AutismKB 2.0

Annotation Detail for UGDH


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:UGDH ( GDH,UDP-GlcDH,UDPGDH,UGD )
Gene Full Name: UDP-glucose 6-dehydrogenase
Band: 4p14
Quick LinksEntrez ID:7358; OMIM: 603370; Uniprot ID:UGDH_HUMAN; ENSEMBL ID: ENSG00000109814; HGNC ID: 12525
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-4821UDP-D-xylose and UDP-D-glucuronate biosynthesis
COLANSYN-PWYcolanic acid building blocks biosynthesis
Pathway IDPathway Name
hsa00520Amino sugar and nucleotide sugar metabolism
hsa00040Pentose and glucuronate interconversions
hsa01100Metabolic pathways
hsa00053Ascorbate and aldarate metabolism
hsa00500Starch and sucrose metabolism
Pathway IDPathway Name
Biological oxidations
No data
No data
Pathway IDPathway Name
500212Formation of the active cofactor, UDP-glucuronate
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C014211 2,3,7,8-tetrachlorodibenzofuran 2,3,7,8-tetrachlorodibenzofuran affects the expression of UGDH mRNAaffects expression 18343893
C014024 2,4,5,2',4',5'-hexachlorobiphenyl 2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of UGDH mRNAincreases expression 20005886
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of UGDH mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in decreased expression of UGDH mRNAdecreases expression 20406850
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of UGDH mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of UGDH mRNAdecreases expression 18648102
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of UGDH mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of UGDH mRNAaffects expression 17562736
D000111 Acetylcysteine Acetylcysteine results in increased expression of UGDH mRNAincreases expression 16084531
C103303 alitretinoin [pirinixic acid co-treated with alitretinoin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNAaffects cotreatment|decreases expression 16292757
D000643 Ammonium Chloride Ammonium Chloride affects the expression of UGDH mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of UGDH mRNAincreases expression 20458559
C032036 bromobenzene bromobenzene metabolite binds to UGDH proteinaffects binding 17305373
C030123 coumarin coumarin results in increased expression of UGDH mRNAincreases expression 18480146
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of UGDH mRNAincreases expression 17654400
D016572 Cyclosporine Cyclosporine results in decreased expression of UGDH mRNAdecreases expression 20106945
D002945 Cisplatin Cisplatin results in increased expression of UGDH proteinincreases expression 16803524
D004041 Dietary Fats Dietary Fats results in decreased expression of UGDH mRNAdecreases expression 15238619
18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of UGDH mRNAincreases expression 19638242
C045651 epigallocatechin gallate epigallocatechin gallate results in increased expression of UGDH mRNAincreases expression 16084531
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of UGDH mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of UGDH mRNAincreases expression 19619570
D000431 Ethanol Ethanol results in decreased expression of UGDH mRNAdecreases expression 17920746
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of UGDH mRNAincreases expression 17942748
D005038 Ethylnitrosourea Ethylnitrosourea results in increased mutagenesis of UGDH geneincreases mutagenesis 15755804
D005054 Eugenol Eugenol results in increased expression of UGDH mRNAincreases expression 16292757
D005472 Fluorouracil UGDH protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
C056933 fumonisin B1 fumonisin B1 results in increased expression of UGDH mRNAincreases expression 16221962
C106014 gedunin gedunin results in increased expression of UGDH mRNAincreases expression 17010675
D019833 Genistein Genistein results in increased expression of UGDH mRNAincreases expression 16865672
15378649
D007529 Isoflavones Isoflavones results in increased expression of UGDH mRNAincreases expression 17374662
C002950 methylformamide methylformamide affects the expression of UGDH mRNAaffects expression 17040096
C002950 methylformamide methylformamide analog affects the expression of UGDH mRNAaffects expression 17040096
C008493 methylselenic acid methylselenic acid affects the expression of UGDH mRNAaffects expression 14617803
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in decreased expression of UGDH mRNAdecreases expression 17616710
C041786 palm oil palm oil results in decreased expression of UGDH mRNAdecreases expression 18042831
C008922 piperine piperine results in decreased expression of UGDH mRNAdecreases expression 16292757
C006253 pirinixic acid [pirinixic acid co-treated with alitretinoin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNAaffects cotreatment|decreases expression 16292757
C006253 pirinixic acid pirinixic acid results in decreased expression of UGDH mRNAdecreases expression 18445702
