AutismKB 2.0

Annotation Detail for TRAF2


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Basic Information Top
Gene Symbol:TRAF2 ( MGC:45012,TRAP,TRAP3 )
Gene Full Name: TNF receptor-associated factor 2
Band: 9q34.3
Quick LinksEntrez ID:7186; OMIM: 601895; Uniprot ID:TRAF2_HUMAN; ENSEMBL ID: ENSG00000127191; HGNC ID: 12032
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04920Adipocytokine signaling pathway
hsa05160Hepatitis C
hsa04010MAPK signaling pathway
hsa04141Protein processing in endoplasmic reticulum
hsa04622RIG-I-like receptor signaling pathway
hsa05222Small cell lung cancer
hsa04210Apoptosis
hsa05200Pathways in cancer
Pathway IDPathway Name
Apoptosis
Pathway IDPathway Name
200031CD40/CD40L signaling
200133HIV-1 Nef: Negative effector of Fas and TNF-alpha
200014p38 MAPK signaling pathway
200086TNF receptor signaling pathway
200148Caspase cascade in apoptosis
200100Ceramide signaling pathway
200056TRAIL signaling pathway
Pathway IDPathway Name
P00006Apoptosis signaling pathway
P00059p53 pathway
Pathway IDPathway Name
500256TNF signaling
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C047948 1'-acetoxychavicol acetate 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of TRAF2 protein]decreases reaction|increases expression 15905586
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of TRAF2 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of TRAF2 mRNAaffects expression 17562736
D001151 Arsenic [Arsenic co-treated with Fluorides] results in decreased expression of TRAF2 mRNAaffects cotreatment|decreases expression 19962721
C006632 arsenic trioxide arsenic trioxide results in decreased expression of TRAF2 mRNAdecreases expression 17530438
C006632 arsenic trioxide arsenic trioxide results in increased expression of TRAF2 mRNAincreases expression 19730151
D001761 Bleomycin Bleomycin results in decreased expression of TRAF2 proteindecreases expression 15371238
D002251 Carbon Tetrachloride [Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in decreased expression of TRAF2 mRNAaffects cotreatment|decreases expression 16610055
D003042 Cocaine Cocaine affects the expression of TRAF2 mRNAaffects expression 15681117
D003078 Colchicine TRAF2 protein affects the susceptibility to Colchicineaffects response to substance 20159942
D003474 Curcumin Curcumin results in increased expression of TRAF2 mRNAincreases expression 16101141
D003840 Deoxycholic Acid TRAF2 protein results in decreased susceptibility to Deoxycholic Aciddecreases response to substance 12507930
D002945 Cisplatin TRAF2 protein affects the susceptibility to Cisplatinaffects response to substance 20159942
D001728 Dicumarol Dicumarol inhibits the reaction [TRAF2 protein results in increased activity of MAPK10 protein]decreases reaction|increases activity 10531305
D004642 Emodin Emodin results in increased expression of TRAF2 mRNAincreases expression 16045814
D004958 Estradiol Estradiol results in decreased expression of TRAF2 mRNAdecreases expression 18709148
D000431 Ethanol [Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in decreased expression of TRAF2 mRNAaffects cotreatment|decreases expression 16610055
D005047 Etoposide TRAF2 protein affects the susceptibility to Etoposideaffects response to substance 20159942
D005459 Fluorides [Arsenic co-treated with Fluorides] results in decreased expression of TRAF2 mRNAaffects cotreatment|decreases expression 19962721
D005459 Fluorides Fluorides results in decreased expression of TRAF2 mRNAdecreases expression 19962721
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of TRAF2 mRNAaffects cotreatment|increases expression 17183730
D006861 Hydrogen Peroxide TRAF2 protein affects the susceptibility to Hydrogen Peroxideaffects response to substance 20159942
D007213 Indomethacin Indomethacin results in decreased expression of TRAF2 proteindecreases expression 18799549
D007530 Isoflurane Isoflurane results in decreased expression of TRAF2 mRNAdecreases expression 16978161
D017239 Paclitaxel TRAF2 protein affects the susceptibility to Paclitaxelaffects response to substance 20159942
C002669 parthenolide parthenolide inhibits the reaction [FGF2 protein results in increased expression of TRAF2 mRNA]decreases reaction|increases expression 16921510
C002669 parthenolide parthenolide results in decreased expression of TRAF2 mRNAdecreases expression 16921510
C002669 parthenolide parthenolide results in decreased expression of TRAF2 proteindecreases expression 16921510
D010424 Pentobarbital Pentobarbital results in decreased expression of TRAF2 mRNAdecreases expression 16978161
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased expression of TRAF2 mRNAdecreases expression 18709148
C031280 pyrazole [Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in decreased expression of TRAF2 mRNAaffects cotreatment|decreases expression 16610055
C059514 resveratrol resveratrol results in decreased expression of TRAF2 proteindecreases expression 17164350
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of TRAF2 mRNAincreases expression 14718646
12167310
D019284 Thapsigargin Thapsigargin results in decreased expression of TRAF2 proteindecreases expression 18799549
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of TRAF2 mRNAaffects cotreatment|increases expression 17183730
C403304 zerumbone zerumbone inhibits the reaction [TRAF2 protein results in increased activity of [NFKB1 protein binds to RELA protein]]affects binding|decreases reaction|increases activity 16007145
C088658 zoledronic acid zoledronic acid results in increased expression of TRAF2 mRNAincreases expression 19036117
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 12.3817676605 18926900
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 12.3814514962 15322242 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 12.388875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.6419490988
MESH:D000138 Acidosis Ethanol 4.1711192467
MESH:D058186 Acute Kidney Injury Cisplatin 12.9217670903 12690470 15814532
MESH:D058186 Acute Kidney Injury resveratrol 12.9216538975
MESH:D058186 Acute Kidney Injury zoledronic acid 12.9219715164
MESH:D055371 Acute Lung Injury Bleomycin 4.5917118201
MESH:D000210 Acute-Phase Reaction zoledronic acid 5.1620200999
MESH:D000230 Adenocarcinoma arsenic trioxide 9.4911798837 19825857
MESH:D000230 Adenocarcinoma Cisplatin 9.4911798837 17638652
MESH:D000230 Adenocarcinoma Estradiol 9.4911473722
MESH:D000230 Adenocarcinoma Indomethacin 9.4916537180
MESH:D000236 Adenoma Indomethacin 6.4611497255
MESH:D000236 Adenoma resveratrol 6.4615688382
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.0516835633
MESH:D018246 Adrenocortical Adenoma Arsenic 4.8817306315
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.9915451039 15451040
MESH:D019973 Alcohol-Related Disorders Curcumin 4.7517887948
MESH:D016301 Alveolar Bone Loss Indomethacin 5.0417225004
MESH:D000544 Alzheimer Disease Curcumin 6.2815590663
MESH:D000544 Alzheimer Disease Indomethacin 6.2815579461 17627676
MESH:D000544 Alzheimer Disease resveratrol 6.2816183991 16162502
MESH:D000550 Amblyopia Valproic Acid 4.9017688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6711748828
MESH:D000799 Angioedema Acetaminophen 3.5110982225
MESH:D000853 Anophthalmos Ethanol 4.5015513904
MESH:D000860 Anoxia Bleomycin 5.0815782499
MESH:D001008 Anxiety Disorders Ethanol 13.5311141031
MESH:D001008 Anxiety Disorders Pentobarbital 13.5311141031 18313124
MESH:D001008 Anxiety Disorders Valproic Acid 13.5317497229
MESH:D001014 Aortic Aneurysm Indomethacin 4.5410231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.5510388637
MESH:D020261 Arsenic Poisoning Arsenic 2.7718414634 12569548 16251483 16835338
MESH:D018771 Arthralgia Indomethacin 4.842160914
MESH:D001169 Arthritis, Experimental resveratrol 3.3017115116
MESH:D001172 Arthritis, Rheumatoid Curcumin 4.6616807698
MESH:D001172 Arthritis, Rheumatoid Indomethacin 4.6611248219
MESH:D050197 Atherosclerosis Arsenic 9.9719371607 12928151
MESH:D050197 Atherosclerosis Curcumin 9.9718704882
MESH:D050197 Atherosclerosis resveratrol 9.9717967414 16873680
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8518985861 18396377 18316065 18775368 18558336 20603192 17157402 19232924 17507914 18940202 15238991 16609825 17688650 19460635 18177632
MESH:D001327 Autoimmune Diseases Curcumin 4.1719761891
MESH:D001477 Bartter Syndrome Indomethacin 4.6610684365
MESH:D001528 Behcet Syndrome Colchicine 5.7915870978
MESH:D001714 Bipolar Disorder Valproic Acid 2.9117594078 20046352
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.0016206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.0012125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.3315746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.338888407
MESH:D019046 Bone Marrow Neoplasms Cisplatin 11.1214601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 11.1214601052
MESH:D001859 Bone Neoplasms Paclitaxel 9.8415867366
MESH:D001859 Bone Neoplasms zoledronic acid 9.8417312309 15867366 16778634 16121404 19442620 11697798
MESH:D001862 Bone Resorption zoledronic acid 4.4111869084 18496637 16769263 8053405 15845617 18404659
MESH:D001929 Brain Edema Indomethacin 4.6911481608
MESH:D002545 Brain Ischemia Curcumin 15.2216770732
MESH:D002545 Brain Ischemia Indomethacin 15.2212524144
MESH:D002545 Brain Ischemia resveratrol 15.2217600658
MESH:D001932 Brain Neoplasms Curcumin 3.6617596214
MESH:D001943 Breast Neoplasms Cisplatin 6.6319526202 18382427
MESH:D001943 Breast Neoplasms Curcumin 6.6316243823 18462866 18593918 19250217
MESH:D001943 Breast Neoplasms Estradiol 6.6314630087 12948864 17289903 17261762 16675129 17018787 19861407 18497071
MESH:D001943 Breast Neoplasms Etoposide 6.6316322251
MESH:D001943 Breast Neoplasms Indomethacin 6.6317401462
MESH:D001943 Breast Neoplasms Paclitaxel 6.6315136595 16115903 16273361 18223236 16244791 18234424 18323546 11325840
MESH:D001943 Breast Neoplasms parthenolide 6.6316873071
MESH:D001943 Breast Neoplasms resveratrol 6.6317534123 17651959 16393696
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 6.6320435547
MESH:D001943 Breast Neoplasms zoledronic acid 6.6318695136 16096432
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.0311589617
MESH:D002056 Burns Ethanol 10.3216374292
MESH:D002056 Burns Indomethacin 10.3210459503
MESH:D002100 Cachexia Indomethacin 4.6815625704 16537180 15141370 11239499
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1416111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4616050911 16011737 3786805 15700767 10355542 18705752 16192424 16227642 16097048 15673190 15721981 16124888
MESH:D002277 Carcinoma Curcumin 7.4418593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.4416835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.4115504454 17687452
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 24.7816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 24.783084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 24.7816507464 17306315
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 24.7816217749 11135700 15073043 15553829 14691202
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 24.7818788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 24.7817982673
