Annotation Detail for C3
Basic Information Top
| Gene Symbol: | C3 ( AHUS5,ARMD9,ASP,CPAMD1 ) |
|---|---|
| Gene Full Name: | complement component 3 |
| Band: | 19p13.3 |
| Quick Links | Entrez ID:718; OMIM: 120700; Uniprot ID:CO3_HUMAN; ENSEMBL ID: ENSG00000125730; HGNC ID: 1318 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| hsa04145 | Phagosome |
| hsa05142 | Chagas disease |
| hsa05140 | Leishmaniasis |
| hsa05322 | Systemic lupus erythematosus |
| hsa05150 | Staphylococcus aureus infection |
| hsa04610 | Complement and coagulation cascades |
| Pathway ID | Pathway Name |
|---|---|
| Signaling by GPCR | |
| Signaling in Immune system |
| No data |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| 500405 | Peptide ligand-binding receptors |
| 500474 | Alternative complement activation |
| 500476 | Activation of C3 and C5 |
| Desease ID | Desease Name |
|---|---|
| Immune system diseases | |
| Primary immunodeficiency | |
| H00102 | Classic complement pathway component defects |
| Desease ID | Desease Name |
|---|---|
| 1740 | Alzheimer's disease |
| 1840 | Macular degeneration |
| 1870 | Drug abuse |
| 1901 | Endometriosis |
| 1907 | Depression |
| 1954 | Stroke |
| 1992 | Aortic valve disease |
| 1997 | Dental plaque |
| 2029 | Tuberculosis |
| 2032 | Kidney disease |
| 2097 | Hyperlipidemia |
| 2134 | Amyotrophic lateral sclerosis |
| 2146 | Lupus erythematosus |
| 2241 | Infertility |
| Desease Name |
|---|
| cirrhosis |
| Asthma |
| IMMUNE |
| respiratory syncytial virus bronchiolitis |
| INFECTION |
| Desease Name |
|---|
| Age-related macular degeneration |
| Desease Name |
|---|
| Hemolytic uremic syndrome, atypical, susceptibility to, 5 |
| C3 deficiency |
| Macular degeneration, age-related, 9 |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects the expression of C3 mRNA | affects expression | 18281256 |
| C035476 | 2,2',4,4'-tetrahydroxybenzophenone | 2,2',4,4'-tetrahydroxybenzophenone results in increased expression of C3 mRNA | increases expression | 15458795 |
| C404910 | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of C3 protein | increases expression | 11390168 |
| C009505 | 4,4'-diaminodiphenylmethane | 4,4'-diaminodiphenylmethane results in increased expression of C3 mRNA | increases expression | 18648102 |
| C016601 | 4-hydroxytamoxifen | 4-hydroxytamoxifen results in increased expression of C3 protein | increases expression | 11390168 |
| C041594 | 4-nonylphenol | 4-nonylphenol affects the expression of C3 mRNA | affects expression | 15792627 |
| C105260 | 4-tert-octylphenol | 4-tert-octylphenol results in increased expression of C3 mRNA | increases expression | 10822019 17011747 11086226 |
| C105260 | 4-tert-octylphenol | 4-tert-octylphenol results in increased expression of C3 protein | increases expression | 11086226 |
| C475050 | 7alpha-methyl-17alpha-ethynylestradiol | 7alpha-methyl-17alpha-ethynylestradiol results in increased expression of C3 mRNA | increases expression | 12117614 |
| C119737 | 8-prenylnaringenin | 8-prenylnaringenin results in increased expression of C3 mRNA | increases expression | 16522720 |
| C450832 | A2E compound | A2E compound analog results in increased cleavage of C3 protein | increases cleavage | 17060630 |
| C450832 | A2E compound | A2E compound analog results in increased expression of C3 protein modified form | increases expression | 17060630 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of C3 protein | affects expression | 16687475 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of C3 mRNA | affects expression | 16483693 |
| D000728 | Androgens | Androgens results in increased expression of C3 mRNA | increases expression | 12974607 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of C3 mRNA | decreases expression | 20127859 |
| C095105 | bexarotene | bexarotene results in decreased expression of C3 mRNA | decreases expression | 16648578 |
| C006780 | bisphenol A | bisphenol A results in increased expression of C3 mRNA | increases expression | 11086226 15456929 10822019 |
| C006780 | bisphenol A | bisphenol A results in increased expression of C3 protein | increases expression | 11086226 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of C3 mRNA | increases expression | 17484886 |
| C074702 | chromium hexavalent ion | chromium hexavalent ion results in decreased expression of C3 mRNA | decreases expression | 15003702 |
| C023600 | chromium oxide | chromium oxide results in decreased expression of C3 mRNA | decreases expression | 15003702 |
| C016310 | cobra venom factor | CFB protein affects the reaction [cobra venom factor results in decreased expression of C3 protein] | affects reaction|decreases expression | 11724962 |
| C016310 | cobra venom factor | CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium] results in increased cleavage of and results in increased activity of C3 protein] | affects cotreatment|affects reaction|increases activity|increases cleavage | 11724962 |
| C016310 | cobra venom factor | [cobra venom factor co-treated with Magnesium] results in increased cleavage of and results in increased activity of C3 protein | affects cotreatment|increases activity|increases cleavage | 11724962 |
| C016310 | cobra venom factor | cobra venom factor inhibits the reaction [Ozone results in increased expression of C3 protein] | decreases reaction|increases expression | 14701711 |
| C016310 | cobra venom factor | cobra venom factor results in decreased expression of C3 protein | decreases expression | 11724962 |
| C016310 | cobra venom factor | cobra venom factor results in increased cleavage of and results in increased activity of C3 protein | increases activity|increases cleavage | 17916747 |
| D003474 | Curcumin | Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C3 mRNA] | decreases reaction|increases expression | 18200517 |
| D016572 | Cyclosporine | Cyclosporine results in decreased expression of C3 mRNA | decreases expression | 20106945 |
| C004742 | daidzein | daidzein results in increased expression of C3 mRNA | increases expression | 10822019 |
| D003907 | Dexamethasone | Dexamethasone promotes the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | increases expression|increases reaction | 11566438 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of C3 mRNA | decreases expression | 18042831 |
| D004054 | Diethylstilbestrol | Diethylstilbestrol results in increased expression of C3 mRNA | increases expression | 15289156 12370124 |
| D004054 | Diethylstilbestrol | Diethylstilbestrol results in increased expression of C3 protein | increases expression | 11390168 |
| D004054 | Diethylstilbestrol | Diethylstilbestrol results in increased expression of C3 mRNA | increases expression | 17011747 |
| D004726 | Endosulfan | Endosulfan results in decreased expression of C3 mRNA | decreases expression | 18790044 |
| D004958 | Estradiol | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of C3 mRNA | affects cotreatment|increases expression | 19619570 |
| D004958 | Estradiol | Estradiol results in increased expression of C3 mRNA | increases expression | 19619570 |
| D004958 | Estradiol | Estradiol affects the expression of C3 mRNA | affects expression | 15598610 |
| D004958 | Estradiol | Estradiol inhibits the reaction [Lipopolysaccharides results in increased expression of C3 mRNA] | decreases reaction|increases expression | 16977382 |
| D004958 | Estradiol | Estradiol results in increased expression of C3 mRNA | increases expression | 12370124 15289156 16985261 |
| D004958 | Estradiol | Estradiol results in increased expression of C3 protein | increases expression | 11390168 |
| D004958 | Estradiol | Estradiol affects the expression of C3 mRNA | affects expression | 18790044 |
| D004958 | Estradiol | Estradiol results in increased expression of C3 mRNA | increases expression | 15458795 11086226 15456929 16522720 |
| D004958 | Estradiol | Estradiol results in increased expression of C3 protein | increases expression | 11086226 |
| D004958 | Estradiol | Genistein inhibits the reaction [Estradiol affects the expression of C3 mRNA] | affects expression|decreases reaction | 17049845 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol affects the expression of C3 mRNA | affects expression | 17555576 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in decreased expression of C3 mRNA | decreases expression | 17942748 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of C3 mRNA | increases expression | 16174780 19400957 |
| D004997 | Ethinyl Estradiol | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of C3 mRNA | affects cotreatment|decreases expression | 17942748 |
| D004997 | Ethinyl Estradiol | Dexamethasone promotes the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | increases expression|increases reaction | 11566438 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol affects the expression of C3 mRNA | affects expression | 17351261 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of C3 mRNA | increases expression | 17557909 11331651 16174780 16140622 19400957 12399409 12117614 10822019 16639590 15834898 16551644 12655037 11566438 |
| D004997 | Ethinyl Estradiol | fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | decreases reaction|increases expression | 16639590 |
| D004997 | Ethinyl Estradiol | Levonorgestrel inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | decreases reaction|increases expression | 11566438 |
