19322015 11144890 18640142 19429237 15987713
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 41.1312845720 11780464 20435036 12973940
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 41.1317053015
MESH:D001749 Urinary Bladder Neoplasms Butylated Hydroxyanisole 41.131399818
MESH:D001749 Urinary Bladder Neoplasms Cacodylic Acid 41.1315537745
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 41.1312973940 15464296 17225452
MESH:D001749 Urinary Bladder Neoplasms Curcumin 41.1318593936
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 41.1317653716
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 41.1317306315 11723127 16452187 16712894
MESH:D014565 Urogenital Neoplasms Curcumin 4.4918462866
MESH:D014570 Urologic Diseases DDT 4.8516487989
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 9.4110091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 9.4110091137
MESH:D014581 Urticaria Acetaminophen 2.2710982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 11.9416803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 11.9411813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 11.9416129372
MESH:D014594 Uterine Neoplasms Benzene 3.6012562636
MESH:D014604 Uveal Neoplasms Tretinoin 3.8216752155
MESH:D014605 Uveitis Dexamethasone 9.671336536
MESH:D014605 Uveitis Zymosan 9.6711006244
MESH:D014625 Vaginal Neoplasms Cisplatin 3.8515577323
MESH:D014652 Vascular Diseases Arsenic 15.7817056641
MESH:D014652 Vascular Diseases sodium arsenite 15.7817056641
MESH:D014652 Vascular Diseases Thalidomide 15.7815741222
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.8012125929
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.4717638931 17678736 17334414 16364871
MESH:D014820 Vitiligo Tretinoin 3.3216761959
MESH:D014839 Vomiting Cisplatin 8.9111897121
MESH:D014839 Vomiting Indomethacin 8.9111897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.4615886252
MESH:D015430 Weight Gain Dietary Fats 3.0716723640
MESH:D009396 Wilms Tumor Tretinoin 3.2916287080
Pathway ID Pathway Name
KEGG:04920 Adipocytokine signaling pathway
KEGG:05010 Alzheimer's disease
KEGG:05014 Amyotrophic lateral sclerosis (ALS)
KEGG:04210 Apoptosis
REACT:578 Apoptosis
KEGG:05142 Chagas disease (American trypanosomiasis)
KEGG:04060 Cytokine-cytokine receptor interaction
KEGG:05160 Hepatitis C
KEGG:04010 MAPK signaling pathway
KEGG:04380 Osteoclast differentiation
KEGG:05145 Toxoplasmosis
KEGG:05152 Tuberculosis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36609
    • No data
    Releated disease ID Related disease Name
    PA445019Myocardial Infarction
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA449515etanercept
    PA452639infliximab
    PA10004adalimumab
    PA165107055certolizumab pegol
    PA133950441hmg coa reductase inhibitors
    PA449780glutathione
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB03507 - 6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved