AutismKB 2.0

Annotation Detail for TPI1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TPI1 ( MGC88108,TPI )
Gene Full Name: triosephosphate isomerase 1
Band: 12p13.31
Quick LinksEntrez ID:7167; OMIM: 190450; Uniprot ID:TPIS_HUMAN; ENSEMBL ID: ENSG00000111669; HGNC ID: 12009
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
GLYCOLYSISglycolysis I
PWY66-373sucrose degradation
PWY-5484glycolysis II
ANAGLYCOLYSIS-PWYglycolysis III
Pathway IDPathway Name
hsa00562Inositol phosphate metabolism
hsa00010Glycolysis / Gluconeogenesis
hsa01100Metabolic pathways
hsa00051Fructose and mannose metabolism
Pathway IDPathway Name
Metabolism of carbohydrates
No data
No data
Pathway IDPathway Name
500678Gluconeogenesis
500676Glucose metabolism
500677Glycolysis
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1715Myotonic disorder
1770Melanoma
1800Lupus vulgaris
1877Multiple sclerosis
2025Polyarthritis
2146Lupus erythematosus
No data
No data
Desease Name
Hemolytic anemia due to triosephosphate isomerase deficiency
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of TPI1 mRNAaffects expression 21346803
C024709 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone binds to TPI1 proteinaffects binding 16533022
C028451 3,4,3',4'-tetrachlorobiphenyl 3,4,3',4'-tetrachlorobiphenyl results in decreased activity of TPI1 proteindecreases activity 15556062
D000082 Acetaminophen Acetaminophen affects the expression of TPI1 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased expression of TPI1 proteinincreases expression 15800402
D000643 Ammonium Chloride Ammonium Chloride affects the expression of TPI1 mRNAaffects expression 16483693
D001151 Arsenic Arsenic affects the expression of TPI1 mRNAaffects expression 18315880
D001151 Arsenic Arsenic results in decreased expression of TPI1 mRNAdecreases expression 18315880
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of TPI1 mRNAincreases expression 20127859
C110172 BHTOH-QM BHTOH-QM binds to TPI1 proteinaffects binding 16533022
C006780 bisphenol A bisphenol A results in increased expression of TPI1 mRNAincreases expression 12075121
C032036 bromobenzene bromobenzene metabolite binds to TPI1 proteinaffects binding 17305373
D002245 Carbon Dioxide Carbon Dioxide results in increased expression of TPI1 mRNAincreases expression 14762718
D003024 Clozapine Clozapine results in increased expression of TPI1 mRNAincreases expression 15860345
C018021 cobaltous chloride cobaltous chloride results in increased expression of TPI1 mRNAincreases expression 14762718
D016572 Cyclosporine Cyclosporine results in decreased expression of TPI1 mRNAdecreases expression 20106945
D003676 Deferoxamine Deferoxamine results in increased expression of TPI1 mRNAincreases expression 14762718
D002945 Cisplatin TPI1 protein affects the susceptibility to Cisplatinaffects response to substance 18309519
D004099 Dihydroxyacetone Phosphate TPI1 protein affects the metabolism of Dihydroxyacetone Phosphateaffects metabolic processing 14762718
D004317 Doxorubicin TPI1 protein affects the susceptibility to Doxorubicinaffects response to substance 18309519
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of TPI1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of TPI1 mRNAincreases expression 15576828
12075121
D005472 Fluorouracil Fluorouracil results in decreased expression of TPI1 mRNAdecreases expression 16510598
D005472 Fluorouracil TPI1 protein affects the susceptibility to Fluorouracilaffects response to substance 18309519
D019833 Genistein Genistein results in increased expression of TPI1 mRNAincreases expression 12075121
D006220 Haloperidol Haloperidol results in increased expression of TPI1 mRNAincreases expression 15860345
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of TPI1 mRNAaffects cotreatment|increases expression 17183730
D007052 Ibuprofen Ibuprofen affects the expression of TPI1 proteinaffects expression 18351690
D007052 Ibuprofen Ibuprofen results in increased expression of TPI1 mRNAincreases expression 18351690
D009151 Mustard Gas Mustard Gas affects the expression of TPI1 mRNAaffects expression 15651846
C022838 nickel chloride nickel chloride results in increased expression of TPI1 mRNAincreases expression 12839937
D010665 Phenylpropanolamine Phenylpropanolamine results in decreased expression of TPI1 mRNAdecreases expression 16465460
D010795 Phthalic Acids Phthalic Acids results in decreased expression of TPI1 mRNAdecreases expression 15728792
C006253 pirinixic acid pirinixic acid results in increased expression of TPI1 mRNAincreases expression 16940010
D011794 Quercetin Quercetin results in increased expression of TPI1 proteinincreases expression 17292933
D012643 Selenium Selenium results in increased expression of TPI1 mRNAincreases expression 19244175
C017947 sodium arsenite sodium arsenite results in increased expression of TPI1 proteinincreases expression 15899475
D013629 Tamoxifen Tamoxifen affects the expression of TPI1 mRNAaffects expression 17555576