| D004997 | Ethinyl Estradiol | Medroxyprogesterone Acetate inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | decreases reaction|increases expression | 11566438 |
| D004997 | Ethinyl Estradiol | Mifepristone inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA]] | decreases reaction|increases expression | 11566438 16806946 |
| D004997 | Ethinyl Estradiol | Mifepristone promotes the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | increases expression|increases reaction | 11566438 |
| D004997 | Ethinyl Estradiol | Progesterone inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | decreases reaction|increases expression | 11566438 |
| D004997 | Ethinyl Estradiol | trimegestone inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | decreases reaction|increases expression | 11566438 |
| D015025 | Zearalenone | Zearalenone results in increased expression of C3 mRNA | increases expression | 17557909 |
| D005485 | Flutamide | Flutamide results in increased expression of C3 mRNA | increases expression | 17420220 |
| D005485 | Flutamide | [vinclozolin co-treated with procymidone co-treated with Flutamide] results in increased expression of C3 mRNA | affects cotreatment|increases expression | 17420220 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | decreases reaction|increases expression | 16639590 |
| C070081 | fulvestrant | fulvestrant results in increased expression of C3 mRNA | increases expression | 11086226 |
| C070081 | fulvestrant | fulvestrant results in increased expression of C3 protein | increases expression | 11086226 |
| C039281 | furan | furan results in decreased expression of C3 mRNA | decreases expression | 15120968 |
| D019833 | Genistein | Genistein results in increased expression of C3 mRNA | increases expression | 15289156 16985261 |
| D019833 | Genistein | Genistein inhibits the reaction [Estradiol affects the expression of C3 mRNA] | affects expression|decreases reaction | 17049845 |
| D019833 | Genistein | Genistein results in increased expression of C3 mRNA | increases expression | 11331651 |
| C029424 | hydrazine | hydrazine results in increased expression of C3 mRNA | increases expression | 15282401 |
| D007052 | Ibuprofen | Ibuprofen affects the expression of C3 mRNA | affects expression | 17070997 |
| D008070 | Lipopolysaccharides | CFP gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of C3 protein] | decreases reaction|increases expression | 17916747 |
| D008070 | Lipopolysaccharides | Estradiol inhibits the reaction [Lipopolysaccharides results in increased expression of C3 mRNA] | decreases reaction|increases expression | 16977382 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides results in increased expression of C3 mRNA | increases expression | 16977382 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides results in increased expression of C3 protein | increases expression | 17916747 |
| D008274 | Magnesium | CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium] results in increased cleavage of and results in increased activity of C3 protein] | affects cotreatment|affects reaction|increases activity|increases cleavage | 11724962 |
| D008274 | Magnesium | [cobra venom factor co-treated with Magnesium] results in increased cleavage of and results in increased activity of C3 protein | affects cotreatment|increases activity|increases cleavage | 11724962 |
| C013592 | mangiferin | mangiferin results in decreased expression of C3 mRNA | decreases expression | 15135318 |
| D017258 | Medroxyprogesterone Acetate | Medroxyprogesterone Acetate inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | decreases reaction|increases expression | 11566438 |
| D017258 | Medroxyprogesterone Acetate | Mifepristone inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA]] | decreases reaction|increases expression | 11566438 16806946 |
| D016210 | Methacholine Chloride | C3 protein affects the susceptibility to [Ozone co-treated with Methacholine Chloride] | affects cotreatment|affects response to substance | 14701711 |
| D008731 | Methoxychlor | Methoxychlor metabolite results in increased expression of C3 protein | increases expression | 11390168 |
| D008731 | Methoxychlor | Methoxychlor results in increased expression of C3 protein | increases expression | 11390168 |
| D008748 | Methylcholanthrene | Methylcholanthrene results in increased expression of C3 mRNA | increases expression | 16257430 |
| D015735 | Mifepristone | Mifepristone inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA]] | decreases reaction|increases expression | 16806946 11566438 |
| D015735 | Mifepristone | Mifepristone promotes the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | increases expression|increases reaction | 11566438 |
| D009151 | Mustard Gas | Mustard Gas results in increased expression of C3 protein | increases expression | 15953574 |
| D009151 | Mustard Gas | Mustard Gas results in increased expression of C3 mRNA | increases expression | 18988085 |
| C025256 | nonylphenol | nonylphenol results in increased expression of C3 protein | increases expression | 11390168 |
| C025256 | nonylphenol | nonylphenol results in increased expression of C3 mRNA | increases expression | 11086226 |
| C025256 | nonylphenol | nonylphenol results in increased expression of C3 protein | increases expression | 11086226 |
| D016912 | Levonorgestrel | Levonorgestrel inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | decreases reaction|increases expression | 11566438 |
| C016340 | o,p'-DDT | o,p'-DDT results in increased expression of C3 protein | increases expression | 11390168 |
| C016340 | o,p'-DDT | o,p'-DDT results in increased expression of C3 mRNA | increases expression | 10822019 11086226 |
| C016340 | o,p'-DDT | o,p'-DDT results in increased expression of C3 protein | increases expression | 11086226 |
| D010126 | Ozone | C3 protein affects the susceptibility to [Ozone co-treated with Methacholine Chloride] | affects cotreatment|affects response to substance | 14701711 |
| D010126 | Ozone | cobra venom factor inhibits the reaction [Ozone results in increased expression of C3 protein] | decreases reaction|increases expression | 14701711 |
| D010126 | Ozone | Ozone results in increased expression of C3 protein | increases expression | 14701711 |
| D010126 | Ozone | Ozone results in decreased expression of C3 mRNA | decreases expression | 16716893 |
| C041786 | palm oil | palm oil results in decreased expression of C3 mRNA | decreases expression | 18042831 |
| D010634 | Phenobarbital | Phenobarbital affects the expression of C3 protein | affects expression | 16099942 |
| C006253 | pirinixic acid | pirinixic acid affects the expression of C3 protein | affects expression | 16099942 |
| C025299 | polyphenols | polyphenols results in decreased expression of C3 mRNA | decreases expression | 16293270 |
| C035988 | procymidone | procymidone results in increased expression of C3 mRNA | increases expression | 17420220 |
| C035988 | procymidone | [vinclozolin co-treated with procymidone co-treated with Flutamide] results in increased expression of C3 mRNA | affects cotreatment|increases expression | 17420220 |
| D011374 | Progesterone | Progesterone inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | decreases reaction|increases expression | 11566438 |
| C467746 | propyl pyrazole triol | propyl pyrazole triol results in increased expression of C3 mRNA | increases expression | 12399409 |
| D020849 | Raloxifene | Raloxifene results in increased expression of C3 mRNA | increases expression | 12370124 |
| C539676 | rEV576 protein, tick | rEV576 protein, tick affects the expression of and affects the activity of C3 protein | affects activity|affects expression | 17215252 |
| C116926 | rofecoxib | rofecoxib results in increased expression of C3 mRNA | increases expression | 17070997 |
| C017947 | sodium arsenite | sodium arsenite results in decreased expression of C3 mRNA | decreases expression | 19590694 |
| C017947 | sodium arsenite | sodium arsenite affects the expression of C3 mRNA | affects expression | 17450228 |
| D013629 | Tamoxifen | Tamoxifen affects the expression of C3 mRNA | affects expression | 17555576 |
| D013629 | Tamoxifen | Tamoxifen results in increased expression of C3 mRNA | increases expression | 12370124 19400957 |
| D013629 | Tamoxifen | Tamoxifen results in increased expression of C3 protein | increases expression | 11390168 |
| D013629 | Tamoxifen | Tamoxifen results in increased expression of C3 mRNA | increases expression | 19400957 |
| D013749 | Tetrachlorodibenzodioxin | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of C3 mRNA | affects cotreatment|increases expression | 19619570 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of C3 mRNA | decreases expression | 19619570 |
| D013749 | Tetrachlorodibenzodioxin | AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of C3 mRNA] | decreases expression|decreases reaction | 14728982 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of C3 mRNA | affects cotreatment|decreases expression | 17942748 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of C3 mRNA | decreases expression | 14728982 |
| C050319 | trimegestone | trimegestone inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] | decreases reaction|increases expression | 11566438 |
