Annotation Detail for TNP2
Basic Information
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| Gene Symbol: | TNP2 ( MGC116783,MGC116785,TP2 ) |
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| Gene Full Name: | transition protein 2 (during histone to protamine replacement) |
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| Band: | 16p13.13 |
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| Quick Links | Entrez ID:7142; OMIM: 190232; Uniprot ID:STP2_HUMAN; ENSEMBL ID: ENSG00000178279; HGNC ID: 11952 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Desease Name |
|---|
| type 1 diabetes |
| IMMUNE |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of TNP2 mRNA | affects expression | 16483693
|
| D004997 |
Ethinyl Estradiol |
Ethinyl Estradiol results in increased expression of TNP2 mRNA | increases expression | 15212814
|
| D017239 |
Paclitaxel |
Paclitaxel analog results in increased expression of TNP2 mRNA | increases expression | 15585946
|
| D017239 |
Paclitaxel |
Paclitaxel results in increased expression of TNP2 mRNA | increases expression | 15585946
|
| C006253 |
pirinixic acid |
pirinixic acid results in increased expression of TNP2 mRNA | increases expression | 12832660
|
| D018038 |
Sodium Selenite |
Sodium Selenite results in decreased expression of TNP2 mRNA | decreases expression | 18175754
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
4.10 | 18287403 |
| MESH:D000152 |
Acne Vulgaris |
|
Ethinyl Estradiol |
4.55 | 17505938 |
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.52 | 18653653 |
| MESH:D000230 |
Adenocarcinoma |
|
Ethinyl Estradiol |
1.88 | 14692618 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.02 | 16434500 |
| MESH:D001161 |
Arteriosclerosis |
|
Ethinyl Estradiol |
3.95 | 11256880 |
| MESH:D001169 |
Arthritis, Experimental |
|
Ethinyl Estradiol |
2.86 | 15885639 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.52 | 19483382 |
| MESH:D001859 |
Bone Neoplasms |
|
Paclitaxel |
4.97 | 15867366 |
| MESH:D001943 |
Breast Neoplasms |
|
Paclitaxel |
2.88 | 16115903 16273361 18234424 15136595 18323546 16244791 18223236 11325840 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Paclitaxel |
2.56 | 16313753 |
| MESH:D002779 |
Cholestasis |
|
Ethinyl Estradiol |
8.62 | 16105132 17333356 11677210 17110522 16919318 15861022 17681005 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
8.62 | 19176532 |
| MESH:D019457 |
Chromosome Breakage |
|
Sodium Selenite |
5.24 | 15894690 |
| MESH:D015179 |
Colorectal Neoplasms |
|
Paclitaxel |
2.45 | 18802399 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.56 | 18249437 |
| MESH:D003920 |
Diabetes Mellitus |
|
Sodium Selenite |
4.10 | 16285004 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Sodium Selenite |
2.36 | 15131321 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.85 | 12083418 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Ethinyl Estradiol |
3.63 | 12538720 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Paclitaxel |
2.96 | 16481741 |
| MESH:D005234 |
Fatty Liver |
|
Ethinyl Estradiol |
8.81 | 15345470 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
8.81 | 19236843 20131406 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.73 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.48 | 18467677 19772884 16221962 19176532 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.53 | 20558911 |
| MESH:D007021 |
Hypospadias |
|
Ethinyl Estradiol |
4.29 | 16569931 16945680 |
| MESH:D007247 |
Infertility, Female |
|
Ethinyl Estradiol |
3.87 | 12013081 |
| MESH:D007248 |
Infertility, Male |
|
Ethinyl Estradiol |
2.71 | 17937319 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
8.04 | 16306350 |
| MESH:D007333 |
Insulin Resistance |
|
Sodium Selenite |
8.04 | 14714311 |
| MESH:D008080 |
Liposarcoma |
|
Paclitaxel |
5.23 | 17353645 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.92 | 15890375 16377806 20007298 |
| MESH:D016393 |
Lymphoma, B-Cell |
|
Sodium Selenite |
4.46 | 14737004 |
| MESH:D008228 |
Lymphoma, Non-Hodgkin |
|
Paclitaxel |
4.40 | 14749477 |
| MESH:D008545 |
Melanoma |
|
Paclitaxel |
2.62 | 16342250 12025231 12040289 |
| MESH:D009101 |
Multiple Myeloma |
|
Paclitaxel |
3.93 | 14749477 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.99 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.26 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.22 | 16411023 |
| MESH:D009362 |
Neoplasm Metastasis |
|
Paclitaxel |
3.37 | 15867366 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.09 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.88 | 20558911 |
| MESH:D010014 |
Osteolysis |
|
Paclitaxel |
5.52 | 15867366 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Paclitaxel |
3.07 | 11161223 |
| MESH:D016584 |
Panic Disorder |
|
Ethinyl Estradiol |
4.09 | 11578682 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Paclitaxel |
3.47 | 16356831 17172428 16729912 17136230 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Sodium Selenite |
3.47 | 18760546 |
| MESH:D011537 |
Pruritus |
|
Ethinyl Estradiol |
3.85 | 16919318 15861022 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.53 | 19058328 |
| MESH:D013088 |
Spermatocele |
|
Ethinyl Estradiol |
4.55 | 16709447 |
| MESH:D013274 |
Stomach Neoplasms |
|
Paclitaxel |
2.45 | 18396642 18506536 |
| MESH:D024801 |
Tauopathies |
|
Paclitaxel |
5.35 | 16930453 |
| MESH:D019851 |
Thrombophilia |
|
Ethinyl Estradiol |
4.02 | 11994571 |
| MESH:D013927 |
Thrombosis |
|
Ethinyl Estradiol |
3.48 | 15669648 |
| MESH:D014594 |
Uterine Neoplasms |
|
Ethinyl Estradiol |
3.74 | 14692618 |
| MESH:D020246 |
Venous Thrombosis |
|
Ethinyl Estradiol |
3.91 | 14671159 15869587 |
PharmGKB Accession:PA36641
| Releated disease ID |
Related disease Name |
| PA443886 | Diabetes Mellitus |
| PA443888 | Diabetes Mellitus, Type 1 |
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