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of TPI1 mRNAaffects cotreatment|increases expression 17183730
D014750 Vincristine TPI1 protein affects the susceptibility to Vincristineaffects response to substance 18309519
D014810 Vitamin E Vitamin E results in increased expression of TPI1 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1714745880
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 3.138875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.6019490988
MESH:D000138 Acidosis Ammonium Chloride 3.1918287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5717505938
MESH:D058186 Acute Kidney Injury Cisplatin 8.0212690470 15814532 17670903
MESH:D058186 Acute Kidney Injury Ibuprofen 8.026375363
MESH:D055371 Acute Lung Injury pirinixic acid 2.7818653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 22.9520464547 20127859
MESH:D000230 Adenocarcinoma Cisplatin 22.9517638652 11798837
MESH:D000230 Adenocarcinoma Doxorubicin 22.9517418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 22.9514692618
MESH:D000230 Adenocarcinoma Fluorouracil 22.9517638652
MESH:D000230 Adenocarcinoma Genistein 22.9511473722
MESH:D000230 Adenocarcinoma Ibuprofen 22.9510697514
MESH:D000230 Adenocarcinoma Vincristine 22.9519825857
MESH:D000236 Adenoma Benzo(a)pyrene 2.446695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.1116434500
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3215276417
MESH:D018246 Adrenocortical Adenoma Arsenic 12.5417306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 12.5416712894 17306315
MESH:D000380 Agranulocytosis Clozapine 4.7014617031 16160616 12649775
MESH:D000419 Albuminuria Doxorubicin 4.1921441931
MESH:D000544 Alzheimer Disease Ibuprofen 3.0918351690
MESH:D000550 Amblyopia Valproic Acid 4.8617688650
MESH:D000707 Anaphylaxis Ibuprofen 4.899532969
MESH:D000740 Anemia Fluorouracil 3.4017963324 15504547 16511603
MESH:D000743 Anemia, Hemolytic Quercetin 3.9117084956
MESH:D000746 Anemia, Hemolytic, Congenital Nonspherocytic marker/mechanism
MESH:D000799 Angioedema Acetaminophen 3.4710982225
MESH:D000855 Anorexia Phenylpropanolamine 5.4117684035
MESH:D001008 Anxiety Disorders Valproic Acid 3.2817497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7119183758
MESH:D020261 Arsenic Poisoning Arsenic 2.7616251483 12569548 16835338 18414634
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.4415885639
MESH:D001249 Asthma Mustard Gas 2.6010378619
MESH:D001260 Ataxia Telangiectasia Quercetin 4.6115336622
MESH:D050197 Atherosclerosis Arsenic 3.0312928151 19371607
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 4.1120106747
MESH:D001321 Autistic Disorder Acetaminophen 2.1318445737
MESH:D001321 Autistic Disorder Haloperidol 2.1319368416 18080171
MESH:D001321 Autistic Disorder Valproic Acid 2.1317688650 16609825 17157402 19232924 17507914 15238991 18316065 19460635 18985861 18775368 20603192 18558336 18396377 18177632 18940202
MESH:D001327 Autoimmune Diseases Quercetin 4.0519761891
MESH:D001714 Bipolar Disorder Valproic Acid 2.8920046352 17594078
MESH:D001768 Blister Mustard Gas 4.7919167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 2.8219483382
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.178888407
MESH:D019046 Bone Marrow Neoplasms Cisplatin 10.8114601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 10.8114601052
MESH:D001862 Bone Resorption bisphenol A 3.5411985600
MESH:D002545 Brain Ischemia Ibuprofen 4.5215837124
MESH:D001932 Brain Neoplasms Doxorubicin 3.4917150277
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 5.4220146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 5.4217123778
MESH:D001943 Breast Neoplasms Cisplatin 5.4219526202 18382427
MESH:D001943 Breast Neoplasms Deferoxamine 5.4215993339
MESH:D001943 Breast Neoplasms Doxorubicin 5.4217983394 15567936 15993339 17426702 16322301 16264153 16096432 15939500 18234424 16935488 16826403 18382427 11325840 15136595 15692762 18695136 19526202 15634643 15668708 16595493 15994142 17369602 18628466 16115903
MESH:D001943 Breast Neoplasms Fluorouracil 5.4219217205 18608205 15136595 18357371 16595493 16557594 16110121
MESH:D001943 Breast Neoplasms Genistein 5.4216873071 16541309 17200150
MESH:D001943 Breast Neoplasms Quercetin 5.4218628248
MESH:D001943 Breast Neoplasms Tamoxifen 5.4218425577 15668708 20135344 19221464 19059307 20544844 19289846 19200415 19103187 19487384 18997820 17261762 18821012 21138602 16273361 18815881 16818667 15565566 11161223 17893378 17242785 16873071 18984771 19084267 18351453 20390343 19066611 17440819 20005174 19155303 20065188 19189210 19244106 18629630 19410462 19189212 19115204 21152245 17049068 20859285 19142967 19011961 18855134 16202921 19288272
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.7915286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.6017687719 10378619
MESH:D002100 Cachexia Ibuprofen 5.1015141370
MESH:D002105 Cadmium Poisoning Quercetin 5.1716962696