| C015559 | trimellitic anhydride | trimellitic anhydride results in increased expression of C3 mRNA | increases expression | 16141432 |
| D014302 | Trinitrobenzenesulfonic Acid | Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C3 mRNA] | decreases reaction|increases expression | 18200517 |
| D014302 | Trinitrobenzenesulfonic Acid | Trinitrobenzenesulfonic Acid results in increased expression of C3 mRNA | increases expression | 18200517 17982090 |
| C025643 | vinclozolin | [vinclozolin co-treated with procymidone co-treated with Flutamide] results in increased expression of C3 mRNA | affects cotreatment|increases expression | 17420220 |
| D002762 | Cholecalciferol | Cholecalciferol results in increased expression of C3 mRNA | increases expression | 17170073 |
| D019287 | Zinc Sulfate | [Zinc Sulfate co-treated with CR1L protein] results in increased expression of C3 protein | affects cotreatment|increases expression | 15086380 |
| D015054 | Zymosan | CD55 protein affects the reaction [Zymosan results in increased activity of C3 protein] | affects reaction|increases activity | 9892684 |
| D015054 | Zymosan | CFB gene mutant form inhibits the reaction [Zymosan results in increased expression of C3 protein] | decreases reaction|increases expression | 17916747 |
| D015054 | Zymosan | Zymosan results in increased activity of C3 protein | increases activity | 9892684 |
| D015054 | Zymosan | Zymosan results in increased expression of C3 protein | increases expression | 17916747 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000008 | Abdominal Neoplasms | Tamoxifen | 3.85 | 14745880 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Phenobarbital | 6.05 | 6195326 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Tetrachlorodibenzodioxin | 6.05 | 15322242 11752688 14514962 | |
| MESH:D000138 | Acidosis | Ammonium Chloride | 8.35 | 18287403 | |
| MESH:D000138 | Acidosis | Zinc Sulfate | 8.35 | 7265320 | |
| MESH:D000152 | Acne Vulgaris | Ethinyl Estradiol | 3.24 | 17505938 | |
| MESH:D058186 | Acute Kidney Injury | Ibuprofen | 3.84 | 6375363 | |
| MESH:D055371 | Acute Lung Injury | Lipopolysaccharides | 6.94 | 18653653 11850527 | |
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 6.94 | 18653653 | |
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 14.04 | 20127859 20464547 | |
| MESH:D000230 | Adenocarcinoma | daidzein | 14.04 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Estradiol | 14.04 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Ethinyl Estradiol | 14.04 | 14692618 | |
| MESH:D000230 | Adenocarcinoma | Genistein | 14.04 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Ibuprofen | 14.04 | 10697514 | |
| MESH:D000236 | Adenoma | 4,4'-diaminodiphenylmethane | 12.45 | 3712494 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 12.45 | 6695378 | |
| MESH:D000236 | Adenoma | Magnesium | 12.45 | 17823441 | |
| MESH:D000236 | Adenoma | Methylcholanthrene | 12.45 | 10545420 6695378 | |
| MESH:D018248 | Adenoma, Liver Cell | Phenobarbital | 13.34 | 17620307 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 13.34 | 16434500 | |
| MESH:D018248 | Adenoma, Liver Cell | Tetrachlorodibenzodioxin | 13.34 | 16835633 | |
| MESH:D000310 | Adrenal Gland Neoplasms | sodium arsenite | 4.00 | 15276417 | |
| MESH:D018246 | Adrenocortical Adenoma | sodium arsenite | 4.20 | 16712894 17306315 | |
| MESH:D000419 | Albuminuria | Raloxifene | 3.94 | 17451421 17308373 | |
| MESH:D019973 | Alcohol-Related Disorders | Curcumin | 4.38 | 17887948 | |
| MESH:D000544 | Alzheimer Disease | Androgens | 10.25 | 17917157 17182789 | |
| MESH:D000544 | Alzheimer Disease | Curcumin | 10.25 | 15590663 | |
| MESH:D000544 | Alzheimer Disease | Ibuprofen | 10.25 | 18351690 | |
| MESH:D000544 | Alzheimer Disease | Ozone | 10.25 | 15513908 | |
| MESH:D000544 | Alzheimer Disease | Raloxifene | 10.25 | 15800139 | |
| MESH:D000686 | Amyloidosis | Diethylstilbestrol | 3.83 | 15469931 | |
| MESH:D000707 | Anaphylaxis | Ibuprofen | 9.87 | 9532969 | |
| MESH:D000707 | Anaphylaxis | mangiferin | 9.87 | 16536907 14669257 | |
| MESH:D000740 | Anemia | Tetrachlorodibenzodioxin | 7.00 | 11748828 | |
| MESH:D000740 | Anemia | Zymosan | 7.00 | 18664788 | |
| MESH:D000799 | Angioedema | Acetaminophen | 3.15 | 10982225 | |
| MESH:D000860 | Anoxia | Zinc Sulfate | 4.34 | 7265320 | |
| MESH:D001008 | Anxiety Disorders | vinclozolin | 3.08 | 19015723 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 3.40 | 19183758 | |
| MESH:D001161 | Arteriosclerosis | Dietary Fats | 7.69 | 15238619 | |
| MESH:D001161 | Arteriosclerosis | Ethinyl Estradiol | 7.69 | 11256880 | |
| MESH:D001169 | Arthritis, Experimental | Dexamethasone | 13.85 | 17659584 | |
| MESH:D001169 | Arthritis, Experimental | Ethinyl Estradiol | 13.85 | 15885639 | |
| MESH:D001169 | Arthritis, Experimental | rofecoxib | 13.85 | 16690336 | |
| MESH:D001169 | Arthritis, Experimental | Zymosan | 13.85 | 17659584 15142272 16872482 15188379 15944321 | |
| MESH:D001172 | Arthritis, Rheumatoid | Curcumin | 4.11 | 16807698 | |
| MESH:D001172 | Arthritis, Rheumatoid | Ozone | 4.11 | 15570426 | |
| MESH:D001249 | Asthma | Mustard Gas | 6.58 | 10378619 | |
| MESH:D001249 | Asthma | Ozone | 6.58 | 17854713 16373670 | |
| MESH:D001249 | Asthma | trimellitic anhydride | 6.58 | 16141432 | |
| MESH:D050197 | Atherosclerosis | Curcumin | 8.64 | 18704882 | |
| MESH:D050197 | Atherosclerosis | mangiferin | 8.64 | 18450471 | |
| MESH:D050197 | Atherosclerosis | Methylcholanthrene | 8.64 | 11922910 | |
| MESH:D001284 | Atrophy | fulvestrant | 4.20 | 11514358 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 2.46 | 18445737 | |
| MESH:D001321 | Autistic Disorder | Magnesium | 2.46 | 16846101 | |
| MESH:D001327 | Autoimmune Diseases | Cholecalciferol | 8.87 | 16142846 | |
| MESH:D001327 | Autoimmune Diseases | Curcumin | 8.87 | 19761891 | |
| MESH:D001660 | Biliary Tract Diseases | 4,4'-diaminodiphenylmethane | 4.32 | 1440618 11289319 | |
| MESH:D001768 | Blister | Mustard Gas | 4.47 | 19167455 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 6.72 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | Tetrachlorodibenzodioxin | 6.72 | 12125929 | |
| MESH:D001836 | Body Weight Changes | Tetrachlorodibenzodioxin | 3.09 | 15340226 | |
| MESH:D001848 | Bone Diseases, Developmental | Tetrachlorodibenzodioxin | 2.29 | 15746008 | |
| MESH:D001862 | Bone Resorption | bisphenol A | 7.82 | 11985600 | |
| MESH:D001862 | Bone Resorption | mangiferin | 7.82 | 9881647 | |
| MESH:D020201 | Brain Hemorrhage, Traumatic | Progesterone | 4.64 | 17868700 | |
| MESH:D001930 | Brain Injuries | Progesterone | 8.74 | 15845082 15665606 15380490 | |
| MESH:D001930 | Brain Injuries | Raloxifene | 8.74 | 16580743 | |
| MESH:D002545 | Brain Ischemia | Curcumin | 8.28 | 16770732 | |
| MESH:D002545 | Brain Ischemia | Ibuprofen | 8.28 | 15837124 | |
| MESH:D001932 | Brain Neoplasms | Curcumin | 3.34 | 17596214 | |
| MESH:D001943 | Breast Neoplasms | Androgens | 12.34 | 17018787 | |
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 12.34 | 20146248 17474063 | |
| MESH:D001943 | Breast Neoplasms | bexarotene | 12.34 | 16344269 16818667 | |
| MESH:D001943 | Breast Neoplasms | bisphenol A | 12.34 | 17123778 | |
| MESH:D001943 | Breast Neoplasms | Curcumin | 12.34 | 19250217 16243823 18593918 18462866 | |
| MESH:D001943 | Breast Neoplasms | Dietary Fats | 12.34 | 20435547 | |
| MESH:D001943 | Breast Neoplasms | Diethylstilbestrol | 12.34 | 17129689 15324884 | |
| MESH:D001943 | Breast Neoplasms | Estradiol | 12.34 | 16675129 17018787 12948864 14630087 17289903 19861407 17261762 18497071 | |
| MESH:D001943 | Breast Neoplasms | fulvestrant | 12.34 | 18984771 | |
| MESH:D001943 | Breast Neoplasms | Genistein | 12.34 | 17200150 16873071 16541309 | |
| MESH:D001943 | Breast Neoplasms | Methylcholanthrene | 12.34 | 17474063 | |
| MESH:D001943 | Breast Neoplasms | Progesterone | 12.34 | 15562024 16175315 17614352 | |
| MESH:D001943 | Breast Neoplasms | Raloxifene | 12.34 | 17242785 15572757 16837676 17893378 17595753 15758505 17261762 16912660 17952589 17440819 17049068 15775269 | |
| MESH:D001943 | Breast Neoplasms | Tamoxifen | 12.34 | 20065188 19189212 18821012 19189210 18997820 21138602 19289846 18351453 19288272 18855134 17242785 17893378 20859285 20544844 18425577 15565566 20005174 19011961 16818667 17440819 18984771 19410462 20390343 16873071 21152245 15668708 19066611 19221464 17261762 16202921 19200415 17049068 18629630 18815881 19155303 19487384 20135344 19115204 19142967 19084267 19244106 19059307 16273361 11161223 19103187 | |
| MESH:D001943 | Breast Neoplasms | Tetrachlorodibenzodioxin | 12.34 | 20435547 | |
| MESH:D016535 | Bronchial Hyperreactivity | Ozone | 3.12 | 15516495 18315731 18417511 14754758 16777450 17626835 19059883 | |
| MESH:D001989 | Bronchiolitis Obliterans | Mustard Gas | 4.47 | 15286001 | |
| MESH:D029481 | Bronchitis, Chronic | Mustard Gas | 4.28 | 10378619 17687719 | |
| MESH:D002100 | Cachexia | Ibuprofen | 10.29 | 15141370 | |
| MESH:D002100 | Cachexia | Ozone | 10.29 | 16183385 | |
| MESH:D002181 | Candidiasis, Vulvovaginal | Estradiol | 3.78 | 16111702 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 3.11 | 3786805 15673190 16124888 16227642 16011737 16050911 10355542 15700767 18705752 16192424 16097048 15721981 | |
| MESH:D002277 | Carcinoma | Curcumin | 10.81 | 18593918 | |
| MESH:D002277 | Carcinoma | Methylcholanthrene | 10.81 | 10545420 | |
