Annotation Detail for TNXB
Basic Information Top
| Gene Symbol: | TNXB ( HXBL,TENX,TN-X,TNX,TNXB1,TNXB2,TNXBS,XB,XBS ) |
|---|---|
| Gene Full Name: | tenascin XB |
| Band: | 6p21.33-p21.32 |
| Quick Links | Entrez ID:7148; OMIM: 600985; Uniprot ID:TENX_HUMAN; ENSEMBL ID: ENSG00000168477; HGNC ID: 11976 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| No data |
| Desease Name |
|---|
| Ehlers-Danlos Syndrome |
| HIV-1 control |
| INFECTION |
| Desease Name |
|---|
| HIV-1 control |
| Desease Name |
|---|
| Ehlers-Danlos syndrome, hypermobility type |
| Ehlers-Danlos due to tenascin X deficiency |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of TNXB mRNA | affects expression | 16483693 |
| D000968 | Antimycin A | Antimycin A results in decreased expression of TNXB mRNA | decreases expression | 19304788 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride affects the expression of TNXB mRNA | affects expression | 17484886 |
| D009151 | Mustard Gas | Mustard Gas results in decreased expression of TNXB mRNA | decreases expression | 18988085 |
| C084656 | paricalcitol | [Phosphorus co-treated with paricalcitol] results in increased expression of TNXB mRNA | affects cotreatment|increases expression | 17715259 |
| D010758 | Phosphorus | [Phosphorus co-treated with paricalcitol] results in increased expression of TNXB mRNA | affects cotreatment|increases expression | 17715259 |
| D012402 | Rotenone | Rotenone results in decreased expression of TNXB mRNA | decreases expression | 19304788 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000138 | Acidosis | Ammonium Chloride | 3.95 | 18287403 | |
| MESH:D001249 | Asthma | Mustard Gas | 2.78 | 10378619 | |
| MESH:D001768 | Blister | Mustard Gas | 5.56 | 19167455 | |
| MESH:D001989 | Bronchiolitis Obliterans | Mustard Gas | 5.56 | 15286001 | |
| MESH:D029481 | Bronchitis, Chronic | Mustard Gas | 5.42 | 17687719 10378619 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 4.14 | 16011737 16192424 16124888 16097048 15721981 10355542 16227642 15700767 16050911 3786805 18705752 15673190 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 1.85 | 18788625 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 2.10 | 6623471 10915739 3786805 21278145 19336974 2869522 9327722 16177239 11566570 10092053 3732212 17522070 7440962 19085960 15027814 15968718 7179309 6884620 15998439 7120509 4309450 16227642 | |
| MESH:D004487 | Edema | Mustard Gas | 3.59 | 9260866 11428647 11428631 11402378 | |
| MESH:C536193 | Ehlers-Danlos syndrome caused by tenascin-X deficiency | marker/mechanism | |||
| MESH:C536196 | Ehlers-Danlos syndrome type 3 | marker/mechanism | |||
| MESH:D004890 | Erythema | Mustard Gas | 5.56 | 9357497 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 3.45 | 12631006 15959796 19224547 16045604 61145 17595544 12795759 16239168 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 3.81 | 18705752 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 3.92 | 19900420 19110552 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 4.93 | 16899240 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 4.45 | 15338365 | |
| MESH:D007249 | Inflammation | Mustard Gas | 2.91 | 11402378 9260866 11428631 8975870 11428647 17524151 16001271 9357497 11428620 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 2.94 | 21278145 17157831 11408273 16943688 16239168 16221502 17334410 17174718 11903743 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 1.75 | 18705752 14716496 18317297 14748882 15650968 17805973 17922224 12632512 17944888 17525996 15959796 17640975 12389079 12632514 16011737 12898905 18481824 15876570 12445418 12741479 14716833 17481882 16116963 12445421 16097048 18429990 12609069 15362042 15370692 12586293 15057751 15123356 14620537 15996030 16638106 18472332 11481614 17869086 16033810 15673190 15893842 17557913 14512876 18156304 18006644 18279442 15931870 17631135 14724832 13678700 20821823 15818738 15052691 10355542 18166357 12667390 18205269 17708605 15925388 12958196 18263696 18472094 17900296 18277467 18420326 12649538 18395095 18395914 17976157 18418968 17565644 16015684 18054572 15730626 17698563 17714472 18210741 18187930 17721639 18376398 16248980 12666154 17766677 17823541 18251166 17761835 16192424 16136751 16027843 12546737 18339082 18412020 15338365 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 2.13 | 16964402 15720792 16246199 15830285 17285989 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 4.52 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 3.95 | 14706259 16899240 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 2.30 | 19294768 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 2.77 | 12014681 15583823 | |
| MESH:D008171 | Lung Diseases | Mustard Gas | 3.62 | 18702808 18161513 | |
| MESH:D008175 | Lung Neoplasms | Mustard Gas | 2.17 | 3148597 8781369 | |
| MESH:D009410 | Nerve Degeneration | Rotenone | 4.09 | 18619942 15790535 17356569 | |
| MESH:D009503 | Neutropenia | Mustard Gas | 4.27 | 7688884 16761898 | |
| MESH:D010300 | Parkinson Disease | Rotenone | 3.06 | 11445065 19114014 16412576 16140633 18619942 15451049 19232380 18191903 11535288 | |
| MESH:D020734 | Parkinsonian Disorders | Rotenone | 4.34 | 15927086 18197244 15795934 15574749 | |
| MESH:D011041 | Poisoning | Mustard Gas | 4.10 | 15727166 | |
| MESH:D011537 | Pruritus | Mustard Gas | 4.49 | 18058305 | |
| MESH:D011658 | Pulmonary Fibrosis | Mustard Gas | 3.01 | 17266442 17894541 10334151 17720292 17620002 | |
| MESH:D012871 | Skin Diseases | Mustard Gas | 2.77 | 12880345 15451306 16961503 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:04512 | ECM-receptor interaction |
| KEGG:04510 | Focal adhesion |
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