MESH:D006528 Carcinoma, Hepatocellular Estradiol 24.7816924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 24.7815289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 24.7816391822
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 24.7816313753
MESH:D006528 Carcinoma, Hepatocellular resveratrol 24.7816227395 19321006
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 10.3411053908
MESH:D018827 Carcinoma, Lewis Lung resveratrol 10.3416675471
MESH:D018276 Carcinoma, Medullary Indomethacin 5.0211352223 18791128 14736730
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 8.4516685392 12023789
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 8.4518414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 8.4519233551
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.5419014326
MESH:D002292 Carcinoma, Renal Cell Indomethacin 6.5417341418
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 6.5418507039
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8412490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 16.7718922899 17687452 15504454
MESH:D002294 Carcinoma, Squamous Cell Bleomycin 16.776189445
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 16.7717066447 6189445 18337622
MESH:D002294 Carcinoma, Squamous Cell Curcumin 16.7718462866
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 16.7715482327 12636206
MESH:D002294 Carcinoma, Squamous Cell resveratrol 16.7716227395
MESH:D002295 Carcinoma, Transitional Cell Arsenic 3.8018640142
MESH:D006332 Cardiomegaly Ethanol 6.2419332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.2418670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Arsenic 10.9819152805 17938729 15738583
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 10.9816936243
MESH:D002318 Cardiovascular Diseases resveratrol 10.9815458977
MESH:D002340 Carotid Artery Diseases Arsenic 4.0416973168 18022660
MESH:D002386 Cataract Acetaminophen 2.3910977129
MESH:D002471 Cell Transformation, Neoplastic Estradiol 2.5518566989
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.5920734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8916835633
MESH:D002764 Cholecystitis Indomethacin 4.8411181007
MESH:D002971 Cleft Lip Ethanol 3.4115513904
MESH:D002972 Cleft Palate Ethanol 5.4815513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.4816354765 15668235 12621046 8697196 15340226
MESH:D019970 Cocaine-Related Disorders Cocaine 5.3919606084
MESH:D003092 Colitis Curcumin 8.7416804969 18200517 16782535
MESH:D003092 Colitis resveratrol 8.7416474422
MESH:D003103 Coloboma Curcumin 4.2618809619
MESH:D003110 Colonic Neoplasms Curcumin 7.8619359593 16340194
MESH:D003110 Colonic Neoplasms Deoxycholic Acid 7.8616213893
MESH:D003110 Colonic Neoplasms Indomethacin 7.8615637740 15963497 11260862 15625704 15786552 15936596
MESH:D003110 Colonic Neoplasms resveratrol 7.8616338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 6.1220501625
MESH:D015179 Colorectal Neoplasms Cisplatin 6.1215273666
MESH:D015179 Colorectal Neoplasms Indomethacin 6.1212606626 17054584 11197048 18059344
MESH:D015179 Colorectal Neoplasms Paclitaxel 6.1218802399
MESH:D015179 Colorectal Neoplasms resveratrol 6.1216550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7917141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.5818497527
MESH:D003327 Coronary Disease resveratrol 3.5416507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8812609071
MESH:D018352 Coronavirus Infections Indomethacin 5.3917302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 5.0910525206
MESH:D019465 Craniofacial Abnormalities Ethanol 5.0915451040 19302082 15513904 15451039 10194807 11873399 11198716
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.0915322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Valproic Acid 5.0916575769 8888407 17688650
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.7018551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.8015213294
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.5116873680
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 4.1218403477
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1217107852
MESH:D003928 Diabetic Nephropathies Curcumin 13.5218204486
MESH:D003928 Diabetic Nephropathies Estradiol 13.5219279558
MESH:D003928 Diabetic Nephropathies resveratrol 13.5216286809
MESH:D003967 Diarrhea Indomethacin 3.497907874 7237001
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 17.0721346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 17.0719420014 18071297 14725611 18713872 17522070 12153990 16781746 11739529 11421492 14550746 19923254 11529661 2444490 10915739 12392966 11287661 12705907 12540782 19085960 10663392 15968718 11743745 19416960 17906064 16081117 14986274 12594235 11461765 16393943 15619225 19164858 12958197 19370779 16109766 19739265 11834606 16227642 10774834 16177239 16485898 17562736
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 17.076623471 7179309 15998439 9327722 3732212 6884620 19336974 16177239 3786805 4309450 7120509 2869522 7440962 21278145 11566570 19085960 16227642 15968718 17522070 15027814 10915739 10092053
MESH:D056486 Drug-Induced Liver Injury Ethanol 17.0711566570
MESH:D056486 Drug-Induced Liver Injury pyrazole 17.0712499123
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 17.0720420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 17.0719641884 1733752
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7719426721
MESH:D004362 Drug Toxicity Cisplatin 7.3815033597 19839026 12649298 12231392
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.3811462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.8218446180 18043480 16133044 16326151 12774134 17190690