| MESH:D002277 | Carcinoma | Tetrachlorodibenzodioxin | 10.81 | 16835633 | |
| MESH:D018270 | Carcinoma, Ductal, Breast | Tamoxifen | 3.83 | 19066611 | |
| MESH:D006528 | Carcinoma, Hepatocellular | 4,4'-diaminodiphenylmethane | 16.61 | 7296757 3581430 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 16.61 | 3084413 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 16.61 | 18788625 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Diethylstilbestrol | 16.61 | 15948411 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estradiol | 16.61 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Genistein | 16.61 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Phenobarbital | 16.61 | 17173139 1701930 20007298 20935162 6705139 | |
| MESH:D006528 | Carcinoma, Hepatocellular | sodium arsenite | 16.61 | 15276417 17306315 16507464 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tamoxifen | 16.61 | 16924424 | |
| MESH:D002278 | Carcinoma in Situ | bisphenol A | 4.30 | 17123778 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | bexarotene | 4.86 | 16247446 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | Curcumin | 4.86 | 18414057 | |
| MESH:D002292 | Carcinoma, Renal Cell | 4,4'-diaminodiphenylmethane | 2.31 | 7296757 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 6.05 | 20419170 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Curcumin | 6.05 | 18462866 | |
| MESH:D002294 | Carcinoma, Squamous Cell | sodium arsenite | 6.05 | 18572023 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Raloxifene | 7.50 | 17572228 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Tamoxifen | 7.50 | 17572228 | |
| MESH:D006332 | Cardiomegaly | Tetrachlorodibenzodioxin | 1.95 | 18850075 18670907 16120746 | |
| MESH:D002318 | Cardiovascular Diseases | daidzein | 9.45 | 16332659 | |
| MESH:D002318 | Cardiovascular Diseases | Genistein | 9.45 | 16332659 | |
| MESH:D002318 | Cardiovascular Diseases | Raloxifene | 9.45 | 15775269 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.14 | 10977129 | |
| MESH:D002471 | Cell Transformation, Neoplastic | 4,4'-diaminodiphenylmethane | 15.81 | 7505956 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Cyclosporine | 15.81 | 12371664 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Estradiol | 15.81 | 18566989 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Methylcholanthrene | 15.81 | 16192471 | |
| MESH:D002471 | Cell Transformation, Neoplastic | sodium arsenite | 15.81 | 20056578 19524636 | |
| MESH:D002493 | Central Nervous System Diseases | Phenobarbital | 3.58 | 4080065 | |
| MESH:D018281 | Cholangiocarcinoma | Tetrachlorodibenzodioxin | 2.57 | 16835633 | |
| MESH:D002779 | Cholestasis | 4,4'-diaminodiphenylmethane | 19.71 | 9022650 19486331 | |
| MESH:D002779 | Cholestasis | Cyclosporine | 19.71 | 19486331 | |
| MESH:D002779 | Cholestasis | Ethinyl Estradiol | 19.71 | 17333356 11677210 16919318 17110522 17681005 15861022 16105132 | |
| MESH:D002779 | Cholestasis | Levonorgestrel | 19.71 | 15861022 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 19.71 | 19176532 | |
| MESH:D002972 | Cleft Palate | Tetrachlorodibenzodioxin | 1.77 | 16354765 12621046 8697196 15668235 15340226 | |
| MESH:D003072 | Cognition Disorders | Raloxifene | 3.95 | 15800139 | |
| MESH:D003092 | Colitis | Curcumin | 7.74 | 16804969 16782535 18200517 | |
| MESH:D003092 | Colitis | Trinitrobenzenesulfonic Acid | 7.74 | 16782535 17991707 16474422 16867261 18023891 16804969 18200517 17936198 11698051 | |
| MESH:D003093 | Colitis, Ulcerative | Trinitrobenzenesulfonic Acid | 3.16 | 17276891 | |
| MESH:D003103 | Coloboma | Curcumin | 3.93 | 18809619 | |
| MESH:D003110 | Colonic Neoplasms | Curcumin | 9.12 | 19359593 16340194 | |
| MESH:D003110 | Colonic Neoplasms | Dexamethasone | 9.12 | 15824018 | |
| MESH:D003110 | Colonic Neoplasms | Genistein | 9.12 | 17182828 | |
| MESH:D003110 | Colonic Neoplasms | polyphenols | 9.12 | 16293270 | |
| MESH:D003110 | Colonic Neoplasms | rofecoxib | 9.12 | 12902858 | |
| MESH:D003111 | Colonic Polyps | Magnesium | 5.40 | 17823441 | |
| MESH:D015179 | Colorectal Neoplasms | Magnesium | 3.45 | 17823441 | |
| MESH:D000013 | Congenital Abnormalities | Tetrachlorodibenzodioxin | 2.47 | 14669216 17141729 | |
| MESH:D016510 | Corneal Neovascularization | Curcumin | 4.23 | 18497527 | |
| MESH:D019465 | Craniofacial Abnormalities | Dexamethasone | 2.33 | 17728286 | |
| MESH:D019465 | Craniofacial Abnormalities | Tetrachlorodibenzodioxin | 2.33 | 15322242 20055451 10048152 | |
| MESH:D016638 | Critical Illness | Androgens | 5.37 | 16670151 | |
| MESH:D003456 | Cryptorchidism | Diethylstilbestrol | 9.20 | 16002989 12952375 | |
| MESH:D003456 | Cryptorchidism | vinclozolin | 9.20 | 14966744 | |
| MESH:D003457 | Cryptosporidiosis | mangiferin | 5.16 | 16547730 | |
| MESH:D003490 | Cyanosis | Endosulfan | 4.87 | 7900959 | |
| MESH:D003711 | Demyelinating Diseases | Tamoxifen | 3.69 | 19031437 | |
| MESH:D003865 | Depressive Disorder, Major | Raloxifene | 3.57 | 17474826 | |
| MESH:D017449 | Dermatitis, Allergic Contact | 4,4'-diaminodiphenylmethane | 4.90 | 2524372 18759878 11906362 11298694 12868966 8156756 14531868 8970840 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Dexamethasone | 4.90 | 12438553 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.06 | 18249437 | |
| MESH:D003877 | Dermatitis, Contact | 4,4'-diaminodiphenylmethane | 2.86 | 2952479 3621924 | |
| MESH:D002658 | Developmental Disabilities | Magnesium | 4.42 | 16846101 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | mangiferin | 4.03 | 19028559 12093613 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Curcumin | 11.19 | 18403477 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | daidzein | 11.19 | 16647724 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Genistein | 11.19 | 16647724 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | mangiferin | 11.19 | 11315760 9881663 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Tetrachlorodibenzodioxin | 11.19 | 17107852 | |
| MESH:D003928 | Diabetic Nephropathies | Curcumin | 21.90 | 18204486 | |
| MESH:D003928 | Diabetic Nephropathies | Estradiol | 21.90 | 19279558 | |
| MESH:D003928 | Diabetic Nephropathies | mangiferin | 21.90 | 19960420 19706694 | |
| MESH:D003928 | Diabetic Nephropathies | Raloxifene | 21.90 | 15920148 17451421 17308373 | |
| MESH:D003928 | Diabetic Nephropathies | Tamoxifen | 21.90 | 19279558 | |
| MESH:D003929 | Diabetic Neuropathies | Progesterone | 3.82 | 17187935 | |
| MESH:D003967 | Diarrhea | Dexamethasone | 3.07 | 7237001 | |
| MESH:D056486 | Drug-Induced Liver Injury | marker/mechanism | 16099942 | ||
| MESH:D056486 | Drug-Induced Liver Injury | 4,4'-diaminodiphenylmethane | 9.17 | 7440962 18289764 1440618 18692083 9653073 9022650 9328219 18648102 6679447 6482804 16192314 8291058 11289319 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 9.17 | 15968718 17562736 12705907 12958197 16177239 19370779 11739529 12594235 10915739 11834606 11743745 19164858 11287661 16485898 11461765 19923254 19739265 16227642 19416960 14986274 18713872 16109766 17906064 17522070 19085960 11421492 18071297 2444490 16081117 16393943 14725611 14550746 16781746 10774834 12153990 12540782 12392966 11529661 19420014 15619225 10663392 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 9.17 | 15968718 3732212 16177239 7120509 17522070 6623471 11566570 3786805 9327722 15998439 19336974 10092053 19085960 15027814 16227642 10915739 7440962 2869522 4309450 21278145 7179309 6884620 | |
| MESH:D056486 | Drug-Induced Liver Injury | polyphenols | 9.17 | 19370779 | |
| MESH:D056486 | Drug-Induced Liver Injury | Tetrachlorodibenzodioxin | 9.17 | 20420201 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 3.40 | 19426721 | |
| MESH:D004362 | Drug Toxicity | Tetrachlorodibenzodioxin | 2.24 | 11462148 | |
| MESH:D004374 | Ductus Arteriosus, Patent | Ibuprofen | 4.93 | 18446180 18450898 16133044 | |
| MESH:D004381 | Duodenal Ulcer | Curcumin | 3.40 | 17351913 | |
| MESH:D050171 | Dyslipidemias | Dietary Fats | 2.94 | 18367378 | |
| MESH:D004417 | Dyspnea | Endosulfan | 4.58 | 7900959 3388749 | |
| MESH:D004421 | Dystonia | Phenobarbital | 3.37 | 1851702 | |
| MESH:D004485 | Eczema | Dexamethasone | 3.81 | 12438553 | |
| MESH:D004487 | Edema | Dexamethasone | 19.16 | 19703484 | |
| MESH:D004487 | Edema | Mustard Gas | 19.16 | 11428647 11428631 11402378 9260866 | |
| MESH:D004487 | Edema | pirinixic acid | 19.16 | 12083418 | |
| MESH:D004487 | Edema | Raloxifene | 19.16 | 15860553 | |
| MESH:D004487 | Edema | Tetrachlorodibenzodioxin | 19.16 | 11000095 12711302 | |
| MESH:D004487 | Edema | Zymosan | 19.16 | 7907874 | |
| MESH:D004489 | Edema, Cardiac | Tetrachlorodibenzodioxin | 3.20 | 15322242 18230668 16714409 | |
| MESH:D004646 | Emphysema | Endosulfan | 5.85 | 7900959 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Ethinyl Estradiol | 16.61 | 12538720 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Progesterone | 16.61 | 17692515 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Raloxifene | 16.61 | 15845917 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Tamoxifen | 16.61 | 19031437 | |
| MESH:D004714 | Endometrial Hyperplasia | Diethylstilbestrol | 9.62 | 16402032 | |
| MESH:D004714 | Endometrial Hyperplasia | Genistein | 9.62 | 16402032 | |
| MESH:D016889 | Endometrial Neoplasms | 4-hydroxytamoxifen | 22.90 | 19148513 | |