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.5716050911
MESH:D002276 Carcinoid Tumor Doxorubicin 11.1016051944
MESH:D002276 Carcinoid Tumor Fluorouracil 11.1016051944
MESH:D002277 Carcinoma Fluorouracil 3.2817121937
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.3815504454 17687452
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1519066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 21.4816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 21.483084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 21.4816507464 17306315
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 21.4817982673
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 21.4816234567 17876044 16023760 18059187
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 21.4817971768 16799960 17088986 16332177 17045692 18930000
MESH:D006528 Carcinoma, Hepatocellular Genistein 21.4816924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 21.4819519916 12508355
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 21.4817306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 21.4816924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.6217123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.9012023789 16685392
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.6017234771
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 9.9716201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 9.9718695887
MESH:D002292 Carcinoma, Renal Cell Vincristine 9.9716201981
MESH:D002294 Carcinoma, Squamous Cell Arsenic 20.2015504454 18922899 17687452
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 20.2020419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 20.206189445 18337622 17066447
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 20.206189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 20.2018986760 17066447 16280240 16757204
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 20.2018572023
MESH:D002294 Carcinoma, Squamous Cell Vincristine 20.206189445
MESH:D002295 Carcinoma, Transitional Cell Arsenic 8.4518640142
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.4517572228
MESH:D006332 Cardiomegaly Quercetin 3.1119794523
MESH:D009202 Cardiomyopathies Doxorubicin 3.2917519947 17928571 17007740 17382496 16242529 16952015 16455267 17308081 16612575 17974986 15811867 16278810 15505089 16731534 16109756 16651473 16364871 17924179 15792986 16269455 17351982 17329180 15476868 17131338 18627295
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8116243910 17334414
MESH:D002318 Cardiovascular Diseases Arsenic 6.6617938729 19152805 15738583
MESH:D002318 Cardiovascular Diseases Genistein 6.6616332659
MESH:D002340 Carotid Artery Diseases Arsenic 4.0018022660 16973168
MESH:D002375 Catalepsy Haloperidol 4.541977408 15215559
MESH:D002386 Cataract Acetaminophen 2.3610977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 5.8112371664
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 5.8119524636 20056578
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.5720734317
MESH:D002779 Cholestasis Cyclosporine 11.7719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.7717333356 17681005 15861022 16919318 17110522 16105132 11677210
MESH:D002779 Cholestasis pirinixic acid 11.7719176532
MESH:D003072 Cognition Disorders Clozapine 4.6017123785
MESH:D003092 Colitis Selenium 3.4217936198
MESH:D003110 Colonic Neoplasms Fluorouracil 5.4317725105 17172411 18772588 15001691 17287894 16510598 16340194 17016597 17018589 17169374
MESH:D003110 Colonic Neoplasms Genistein 5.4317182828
MESH:D003110 Colonic Neoplasms Quercetin 5.4317191121 11134977 19056647 19440933 17148506 15741050 16640504
MESH:D015179 Colorectal Neoplasms Cisplatin 4.5015273666
MESH:D015179 Colorectal Neoplasms Doxorubicin 4.5018802399 18259882
MESH:D015179 Colorectal Neoplasms Fluorouracil 4.5018288408 17401013 18802399 16331619 17094418 16303861 17695437 18383874 16391804 15148649 17016601 18509181 16282729 17454858 18949393 15289873 14970324 16524972 18448328 17594712 20501625 17255274
MESH:D015179 Colorectal Neoplasms Quercetin 4.5018852136 18095365
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.598888407 17688650 16575769
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.5919769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.6618551238
MESH:D007644 Darier Disease Fluorouracil 4.4216733453
MESH:D016757 Death, Sudden, Cardiac Haloperidol 4.5020210726
MESH:D003704 Dementia Haloperidol 4.2511575062
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0019031437
MESH:D017449 Dermatitis, Allergic Contact cobaltous chloride 3.6915059100 11298694 16823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2518249437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.4419496084
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 4.4716402076
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.4716647724
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.1719279558
