AutismKB 2.0

Annotation Detail for UQCRFS1


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Basic Information Top
Gene Symbol:UQCRFS1 ( RIP1,RIS1,RISP,UQCR5 )
Gene Full Name: ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
Band: 19q12
Quick LinksEntrez ID:7386; OMIM: 191327; Uniprot ID:UCRI_HUMAN; ENSEMBL ID: ENSG00000169021; HGNC ID: 12587
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05016Huntington's disease
hsa05010Alzheimer's disease
hsa05012Parkinson's disease
hsa00190Oxidative phosphorylation
hsa01100Metabolic pathways
hsa04260Cardiac muscle contraction
Pathway IDPathway Name
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncou
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of UQCRFS1 mRNAaffects expression 16483693
D020122 tert-Butylhydroperoxide Cyclosporine inhibits the reaction [[tert-Butylhydroperoxide co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein]affects cotreatment|decreases phosphorylation|decreases reaction 16023995
D020122 tert-Butylhydroperoxide [tert-Butylhydroperoxide co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 proteinaffects cotreatment|decreases phosphorylation 16023995
D002122 Calcium Chloride Calcium Chloride results in decreased phosphorylation of UQCRFS1 proteindecreases phosphorylation 16023995
D002122 Calcium Chloride Cyclosporine inhibits the reaction [[oxophenylarsine co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein]affects cotreatment|decreases phosphorylation|decreases reaction 16023995
D002122 Calcium Chloride Cyclosporine inhibits the reaction [[tert-Butylhydroperoxide co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein]affects cotreatment|decreases phosphorylation|decreases reaction 16023995
D002122 Calcium Chloride [oxophenylarsine co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 proteinaffects cotreatment|decreases phosphorylation 16023995
D002122 Calcium Chloride [tert-Butylhydroperoxide co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 proteinaffects cotreatment|decreases phosphorylation 16023995
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of UQCRFS1 mRNAaffects cotreatment|affects expression 17602206
D016572 Cyclosporine Cyclosporine inhibits the reaction [[oxophenylarsine co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein]affects cotreatment|decreases phosphorylation|decreases reaction 16023995
D016572 Cyclosporine Cyclosporine inhibits the reaction [[tert-Butylhydroperoxide co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein]affects cotreatment|decreases phosphorylation|decreases reaction 16023995
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of UQCRFS1 mRNAaffects cotreatment|affects expression 17602206
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of UQCRFS1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of UQCRFS1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UQCRFS1 mRNAaffects cotreatment|increases expression 17942748
D007657 Ketone Bodies Ketone Bodies results in increased expression of UQCRFS1 mRNAincreases expression 16807920
C029341 oxophenylarsine Cyclosporine inhibits the reaction [[oxophenylarsine co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein]affects cotreatment|decreases phosphorylation|decreases reaction 16023995
C029341 oxophenylarsine [oxophenylarsine co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 proteinaffects cotreatment|decreases phosphorylation 16023995
D010100 Oxygen UQCRFS1 protein affects the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]affects reaction|increases expression 18353899
D013629 Tamoxifen Tamoxifen affects the expression of UQCRFS1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UQCRFS1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of UQCRFS1 mRNAincreases expression 20399798
C066340 tolcapone tolcapone binds to UQCRFS1 proteinaffects binding 19783845
D014212 Tretinoin [IFNB1 protein co-treated with Tretinoin] results in increased expression of UQCRFS1 proteinaffects cotreatment|increases expression 16826196
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6414745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.9315322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.6418287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0417505938
MESH:D055371 Acute Lung Injury Oxygen 4.5916759491
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8214692618
MESH:D000236 Adenoma Diethylnitrosamine 2.886695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 10.3317162532 19061943 18056438 16434500 17620307 19052882
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.3316835633
MESH:D017109 Akathisia, Drug-Induced tolcapone 6.3911080934
MESH:D000505 Alopecia Tretinoin 3.6615955085
MESH:D000544 Alzheimer Disease tolcapone 3.2920150427
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0011748828
MESH:D000860 Anoxia Oxygen 5.1420872349
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.3115885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.3116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2716292516
MESH:D001249 Asthma Tretinoin 2.3616456186
MESH:D050197 Atherosclerosis Oxygen 3.8316391483
MESH:D001471 Barrett Esophagus Tretinoin 4.4716935849
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.1212125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.1216197459 16206674
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8015746008
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.3617474063
MESH:D001943 Breast Neoplasms Oxygen 2.3617263869
MESH:D001943 Breast Neoplasms Tamoxifen 2.3616818667 16202921 19084267 11161223 15668708 16273361 17440819 18351453 19221464 19142967 19066611 19155303 19487384 20135344 19011961 19103187 19200415 19059307 17049068 18855134 20544844 18629630 19189212 17261762 19288272 19115204 18821012 18997820 20065188 19189210 21138602 20859285 18815881 21152245 18984771 19289846 20390343 17242785 19410462 17893378 15565566 16873071 18425577 19244106 20005174
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3620435547
MESH:D001943 Breast Neoplasms Tretinoin 2.3616443354 16873071 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.6716813970
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8416835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5819066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2616168501
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 4.6418210153 19919837 19519916 17162532 19701751 19383236 16807293 16830150 19052882 18691550 18785209 20514400 17428255 16502159 19335982 20727157 20935162 16328049 20524982 18665156 21159647 10672840 19822196 16288022 3581430 19208518 18393292 17173139 19394651 19539802 20007298 18971187 3084413 11831363 20084675 16540662 18506893 18494052 19171122 10737359 18056438 17138121 18978308 16935385 20101231 20432363 16779866 19107877 17978847 17055752 16681979 16569478 16698587 16878318 20214788 17761372 20512989 19418558 18788625