| MESH:D016889 | Endometrial Neoplasms | daidzein | 22.90 | 11473722 | |
| MESH:D016889 | Endometrial Neoplasms | Diethylstilbestrol | 22.90 | 15700306 16804899 | |
| MESH:D016889 | Endometrial Neoplasms | Estradiol | 22.90 | 19148513 18566989 11473722 | |
| MESH:D016889 | Endometrial Neoplasms | Genistein | 22.90 | 11473722 | |
| MESH:D016889 | Endometrial Neoplasms | Tamoxifen | 22.90 | 20544844 19155303 17893378 16202921 | |
| MESH:D004715 | Endometriosis | Ibuprofen | 22.28 | 15652904 | |
| MESH:D004715 | Endometriosis | Mifepristone | 22.28 | 16134523 | |
| MESH:D004715 | Endometriosis | Progesterone | 22.28 | 16134523 | |
| MESH:D004715 | Endometriosis | rofecoxib | 22.28 | 15652904 | |
| MESH:D004715 | Endometriosis | Tetrachlorodibenzodioxin | 22.28 | 9294722 10568697 | |
| MESH:D019446 | Endotoxemia | Ibuprofen | 8.55 | 11545620 | |
| MESH:D019446 | Endotoxemia | Lipopolysaccharides | 8.55 | 15328337 17637181 15821434 | |
| MESH:D004831 | Epilepsies, Myoclonic | Phenobarbital | 3.44 | 3659116 | |
| MESH:D004828 | Epilepsies, Partial | Phenobarbital | 3.18 | 11558140 3922381 | |
| MESH:D004827 | Epilepsy | Phenobarbital | 2.50 | 20417680 | |
| MESH:D004832 | Epilepsy, Absence | Phenobarbital | 2.96 | 6401628 | |
| MESH:D017029 | Epilepsy, Complex Partial | Phenobarbital | 3.58 | 7750514 | |
| MESH:D004830 | Epilepsy, Tonic-Clonic | Phenobarbital | 3.34 | 3659116 | |
| MESH:D007172 | Erectile Dysfunction | daidzein | 4.37 | 14972507 | |
| MESH:D004890 | Erythema | Mustard Gas | 4.47 | 9357497 | |
| MESH:D004938 | Esophageal Neoplasms | 4,4'-diaminodiphenylmethane | 3.59 | 3581430 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 3.59 | 16530937 | |
| MESH:D005124 | Eye Abnormalities | Tetrachlorodibenzodioxin | 2.48 | 11564622 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 37.69 | 16239168 19224547 15959796 61145 12631006 17595544 12795759 16045604 | |
| MESH:D005234 | Fatty Liver | Curcumin | 37.69 | 19297423 | |
| MESH:D005234 | Fatty Liver | Cyclosporine | 37.69 | 19224547 | |
| MESH:D005234 | Fatty Liver | Dietary Fats | 37.69 | 19551842 18296743 17967931 19004024 | |
| MESH:D005234 | Fatty Liver | Ethinyl Estradiol | 37.69 | 15345470 | |
| MESH:D005234 | Fatty Liver | mangiferin | 37.69 | 15975614 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 37.69 | 19236843 20131406 | |
| MESH:D005234 | Fatty Liver | Raloxifene | 37.69 | 17473493 | |
| MESH:D005234 | Fatty Liver | Tamoxifen | 37.69 | 14986274 19224547 | |
| MESH:D052776 | Female Urogenital Diseases | Diethylstilbestrol | 6.69 | 16611131 16513791 15751030 16002989 16534752 | |
| MESH:D052776 | Female Urogenital Diseases | Tamoxifen | 6.69 | 16709447 | |
| MESH:D005313 | Fetal Death | Tetrachlorodibenzodioxin | 2.79 | 11858732 | |
| MESH:D005334 | Fever | Ibuprofen | 7.53 | 16997862 | |
| MESH:D005334 | Fever | Lipopolysaccharides | 7.53 | 9205823 11852909 | |
| MESH:D005350 | Fibroma | 4,4'-diaminodiphenylmethane | 4.32 | 6705139 | |
| MESH:D018221 | Fibromatosis, Abdominal | Tamoxifen | 3.84 | 14745880 | |
| MESH:D018222 | Fibromatosis, Aggressive | Tamoxifen | 3.50 | 19069698 | |
| MESH:D005354 | Fibrosarcoma | Methylcholanthrene | 4.25 | 14633661 10962813 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 25.92 | 18705752 | |
| MESH:D005355 | Fibrosis | Curcumin | 25.92 | 18705752 | |
| MESH:D005355 | Fibrosis | Cyclosporine | 25.92 | 12639820 12168785 | |
| MESH:D005355 | Fibrosis | Dietary Fats | 25.92 | 18296743 | |
| MESH:D005355 | Fibrosis | Tetrachlorodibenzodioxin | 25.92 | 20067830 | |
| MESH:D005355 | Fibrosis | Trinitrobenzenesulfonic Acid | 25.92 | 17994277 | |
| MESH:D005756 | Gastritis | Acetaminophen | 2.98 | 16983495 | |
| MESH:D005770 | Gastrointestinal Neoplasms | Curcumin | 4.02 | 18462866 | |
| MESH:D030342 | Genetic Diseases, Inborn | vinclozolin | 4.25 | 16973722 | |
| MESH:D005832 | Genital Diseases, Male | vinclozolin | 4.60 | 16417039 | |
| MESH:D005833 | Genital Neoplasms, Female | Diethylstilbestrol | 10.54 | 16452187 | |
| MESH:D005833 | Genital Neoplasms, Female | sodium arsenite | 10.54 | 16452187 | |
| MESH:D005885 | Gingival Hyperplasia | Cyclosporine | 3.53 | 8708960 | |
| MESH:D005909 | Glioblastoma | Curcumin | 5.79 | 17596214 | |
| MESH:D005909 | Glioblastoma | Genistein | 5.79 | 16598420 | |
| MESH:D006042 | Goiter | 4,4'-diaminodiphenylmethane | 3.40 | 7505956 | |
| MESH:D006058 | Gonadal Disorders | Tetrachlorodibenzodioxin | 3.89 | 10696789 | |
| MESH:D006258 | Head and Neck Neoplasms | Curcumin | 3.17 | 18462866 18829502 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 5.08 | 20471113 | |
| MESH:D006330 | Heart Defects, Congenital | Tetrachlorodibenzodioxin | 5.08 | 11294989 10048152 | |
| MESH:D006331 | Heart Diseases | mangiferin | 6.50 | 12093613 | |
| MESH:D006331 | Heart Diseases | Raloxifene | 6.50 | 11110106 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.09 | 20558911 | |
| MESH:D006457 | Hemoglobinuria, Paroxysmal | Cyclosporine | 3.73 | 15720958 | |
| MESH:D006463 | Hemolytic-Uremic Syndrome | Lipopolysaccharides | 3.78 | 16366002 | |
| OMIM:612925 | HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 5 | marker/mechanism | |||
| MESH:D006470 | Hemorrhage | Endosulfan | 8.39 | 7900959 | |
| MESH:D006470 | Hemorrhage | Tetrachlorodibenzodioxin | 8.39 | 11000095 | |
| MESH:D006505 | Hepatitis | 4,4'-diaminodiphenylmethane | 12.03 | 6705139 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 12.03 | 19900420 19110552 | |
| MESH:D006505 | Hepatitis | Zymosan | 12.03 | 19110552 | |
| MESH:D006527 | Hepatolenticular Degeneration | Zinc Sulfate | 4.33 | 17063115 | |
| MESH:D006529 | Hepatomegaly | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | 15.28 | 16109766 | |
| MESH:D006529 | Hepatomegaly | Phenobarbital | 15.28 | 16109766 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 15.28 | 19176532 16221962 18467677 19772884 | |
| MESH:D006529 | Hepatomegaly | Tetrachlorodibenzodioxin | 15.28 | 15340226 16120746 12621046 | |
| MESH:D015417 | Hereditary Sensory and Motor Neuropathy | Curcumin | 4.37 | 17701891 | |
| MESH:D006548 | Hernia, Diaphragmatic | Dexamethasone | 2.78 | 7520565 | |
| MESH:D006558 | Herpes Genitalis | Estradiol | 4.33 | 15709030 | |
| MESH:D006561 | Herpes Simplex | mangiferin | 4.33 | 10715843 | |
| MESH:D006628 | Hirsutism | Androgens | 5.38 | 16914592 17019078 | |
| MESH:D006689 | Hodgkin Disease | sodium arsenite | 2.59 | 12676792 | |
| MESH:D019584 | Hot Flashes | 8-prenylnaringenin | 8.48 | 17088409 | |
| MESH:D019584 | Hot Flashes | Estradiol | 8.48 | 17088409 | |
| MESH:D006869 | Hydronephrosis | Tetrachlorodibenzodioxin | 3.35 | 16354765 16959395 8697196 18606429 15340226 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 2.15 | 16870215 | |
| MESH:D017588 | Hyperandrogenism | Androgens | 10.07 | 17019078 | |
| MESH:D017588 | Hyperandrogenism | Flutamide | 10.07 | 15356085 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 3.85 | 16899240 | |
| MESH:D006937 | Hypercholesterolemia | Curcumin | 7.18 | 18704882 | |
| MESH:D006937 | Hypercholesterolemia | Dietary Fats | 7.18 | 21332399 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 2.58 | 20558911 | |
| MESH:D006946 | Hyperinsulinism | mangiferin | 4.42 | 11315760 9881663 | |
| MESH:D006949 | Hyperlipidemias | Dietary Fats | 7.49 | 21332399 | |
| MESH:D006949 | Hyperlipidemias | mangiferin | 7.49 | 15975614 | |
| MESH:D006965 | Hyperplasia | 4,4'-diaminodiphenylmethane | 8.61 | 15034207 | |
| MESH:D006965 | Hyperplasia | Diethylstilbestrol | 8.61 | 12960047 14722030 | |
| MESH:D006967 | Hypersensitivity | mangiferin | 4.10 | 16536907 | |
| MESH:D006973 | Hypertension | Cyclosporine | 12.99 | 10903974 | |
| MESH:D006973 | Hypertension | daidzein | 12.99 | 17169123 | |
| MESH:D006973 | Hypertension | Dexamethasone | 12.99 | 17042910 | |
| MESH:D006973 | Hypertension | Raloxifene | 12.99 | 17577099 15787275 | |
| MESH:D006973 | Hypertension | Tetrachlorodibenzodioxin | 12.99 | 18850075 18670907 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 3.42 | 15338365 | |
| MESH:D006984 | Hypertrophy | Ibuprofen | 4.36 | 16672835 | |
| MESH:D007021 | Hypospadias | Diethylstilbestrol | 9.02 | 16002989 | |
| MESH:D007021 | Hypospadias | Ethinyl Estradiol | 9.02 | 16945680 16569931 | |
| MESH:D007022 | Hypotension | Zinc Sulfate | 3.84 | 7265320 | |
| MESH:D007105 | Immune Complex Diseases | marker/mechanism | |||
| MESH:D007154 | Immune System Diseases | mangiferin | 5.16 | 16076520 | |
| MESH:D007235 | Infant, Premature, Diseases | Ibuprofen | 5.14 | 16133044 | |
| MESH:D020244 | Infarction, Middle Cerebral Artery | Progesterone | 3.73 | 15869954 | |
| MESH:D007246 | Infertility | Diethylstilbestrol | 3.70 | 15036965 | |
| MESH:D007247 | Infertility, Female | Ethinyl Estradiol | 2.83 | 12013081 | |
| MESH:D007248 | Infertility, Male | Endosulfan | 20.07 | 9432128 8588293 | |
| MESH:D007248 | Infertility, Male | Ethinyl Estradiol | 20.07 | 17937319 | |
| MESH:D007248 | Infertility, Male | fulvestrant | 20.07 | 11514358 | |
| MESH:D007248 | Infertility, Male | Methoxychlor | 20.07 | 11955947 16467254 | |
| MESH:D007248 | Infertility, Male | sodium arsenite | 20.07 | 15346721 12646999 | |
| MESH:D007248 | Infertility, Male | vinclozolin | 20.07 | 16467254 | |
| MESH:D007249 | Inflammation | Curcumin | 40.75 | 18403477 17151092 16956363 | |