C006253 pirinixic acid pirinixic acid results in increased expression of UGDH mRNAincreases expression 15375163
16221962
D011794 Quercetin Quercetin results in decreased expression of UGDH proteindecreases expression 18095365
D012293 Rifampin [Rifampin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNAaffects cotreatment|decreases expression 16292757
D012293 Rifampin Rifampin results in increased expression of UGDH mRNAincreases expression 16292757
C009277 sodium arsenate sodium arsenate results in increased expression of UGDH mRNAincreases expression 16882884
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of UGDH mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of UGDH mRNAdecreases expression 19619570
D013749 Tetrachlorodibenzodioxin NFE2L2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of UGDH mRNA]affects reaction|increases expression 19474220
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of UGDH mRNAaffects expression 18343893
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of UGDH mRNAaffects binding|increases expression 16214954
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of UGDH mRNAincreases expression 17949056
16960034
19474220
16611356
15328365
18796159
15800033
20005886
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of UGDH mRNAincreases expression 16960034
D013827 Thiabendazole Thiabendazole results in increased expression of UGDH mRNAincreases expression 18539377
C050414 tripterine tripterine results in increased expression of UGDH mRNAincreases expression 17010675
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 11.847525203
MESH:D000014 Abnormalities, Drug-Induced Ethanol 11.8417676605 18926900
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 11.8415322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 9.0418287403
MESH:D000138 Acidosis Ethanol 9.0411192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5017505938
MESH:D058186 Acute Kidney Injury Cisplatin 3.5812690470 15814532 17670903
MESH:D055371 Acute Lung Injury pirinixic acid 2.7218653653
MESH:D000230 Adenocarcinoma arsenic trioxide 15.4619825857 11798837
MESH:D000230 Adenocarcinoma Cisplatin 15.4617638652 11798837
MESH:D000230 Adenocarcinoma Estradiol 15.4611473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 15.4614692618
MESH:D000230 Adenocarcinoma Fluorouracil 15.4617638652
MESH:D000230 Adenocarcinoma Genistein 15.4611473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 9.773712494
MESH:D000236 Adenoma Diethylnitrosamine 9.7710737359 6695378
MESH:D000236 Adenoma Ethylnitrosourea 9.776695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 14.7817162532 19061943 17620307 19052882 18056438 16434500
MESH:D018248 Adenoma, Liver Cell pirinixic acid 14.7816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 14.7816835633
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.8815451039 15451040
MESH:D000505 Alopecia Isoflavones 4.3817569567
MESH:D000740 Anemia Fluorouracil 7.4416511603 17963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.4411748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.8517084956
MESH:D000799 Angioedema Acetaminophen 3.4010982225
MESH:D000853 Anophthalmos Ethanol 4.4015513904
MESH:D001008 Anxiety Disorders Ethanol 3.6611141031
MESH:D001161 Arteriosclerosis Dietary Fats 8.5115238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.5111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.3915885639
MESH:D001249 Asthma epigallocatechin gallate 3.2516516891
MESH:D001260 Ataxia Telangiectasia Quercetin 4.5515336622
MESH:D001321 Autistic Disorder Acetaminophen 1.4718445737
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 9.6819761891
MESH:D001327 Autoimmune Diseases Quercetin 9.6819761891
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.581440618 11289319
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 13.0516206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.0519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.0512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4815746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.4514601052
MESH:D001927 Brain Diseases Ethylnitrosourea 4.5114991843
MESH:D001932 Brain Neoplasms Ethylnitrosourea 3.9215144691 16357521 16436596 18412241 16651633
MESH:D001943 Breast Neoplasms alitretinoin 5.3216344269
MESH:D001943 Breast Neoplasms Cisplatin 5.3218382427 19526202
MESH:D001943 Breast Neoplasms Dietary Fats 5.3220435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 5.3217474063
MESH:D001943 Breast Neoplasms Estradiol 5.3212948864 14630087 19861407 17289903 17261762 17018787 16675129 18497071
MESH:D001943 Breast Neoplasms Fluorouracil 5.3219217205 18608205 15136595 16557594 16110121 16595493 18357371
MESH:D001943 Breast Neoplasms Genistein 5.3216873071 17200150 16541309
MESH:D001943 Breast Neoplasms Quercetin 5.3218628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.3220435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9311589617
MESH:D002056 Burns Ethanol 4.2316374292