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.1815331141
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 13.6921346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 13.6916485898 11287661 19085960 11461765 10774834 18071297 15619225 11421492 16177239 11743745 19420014 10915739 17562736 12540782 19370779 17906064 12594235 11834606 12392966 16227642 16393943 10663392 19164858 18713872 2444490 19416960 16109766 19739265 19923254 17522070 12958197 12153990 16081117 11529661 16781746 14550746 14725611 11739529 14986274 12705907 15968718
MESH:D056486 Drug-Induced Liver Injury bromobenzene 13.6910092053 12628495
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 13.6917416283
MESH:D056486 Drug-Induced Liver Injury Selenium 13.6915131321
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 13.691733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7219426721
MESH:D004362 Drug Toxicity Cisplatin 7.6112231392 12649298 15033597 19839026
MESH:D004362 Drug Toxicity Doxorubicin 7.6118602426
MESH:D004374 Ductus Arteriosus, Patent Ibuprofen 5.2418446180 16133044 18450898
MESH:D050171 Dyslipidemias Clozapine 3.9216402076
MESH:D004421 Dystonia Valproic Acid 3.711851702
MESH:C538011 Eales disease Vitamin E 4.339068938
MESH:D004487 Edema Mustard Gas 5.8111402378 11428647 11428631 9260866
MESH:D004487 Edema pirinixic acid 5.8112083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 7.7912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 7.7919031437
MESH:D004714 Endometrial Hyperplasia Genistein 4.2216402032
MESH:D016889 Endometrial Neoplasms Doxorubicin 11.1217359293
MESH:D016889 Endometrial Neoplasms Genistein 11.1211473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 11.1216202921 17893378 19155303 20544844
MESH:D004715 Endometriosis Ibuprofen 4.2915652904
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.7818037988
MESH:D019446 Endotoxemia Ibuprofen 4.6011545620
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.7917275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 3.543922381 16628512
MESH:D004827 Epilepsy Valproic Acid 2.7420417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.287562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 3.947750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.703659116
MESH:D004890 Erythema Mustard Gas 4.799357497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.7016530937
MESH:D004938 Esophageal Neoplasms Cisplatin 6.7015464296 16481741 17638652 15173087 16785472
MESH:D004938 Esophageal Neoplasms Fluorouracil 6.7016481741 17638652 15173087 16785472 16337965
MESH:D005234 Fatty Liver Cyclosporine 21.1619224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 21.1615345470
MESH:D005234 Fatty Liver pirinixic acid 21.1619236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 21.1614986274 19224547
MESH:D005234 Fatty Liver Valproic Acid 21.1619224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0116709447
MESH:D005315 Fetal Diseases Valproic Acid 4.5116575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.788888407 18558336
MESH:D005334 Fever Ibuprofen 4.2716997862
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1614745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 10.2119069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 10.2119069698
MESH:D005355 Fibrosis Cyclosporine 7.6412639820 12168785
MESH:D005355 Fibrosis Quercetin 7.6419474275
MESH:D005534 Foot Diseases Arsenic 5.186392382
MESH:D005756 Gastritis Acetaminophen 3.3016983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.3116452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.858708960
MESH:D005909 Glioblastoma Doxorubicin 10.5817150277
MESH:D005909 Glioblastoma Genistein 10.5816598420
MESH:D005909 Glioblastoma Quercetin 10.5819804834
MESH:D005910 Glioma Fluorouracil 5.6716145905
MESH:D005910 Glioma Quercetin 5.6717643826
MESH:D006258 Head and Neck Neoplasms Cisplatin 11.6115102660 15464296
MESH:D006258 Head and Neck Neoplasms Doxorubicin 11.6115692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 11.6118337622 15102660 15162350
MESH:D034381 Hearing Loss Cisplatin 3.9919898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.1215464296
MESH:D006330 Heart Defects, Congenital 3,4,3',4'-tetrachlorobiphenyl 10.2611294989
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.2620471113
MESH:D006330 Heart Defects, Congenital Vitamin E 10.2616080930
MESH:D006331 Heart Diseases Doxorubicin 3.2316879835 12587719 17875725 16707910 14766674 16244371 16495754 16330681 18006777 18674790 16244372 17888722 16144979
MESH:D006333 Heart Failure Doxorubicin 10.4817481944
MESH:D006333 Heart Failure pirinixic acid 10.4820558911
MESH:D006333 Heart Failure Selenium 10.4817162251
MESH:D006394 Hemangiosarcoma Doxorubicin 3.5715692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0515720958
MESH:D006529 Hepatomegaly pirinixic acid 2.6418467677 16221962 19772884 19176532
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.5716863852 16490937