| MESH:D007249 | Inflammation | Dexamethasone | 40.75 | 11099482 8960868 | |
| MESH:D007249 | Inflammation | Dietary Fats | 40.75 | 20412841 | |
| MESH:D007249 | Inflammation | Ibuprofen | 40.75 | 3291741 | |
| MESH:D007249 | Inflammation | Lipopolysaccharides | 40.75 | 17237260 17963957 12878042 9205823 17255318 | |
| MESH:D007249 | Inflammation | mangiferin | 40.75 | 15222974 | |
| MESH:D007249 | Inflammation | Methacholine Chloride | 40.75 | 18249437 | |
| MESH:D007249 | Inflammation | Mustard Gas | 40.75 | 11402378 9260866 11428647 11428620 16001271 9357497 11428631 17524151 8975870 | |
| MESH:D007249 | Inflammation | polyphenols | 40.75 | 16366677 | |
| MESH:D007249 | Inflammation | Progesterone | 40.75 | 15869954 | |
| MESH:D007249 | Inflammation | Tamoxifen | 40.75 | 19457130 | |
| MESH:D007249 | Inflammation | Tetrachlorodibenzodioxin | 40.75 | 12878042 12200463 | |
| MESH:D007249 | Inflammation | Zymosan | 40.75 | 11289658 8014878 | |
| MESH:D015212 | Inflammatory Bowel Diseases | Curcumin | 5.58 | 18596194 18200517 | |
| MESH:D015212 | Inflammatory Bowel Diseases | Trinitrobenzenesulfonic Acid | 5.58 | 18200517 | |
| MESH:D007333 | Insulin Resistance | bisphenol A | 18.11 | 16393666 | |
| MESH:D007333 | Insulin Resistance | Dietary Fats | 18.11 | 11836018 18457598 | |
| MESH:D007333 | Insulin Resistance | Estradiol | 18.11 | 16393666 16627594 | |
| MESH:D007333 | Insulin Resistance | mangiferin | 18.11 | 11315760 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 18.11 | 16306350 | |
| MESH:D007410 | Intestinal Diseases | rofecoxib | 8.24 | 15831440 | |
| MESH:D007410 | Intestinal Diseases | Trinitrobenzenesulfonic Acid | 8.24 | 17994277 | |
| MESH:D007414 | Intestinal Neoplasms | Curcumin | 3.62 | 10783313 | |
| MESH:D007417 | Intestinal Polyps | rofecoxib | 4.73 | 11245490 | |
| MESH:D019189 | Iron Metabolism Disorders | Lipopolysaccharides | 3.99 | 17255318 | |
| MESH:D043183 | Irritable Bowel Syndrome | Zymosan | 5.15 | 17553498 | |
| MESH:D007511 | Ischemia | mangiferin | 4.60 | 16806951 | |
| MESH:D007565 | Jaundice | 4,4'-diaminodiphenylmethane | 4.32 | 8074119 9022650 | |
| MESH:D007569 | Jaw Abnormalities | Tetrachlorodibenzodioxin | 2.72 | 16580747 | |
| MESH:D007638 | Keratoconjunctivitis Sicca | Cyclosporine | 3.74 | 15604871 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 14.43 | 15629191 12587719 | |
| MESH:D007674 | Kidney Diseases | Cyclosporine | 14.43 | 10903974 8314463 18776723 | |
| MESH:D007674 | Kidney Diseases | Estradiol | 14.43 | 15618244 | |
| MESH:D007674 | Kidney Diseases | mangiferin | 14.43 | 12093613 | |
| MESH:D007674 | Kidney Diseases | sodium arsenite | 14.43 | 20008137 | |
| MESH:D007680 | Kidney Neoplasms | 4,4'-diaminodiphenylmethane | 17.34 | 6582329 | |
| MESH:D007680 | Kidney Neoplasms | Cyclosporine | 17.34 | 12371664 | |
| MESH:D007680 | Kidney Neoplasms | Diethylstilbestrol | 17.34 | 16762066 15003126 14681315 | |
| MESH:D007680 | Kidney Neoplasms | Estradiol | 17.34 | 15610895 | |
| MESH:D007680 | Kidney Neoplasms | Tamoxifen | 17.34 | 18625569 | |
| MESH:D007859 | Learning Disorders | Diethylstilbestrol | 12.53 | 17184923 | |
| MESH:D007859 | Learning Disorders | Endosulfan | 12.53 | 8157075 | |
| MESH:D007859 | Learning Disorders | mangiferin | 12.53 | 19182383 | |
| MESH:D007889 | Leiomyoma | Curcumin | 9.04 | 18555241 | |
| MESH:D007889 | Leiomyoma | Raloxifene | 9.04 | 16973256 | |
| MESH:D016773 | Leishmaniasis, Cutaneous | Zinc Sulfate | 3.70 | 15237267 | |
| MESH:D007938 | Leukemia | Curcumin | 5.28 | 18462866 | |
| MESH:D007938 | Leukemia | Genistein | 5.28 | 17468513 18980019 | |
| MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | Curcumin | 3.59 | 16106398 | |
| MESH:D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | mangiferin | 4.09 | 15498116 | |
| MESH:D015458 | Leukemia, T-Cell | Curcumin | 4.11 | 16106398 | |
| MESH:D007970 | Leukopenia | Lipopolysaccharides | 4.01 | 15821434 | |
| MESH:D007984 | Leydig Cell Tumor | vinclozolin | 4.05 | 16417039 | |
| MESH:D008064 | Lipidoses | Tamoxifen | 2.65 | 17567588 15342952 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 8.56 | 21278145 17157831 17334410 16221502 17174718 16239168 11408273 16943688 11903743 | |
| MESH:D008103 | Liver Cirrhosis | Dietary Fats | 8.56 | 18296743 | |
| MESH:D008103 | Liver Cirrhosis | Phenobarbital | 8.56 | 21047994 | |
| MESH:D008105 | Liver Cirrhosis, Biliary | 4,4'-diaminodiphenylmethane | 2.73 | 15034207 9327722 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 15.33 | 17631135 12609069 16248980 14716496 15876570 12666154 11481614 18472332 17640975 15052691 12958196 16011737 15996030 18166357 18205269 18263696 17557913 17976157 16192424 18277467 12667390 14748882 15730626 18420326 14724832 18395095 16116963 17900296 13678700 16097048 18705752 15959796 15057751 16033810 15362042 18481824 12546737 14716833 18339082 17823541 18156304 18054572 15650968 15818738 18279442 17761835 17721639 17481882 10355542 17922224 15338365 17869086 15123356 17714472 12445421 18251166 12898905 14512876 17525996 15370692 18412020 18376398 12632512 16015684 15893842 12445418 18418968 12649538 17565644 16638106 20821823 17708605 12741479 15925388 18187930 15931870 12632514 18472094 18210741 14620537 15673190 18006644 17766677 12389079 18395914 17698563 16027843 16136751 18429990 18317297 17944888 12586293 17805973 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Curcumin | 15.33 | 18006644 18705752 17355460 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Dexamethasone | 15.33 | 16718785 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Estradiol | 15.33 | 14716833 14659978 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Genistein | 15.33 | 17823541 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Lipopolysaccharides | 15.33 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 15.33 | 15474484 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | rofecoxib | 15.33 | 17565644 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tamoxifen | 15.33 | 18564211 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tetrachlorodibenzodioxin | 15.33 | 12878042 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 9.96 | 16611625 19460945 12969438 12587719 11587558 19784758 16610002 19014921 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 9.96 | 17285989 16246199 15830285 15720792 16964402 | |
| MESH:D008107 | Liver Diseases | Curcumin | 9.96 | 16956363 | |
| MESH:D008107 | Liver Diseases | Phenobarbital | 9.96 | 19363144 | |
| MESH:D008107 | Liver Diseases | polyphenols | 9.96 | 16698588 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 3.49 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 7.41 | 16871587 17185352 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 7.41 | 14706259 16899240 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 20.28 | 20195826 21137059 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 20.28 | 19294768 | |
| MESH:D008113 | Liver Neoplasms | Diethylstilbestrol | 20.28 | 15890375 16712894 | |
| MESH:D008113 | Liver Neoplasms | Phenobarbital | 20.28 | 8742319 19812893 19073162 21047994 15975961 19482888 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 20.28 | 20007298 16377806 15890375 | |
| MESH:D008113 | Liver Neoplasms | sodium arsenite | 20.28 | 16712894 15276417 | |
| MESH:D008113 | Liver Neoplasms | Tamoxifen | 20.28 | 16684651 | |
| MESH:D008113 | Liver Neoplasms | Tetrachlorodibenzodioxin | 20.28 | 16984957 | |
| MESH:D008114 | Liver Neoplasms, Experimental | 4,4'-diaminodiphenylmethane | 13.74 | 3712494 598648 1399818 6587162 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 13.74 | 12014681 15583823 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Methylcholanthrene | 13.74 | 598648 1399818 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Phenobarbital | 13.74 | 6150874 1399818 2563599 17172636 18308698 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Tetrachlorodibenzodioxin | 13.74 | 12151625 | |
| MESH:D008171 | Lung Diseases | chromium hexavalent ion | 13.64 | 16775837 | |
| MESH:D008171 | Lung Diseases | Mustard Gas | 13.64 | 18161513 18702808 | |
| MESH:D008171 | Lung Diseases | Ozone | 13.64 | 8266340 19066396 | |
| MESH:D008171 | Lung Diseases | sodium arsenite | 13.64 | 19095001 | |
| MESH:D055370 | Lung Injury | Lipopolysaccharides | 7.03 | 21114838 | |
| MESH:D055370 | Lung Injury | Ozone | 7.03 | 20417186 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 19.79 | 18816296 20064080 20135361 20869020 6695378 17053015 20464547 18520028 18569708 | |
| MESH:D008175 | Lung Neoplasms | bexarotene | 19.79 | 17849452 | |
| MESH:D008175 | Lung Neoplasms | chromium hexavalent ion | 19.79 | 16876463 16570259 | |
| MESH:D008175 | Lung Neoplasms | Curcumin | 19.79 | 18462866 19359593 16243823 | |
| MESH:D008175 | Lung Neoplasms | Dexamethasone | 19.79 | 15824018 11195469 | |
| MESH:D008175 | Lung Neoplasms | mangiferin | 19.79 | 18520028 18816296 18569708 | |
| MESH:D008175 | Lung Neoplasms | Methylcholanthrene | 19.79 | 21163286 9230183 20512841 10545420 16271038 11893704 20970405 15390079 7750092 6695378 17909032 16337739 1399818 | |
| MESH:D008175 | Lung Neoplasms | Mustard Gas | 19.79 | 3148597 8781369 | |
| MESH:D008175 | Lung Neoplasms | Ozone | 19.79 | 8597069 7614698 | |
| MESH:D008175 | Lung Neoplasms | sodium arsenite | 19.79 | 16712894 15276417 19931552 17077188 17306315 | |