MESH:D002105 Cadmium Poisoning Quercetin 5.1116962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0316111702
MESH:D002276 Carcinoid Tumor Fluorouracil 4.2316051944
MESH:D002277 Carcinoma Fluorouracil 7.0617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.0616835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 27.2416705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 27.2416705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 27.243581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 27.243084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 27.2414691202 11135700 15073043 15553829 16217749
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 27.2417982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 27.243084413 17428255 18210153 20432363 16779866 19919837 21159647 18665156 17978847 16878318 16288022 20524982 19335982 17055752 19701751 19107877 17138121 19383236 17761372 16830150 17173139 16935385 19052882 20007298 18393292 18494052 19822196 20084675 19171122 20101231 19539802 20727157 3581430 17162532 18785209 16681979 18691550 16569478 10672840 20514400 19394651 16502159 18971187 19519916 20935162 18978308 18056438 11831363 16698587 16328049 20512989 16540662 19208518 18788625 18506893 16807293 19418558 20214788 10737359
MESH:D006528 Carcinoma, Hepatocellular Estradiol 27.2416924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 27.2415763234 15289165 18788625
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 27.2417971768 18930000 17088986 16332177 17045692 16799960
MESH:D006528 Carcinoma, Hepatocellular Genistein 27.2416924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 27.2419519916 12508355
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.8816685392 12023789
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.5317234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.4319014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 5.787296757
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 5.7818695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7412490120
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 6.9217015178
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 6.926189445 18337622 17066447
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 6.9216280240 17066447 16757204 18986760
MESH:D006332 Cardiomegaly Ethanol 10.0219332462
MESH:D006332 Cardiomegaly Quercetin 10.0219794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 10.0216120746 18850075 18670907
MESH:D002318 Cardiovascular Diseases Genistein 6.7616332659
MESH:D002318 Cardiovascular Diseases Isoflavones 6.7617689850
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 6.5514694615
MESH:D002386 Cataract Acetaminophen 6.5510977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 27.206135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 27.207505956
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 27.2018226522
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 27.2012371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 27.2021159647 7505956 2727394 17174075
MESH:D002471 Cell Transformation, Neoplastic Estradiol 27.2018566989
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 27.2016003739
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.5417160924
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.1219052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.1216835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 16.5819486331 9022650
MESH:D002779 Cholestasis Cyclosporine 16.5819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 16.5817333356 11677210 17110522 16105132 16919318 15861022 17681005
MESH:D002779 Cholestasis pirinixic acid 16.5819176532
MESH:D002971 Cleft Lip Ethanol 3.3515513904
MESH:D002972 Cleft Palate Ethanol 5.3015513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.3015668235 8697196 12621046 16354765 15340226
MESH:D003110 Colonic Neoplasms Fluorouracil 5.3218772588 17018589 17725105 15001691 17172411 17287894 17169374 16340194 17016597 16510598
MESH:D003110 Colonic Neoplasms Genistein 5.3217182828
MESH:D003110 Colonic Neoplasms Quercetin 5.3217191121 15741050 19056647 11134977 16640504 19440933 17148506
MESH:D015179 Colorectal Neoplasms arsenic trioxide 5.9520501625
MESH:D015179 Colorectal Neoplasms Cisplatin 5.9515273666
MESH:D015179 Colorectal Neoplasms Fluorouracil 5.9518802399 16331619 16391804 18509181 17594712 17454858 18288408 14970324 20501625 18383874 18448328 15289873 17255274 15148649 18949393 16303861 16282729 17401013 17695437 17094418 16524972 17016601
MESH:D015179 Colorectal Neoplasms Isoflavones 5.9517116718
MESH:D015179 Colorectal Neoplasms Quercetin 5.9518095365 18852136
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 7.9815095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.9814669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.9910525206
MESH:D019465 Craniofacial Abnormalities Ethanol 4.9919302082 15451040 11198716 10194807 15451039 15513904 11873399