MESH:D006689 Hodgkin Disease Cisplatin 15.0516200630 16170182
MESH:D006689 Hodgkin Disease Doxorubicin 15.0515147373 17606976 18501091
MESH:D006689 Hodgkin Disease sodium arsenite 15.0512676792
MESH:D006689 Hodgkin Disease Vincristine 15.0516135485 15147373 17606976 16794504
MESH:D019584 Hot Flashes Vitamin E 3.6014716179
MESH:D006849 Hydrocephalus Valproic Acid 4.5017688650
MESH:D006930 Hyperalgesia Acetaminophen 2.4216870215
MESH:D006943 Hyperglycemia pirinixic acid 8.1920558911
MESH:D006943 Hyperglycemia Quercetin 8.1911834736 18262572
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.1417050553
MESH:D006948 Hyperkinesis Clozapine 4.5416046005
MESH:D006973 Hypertension Arsenic 7.8411953799 9931084 16076760
MESH:D006973 Hypertension Cyclosporine 7.8410903974
MESH:D006973 Hypertension Quercetin 7.8418356687
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.2716612254
MESH:D006984 Hypertrophy Ibuprofen 4.6516672835
MESH:D006987 Hypesthesia Arsenic 5.1816093927
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4516569931 16945680
MESH:D007235 Infant, Premature, Diseases Ibuprofen 5.4616133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 5.8217937319
MESH:D007248 Infertility, Male sodium arsenite 5.8215346721 12646999
MESH:D007249 Inflammation Ibuprofen 7.393291741
MESH:D007249 Inflammation Mustard Gas 7.3911428620 17524151 9260866 11402378 11428631 11428647 9357497 8975870 16001271
MESH:D007249 Inflammation Tamoxifen 7.3919457130
MESH:D007251 Influenza, Human Quercetin 16.4516624496
MESH:D007251 Influenza, Human Selenium 16.4516624496
MESH:D007251 Influenza, Human Vitamin E 16.4516624496
MESH:D007333 Insulin Resistance bisphenol A 6.5116393666
MESH:D007333 Insulin Resistance pirinixic acid 6.5116306350
MESH:D007627 Keloid Quercetin 4.6017086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0715604871
MESH:D007642 Keratosis Arsenic 4.6216930632 12749816
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.7715464296
MESH:D007674 Kidney Diseases Acetaminophen 25.5415629191 12587719
MESH:D007674 Kidney Diseases Cisplatin 25.5412231392 18289764 19839026 12649298 15190930
MESH:D007674 Kidney Diseases Cyclosporine 25.5418776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 25.5415369732 16775033 15699352
MESH:D007674 Kidney Diseases Quercetin 25.5416962696
MESH:D007674 Kidney Diseases sodium arsenite 25.5420008137
MESH:D007674 Kidney Diseases Vitamin E 25.5412488133
MESH:D007676 Kidney Failure, Chronic Doxorubicin 8.8916707910
MESH:D007676 Kidney Failure, Chronic Selenium 8.8916518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 15.3216705839
MESH:D007680 Kidney Neoplasms Cyclosporine 15.3212371664
MESH:D007680 Kidney Neoplasms Fluorouracil 15.3216985049
MESH:D007680 Kidney Neoplasms Tamoxifen 15.3218625569
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.4211231351
MESH:D007938 Leukemia Genistein 5.9217468513 18980019
MESH:D007938 Leukemia Quercetin 5.9217468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.7816085563
MESH:D015470 Leukemia, Myeloid, Acute Deferoxamine 4.1620368581
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 4.1617596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.3117339181
MESH:D008064 Lipidoses Clozapine 7.2117567588
MESH:D008064 Lipidoses Tamoxifen 7.2117567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 8.0516439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Genistein 8.0517823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 8.0515474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 8.0512741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 8.0518564211
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 8.0516169303
MESH:D008107 Liver Diseases Acetaminophen 3.7219460945 16611625 19784758 19014921 12969438 16610002 12587719 11587558
MESH:D008107 Liver Diseases Arsenic 3.7211134558
MESH:D017114 Liver Failure, Acute Acetaminophen 2.9216871587 17185352
MESH:D008113 Liver Neoplasms Arsenic 19.6116368122
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 19.6121137059 20195826
MESH:D008113 Liver Neoplasms Fluorouracil 19.6115113037 16603448 18383874 17045692
MESH:D008113 Liver Neoplasms pirinixic acid 19.6120007298 15890375 16377806
MESH:D008113 Liver Neoplasms Quercetin 19.6118980244
MESH:D008113 Liver Neoplasms sodium arsenite 19.6116712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 19.6116684651
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 5.4916842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Quercetin 5.4919519916
MESH:D008171 Lung Diseases Mustard Gas 10.9418161513 18702808
MESH:D008171 Lung Diseases sodium arsenite 10.9419095001
MESH:D008171 Lung Diseases Vitamin E 10.9416863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.8917228818
MESH:D008175 Lung Neoplasms Arsenic 19.3119168569 17306315 17976673
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 19.3117053015 20135361 18520028 18816296 20464547 18569708 20869020 6695378 20064080