MESH:D004381 Duodenal Ulcer Curcumin 8.3917351913
MESH:D004381 Duodenal Ulcer Indomethacin 8.3917329845 17045617 11535926 17202747 17151854 17351913 11595415 11595431 11991626 10671773 16699067
MESH:D004421 Dystonia Valproic Acid 3.751851702
MESH:D004487 Edema Bleomycin 18.6317118201
MESH:D004487 Edema Indomethacin 18.6316100529 8985016 7907874 7990266 19703484 10653021 8273558
MESH:D004487 Edema perfluorooctanoic acid 18.6317259670 12083418
MESH:D004487 Edema resveratrol 18.638985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 18.6311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.5716714409 18230668 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 3.7217872969
MESH:D016889 Endometrial Neoplasms Estradiol 2.7718566989 19148513 11473722
MESH:D004715 Endometriosis Indomethacin 8.1415652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.149294722 10568697
MESH:D019446 Endotoxemia Indomethacin 4.1818509659
MESH:D004751 Enteritis Indomethacin 4.4216328016 10567023 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 11.3117980183
MESH:D020345 Enterocolitis, Necrotizing resveratrol 11.3117923197
MESH:D004802 Eosinophilia Indomethacin 3.7411298111
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.8417275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 3.593922381 16628512
MESH:D004827 Epilepsy Valproic Acid 2.7720417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.326426943 7562514 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 3.987750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.743659116
MESH:D004938 Esophageal Neoplasms arsenic trioxide 12.8912903497
MESH:D004938 Esophageal Neoplasms Cisplatin 12.8917638652 16785472 16481741 15173087 15464296
MESH:D004938 Esophageal Neoplasms Ethanol 12.8916704527
MESH:D004938 Esophageal Neoplasms Indomethacin 12.8911005569
MESH:D004938 Esophageal Neoplasms Paclitaxel 12.8916481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.7711564622
MESH:D005234 Fatty Liver arsenic trioxide 21.5915073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 21.5912631006 16239168 61145 17595544 15959796 19224547 16045604 12795759
MESH:D005234 Fatty Liver Curcumin 21.5919297423
MESH:D005234 Fatty Liver Ethanol 21.5916409862 18620774 19236843
MESH:D005234 Fatty Liver Valproic Acid 21.5919224547 14986274
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.3317920746
MESH:D005264 Femoral Fractures zoledronic acid 5.5016234978
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.9716946407 10194807 15513904 15451040
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1411858732
MESH:D005315 Fetal Diseases Valproic Acid 4.5616575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.8218558336 8888407
MESH:D005334 Fever Indomethacin 3.8410431976 17627676 11852909
MESH:D005354 Fibrosarcoma Indomethacin 4.5710962813
MESH:D005355 Fibrosis Carbon Tetrachloride 24.3918705752
MESH:D005355 Fibrosis Curcumin 24.3918705752
MESH:D005355 Fibrosis Emodin 24.3919474275
MESH:D005355 Fibrosis Indomethacin 24.3917994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 24.3920067830
MESH:D005499 Folliculitis Indomethacin 4.8411298111
MESH:D005534 Foot Diseases Arsenic 5.236392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.9516904648
MESH:D005756 Gastritis Acetaminophen 17.1316983495
MESH:D005756 Gastritis Ethanol 17.1315046732
MESH:D005756 Gastritis Indomethacin 17.1315046732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.3818462866
MESH:D005909 Glioblastoma Curcumin 6.7917596214
MESH:D005909 Glioblastoma Indomethacin 6.7912870263
MESH:D005910 Glioma Indomethacin 3.1016487511 18371953
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.0311849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2610696789
MESH:D006073 Gout Indomethacin 5.0211248219
MESH:D006258 Head and Neck Neoplasms Cisplatin 11.8515102660 15464296
MESH:D006258 Head and Neck Neoplasms Curcumin 11.8518462866 18829502
MESH:D006258 Head and Neck Neoplasms Indomethacin 11.8515482327
MESH:D034381 Hearing Loss Cisplatin 4.0219898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.1515464296
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.1610048152 11294989
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0511000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.2815633222
MESH:D006505 Hepatitis Carbon Tetrachloride 3.2919110552 19900420
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.3715135802
MESH:D006529 Hepatomegaly perfluorooctanoic acid 7.613609246
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.6112621046 15340226 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.7217701891
MESH:D006558 Herpes Genitalis Estradiol 4.7015709030
MESH:D006561 Herpes Simplex Etoposide 9.0110809021
MESH:D006561 Herpes Simplex resveratrol 9.0116876885
MESH:D006689 Hodgkin Disease Bleomycin 11.0018501091 17606976 15147373
MESH:D006689 Hodgkin Disease Cisplatin 11.0016170182 16200630
MESH:D006689 Hodgkin Disease Etoposide 11.0017606976 16200630 18180244 15147373 16135485
MESH:D019584 Hot Flashes Estradiol 3.4217088409
MESH:D006849 Hydrocephalus Valproic Acid 4.5417688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.7118606429 16354765 15340226 16959395 8697196
MESH:D006930 Hyperalgesia Acetaminophen 21.8116870215
MESH:D006930 Hyperalgesia Ethanol 21.8118783367
MESH:D006930 Hyperalgesia Indomethacin 21.8112727271
MESH:D006930 Hyperalgesia perfluorooctanoic acid 21.8112083418
MESH:D006930 Hyperalgesia zoledronic acid 21.8116769263
MESH:D034321 Hyperamylasemia Indomethacin 5.3917883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.2116899240
