Annotation Detail for TRO
Basic Information Top
| Gene Symbol: | TRO ( KIAA1114,MAGE-d3,MAGED3 ) |
|---|---|
| Gene Full Name: | trophinin |
| Band: | Xp11.21 |
| Quick Links | Entrez ID:7216; OMIM: 300132; Uniprot ID:TROP_HUMAN; ENSEMBL ID: ENSG00000067445; HGNC ID: 12326 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C015001 | arsenite | arsenite results in decreased expression of TRO mRNA | decreases expression | 18929588 |
| C015001 | arsenite | TRP53 protein affects the reaction [arsenite results in decreased expression of TRO mRNA] | affects reaction|decreases expression | 18929588 |
| D009151 | Mustard Gas | Mustard Gas results in increased expression of TRO mRNA | increases expression | 15674844 |
| D012643 | Selenium | Selenium results in increased expression of TRO mRNA | increases expression | 19244175 |
| D014810 | Vitamin E | Vitamin E results in increased expression of TRO mRNA | increases expression | 19244175 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D001249 | Asthma | Mustard Gas | 2.80 | 10378619 | |
| MESH:D001768 | Blister | Mustard Gas | 5.79 | 19167455 | |
| MESH:D001989 | Bronchiolitis Obliterans | Mustard Gas | 5.79 | 15286001 | |
| MESH:D029481 | Bronchitis, Chronic | Mustard Gas | 5.70 | 17687719 10378619 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Vitamin E | 4.49 | 16050911 | |
| MESH:D003092 | Colitis | Selenium | 4.34 | 17936198 | |
| MESH:D003110 | Colonic Neoplasms | arsenite | 2.63 | 15037631 | |
| MESH:D019465 | Craniofacial Abnormalities | Vitamin E | 1.93 | 19769572 | |
| MESH:D056486 | Drug-Induced Liver Injury | Selenium | 2.26 | 15131321 | |
| MESH:C538011 | Eales disease | Vitamin E | 5.43 | 9068938 | |
| MESH:D004487 | Edema | Mustard Gas | 3.73 | 11428647 9260866 11428631 11402378 | |
| MESH:D004890 | Erythema | Mustard Gas | 5.79 | 9357497 | |
| MESH:D005234 | Fatty Liver | arsenite | 4.20 | 18296743 | |
| MESH:D005355 | Fibrosis | arsenite | 4.63 | 18296743 | |
| MESH:D006330 | Heart Defects, Congenital | Vitamin E | 3.17 | 16080930 | |
| MESH:D006333 | Heart Failure | Selenium | 3.29 | 17162251 | |
| MESH:D006548 | Hernia, Diaphragmatic | Vitamin E | 2.81 | 16863852 16490937 | |
| MESH:D019584 | Hot Flashes | Vitamin E | 4.69 | 14716179 | |
| MESH:D007249 | Inflammation | Mustard Gas | 2.96 | 8975870 11428631 17524151 11428620 16001271 9357497 11428647 9260866 11402378 | |
| MESH:D007251 | Influenza, Human | Selenium | 13.50 | 16624496 | |
| MESH:D007251 | Influenza, Human | Vitamin E | 13.50 | 16624496 | |
| MESH:D007674 | Kidney Diseases | Vitamin E | 3.00 | 12488133 | |
| MESH:D007676 | Kidney Failure, Chronic | Selenium | 4.31 | 16518626 | |
| MESH:D008103 | Liver Cirrhosis | arsenite | 3.61 | 18296743 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Vitamin E | 1.91 | 16169303 | |
| MESH:D008171 | Lung Diseases | Mustard Gas | 8.39 | 18702808 18161513 | |
| MESH:D008171 | Lung Diseases | Vitamin E | 8.39 | 16863852 | |
| MESH:D008175 | Lung Neoplasms | arsenite | 3.78 | 16809336 | |
| MESH:D008175 | Lung Neoplasms | Mustard Gas | 3.78 | 8781369 3148597 | |
| MESH:D008175 | Lung Neoplasms | Vitamin E | 3.78 | 11062179 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Selenium | 2.99 | 15318939 | |
| MESH:D008654 | Mesothelioma | Selenium | 2.92 | 15107826 | |
| MESH:D009389 | Neovascularization, Pathologic | arsenite | 5.04 | 15738583 | |
| MESH:D009503 | Neutropenia | Mustard Gas | 4.43 | 7688884 16761898 | |
| MESH:D010954 | Plasmacytoma | Selenium | 5.61 | 15087411 | |
| MESH:D011041 | Poisoning | Mustard Gas | 4.26 | 15727166 | |
| MESH:D011471 | Prostatic Neoplasms | Vitamin E | 3.24 | 15084515 | |
| MESH:D011537 | Pruritus | Mustard Gas | 4.72 | 18058305 | |
| MESH:D011658 | Pulmonary Fibrosis | Mustard Gas | 3.05 | 17266442 17894541 17620002 17720292 10334151 | |
| MESH:D012871 | Skin Diseases | Mustard Gas | 5.29 | 12880345 15451306 16961503 | |
| MESH:D012871 | Skin Diseases | Vitamin E | 5.29 | 18709164 | |
| MESH:D020521 | Stroke | Vitamin E | 3.84 | 16517955 |
| No data |