MESH:D019465 Craniofacial Abnormalities sodium arsenate 4.9910525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.9920055451 10048152 15322242
MESH:D003490 Cyanosis 2,4-dinitrotoluene 9.4918551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 9.4918551238
MESH:D003550 Cystic Fibrosis Acetylcysteine 4.0119747007
MESH:D007644 Darier Disease Fluorouracil 4.3616733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7015213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.4111298694 2524372 8156756 12868966 8970840 14531868 18759878 11906362
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2218249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.102952479 3621924
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.3819496084
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 12.3319647726
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 12.3320387270
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 12.3316988119
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 12.3316647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 12.3317107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.0519279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 37.6421346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 37.6421346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 37.649022650 16192314 18692083 18648102 18289764 9328219 6482804 1440618 11289319 6679447 8291058 7440962 9653073
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 37.6421346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 37.6410774834 12958197 16485898 17906064 16109766 15619225 19370779 19739265 14986274 14725611 17562736 18713872 19085960 16781746 12392966 11529661 16081117 11287661 16177239 12540782 12594235 10663392 19923254 12153990 16227642 10915739 11834606 11739529 16393943 11743745 19164858 12705907 19420014 14550746 2444490 15968718 18071297 11461765 17522070 19416960 11421492
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 37.6411287661
MESH:D056486 Drug-Induced Liver Injury bromobenzene 37.6410092053 12628495
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 37.6417654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 37.6419107877
MESH:D056486 Drug-Induced Liver Injury Ethanol 37.6411566570
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 37.6416221962
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 37.6418186108
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 37.6420420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6619426721
MESH:D004362 Drug Toxicity Cisplatin 7.1119839026 12649298 12231392 15033597
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.1111462148
MESH:D050171 Dyslipidemias Dietary Fats 3.1418367378
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.5418357618
MESH:D004487 Edema pirinixic acid 5.2912083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.2911000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.4618230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.7812538720
MESH:D004714 Endometrial Hyperplasia Genistein 4.1616402032
MESH:D016889 Endometrial Neoplasms Estradiol 6.5519148513 18566989 11473722
MESH:D016889 Endometrial Neoplasms Genistein 6.5511473722
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.6510568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6816302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 15.793581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 15.7912903497
MESH:D004938 Esophageal Neoplasms Cisplatin 15.7916481741 16785472 17638652 15464296 15173087
MESH:D004938 Esophageal Neoplasms Ethanol 15.7916704527
MESH:D004938 Esophageal Neoplasms Fluorouracil 15.7916785472 16481741 16337965 17638652 15173087
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 15.7915623463 15878914 16805852 15547733 15264214 16510608 16704527 15547721 15150132
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.6911564622
MESH:D005234 Fatty Liver arsenic trioxide 31.0715073043
MESH:D005234 Fatty Liver Cyclosporine 31.0719224547
MESH:D005234 Fatty Liver Dietary Fats 31.0717967931 18296743 19004024 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 31.0721071580 20387270
MESH:D005234 Fatty Liver Ethanol 31.0716409862 18620774 19236843
MESH:D005234 Fatty Liver Ethinyl Estradiol 31.0715345470
MESH:D005234 Fatty Liver pirinixic acid 31.0719236843 20131406
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.2217920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.8715451040 10194807 16946407 15513904
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0411858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.586705139
MESH:D005355 Fibrosis Cyclosporine 17.7012639820 12168785
MESH:D005355 Fibrosis Dietary Fats 17.7018296743
MESH:D005355 Fibrosis Quercetin 17.7019474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 17.7020067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8516904648