MESH:D006934 Hypercalcemia zoledronic acid 4.7618089816 19622757
MESH:D006937 Hypercholesterolemia Curcumin 8.4218704882
MESH:D006937 Hypercholesterolemia resveratrol 8.4217188708
MESH:D006940 Hyperemia Indomethacin 4.6812524144
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.1717050553
MESH:D006949 Hyperlipidemias Indomethacin 8.5017546600
MESH:D006949 Hyperlipidemias resveratrol 8.5016873680
MESH:D006973 Hypertension Arsenic 4.809931084 11953799 16076760
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8018670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7715338365
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.3116612254
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.0217488730
MESH:D006987 Hypesthesia Arsenic 5.2316093927
MESH:D006996 Hypocalcemia zoledronic acid 5.8612669777
MESH:D007022 Hypotension Isoflurane 4.6412967683
MESH:D007077 Ileal Diseases Indomethacin 4.6918306037 10574470
MESH:D007079 Ileitis Indomethacin 5.0216133968 10647630 10651667
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.0416133044
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.3317600658
MESH:D007249 Inflammation Bleomycin 17.7417118201
MESH:D007249 Inflammation Curcumin 17.7417151092 16956363 18403477
MESH:D007249 Inflammation Indomethacin 17.7412568917 3291741 7812673
MESH:D007249 Inflammation perfluorooctanoic acid 17.7412083418
MESH:D007249 Inflammation resveratrol 17.7416366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 17.7412878042 12200463
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.0818200517 18596194
MESH:D007251 Influenza, Human resveratrol 4.2116624496
MESH:D007333 Insulin Resistance Estradiol 2.7616393666 16627594
MESH:D007410 Intestinal Diseases Indomethacin 4.0117329856 15610444 11686837 17994277 11855677 10210152 11713966 18236018 15831440
MESH:D007414 Intestinal Neoplasms Curcumin 3.9410783313
MESH:D019586 Intracranial Hypertension Indomethacin 5.0415241188
MESH:D007569 Jaw Abnormalities Ethanol 9.1515513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.1516580747
MESH:D007579 Jejunal Diseases Indomethacin 4.6916133968 18306037 10574470
MESH:D007642 Keratosis Arsenic 4.6612749816 16930632
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.8115464296
MESH:D007674 Kidney Diseases Acetaminophen 12.9215629191 12587719
MESH:D007674 Kidney Diseases Cisplatin 12.9215190930 18289764 19839026 12649298 12231392
MESH:D007674 Kidney Diseases Estradiol 12.9215618244
MESH:D007674 Kidney Diseases Indomethacin 12.9217190690
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 3.9816518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 6.5016705839
MESH:D007680 Kidney Neoplasms Estradiol 6.5015610895
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.4611231351
MESH:D007859 Learning Disorders Colchicine 9.2611749816
MESH:D007859 Learning Disorders Ethanol 9.2615451040
MESH:D007889 Leiomyoma Curcumin 4.2718555241
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.6412228301 11703811 10320625
MESH:D007938 Leukemia arsenic trioxide 5.9615070760
MESH:D007938 Leukemia Curcumin 5.9618462866
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 20.8312560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 20.8316106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Emodin 20.8317077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 20.8318089816
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.9816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 7.7614633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 7.7615631656 10785260 16572323
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.4719077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.8020471514 16968895 17050201 19850784 16467208
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 5.8018360721
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 5.8016294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 11.6017339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 11.6011161223 15748426 12679006 11468182 17649720 16112521 15622746 19075265 17869043 15336539 19225113 17217047 16823087 17107899 16966277 16891316 9834237 15213294 12018890 17712046 19035177 12712474 19642359 16330433 16331271
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 11.6016087638
MESH:D015458 Leukemia, T-Cell arsenic trioxide 10.6816882451
MESH:D015458 Leukemia, T-Cell Curcumin 10.6816106398
MESH:D007964 Leukocytosis Indomethacin 5.0416537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.3917980183
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.908812269
MESH:D017880 Limb Deformities, Congenital Ethanol 3.5817676605
MESH:D008080 Liposarcoma Paclitaxel 4.5217353645
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.3911479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.2111408273 11903743 17334410 17157831 21278145 16943688 16221502 16239168 17174718
MESH:D008103 Liver Cirrhosis Ethanol 6.2115289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.7718295389
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 10.2218251166 18472332 18395914 18705752 17761835 17976157 18210741 20821823 18429990 16136751 15338365 16638106 12632514 13678700 12546737 17869086 16027843 18205269 17708605 16033810 15123356 14620537 15673190 17944888 12586293 17900296 12898905 17766677 12741479 17823541 15730626 15052691 16248980 17565644 15818738 15370692 15996030 16097048 18412020 12958196 18339082 18006644 17557913 18166357 17714472 11481614 18376398 15893842 17805973 17922224 15362042 12666154 15925388 16116963 18481824 15057751 14748882 12389079 17481882 15959796 18054572 14724832 14512876 15931870 12445421 18279442 17640975 18277467 15876570 14716833 18263696 14716496 18418968 18472094 17631135 17698563 16192424 12632512 18156304 17525996 12667390 17721639 18395095 16015684 12609069 12445418 12649538 10355542 15650968 18420326 16011737 18187930 18317297
