AutismKB 2.0

Annotation Detail for TXK


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Basic Information Top
Gene Symbol:TXK ( BTKL,MGC22473,PSCTK5,PTK4,RLK,TKL )
Gene Full Name: TXK tyrosine kinase
Band: 4p12
Quick LinksEntrez ID:7294; OMIM: 600058; Uniprot ID:TXK_HUMAN; ENSEMBL ID: ENSG00000074966; HGNC ID: 12434
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04670Leukocyte transendothelial migration
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1869Behcet syndrome
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016599 mono-(2-ethylhexyl)phthalate mono-(2-ethylhexyl)phthalate results in increased expression of TXK mRNAincreases expression 16809437
No data
Pathway ID Pathway Name
KEGG:04670 Leukocyte transendothelial migration
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA37090
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA450379mercaptopurine
    PA450428methotrexate
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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