Annotation Detail for SLC35A2
Basic Information
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| Gene Symbol: | SLC35A2 ( UGALT,UGAT,UGT,UGT1,UGT2,UGTL ) |
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| Gene Full Name: | solute carrier family 35 (UDP-galactose transporter), member A2 |
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| Band: | Xp11.23 |
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| Quick Links | Entrez ID:7355; OMIM: 314375; Uniprot ID:S35A2_HUMAN; ENSEMBL ID: ENSG00000102100; HGNC ID: 11022 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| Transmembrane transport of small molecules |
| Pathway ID | Pathway Name |
|---|
| 500363 | Transport of nucleotide sugars |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000638 |
Amiodarone |
Amiodarone results in increased expression of SLC35A2 mRNA | increases expression | 19774075
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SLC35A2 mRNA | affects binding|decreases expression|increases activity | 19710929
|
| C006253 |
pirinixic acid |
pirinixic acid results in decreased expression of SLC35A2 mRNA | decreases expression | 18445702
|
| D014415 |
Tunicamycin |
Tunicamycin results in increased expression of SLC35A2 mRNA | increases expression | 17127020
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.64 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.22 | 16434500 |
| MESH:D001145 |
Arrhythmias, Cardiac |
|
Amiodarone |
4.25 | 20041841 18218290 18057881 |
| MESH:D001281 |
Atrial Fibrillation |
|
Amiodarone |
4.23 | 19698954 18651412 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
Amiodarone |
10.74 | 19483382 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
10.74 | 19483382 |
| MESH:D002311 |
Cardiomyopathy, Dilated |
|
Amiodarone |
3.01 | 19225199 15710769 |
| MESH:D002341 |
Carotid Artery Thrombosis |
|
Amiodarone |
5.83 | 18974383 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.15 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.59 | 18249437 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Amiodarone |
2.48 | 18218290 15265979 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.96 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
Amiodarone |
9.45 | 14986274 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
9.45 | 19236843 20131406 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.78 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
Amiodarone |
10.84 | 15265979 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
10.84 | 19772884 16221962 18467677 19176532 |
| MESH:D006937 |
Hypercholesterolemia |
|
Amiodarone |
4.36 | 9751232 8137927 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.63 | 20558911 |
| MESH:D007037 |
Hypothyroidism |
|
Amiodarone |
5.17 | 17991464 18020914 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.90 | 16306350 |
| MESH:D008064 |
Lipidoses |
|
Amiodarone |
3.82 | 17567588 15342952 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.94 | 16377806 20007298 15890375 |
| MESH:D008133 |
Long QT Syndrome |
|
Amiodarone |
3.92 | 15350150 17391786 11989578 |
| MESH:D008171 |
Lung Diseases |
|
Amiodarone |
3.65 | 12587719 |
| MESH:D017563 |
Lung Diseases, Interstitial |
|
Amiodarone |
5.34 | 18516814 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.16 | 16239165 |
| MESH:D009181 |
Mycoses |
|
Amiodarone |
5.77 | 17974566 12754197 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.29 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.29 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.12 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.89 | 20558911 |
| MESH:D011658 |
Pulmonary Fibrosis |
|
Amiodarone |
2.98 | 12832656 11597910 12490602 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.56 | 19058328 |
| OMIM:609620 |
SHORT QT SYNDROME 1 |
|
Amiodarone |
5.83 | 18724381 |
| MESH:D013276 |
Stomach Ulcer |
|
Amiodarone |
3.79 | 18087811 |
| MESH:D013610 |
Tachycardia |
|
Amiodarone |
4.87 | 11238279 |
| MESH:D017180 |
Tachycardia, Ventricular |
|
Amiodarone |
4.77 | 19225199 |
| MESH:D013959 |
Thyroid Diseases |
|
Amiodarone |
5.62 | 19731979 |
| MESH:D013971 |
Thyrotoxicosis |
|
Amiodarone |
5.51 | 18020914 19584973 |
| MESH:D016171 |
Torsades de Pointes |
|
Amiodarone |
4.93 | 17467628 11989578 |
| Pathway ID |
Pathway Name |
|---|
| REACT:15518 |
Transmembrane transport of small molecules |
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