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 10.2217355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Emodin 10.2215288473
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 10.2214716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 10.2218166357
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 10.2218194892
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.2212878042
MESH:D008107 Liver Diseases Acetaminophen 8.6516610002 16611625 11587558 19014921 19784758 19460945 12587719 12969438
MESH:D008107 Liver Diseases Arsenic 8.6511134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.6516246199 15720792 15830285 17285989 16964402
MESH:D008107 Liver Diseases Curcumin 8.6516956363
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.3317347304 17207112
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8515123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.4716871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.4716899240 14706259
MESH:D008113 Liver Neoplasms Arsenic 19.9216368122
MESH:D008113 Liver Neoplasms arsenic trioxide 19.9214682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 19.9219294768
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 19.9218709148 14757943
MESH:D008113 Liver Neoplasms resveratrol 19.9219073162 20405173 19812893 19321006
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 19.9216984957
MESH:D008113 Liver Neoplasms zerumbone 19.9220452335
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 12.5120377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 12.5115583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Deoxycholic Acid 12.516150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 12.5112151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.1115213294
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.9317228818
MESH:D008175 Lung Neoplasms Arsenic 10.0119168569 17976673 17306315
MESH:D008175 Lung Neoplasms arsenic trioxide 10.0119825857 11798837
MESH:D008175 Lung Neoplasms Bleomycin 10.016189445
MESH:D008175 Lung Neoplasms Cisplatin 10.0111798837 6189445 17225452
MESH:D008175 Lung Neoplasms Curcumin 10.0116243823 18462866 19359593
MESH:D008175 Lung Neoplasms Indomethacin 10.0111497255 16537180 11053908
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.0119555203 11884234
MESH:D008223 Lymphoma Curcumin 7.1918462866
MESH:D008223 Lymphoma Etoposide 7.1912556972 12854902
MESH:D016393 Lymphoma, B-Cell resveratrol 4.0017088997
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 8.1214749477
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 8.1214749477
MESH:D016399 Lymphoma, T-Cell Curcumin 4.3816173963
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.9215688416
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 8.9411807958 16891317 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 8.9411606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 8.9417312309
MESH:D020149 Manganese Poisoning Estradiol 4.1519453300
MESH:D008545 Melanoma Bleomycin 9.1515577320
MESH:D008545 Melanoma Cisplatin 9.1512393984 18332650 16809738 11135225 18176117 15577323 16248763 18505091 12883367 16432458 17761969 17023156 12374674
MESH:D008545 Melanoma Curcumin 9.1517885582 18462866
MESH:D008545 Melanoma Paclitaxel 9.1512040289 12025231 16342250
MESH:D008545 Melanoma resveratrol 9.1517992120
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.4515990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2519513568
MESH:D008569 Memory Disorders Curcumin 8.7217263510
MESH:D008569 Memory Disorders Ethanol 8.7218411066 15451040
MESH:D008654 Mesothelioma Cisplatin 6.2617638057
MESH:D008654 Mesothelioma zoledronic acid 6.2616675582
MESH:D008659 Metabolic Diseases resveratrol 4.0917112576
MESH:D008881 Migraine Disorders Indomethacin 6.9511903285
MESH:D008881 Migraine Disorders Valproic Acid 6.9518765137 18803445
MESH:D009062 Mouth Neoplasms Indomethacin 3.7412636206
MESH:D009101 Multiple Myeloma arsenic trioxide 20.2414977855 11468182 15949261 19549372 19417148
MESH:D009101 Multiple Myeloma Curcumin 20.2419372569
MESH:D009101 Multiple Myeloma Paclitaxel 20.2414749477
MESH:D009101 Multiple Myeloma resveratrol 20.2417935668 17049120 14749477 16267019 17164350 16490592
MESH:D009101 Multiple Myeloma zoledronic acid 20.2418089719 16996129 19621390
MESH:D009134 Muscular Atrophy, Spinal Curcumin 11.3317962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 11.3317962980
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.748888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.3418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.7916882451 16105982
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 6.7917596541
MESH:D009203 Myocardial Infarction Cocaine 5.9518072171
MESH:D009203 Myocardial Infarction resveratrol 5.9517015251 17125593 16456233 16525036 16317513 17188708
MESH:D017202 Myocardial Ischemia Arsenic 13.8315371236
MESH:D017202 Myocardial Ischemia resveratrol 13.8317015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 13.8312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.0316810080
MESH:D009205 Myocarditis resveratrol 4.4317322642
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.5318551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 9.3016624393
MESH:D009361 Neoplasm Invasiveness Curcumin 9.3018495463