MESH:D008175 Lung Neoplasms Cisplatin 19.3117225452 11798837 6189445
MESH:D008175 Lung Neoplasms Doxorubicin 19.316189445 17418594
MESH:D008175 Lung Neoplasms Fluorouracil 19.3115246190
MESH:D008175 Lung Neoplasms Mustard Gas 19.313148597 8781369
MESH:D008175 Lung Neoplasms Quercetin 19.3116280456
MESH:D008175 Lung Neoplasms sodium arsenite 19.3117077188 19931552 15276417 16712894 17306315
MESH:D008175 Lung Neoplasms Tamoxifen 19.3118625569
MESH:D008175 Lung Neoplasms Vincristine 19.316189445 19825857
MESH:D008175 Lung Neoplasms Vitamin E 19.3111062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.4215086387
MESH:D008223 Lymphoma Doxorubicin 3.2016098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.4917654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.2115621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3919428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 16.3115458769
MESH:D008325 Mammary Neoplasms, Experimental Genistein 16.3114578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Ibuprofen 16.3110697514
MESH:D008325 Mammary Neoplasms, Experimental Selenium 16.3115318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 16.3119196723 14580682 19196722 11731420 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.1719453300
MESH:D008545 Melanoma Cisplatin 6.7118332650 12393984 11135225 17023156 12374674 18176117 12883367 16809738 16248763 16432458 17761969 15577323 18505091
MESH:D008545 Melanoma Doxorubicin 6.7116827129
MESH:D008545 Melanoma sodium arsenite 6.7116487513 19082730
MESH:D008545 Melanoma Tamoxifen 6.7119393235 12393984
MESH:D018328 Melanoma, Amelanotic Cisplatin 17.5215990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 17.5215990972
MESH:D018328 Melanoma, Amelanotic Vincristine 17.5215990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2119513568
MESH:D001523 Mental Disorders Clozapine 7.1516856516
MESH:D001523 Mental Disorders Haloperidol 7.1516856516
MESH:D008654 Mesothelioma Cisplatin 9.3717638057
MESH:D008654 Mesothelioma Doxorubicin 9.3717638057
MESH:D008654 Mesothelioma Selenium 9.3715107826
MESH:D024821 Metabolic Syndrome X Clozapine 4.1119142101
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4116801185
MESH:D008881 Migraine Disorders Valproic Acid 2.9318803445 18765137
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.1715792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.6016381670
MESH:D009062 Mouth Neoplasms Fluorouracil 7.6016757204 18986760
MESH:D052016 Mucositis Doxorubicin 4.4217415656
MESH:D009135 Muscular Diseases pirinixic acid 3.1516239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.708888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 2.9417596541
MESH:D009203 Myocardial Infarction Doxorubicin 16.2019429709 15857846
MESH:D009203 Myocardial Infarction Genistein 16.2017141266
MESH:D009203 Myocardial Infarction pirinixic acid 16.2019151258
MESH:D009203 Myocardial Infarction Quercetin 16.2019595682
MESH:D009203 Myocardial Infarction Vincristine 16.2017284715
MESH:D017202 Myocardial Ischemia Arsenic 3.6915371236
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.6217141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.6216411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 12.6219207477
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.4918551238
MESH:D009362 Neoplasm Metastasis Doxorubicin 5.3518259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.3519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3919410462
MESH:D009369 Neoplasms Benzo(a)pyrene 17.3411141357
MESH:D009369 Neoplasms Cisplatin 17.3416773208
MESH:D009369 Neoplasms Fluorouracil 17.3416928823 18600527 18239605
MESH:D009369 Neoplasms pirinixic acid 17.3417405874
MESH:D009369 Neoplasms Quercetin 17.3415185748
MESH:D009369 Neoplasms sodium arsenite 17.3411559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.3120056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.6319189210 19200415 19196722
MESH:D009395 Nephritis, Interstitial Cisplatin 9.6715464296
MESH:D009395 Nephritis, Interstitial Ibuprofen 9.676375363
MESH:D009401 Nephrosis Doxorubicin 4.4116636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.2718481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.2715640375 16889571
MESH:D009410 Nerve Degeneration Ibuprofen 4.1110961664
MESH:D009421 Nervous System Malformations bisphenol A 8.7216427766 11399458
MESH:D009421 Nervous System Malformations Genistein 8.7216427766
MESH:D009436 Neural Tube Defects Arsenic 10.8116620997
MESH:D009436 Neural Tube Defects sodium arsenite 10.8112854658
MESH:D009436 Neural Tube Defects Valproic Acid 10.8116359493 8888407
MESH:D009447 Neuroblastoma Cisplatin 6.498761367
MESH:D009447 Neuroblastoma Doxorubicin 6.4915555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.5818514411
MESH:D017599 Neuroectodermal Tumors Cisplatin 10.608761367
MESH:D017599 Neuroectodermal Tumors Vincristine 10.6012837982