| MESH:D008175 | Lung Neoplasms | Tamoxifen | 19.79 | 18625569 | |
| MESH:D008175 | Lung Neoplasms | Tetrachlorodibenzodioxin | 19.79 | 19555203 11884234 | |
| MESH:D008181 | Lupus Nephritis | Diethylstilbestrol | 4.46 | 15166399 | |
| MESH:D008223 | Lymphoma | Curcumin | 6.08 | 18462866 | |
| MESH:D008223 | Lymphoma | Diethylstilbestrol | 6.08 | 15700306 | |
| MESH:D016399 | Lymphoma, T-Cell | Curcumin | 4.02 | 16173963 | |
| MESH:D016410 | Lymphoma, T-Cell, Cutaneous | bexarotene | 4.47 | 11161223 | |
| MESH:D008268 | Macular Degeneration | marker/mechanism | 17767156 | ||
| MESH:D008275 | Magnesium Deficiency | Magnesium | 5.76 | 17823441 | |
| MESH:D052801 | Male Urogenital Diseases | Diethylstilbestrol | 4.82 | 16002989 | |
| MESH:D015674 | Mammary Neoplasms, Animal | Tamoxifen | 3.08 | 19428831 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | bexarotene | 17.45 | 15591091 19196722 19196723 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Estradiol | 17.45 | 11408345 11807958 17203775 16891317 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Genistein | 17.45 | 14578162 12929590 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Ibuprofen | 17.45 | 10697514 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Progesterone | 17.45 | 11408345 17203775 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Tamoxifen | 17.45 | 19196723 14580682 16827153 11731420 19196722 | |
| MESH:D020149 | Manganese Poisoning | Estradiol | 10.33 | 19453300 | |
| MESH:D020149 | Manganese Poisoning | Tamoxifen | 10.33 | 19453300 | |
| MESH:D008545 | Melanoma | Curcumin | 4.17 | 18462866 17885582 | |
| MESH:D008545 | Melanoma | sodium arsenite | 4.17 | 16487513 19082730 | |
| MESH:D008545 | Melanoma | Tamoxifen | 4.17 | 12393984 19393235 | |
| MESH:D018328 | Melanoma, Amelanotic | Tamoxifen | 3.50 | 15990972 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 2.90 | 19513568 | |
| MESH:D008569 | Memory Disorders | Curcumin | 7.87 | 17263510 | |
| MESH:D008569 | Memory Disorders | mangiferin | 7.87 | 19182383 | |
| MESH:D008664 | Metal Metabolism, Inborn Errors | Cyclosporine | 4.09 | 16801185 | |
| MESH:D008679 | Metaplasia | Ozone | 4.41 | 10496685 | |
| MESH:D008881 | Migraine Disorders | Magnesium | 4.26 | 18803445 | |
| MESH:D019846 | Miller Fisher Syndrome | rEV576 protein, tick | 7.10 | 18844789 | |
| MESH:D018200 | Mixed Tumor, Mullerian | Raloxifene | 4.85 | 15863610 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 2.65 | 16381670 | |
| MESH:D009101 | Multiple Myeloma | Curcumin | 9.28 | 19372569 | |
| MESH:D009101 | Multiple Myeloma | Dexamethasone | 9.28 | 16118317 15867202 15744524 | |
| MESH:D009101 | Multiple Myeloma | Raloxifene | 9.28 | 16497877 | |
| MESH:D009102 | Multiple Organ Failure | Zymosan | 4.58 | 12879239 17724436 10890648 15259001 15241586 15213630 12130978 10479408 18160304 15834315 | |
| MESH:D009134 | Muscular Atrophy, Spinal | Curcumin | 4.23 | 17962980 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 2.84 | 16239165 | |
| MESH:D020720 | Myasthenia Gravis, Autoimmune, Experimental | rEV576 protein, tick | 7.10 | 19194881 17215252 | |
| MESH:D009190 | Myelodysplastic Syndromes | Dexamethasone | 3.11 | 9809623 | |
| MESH:D009203 | Myocardial Infarction | Genistein | 7.61 | 17141266 | |
| MESH:D009203 | Myocardial Infarction | mangiferin | 7.61 | 19172585 17052832 16584858 16538859 16697266 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 7.61 | 19151258 | |
| MESH:D017202 | Myocardial Ischemia | Tetrachlorodibenzodioxin | 2.46 | 12213967 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Estradiol | 11.02 | 16810080 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Genistein | 11.02 | 17141266 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 11.02 | 16411023 | |
| MESH:D020191 | Myoclonic Epilepsies, Progressive | Phenobarbital | 3.79 | 17484760 | |
| MESH:D009232 | Myxoma | Raloxifene | 4.85 | 16343187 | |
| MESH:D009361 | Neoplasm Invasiveness | Curcumin | 3.72 | 18495463 | |
| MESH:D009362 | Neoplasm Metastasis | 4,4'-diaminodiphenylmethane | 4.59 | 3581430 | |
| MESH:D009362 | Neoplasm Metastasis | Tamoxifen | 4.59 | 19393235 | |
| MESH:D009364 | Neoplasm Recurrence, Local | Tamoxifen | 2.24 | 19410462 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 8.65 | 11141357 | |
| MESH:D009369 | Neoplasms | Diethylstilbestrol | 8.65 | 15313581 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 8.65 | 17405874 | |
| MESH:D009369 | Neoplasms | sodium arsenite | 8.65 | 11559025 | |
| MESH:D009374 | Neoplasms, Experimental | sodium arsenite | 3.01 | 20056578 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | bexarotene | 14.29 | 19196722 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | Curcumin | 14.29 | 12497104 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | Tamoxifen | 14.29 | 19189210 19196722 19200415 | |
| MESH:D009389 | Neovascularization, Pathologic | Estradiol | 3.05 | 17289903 | |
| MESH:D009395 | Nephritis, Interstitial | Ibuprofen | 4.29 | 6375363 | |
| MESH:D009402 | Nephrosis, Lipoid | Cyclosporine | 3.74 | 17954296 | |
| MESH:D009404 | Nephrotic Syndrome | Cyclosporine | 2.70 | 19348381 18481113 | |
| MESH:D009410 | Nerve Degeneration | Ibuprofen | 7.35 | 10961664 | |
| MESH:D009410 | Nerve Degeneration | mangiferin | 7.35 | 17433543 | |
| MESH:D009421 | Nervous System Malformations | bisphenol A | 23.88 | 11399458 16427766 | |
| MESH:D009421 | Nervous System Malformations | Diethylstilbestrol | 23.88 | 11399458 | |
| MESH:D009421 | Nervous System Malformations | Estradiol | 23.88 | 16427766 11399458 | |
| MESH:D009421 | Nervous System Malformations | Genistein | 23.88 | 16427766 | |
| MESH:D009421 | Nervous System Malformations | Tetrachlorodibenzodioxin | 23.88 | 14600291 | |
| MESH:D009423 | Nervous System Neoplasms | Curcumin | 4.93 | 18462866 | |
| MESH:D009436 | Neural Tube Defects | 4,4'-diaminodiphenylmethane | 5.66 | 6679447 | |
| MESH:D009436 | Neural Tube Defects | sodium arsenite | 5.66 | 12854658 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 2.31 | 18514411 | |
| MESH:D009503 | Neutropenia | Mustard Gas | 3.34 | 16761898 7688884 | |
| MESH:D009669 | Nose Neoplasms | chromium hexavalent ion | 4.44 | 16876463 | |
| MESH:D009765 | Obesity | Curcumin | 6.08 | 19297423 | |
| MESH:D009765 | Obesity | Dietary Fats | 6.08 | 21332399 20132043 20518802 19632207 16723640 18674790 17217161 18457598 11836018 | |
| MESH:D009765 | Obesity | pirinixic acid | 6.08 | 20558911 | |
| MESH:D009784 | Occupational Diseases | 4,4'-diaminodiphenylmethane | 2.82 | 6482804 4026338 | |
| MESH:D009902 | Optic Neuritis | 4,4'-diaminodiphenylmethane | 4.32 | 3988306 | |
| MESH:D010003 | Osteoarthritis | Ibuprofen | 6.79 | 7009135 | |
| MESH:D010003 | Osteoarthritis | rofecoxib | 6.79 | 16690336 | |
| MESH:D010018 | Osteomalacia | Phenobarbital | 3.68 | 17016548 | |
| MESH:D010024 | Osteoporosis | Curcumin | 13.22 | 18719352 | |
| MESH:D010024 | Osteoporosis | Genistein | 13.22 | 19401787 | |
| MESH:D010024 | Osteoporosis | Levonorgestrel | 13.22 | 12665316 | |
| MESH:D010024 | Osteoporosis | Raloxifene | 13.22 | 19059307 17882678 15775268 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Genistein | 8.03 | 16169203 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Raloxifene | 8.03 | 15579764 17823083 15758505 17893378 | |
| MESH:D010049 | Ovarian Diseases | bisphenol A | 4.30 | 11985600 | |
| MESH:D010051 | Ovarian Neoplasms | Curcumin | 18.66 | 18462866 19020741 | |
| MESH:D010051 | Ovarian Neoplasms | Estradiol | 18.66 | 19401270 | |
| MESH:D010051 | Ovarian Neoplasms | Genistein | 18.66 | 19005980 | |
| MESH:D010051 | Ovarian Neoplasms | Medroxyprogesterone Acetate | 18.66 | 17393432 | |
| MESH:D010051 | Ovarian Neoplasms | Mifepristone | 18.66 | 16525653 | |
| MESH:D010051 | Ovarian Neoplasms | Progesterone | 18.66 | 17393432 16525653 | |
| MESH:D010051 | Ovarian Neoplasms | sodium arsenite | 18.66 | 17306315 15276417 | |
| MESH:D010146 | Pain | Acetaminophen | 5.12 | 16870215 | |
| MESH:D010146 | Pain | Ibuprofen | 5.12 | 3291741 | |
| MESH:D010149 | Pain, Postoperative | Ibuprofen | 9.42 | 16678543 | |
| MESH:D010149 | Pain, Postoperative | rofecoxib | 9.42 | 18165598 16678543 | |
| MESH:D010190 | Pancreatic Neoplasms | Curcumin | 7.03 | 19196508 19401701 17440100 | |
| MESH:D010190 | Pancreatic Neoplasms | Ibuprofen | 7.03 | 12384795 | |
| MESH:D010190 | Pancreatic Neoplasms | Phenobarbital | 7.03 | 16965848 | |
| MESH:D010195 | Pancreatitis | Trinitrobenzenesulfonic Acid | 3.58 | 17698068 | |
| MESH:D016584 | Panic Disorder | Ethinyl Estradiol | 3.05 | 11578682 | |
| MESH:D010212 | Papilloma | 4,4'-diaminodiphenylmethane | 2.82 | 7296757 | |
| MESH:D010300 | Parkinson Disease | mangiferin | 3.42 | 17433543 | |
| MESH:D010382 | Peliosis Hepatis | Tetrachlorodibenzodioxin | 3.55 | 12520081 | |
| MESH:D010518 | Periodontitis | mangiferin | 4.91 | 19026997 | |
| MESH:D010538 | Peritonitis | Ozone | 8.20 | 16369182 | |
| MESH:D010538 | Peritonitis | Zymosan | 8.20 | 15979727 15259001 18977430 14761945 19641140 18760300 17826846 11985352 18557954 19088179 17371808 | |
| MESH:D010787 | Photosensitivity Disorders | 4,4'-diaminodiphenylmethane | 3.77 | 6228378 | |
| MESH:D010900 | Pituitary Diseases | Diethylstilbestrol | 4.47 | 14722030 | |
| MESH:D010911 | Pituitary Neoplasms | Diethylstilbestrol | 4.00 | 15687265 16977796 | |
| MESH:D011014 | Pneumonia | Lipopolysaccharides | 8.83 | 12224865 11605937 | |