MESH:D009362 Neoplasm Metastasis Indomethacin 9.0111239499 11053908 16537180
MESH:D009362 Neoplasm Metastasis Paclitaxel 9.0115867366
MESH:D009362 Neoplasm Metastasis zoledronic acid 9.0119139120 17312309 15867366
MESH:D009369 Neoplasms Cisplatin 2.7916773208
MESH:D009374 Neoplasms, Experimental Indomethacin 8.3415625704 10663608
MESH:D009374 Neoplasms, Experimental resveratrol 8.348985016
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 4.2012497104
MESH:D009389 Neovascularization, Pathologic Estradiol 9.4817289903
MESH:D009389 Neovascularization, Pathologic parthenolide 9.4816921510
MESH:D009395 Nephritis, Interstitial Cisplatin 4.1615464296
MESH:D009421 Nervous System Malformations Estradiol 8.4416427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.4414600291
MESH:D009423 Nervous System Neoplasms Curcumin 5.3018462866
MESH:D009436 Neural Tube Defects Arsenic 10.9816620997
MESH:D009436 Neural Tube Defects arsenic trioxide 10.9810525206
MESH:D009436 Neural Tube Defects Valproic Acid 10.9816359493 8888407
MESH:D009447 Neuroblastoma Cisplatin 3.288761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 12.6118514411
MESH:D019636 Neurodegenerative Diseases Indomethacin 12.6112349958
MESH:D019636 Neurodegenerative Diseases resveratrol 12.6117652729
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.378761367
MESH:D020078 Neurogenic Inflammation Arsenic 9.7017056641
MESH:D020078 Neurogenic Inflammation resveratrol 9.7017929310
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.639802331
MESH:D009765 Obesity Curcumin 2.6719297423
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.846374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.1512819281 16049721
MESH:D010003 Osteoarthritis Indomethacin 3.477009135
MESH:D010014 Osteolysis Paclitaxel 11.2015867366
MESH:D010014 Osteolysis zoledronic acid 11.2015867366
MESH:D010024 Osteoporosis Curcumin 6.9818719352
MESH:D010024 Osteoporosis zoledronic acid 6.9817882678
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 3.9617513867
MESH:D010051 Ovarian Neoplasms Arsenic 17.4617306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 17.4612452020 16624393 19769630
MESH:D010051 Ovarian Neoplasms Cisplatin 17.4619769630 15464296 17225452 6897625
MESH:D010051 Ovarian Neoplasms Curcumin 17.4619020741 18462866
MESH:D010051 Ovarian Neoplasms Estradiol 17.4619401270
MESH:D010051 Ovarian Neoplasms Paclitaxel 17.4611161223
MESH:D010146 Pain Acetaminophen 9.9016870215
MESH:D010146 Pain Indomethacin 9.9017440234 13679232 17627676 3291741
MESH:D010146 Pain zoledronic acid 9.9016475674
MESH:D010149 Pain, Postoperative Indomethacin 4.3512538197 18702446
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 15.0415580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 15.0419003803
MESH:D010190 Pancreatic Neoplasms Curcumin 15.0417440100 19401701 19196508
MESH:D010190 Pancreatic Neoplasms Ethanol 15.0412384795
MESH:D010190 Pancreatic Neoplasms Etoposide 15.0419003803
MESH:D010195 Pancreatitis Indomethacin 3.6317883296 15028970
MESH:D010212 Papilloma Hydrogen Peroxide 3.7712065085
MESH:D010235 Paraganglioma arsenic trioxide 3.8619927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.3916537180
MESH:D020734 Parkinsonian Disorders Indomethacin 3.8412349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.3911903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9212520081
MESH:D010437 Peptic Ulcer Indomethacin 4.8211148446
MESH:D010518 Periodontitis Indomethacin 4.5817225004
MESH:D010523 Peripheral Nervous System Diseases Arsenic 9.0316093927
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 9.0315464296
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.6616905509 6392382 15371236
MESH:D010538 Peritonitis Isoflurane 4.9117414419
MESH:D010997 Pleural Neoplasms Cisplatin 5.0117638057
MESH:D011014 Pneumonia Bleomycin 5.0818024389 17071938 16317386
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2518163543
MESH:D047928 Premature Birth Indomethacin 4.8117000239
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 20.5917132714
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 20.5916679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 20.5911399792 11118676 11222880 11896295
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 20.5920603192
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5920887781
MESH:D011471 Prostatic Neoplasms Arsenic 2.8316140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.8319131511
MESH:D011471 Prostatic Neoplasms Curcumin 2.8311398177 18226269 18769126 15129424 18156803 12497104 10851300
MESH:D011471 Prostatic Neoplasms Estradiol 2.8316740699
MESH:D011471 Prostatic Neoplasms Etoposide 2.8317172428
MESH:D011471 Prostatic Neoplasms Paclitaxel 2.8317172428 17136230 16356831 16729912
MESH:D011471 Prostatic Neoplasms parthenolide 2.8316921510
MESH:D011471 Prostatic Neoplasms resveratrol 2.8317804756 16731767 17718901 15767336 17636462 17675339
MESH:D011471 Prostatic Neoplasms zoledronic acid 2.8312438248 19103299
MESH:D011507 Proteinuria Arsenic 8.4921343184
MESH:D011507 Proteinuria Indomethacin 8.4911849393
MESH:D019310 Pseudolymphoma Valproic Acid 4.2111422049 12752131
MESH:D011618 Psychotic Disorders Cocaine 4.5916134406
MESH:D011654 Pulmonary Edema Bleomycin 4.9915808516
MESH:D011656 Pulmonary Emphysema Curcumin 4.2519168576
MESH:D011658 Pulmonary Fibrosis Bleomycin 3.7417177178 18162602 15322207 11554783 17434272 12624602 18008008 14609568 12574379 17241526 15541506 16314464 16115399 21435439
MESH:D012021 Reflex, Abnormal Pentobarbital 5.6910930210
MESH:D051437 Renal Insufficiency Cisplatin 4.0915464296
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.2516325855