MESH:D020078 Neurogenic Inflammation Arsenic 9.5617056641
MESH:D020078 Neurogenic Inflammation Quercetin 9.5617929310
MESH:D009468 Neuromuscular Diseases marker/mechanism
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.1916436463
MESH:D009503 Neutropenia Mustard Gas 3.637688884 16761898
MESH:D009765 Obesity Clozapine 4.3618515891 19142110
MESH:D009765 Obesity pirinixic acid 4.3620558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.1112819281 16049721
MESH:D010003 Osteoarthritis Ibuprofen 3.917009135
MESH:D010024 Osteoporosis Genistein 3.0319401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 9.0116169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 9.0119495926
MESH:D012516 Osteosarcoma Doxorubicin 3.8215930896
MESH:D010049 Ovarian Diseases bisphenol A 4.6211985600
MESH:D010051 Ovarian Neoplasms Arsenic 13.6517306315
MESH:D010051 Ovarian Neoplasms Cisplatin 13.6519769630 6897625 15464296 17225452
MESH:D010051 Ovarian Neoplasms Genistein 13.6519005980
MESH:D010051 Ovarian Neoplasms Quercetin 13.6519005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 13.6515276417 17306315
MESH:D010146 Pain Acetaminophen 5.9916870215
MESH:D010146 Pain Ibuprofen 5.993291741
MESH:D010149 Pain, Postoperative Ibuprofen 4.7716678543
MESH:D010190 Pancreatic Neoplasms Cisplatin 11.2619003803
MESH:D010190 Pancreatic Neoplasms Fluorouracil 11.2619003803 15113037 16929163 16500647
MESH:D010190 Pancreatic Neoplasms Ibuprofen 11.2612384795
MESH:D010190 Pancreatic Neoplasms Quercetin 11.2616965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3511578682
MESH:D010523 Peripheral Nervous System Diseases Arsenic 8.9016093927
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 8.9015464296
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.6215371236 6392382 16905509
MESH:D003557 Phyllodes Tumor Doxorubicin 4.7817983394
MESH:D010954 Plasmacytoma Selenium 4.5115087411
MESH:D010997 Pleural Neoplasms Cisplatin 12.6917638057
MESH:D010997 Pleural Neoplasms Doxorubicin 12.6917638057
MESH:D011041 Poisoning Mustard Gas 3.4615727166
MESH:D011230 Precancerous Conditions Cyclosporine 8.0812371664
MESH:D011230 Precancerous Conditions Quercetin 8.0819056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Vincristine 4.4121297632
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 8.5210548101
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 8.5220603192
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 3.8820887781
MESH:D011471 Prostatic Neoplasms Arsenic 4.0316140617
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 4.0317292933
MESH:D011471 Prostatic Neoplasms bisphenol A 4.0316740699
MESH:D011471 Prostatic Neoplasms Doxorubicin 4.0315749863 16888761 16868541 18437689 16729912 15897917
MESH:D011471 Prostatic Neoplasms Fluorouracil 4.0319082440 18626508
MESH:D011471 Prostatic Neoplasms Genistein 4.0316925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms Ibuprofen 4.0317409433
MESH:D011471 Prostatic Neoplasms Quercetin 4.0317292933 14715546
MESH:D011471 Prostatic Neoplasms sodium arsenite 4.0316039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 4.0315067354
MESH:D011471 Prostatic Neoplasms Vitamin E 4.0315084515
MESH:D011507 Proteinuria Arsenic 8.5321343184
MESH:D011507 Proteinuria Ibuprofen 8.536375363
MESH:D011537 Pruritus Ethinyl Estradiol 8.3016919318 15861022
MESH:D011537 Pruritus Mustard Gas 8.3018058305
MESH:D019310 Pseudolymphoma Valproic Acid 4.1711422049 12752131
MESH:D011565 Psoriasis Cyclosporine 2.1016882103
MESH:D011595 Psychomotor Agitation Haloperidol 4.6011575062
MESH:D011618 Psychotic Disorders Clozapine 8.2815331141
MESH:D011618 Psychotic Disorders Haloperidol 8.2811575062
MESH:D011629 Puberty, Precocious bisphenol A 4.4210548101
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.7810334151 17720292 17266442 17894541 17620002
MESH:D012004 Rectal Neoplasms Fluorouracil 3.7018286688 16160472 18722050 15538739
MESH:D051437 Renal Insufficiency Cisplatin 9.1815464296
MESH:D051437 Renal Insufficiency Doxorubicin 9.1817922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.2019058328
MESH:D012208 Rhabdomyosarcoma Valproic Acid 3.8419155313
MESH:D012509 Sarcoma Doxorubicin 3.6716767912 18313854 15625365 15675481 17203757 17710206
MESH:D012512 Sarcoma, Ewing's Cisplatin 9.2914601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 9.2914601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.4217846226
MESH:D012554 Schistosomiasis japonica Quercetin 5.1716862918
MESH:D012559 Schizophrenia Clozapine 5.3317667964 17726453 11151749 16141801 19369910 20452607 17123785 20521326 20521320 20168265 11763009 18855531 18806925 20107430 20580759
MESH:D012559 Schizophrenia Haloperidol 5.3320107430 1830565 19369910 18513383
MESH:D012559 Schizophrenia Valproic Acid 5.3319110320 15737665
MESH:D012640 Seizures 2,4-dinitrotoluene 5.1218551238
MESH:D012640 Seizures Valproic Acid 5.1216876388 1511512 14763951 11738929 15475178 11044598 3137016 17978042