MESH:D005756 Gastritis Acetaminophen 9.6716983495
MESH:D005756 Gastritis Ethanol 9.6715046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.798708960
MESH:D005909 Glioblastoma Ethylnitrosourea 10.3916436596
MESH:D005909 Glioblastoma Genistein 10.3916598420
MESH:D005909 Glioblastoma Quercetin 10.3919804834
MESH:D005910 Glioma Ethylnitrosourea 8.9616651633 16357521 18412241
MESH:D005910 Glioma Fluorouracil 8.9616145905
MESH:D005910 Glioma Quercetin 8.9617643826
MESH:D018149 Glucose Intolerance sodium arsenate 4.6819446573
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.647505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1510696789
MESH:D006258 Head and Neck Neoplasms Cisplatin 7.0115102660 15464296
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.0118337622 15102660 15162350
MESH:D034381 Hearing Loss Cisplatin 3.9319898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.0715464296
MESH:D006330 Heart Defects, Congenital 2,3,7,8-tetrachlorodibenzofuran 6.1911294989
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.1910048152 11294989
MESH:D006333 Heart Failure pirinixic acid 2.2720558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9511000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.116705139
MESH:D006529 Hepatomegaly fumonisin B1 12.0616221962
MESH:D006529 Hepatomegaly pirinixic acid 12.0616221962 18467677 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.0615340226 16120746 12621046
MESH:D006558 Herpes Genitalis Estradiol 4.5915709030
MESH:D006689 Hodgkin Disease Cisplatin 3.2416170182 16200630
MESH:D006734 Horse Diseases Thiabendazole 5.8316402567
MESH:D019584 Hot Flashes Estradiol 8.9617088409
MESH:D019584 Hot Flashes Isoflavones 8.9617290160 14716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6116354765 15340226 8697196 18606429 16959395
MESH:D006930 Hyperalgesia Acetaminophen 6.6916870215
MESH:D006930 Hyperalgesia Ethanol 6.6918783367
MESH:D006937 Hypercholesterolemia Dietary Fats 3.2121332399
MESH:D006943 Hyperglycemia pirinixic acid 8.0020558911
MESH:D006943 Hyperglycemia Quercetin 8.0011834736 18262572
MESH:D006949 Hyperlipidemias Dietary Fats 3.2221332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.5215034207
MESH:D006973 Hypertension Cyclosporine 7.5310903974
MESH:D006973 Hypertension Quercetin 7.5318356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.5318850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3916945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.2017937319
MESH:D007249 Inflammation Dietary Fats 6.9120412841
MESH:D007249 Inflammation Diethylnitrosamine 6.9118785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 6.9112200463 12878042
MESH:D007251 Influenza, Human Quercetin 4.0716624496
MESH:D007333 Insulin Resistance Dietary Fats 10.6311836018 18457598
MESH:D007333 Insulin Resistance Estradiol 10.6316627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 10.6316306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.589022650 8074119
MESH:D007569 Jaw Abnormalities Ethanol 8.8415513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.8416580747
MESH:D007627 Keloid Quercetin 4.5317086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0015604871
MESH:D017492 Keratosis, Seborrheic alitretinoin 5.2116144296
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.7015464296
MESH:D007674 Kidney Diseases Acetaminophen 16.3312587719 15629191
MESH:D007674 Kidney Diseases Cisplatin 16.3318289764 15190930 12649298 19839026 12231392
MESH:D007674 Kidney Diseases Cyclosporine 16.3310903974 8314463 18776723
MESH:D007674 Kidney Diseases Estradiol 16.3315618244
MESH:D007674 Kidney Diseases Quercetin 16.3316962696
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 29.6916705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 29.6916705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 29.696582329
MESH:D007680 Kidney Neoplasms Cyclosporine 29.6912371664
MESH:D007680 Kidney Neoplasms Estradiol 29.6915610895
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 29.6917379185
MESH:D007680 Kidney Neoplasms Fluorouracil 29.6916985049
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.3611231351
MESH:D007859 Learning Disorders Ethanol 3.7915451040
MESH:D007938 Leukemia arsenic trioxide 9.2315070760
MESH:D007938 Leukemia Genistein 9.2317468513 18980019
MESH:D007938 Leukemia Quercetin 9.2317468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.4117077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.8816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1114633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.3819077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.0617050201 16968895 20471514 16467208 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.9315748426 12712474 16330433 19075265 17217047 16823087 19035177 16112521 12018890 15622746 15336539 16966277 16331271 16891316 9834237 17107899 12679006 19642359 17649720 19225113 15213294 17869043 17712046 11161223 11468182