MESH:D015427 Reperfusion Injury resveratrol 3.1116314181 17520802 15827377 17058453 16317513
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.7310666014 18379247
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5318990726
MESH:D012208 Rhabdomyosarcoma Valproic Acid 3.8719155313
MESH:D012509 Sarcoma Curcumin 3.8418462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 22.1116646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 22.1114601052
MESH:D012512 Sarcoma, Ewing's Etoposide 22.1114601052
MESH:D012512 Sarcoma, Ewing's zoledronic acid 22.1116121404
MESH:D012559 Schizophrenia Valproic Acid 2.0315737665 19110320
MESH:D012640 Seizures 2,4-dinitrotoluene 16.2918551238
MESH:D012640 Seizures Cocaine 16.2910454489
MESH:D012640 Seizures Ethanol 16.299754883
MESH:D012640 Seizures Pentobarbital 16.299754883 10087439
MESH:D012640 Seizures Valproic Acid 16.291511512 17978042 11044598 14763951 3137016 11738929 15475178 16876388
MESH:D018805 Sepsis Curcumin 8.9418389075
MESH:D018805 Sepsis Isoflurane 8.9417414419
MESH:D012871 Skin Diseases Arsenic 2.6616353154 6392382 19834688 17548696 18709164 16759981 17453740 17050553 15952646 17938729 16702368
MESH:D012878 Skin Neoplasms Arsenic 12.3217029826 15504454 16251483 17976673 17050553 19538983
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 12.3212065085
MESH:D012878 Skin Neoplasms resveratrol 12.3215837718 8985016
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.3216192470
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 5.0115464296
MESH:D016135 Spinal Dysraphism Valproic Acid 3.5319490988
MESH:D013226 Status Epilepticus Valproic Acid 4.2112833885
MESH:D013272 Stomach Diseases Indomethacin 4.0918209964 10486359 10192188 10215738 16280098 15472012 16113693 18545984 17638125 16184426 17207306 17160473 15038085
MESH:D013274 Stomach Neoplasms arsenic trioxide 6.0317007042
MESH:D013274 Stomach Neoplasms Cisplatin 6.0318396642 17522103 15958060
MESH:D013274 Stomach Neoplasms Ethanol 6.0318456281
MESH:D013274 Stomach Neoplasms Indomethacin 6.0315609394
MESH:D013274 Stomach Neoplasms Paclitaxel 6.0318506536 18396642
MESH:D013276 Stomach Ulcer Curcumin 10.5316631530 19188055
MESH:D013276 Stomach Ulcer Ethanol 10.5311906479 17189318 17918041 16755016 9562338 9211565
MESH:D013276 Stomach Ulcer Indomethacin 10.5317657623 11145282 10423059 12498302 1323529 18431645 17918041 16755016 11906479 18209962 16169175 18299717 16631530 11729361 16934674 18087811 17895592 11595415 10878458 11595431 18193104 11523592 17977527 18726076 15138204 17654042 16252198 17627676 15255614 16397915 18543354 18237397 15104355 17135157 18181030 10750652 12467913 14567935 12077510 12500499 12787963 16150113
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.2016321402
MESH:D013375 Substance Withdrawal Syndrome Ethanol 9.329754883
MESH:D013375 Substance Withdrawal Syndrome Pentobarbital 9.3211529278 9754883
MESH:D024801 Tauopathies Paclitaxel 4.4916930453
MESH:D013733 Testicular Diseases pyrazole 4.496499806
MESH:D013736 Testicular Neoplasms Cisplatin 4.3315464296 17225452
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5712697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 6.6019014326
MESH:D013964 Thyroid Neoplasms Indomethacin 6.6014736730 11352223 18791128
MESH:D013978 Tibial Fractures Estradiol 4.3519048282
MESH:D014062 Tongue Neoplasms resveratrol 3.9316227395
MESH:D016171 Torsades de Pointes arsenic trioxide 3.6415213294
MESH:D014178 Translocation, Genetic Valproic Acid 4.9017262798
MESH:D014456 Ulcer Indomethacin 4.5710574470 17380554
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.193119515
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 14.4116049721
MESH:D001749 Urinary Bladder Neoplasms Arsenic 14.4111144890 19429237 19322015 15987713 18640142 17306315 17976673
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 14.4112973940 20435036 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 14.4117225452 12973940 15464296
MESH:D001749 Urinary Bladder Neoplasms Curcumin 14.4118593936
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.328888407
MESH:D014565 Urogenital Neoplasms Curcumin 4.9418462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.9910091137
MESH:D014581 Urticaria Acetaminophen 2.6810982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 8.7916803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 8.7917473185
MESH:D014594 Uterine Neoplasms resveratrol 3.8317044934
MESH:D014625 Vaginal Neoplasms Cisplatin 4.2915577323
MESH:D014652 Vascular Diseases Arsenic 4.4117056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2612125929
MESH:D018487 Ventricular Dysfunction, Left resveratrol 3.9817488730
MESH:D014839 Vomiting Cisplatin 10.4311897121
MESH:D014839 Vomiting Indomethacin 10.4311897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9215886252
MESH:D015431 Weight Loss Bleomycin 5.3212624602
Pathway ID Pathway Name
KEGG:04920 Adipocytokine signaling pathway
KEGG:04210 Apoptosis
REACT:578 Apoptosis
KEGG:04144 Endocytosis
KEGG:05160 Hepatitis C
KEGG:04010 MAPK signaling pathway
KEGG:04380 Osteoclast differentiation
KEGG:05200 Pathways in cancer
KEGG:04141 Protein processing in endoplasmic reticulum
KEGG:04622 RIG-I-like receptor signaling pathway
REACT:6900 Signaling in Immune system
KEGG:05222 Small cell lung cancer
KEGG:04120 Ubiquitin mediated proteolysis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA164742666
    • No data
    No data
    Releated drug ID Related drug Name
    PA449780glutathione
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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