| MESH:D011014 | Pneumonia | Ozone | 8.83 | 18381685 18007984 18929643 | |
| MESH:D011041 | Poisoning | Mustard Gas | 3.17 | 15727166 | |
| MESH:D011085 | Polycystic Ovary Syndrome | Flutamide | 4.39 | 15356085 | |
| MESH:D017119 | Porphyria Cutanea Tarda | Tetrachlorodibenzodioxin | 2.91 | 18163543 | |
| MESH:D011230 | Precancerous Conditions | Cyclosporine | 7.02 | 12371664 | |
| MESH:D011230 | Precancerous Conditions | Phenobarbital | 7.02 | 2563599 | |
| MESH:D054198 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Dexamethasone | 3.12 | 21297632 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | bisphenol A | 17.67 | 10548101 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Diethylstilbestrol | 17.67 | 17184923 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Tetrachlorodibenzodioxin | 17.67 | 11896295 11118676 11222880 11399792 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | vinclozolin | 17.67 | 18042343 18220299 19015723 | |
| MESH:D011469 | Prostatic Diseases | vinclozolin | 4.25 | 18220299 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | bisphenol A | 8.49 | 20887781 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | Estradiol | 8.49 | 20887781 | |
| MESH:D011471 | Prostatic Neoplasms | Androgens | 5.09 | 15389811 17909013 16998812 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 5.09 | 17292933 | |
| MESH:D011471 | Prostatic Neoplasms | bisphenol A | 5.09 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Cholecalciferol | 5.09 | 17024972 | |
| MESH:D011471 | Prostatic Neoplasms | Curcumin | 5.09 | 11398177 10851300 12497104 15129424 18156803 18226269 18769126 | |
| MESH:D011471 | Prostatic Neoplasms | Diethylstilbestrol | 5.09 | 15846301 17136230 15046698 | |
| MESH:D011471 | Prostatic Neoplasms | Estradiol | 5.09 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Flutamide | 5.09 | 3169114 | |
| MESH:D011471 | Prostatic Neoplasms | Genistein | 5.09 | 15256057 15378649 16925846 | |
| MESH:D011471 | Prostatic Neoplasms | Ibuprofen | 5.09 | 17409433 | |
| MESH:D011471 | Prostatic Neoplasms | Raloxifene | 5.09 | 16220300 16536755 15731164 | |
| MESH:D011471 | Prostatic Neoplasms | sodium arsenite | 5.09 | 16039940 | |
| MESH:D011471 | Prostatic Neoplasms | Tamoxifen | 5.09 | 15067354 | |
| MESH:D011472 | Prostatitis | vinclozolin | 4.25 | 18629315 | |
| MESH:D011507 | Proteinuria | Ibuprofen | 4.00 | 6375363 | |
| MESH:D011537 | Pruritus | Ethinyl Estradiol | 12.38 | 15861022 16919318 | |
| MESH:D011537 | Pruritus | Levonorgestrel | 12.38 | 15861022 | |
| MESH:D011537 | Pruritus | Mustard Gas | 12.38 | 18058305 | |
| MESH:D019310 | Pseudolymphoma | Phenobarbital | 3.80 | 12752131 | |
| MESH:D011565 | Psoriasis | Cyclosporine | 1.94 | 16882103 | |
| MESH:D011629 | Puberty, Precocious | bisphenol A | 4.10 | 10548101 | |
| MESH:D011656 | Pulmonary Emphysema | Curcumin | 3.92 | 19168576 | |
| MESH:D011658 | Pulmonary Fibrosis | Mustard Gas | 2.62 | 17266442 17620002 17894541 17720292 10334151 | |
| MESH:D011693 | Purpura | Raloxifene | 4.85 | 15770314 | |
| MESH:D011833 | Radiation Injuries, Experimental | mangiferin | 5.71 | 15830843 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.01 | 19058328 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Curcumin | 7.21 | 18379247 10666014 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Dexamethasone | 7.21 | 18379247 11700416 | |
| MESH:D012130 | Respiratory Hypersensitivity | Lipopolysaccharides | 7.17 | 10835634 | |
| MESH:D012130 | Respiratory Hypersensitivity | trimellitic anhydride | 7.17 | 20219652 | |
| MESH:D015619 | Respiratory System Abnormalities | Tetrachlorodibenzodioxin | 3.18 | 18990726 | |
| MESH:D012162 | Retinal Degeneration | 4,4'-diaminodiphenylmethane | 2.84 | 3692021 | |
| MESH:D012468 | Salivary Gland Neoplasms | Progesterone | 2.56 | 18045962 | |
| MESH:D012509 | Sarcoma | Curcumin | 3.52 | 18462866 | |
| MESH:D012640 | Seizures | Endosulfan | 4.88 | 10698677 7539098 | |
| MESH:D012640 | Seizures | Phenobarbital | 4.88 | 11442880 16876388 3137016 4039156 | |
| MESH:D003294 | Seizures, Febrile | Phenobarbital | 4.13 | 6407741 | |
| MESH:D018805 | Sepsis | Curcumin | 7.78 | 18389075 | |
| MESH:D018805 | Sepsis | Zymosan | 7.78 | 11441115 | |
| MESH:D012772 | Shock, Septic | mangiferin | 4.56 | 15177305 | |
| MESH:D012871 | Skin Diseases | Mustard Gas | 2.50 | 12880345 16961503 15451306 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 7.21 | 19755658 10029692 | |
| MESH:D012878 | Skin Neoplasms | sodium arsenite | 7.21 | 18572023 19524636 | |
| MESH:D012878 | Skin Neoplasms | Tetrachlorodibenzodioxin | 7.21 | 16192470 | |
| MESH:D013088 | Spermatocele | Diethylstilbestrol | 16.10 | 16709447 16002989 | |
| MESH:D013088 | Spermatocele | Ethinyl Estradiol | 16.10 | 16709447 | |
| MESH:D013088 | Spermatocele | Tamoxifen | 16.10 | 16709447 | |
| MESH:D013119 | Spinal Cord Injuries | Progesterone | 8.60 | 16503802 15862959 | |
| MESH:D013119 | Spinal Cord Injuries | Tamoxifen | 8.60 | 19457130 | |
| MESH:D016135 | Spinal Dysraphism | sodium arsenite | 3.25 | 12854658 | |
| MESH:D013272 | Stomach Diseases | Dexamethasone | 3.64 | 15472012 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 1.56 | 2093021 20155912 | |
| MESH:D013276 | Stomach Ulcer | Curcumin | 8.77 | 16631530 19188055 | |
| MESH:D013276 | Stomach Ulcer | Dexamethasone | 8.77 | 15138204 | |
| MESH:D013276 | Stomach Ulcer | mangiferin | 8.77 | 17918041 | |
| MESH:D020521 | Stroke | Raloxifene | 3.27 | 16837676 | |
| MESH:D019966 | Substance-Related Disorders | bisphenol A | 3.31 | 16045194 16684133 | |
| MESH:D013705 | Temporomandibular Joint Disorders | polyphenols | 4.55 | 17997062 | |
| MESH:D013921 | Thrombocytopenia | Lipopolysaccharides | 3.56 | 15821434 | |
| MESH:D019851 | Thrombophilia | Ethinyl Estradiol | 2.98 | 11994571 | |
| MESH:D013927 | Thrombosis | Ethinyl Estradiol | 2.57 | 15669648 | |
| MESH:D013959 | Thyroid Diseases | Tetrachlorodibenzodioxin | 3.20 | 12697716 | |
| MESH:D013964 | Thyroid Neoplasms | 4,4'-diaminodiphenylmethane | 5.37 | 1399818 6582329 3712494 7505956 6587162 | |
| MESH:D013964 | Thyroid Neoplasms | Phenobarbital | 5.37 | 1399818 | |
| MESH:D013978 | Tibial Fractures | Estradiol | 11.39 | 19048282 | |
| MESH:D013978 | Tibial Fractures | Raloxifene | 11.39 | 19048282 | |
| MESH:D014235 | Trichinellosis | mangiferin | 5.36 | 14669257 | |
| MESH:D001749 | Urinary Bladder Neoplasms | 4,4'-diaminodiphenylmethane | 19.09 | 8074119 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 19.09 | 17053015 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Curcumin | 19.09 | 18593936 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Diethylstilbestrol | 19.09 | 17306315 16712894 16452187 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Raloxifene | 19.09 | 17572228 | |
| MESH:D001749 | Urinary Bladder Neoplasms | sodium arsenite | 19.09 | 16712894 16452187 17306315 11723127 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Tamoxifen | 19.09 | 16712894 17572228 8653321 | |
| MESH:D014565 | Urogenital Neoplasms | Curcumin | 4.58 | 18462866 | |
| MESH:D014581 | Urticaria | Acetaminophen | 2.35 | 10982225 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Diethylstilbestrol | 7.54 | 16175088 | |
| MESH:D002583 | Uterine Cervical Neoplasms | sodium arsenite | 7.54 | 11813266 | |
| MESH:D014591 | Uterine Diseases | bisphenol A | 11.49 | 14652134 | |
| MESH:D014591 | Uterine Diseases | Diethylstilbestrol | 11.49 | 14652134 | |
| MESH:D014594 | Uterine Neoplasms | Diethylstilbestrol | 7.31 | 16690809 15809267 | |
| MESH:D014594 | Uterine Neoplasms | Ethinyl Estradiol | 7.31 | 14692618 | |
| MESH:D014605 | Uveitis | Cyclosporine | 16.27 | 1336536 | |
| MESH:D014605 | Uveitis | Dexamethasone | 16.27 | 1336536 | |
| MESH:D014605 | Uveitis | Zymosan | 16.27 | 11006244 | |
| MESH:D014625 | Vaginal Neoplasms | Diethylstilbestrol | 3.77 | 16513791 16002989 | |
| MESH:D014652 | Vascular Diseases | sodium arsenite | 3.74 | 17056641 | |
| MESH:D054079 | Vascular Malformations | Tetrachlorodibenzodioxin | 3.89 | 12125929 | |
| MESH:D020301 | Vasospasm, Intracranial | Ibuprofen | 4.51 | 19057314 | |
| MESH:D054556 | Venous Thromboembolism | Raloxifene | 4.51 | 16837676 | |
| MESH:D020246 | Venous Thrombosis | Ethinyl Estradiol | 8.72 | 14671159 15869587 | |
| MESH:D020246 | Venous Thrombosis | Levonorgestrel | 8.72 | 15869587 | |
| MESH:D014846 | Vulvar Neoplasms | Raloxifene | 4.85 | 16343187 | |
| MESH:D019282 | Wasting Syndrome | Tetrachlorodibenzodioxin | 3.55 | 15886252 | |
| MESH:D015430 | Weight Gain | Dietary Fats | 3.15 | 16723640 | |
| MESH:D014985 | Xerophthalmia | Cyclosporine | 3.74 | 17120751 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:05142 | Chagas disease (American trypanosomiasis) |
| KEGG:04610 | Complement and coagulation cascades |
| KEGG:05140 | Leishmaniasis |
| KEGG:04145 | Phagosome |
| REACT:14797 | Signaling by GPCR |
| REACT:6900 | Signaling in Immune system |
| KEGG:05150 | Staphylococcus aureus infection |
| KEGG:05322 | Systemic lupus erythematosus |
| KEGG:05152 | Tuberculosis |
| Releated gene ID | Related gene Name |
|---|---|
| PA25897 | C3 |
| Releated disease ID | Related disease Name |
|---|---|
| PA134850558 | Macular Degeneration |
| Releated drug ID | Related drug Name |
|---|---|
| PA450287 | magnesium |
| PA449750 | gemfibrozil |