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.9416882451
MESH:D017880 Limb Deformities, Congenital Ethanol 3.5017676605
MESH:D008103 Liver Cirrhosis Dietary Fats 9.6618296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 9.6619638242 18665156 18522880 20032147 18407596
MESH:D008103 Liver Cirrhosis Ethanol 9.6615289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.6618295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.929327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 9.9117481882
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 9.9114716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 9.9118166357
MESH:D008106 Liver Cirrhosis, Experimental Genistein 9.9117823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 9.9115474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 9.9112741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 9.9112878042
MESH:D008107 Liver Diseases Acetaminophen 3.4916610002 12969438 11587558 16611625 19460945 12587719 19014921 19784758
MESH:D008107 Liver Diseases Diethylnitrosamine 3.4917034775
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.2317207112 17347304
MESH:D017114 Liver Failure, Acute Acetaminophen 2.8617185352 16871587
MESH:D008113 Liver Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 22.7918644402 16835634
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 22.797678174
MESH:D008113 Liver Neoplasms arsenic trioxide 22.7914682389
MESH:D008113 Liver Neoplasms Diethylnitrosamine 22.7912112319 9163691 19499222 20434301 19833225 19294768 20452335 20118626 18644402 18978307 18754104 16942905 12771043 19256749 19638242 21278145 19812893 20501860 19073162 19996281 20137499 21071580 21047994 20101389 19690152 15885732 19427195 15175105 19255062 2862719 19642983 18648771 19090486 20583210 19426721 2422723 20405173 18977376 21167192 20492335 10737359 19551842 19254457 19850985
MESH:D008113 Liver Neoplasms Fluorouracil 22.7915113037 18383874 17045692 16603448
MESH:D008113 Liver Neoplasms pirinixic acid 22.7920007298 16377806 15890375
MESH:D008113 Liver Neoplasms Quercetin 22.7918980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 22.7916984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 19.796135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 19.793712494 598648 6587162 1399818
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 19.7920377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 19.7918775883 18308698 3124819 9362446 18093689 17854601 18079962 17174075 18544905 21159647 18282651 16842330 18253720 19519916 17942915 19009564 19004024 19539802 2563599 18164116 19126423 16267830
MESH:D008114 Liver Neoplasms, Experimental Quercetin 19.7919519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 19.7912151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0215213294
MESH:D008171 Lung Diseases Acetylcysteine 3.7612815614
MESH:D008175 Lung Neoplasms alitretinoin 11.8416413115
MESH:D008175 Lung Neoplasms arsenic trioxide 11.8411798837 19825857
MESH:D008175 Lung Neoplasms Cisplatin 11.8417225452 11798837 6189445
MESH:D008175 Lung Neoplasms Diethylnitrosamine 11.846695378 21163286 20512841 20970405
MESH:D008175 Lung Neoplasms Ethylnitrosourea 11.8416019985 16271038 6695378 17703301
MESH:D008175 Lung Neoplasms Fluorouracil 11.8415246190
MESH:D008175 Lung Neoplasms Quercetin 11.8416280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 11.8411884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 11.8515086387
MESH:D008178 Lupus Erythematosus, Cutaneous Rifampin 11.8511422169
MESH:D008180 Lupus Erythematosus, Systemic Rifampin 3.8411422169
MESH:D008223 Lymphoma Ethylnitrosourea 3.6315790496
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 4.6315375218
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 8.4716891317 11807958 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 8.4710767621 10838139 18041768
MESH:D008325 Mammary Neoplasms, Experimental Genistein 8.4712929590 14578162
MESH:D020149 Manganese Poisoning Estradiol 4.0419453300
MESH:D008545 Melanoma Cisplatin 3.6111135225 15577323 12883367 16248763 18332650 17023156 12374674 16432458 17761969 18176117 12393984 18505091 16809738
MESH:D008545 Melanoma epigallocatechin gallate 3.6111746506 17992120
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.3415990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1519513568
MESH:D008569 Memory Disorders Ethanol 3.7818411066 15451040
MESH:D008579 Meningioma Ethylnitrosourea 5.5417943659
MESH:D008654 Mesothelioma Cisplatin 3.0617638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3516801185
MESH:D009062 Mouth Neoplasms Fluorouracil 3.3016757204 18986760
MESH:D009101 Multiple Myeloma arsenic trioxide 2.8015949261 11468182 14977855 19549372 19417148
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 5.0617962980
MESH:D009135 Muscular Diseases pirinixic acid 3.0916239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.4718186108
MESH:D009164 Mycobacterium Infections Rifampin 5.1118474467