MESH:D012871 Skin Diseases Arsenic 7.3816702368 15952646 6392382 17050553 18709164 17938729 16353154 17548696 17453740 19834688 16759981
MESH:D012871 Skin Diseases Mustard Gas 7.3815451306 12880345 16961503
MESH:D012871 Skin Diseases Vitamin E 7.3818709164
MESH:D012878 Skin Neoplasms Arsenic 12.1219538983 16251483 17976673 17050553 15504454 17029826
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 12.1210029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 12.1215692506
MESH:D012878 Skin Neoplasms sodium arsenite 12.1218572023 19524636
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.9715464296
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2117203757 16767912 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 10.3116709447
MESH:D013088 Spermatocele Tamoxifen 10.3116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.6719457130
MESH:D016135 Spinal Dysraphism sodium arsenite 8.6112854658
MESH:D016135 Spinal Dysraphism Valproic Acid 8.6119490988
MESH:D013226 Status Epilepticus Valproic Acid 4.1712833885
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.212093021 20155912
MESH:D013274 Stomach Neoplasms Cisplatin 3.2115958060 18396642 17522103
MESH:D013274 Stomach Neoplasms Fluorouracil 3.2117522103 19084572 16424979 17498489 18396642 16951190 18567086 17172411 19015929 15786421
MESH:D020521 Stroke Vitamin E 3.2316517955
MESH:D019966 Substance-Related Disorders bisphenol A 3.6216045194 16684133
MESH:D015173 Supratentorial Neoplasms Vincristine 5.5112837982
MESH:D017180 Tachycardia, Ventricular Haloperidol 4.3620210726
MESH:D013736 Testicular Neoplasms Cisplatin 4.2917225452 15464296
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8515669648
MESH:D013964 Thyroid Neoplasms Doxorubicin 3.1016010429 17909728
MESH:D014062 Tongue Neoplasms Fluorouracil 3.6716280240
MESH:D014178 Translocation, Genetic Valproic Acid 4.8617262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.153119515
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 25.8516049721
MESH:D001749 Urinary Bladder Neoplasms Arsenic 25.8517976673 19322015 18640142 11144890 19429237 17306315 15987713
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 25.8517053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 25.8512973940 17225452 15464296
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 25.8517653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 25.8516720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 25.8516452187 16712894 17306315 11723127
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 25.8517572228 8653321 16712894
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.288888407
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.9510091137
MESH:D014581 Urticaria Acetaminophen 2.6410982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 14.0916803524
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 14.0916803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 14.0911813266
MESH:D014591 Uterine Diseases bisphenol A 4.6314652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.9514692618
MESH:D014605 Uveitis Cyclosporine 3.611336536
MESH:D014625 Vaginal Neoplasms Cisplatin 4.2515577323
MESH:D014652 Vascular Diseases Arsenic 10.6217056641
MESH:D014652 Vascular Diseases sodium arsenite 10.6217056641
MESH:D020301 Vasospasm, Intracranial Ibuprofen 4.8219057314
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2115869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.8617678736 17638931 17334414 16364871
MESH:D014839 Vomiting Cisplatin 4.3411897121
MESH:D015430 Weight Gain Clozapine 4.1616141801 17502770 20107430 20521320 20564506 16402076
MESH:D015431 Weight Loss Clozapine 4.7117933447
MESH:D014985 Xerophthalmia Cyclosporine 4.0717120751
Pathway ID Pathway Name
KEGG:00051 Fructose and mannose metabolism
KEGG:00010 Glycolysis / Gluconeogenesis
KEGG:00562 Inositol phosphate metabolism
KEGG:01100 Metabolic pathways
REACT:474 Metabolism of carbohydrates
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36689
    • No data
    No data
    Releated drug ID Related drug Name
    PA448625biotin
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB01093 - Synotic Otic Solution Free Radical Scavengers;Analgesics, Non-Narcotic;Solvents;Cryoprotective Agents
    DB01695 - N-Hydroxy-4-Phosphono-Butanamide
    DB02726 - 2-Phosphoglycolic Acid
    DB03026 - Phosphoglycolohydroxamic Acid
    DB03132 - 3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid
    DB03135 - [2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid
    DB03314 - Fluorotryptophane
    DB03379 - 2-Carboxyethylphosphonic Acid
    DB03900 - 2-Methyl-2-Propanol
    DB04184 - Acetate Ion Indicators and Reagents
    DB04326 - 1,3-Dihydroxyacetonephosphate
    DB04447 - 1,4-Dithiothreitol
    DB04510 - 3-Phosphoglyceric Acid
    DB07387 - 3-(BUTYLSULPHONYL)-PROPANOIC ACID
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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