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.2318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 2.8916105982 16882451
MESH:D009203 Myocardial Infarction Genistein 8.3617141266
MESH:D009203 Myocardial Infarction pirinixic acid 8.3619151258
MESH:D009203 Myocardial Infarction Quercetin 8.3619595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 17.5816810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 17.5817141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 17.5816411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 17.5819207477
MESH:D009336 Necrosis 2,4-dinitrotoluene 8.9118551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 8.9118551238 7678174
MESH:D009349 Nematode Infections Thiabendazole 5.9816402567
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.5516624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.513581430
MESH:D009362 Neoplasm Metastasis Acetylcysteine 8.5114720322
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.519029167 3581430
MESH:D009369 Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 16.888820588
MESH:D009369 Neoplasms alitretinoin 16.8816946489
MESH:D009369 Neoplasms Cisplatin 16.8816773208
MESH:D009369 Neoplasms Fluorouracil 16.8816928823 18600527 18239605
MESH:D009369 Neoplasms pirinixic acid 16.8817405874
MESH:D009369 Neoplasms Quercetin 16.8815185748
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 3.9916707424
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3017289903
MESH:D009395 Nephritis, Interstitial Cisplatin 4.0615464296
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0017954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.9219348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 14.0011399458 16427766
MESH:D009421 Nervous System Malformations Genistein 14.0016427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 14.0014600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 15.066679447
MESH:D009436 Neural Tube Defects Acetylcysteine 15.0619446573
MESH:D009436 Neural Tube Defects arsenic trioxide 15.0610525206
MESH:D009436 Neural Tube Defects sodium arsenate 15.0610525206 19446573 18186108 11749123
MESH:D009442 Neurilemmoma Ethylnitrosourea 4.9817160924 16003739 16651423
MESH:D009447 Neuroblastoma Cisplatin 3.228761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.0218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.0220387270
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.278761367
MESH:D020078 Neurogenic Inflammation Quercetin 3.9617929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6820387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.1416436463
MESH:D009765 Obesity Dietary Fats 4.0221332399 20518802 18674790 17217161 20132043 19632207 18457598 16723640 11836018
MESH:D009765 Obesity pirinixic acid 4.0220558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 18.5312819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 18.5316049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 18.536482804 4026338
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 18.5314694615
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.5417160924
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.583988306
MESH:D010024 Osteoporosis Genistein 6.6919401787
MESH:D010024 Osteoporosis Isoflavones 6.6916562857
MESH:D015663 Osteoporosis, Postmenopausal Genistein 8.8216169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 8.8219495926
MESH:D010051 Ovarian Neoplasms arsenic trioxide 13.3619769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Cisplatin 13.366897625 15464296 19769630 17225452
MESH:D010051 Ovarian Neoplasms Estradiol 13.3619401270
MESH:D010051 Ovarian Neoplasms Genistein 13.3619005980
MESH:D010051 Ovarian Neoplasms Quercetin 13.3619005980
MESH:D010146 Pain Acetaminophen 2.0616870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 18.2815580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 18.2819003803
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 18.2816540662
MESH:D010190 Pancreatic Neoplasms Ethanol 18.2812384795
MESH:D010190 Pancreatic Neoplasms Fluorouracil 18.2815113037 16500647 19003803 16929163
MESH:D010190 Pancreatic Neoplasms Quercetin 18.2816965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2911578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.077296757
MESH:D010235 Paraganglioma arsenic trioxide 3.7619927285
MESH:D010300 Parkinson Disease Eugenol 4.2317329831
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8112520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.9015464296
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.036228378
MESH:D010997 Pleural Neoplasms Cisplatin 4.9017638057
MESH:D017499 Porokeratosis alitretinoin 5.5616144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1518163543
MESH:D011230 Precancerous Conditions Cyclosporine 13.2312371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 13.232563599
MESH:D011230 Precancerous Conditions Quercetin 13.2319056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.7611896295 11222880 11399792 11118676
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5020887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0319131511
MESH:D011471 Prostatic Neoplasms Estradiol 2.0316740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.0318626508 19082440
MESH:D011471 Prostatic Neoplasms Genistein 2.0315256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms Isoflavones 2.0316365062 17571952 17374662 17219775
MESH:D011471 Prostatic Neoplasms methylselenic acid 2.0316205645
MESH:D011471 Prostatic Neoplasms Quercetin 2.0317292933 14715546
MESH:D011537 Pruritus Ethinyl Estradiol 2.8916919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.0716882103
MESH:D012004 Rectal Neoplasms Fluorouracil 3.6516160472 15538739 18722050 18286688
MESH:D051437 Renal Insufficiency Cisplatin 3.9915464296
MESH:D015427 Reperfusion Injury pirinixic acid 2.1719058328
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 4.1312210543
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4318990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.053692021
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.9916646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 8.9914601052
MESH:D012554 Schistosomiasis japonica Quercetin 5.1116862918
MESH:D012640 Seizures 2,4-dinitrotoluene 8.1618551238
MESH:D012640 Seizures 2,6-dinitrotoluene 8.1618551238
MESH:D012640 Seizures Ethanol 8.169754883
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 1.8416192470
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.9015464296
MESH:D013088 Spermatocele Ethinyl Estradiol 3.5016709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 7.6017007042
MESH:D013274 Stomach Neoplasms Cisplatin 7.6017522103 15958060 18396642
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.6018456281
MESH:D013274 Stomach Neoplasms Ethanol 7.6018456281
MESH:D013274 Stomach Neoplasms Fluorouracil 7.6016424979 17172411 17522103 18396642 17498489 18567086 19084572 16951190 19015929 15786421
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 7.6012958204 17575124
MESH:D013276 Stomach Ulcer Acetylcysteine 10.2517918041
MESH:D013276 Stomach Ulcer Ethanol 10.2511906479 9211565 17918041 16755016 17189318 9562338
MESH:D013276 Stomach Ulcer Eugenol 10.2518543354
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.889754883
MESH:D013736 Testicular Neoplasms Cisplatin 4.2317225452 15464296
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7915669648
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 4.7315790496
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4612697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 10.067505956 3712494 6587162 6582329 1399818
MESH:D013964 Thyroid Neoplasms arsenic trioxide 10.0619014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 10.067505956
MESH:D013978 Tibial Fractures Estradiol 4.2519048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.6216280240
MESH:D016171 Torsades de Pointes arsenic trioxide 3.5315213294
MESH:D014376 Tuberculosis Rifampin 4.4915236969 18397238
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 17.4816049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 17.4816049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 17.488074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 17.4820435036 11780464 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 17.4812973940 15464296 17225452
MESH:D001749 Urinary Bladder Neoplasms Quercetin 17.4816720314
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 10.5510091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 10.5510091137
MESH:D014581 Urticaria Acetaminophen 2.5810982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 8.4116803524
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 8.4116803524
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8914692618
MESH:D014605 Uveitis Cyclosporine 3.541336536
MESH:D014625 Vaginal Neoplasms Cisplatin 4.1915577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1512125929
MESH:D014689 Venous Insufficiency coumarin 5.3412708602
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1515869587 14671159
MESH:D014839 Vomiting Cisplatin 4.2811897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8115886252
MESH:D015430 Weight Gain Dietary Fats 3.3816723640
MESH:D014985 Xerophthalmia Cyclosporine 4.0017120751
Pathway ID Pathway Name
KEGG:00520 Amino sugar and nucleotide sugar metabolism
KEGG:00053 Ascorbate and aldarate metabolism
REACT:13433 Biological oxidations
KEGG:01100 Metabolic pathways
KEGG:00040 Pentose and glucuronate interconversions
KEGG:00500 Starch and sucrose metabolism
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA37170
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00157 - NADH Dietary supplement;Micronutrient
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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