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 4.6416924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 4.641917145
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.3016051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6617572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3918670907 18850075 16120746
MESH:D002386 Cataract Tretinoin 3.1217460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.7312371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.732727394 21159647 17174075 7505956
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.6716129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.4919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.4916835633
MESH:D002779 Cholestasis Cyclosporine 7.9119486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.9117333356 16105132 11677210 16919318 17681005 15861022 17110522
MESH:D002822 Choriocarcinoma Tretinoin 5.2616461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.8315340226 12621046 15668235 8697196 16354765
MESH:D002972 Cleft Palate Tretinoin 5.839407595
MESH:D003092 Colitis Tretinoin 3.7817035595
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1114669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4610048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.469224671 10589399 9142499 9664655 9211117 9125849 16925845 17551590 14991402 8800419
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4319031437
MESH:D003866 Depressive Disorder tolcapone 4.3411224284 7768276
MESH:D003865 Depressive Disorder, Major tolcapone 4.9510440460
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.2620387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2617107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.5219279558
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 6.4419107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.4420420201
MESH:D056486 Drug-Induced Liver Injury tolcapone 6.4419783845 16604736
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8011462148
MESH:D004409 Dyskinesia, Drug-Induced tolcapone 5.5011455177
MESH:D004417 Dyspnea Oxygen 4.9320016425
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.4311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.2716714409 18230668 15322242
MESH:D004489 Edema, Cardiac Tretinoin 12.2718230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.1612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.1619031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.5517893378 16202921 20544844 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 7.5516569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.079294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.2116302075
MESH:D054908 Extensively Drug-Resistant Tuberculosis tolcapone 6.0419578428
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.9711564622
MESH:D005124 Eye Abnormalities Tretinoin 8.979664655 16938888
MESH:D005234 Fatty Liver Cyclosporine 19.2319224547
MESH:D005234 Fatty Liver Diethylnitrosamine 19.2321071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 19.2315345470
MESH:D005234 Fatty Liver Tamoxifen 19.2314986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2716709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5311858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.6114745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2619069698
MESH:D005355 Fibrosis Cyclosporine 15.1612639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.1620067830
MESH:D005355 Fibrosis Tretinoin 15.1617994277
MESH:D005739 Gas Poisoning Oxygen 5.3120016425
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.308708960
MESH:D005909 Glioblastoma Tretinoin 3.0417312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6910696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2216096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2616084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.6211294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 6.629664655 14991402
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.5015720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3911000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.9612621046 16120746 15340226
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1416959395 15340226 8697196 16354765 18606429
MESH:D006930 Hyperalgesia Tretinoin 3.2516870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6416778211
MESH:D006973 Hypertension Cyclosporine 5.0110903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.0118670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8816945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5217937319
MESH:D007249 Inflammation Diethylnitrosamine 8.4318785209
MESH:D007249 Inflammation Tamoxifen 8.4319457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.4312878042 12200463
MESH:D007410 Intestinal Diseases Tretinoin 3.8417994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.1216580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.1215992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5415604871
MESH:D007674 Kidney Diseases Cyclosporine 2.378314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 7.4512371664
MESH:D007680 Kidney Neoplasms Tamoxifen 7.4518625569
MESH:D007938 Leukemia Tretinoin 2.7917143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.7516482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0819850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1919642359 16788101 17339181 16766008 9834237 15748426 17217047 16140955 19035177 19029980 17107899 17301526 17712046 16331271 17368321 16935935 12679006 17649720 16823087 19225113 19075265 17361223 17506722 16891316 17294898
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.349224671
MESH:D008064 Lipidoses Tamoxifen 3.1915342952 17567588
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.8520032147 18522880 19638242 18665156 18407596
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.4818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4812878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 3.4818397230 16248980
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1117034775
MESH:D008113 Liver Neoplasms Clofibric Acid 10.8817602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 10.882862719 19426721 20101389 18754104 20137499 19256749 19294768 20405173 12112319 19427195 12771043 18644402 18648771 10737359 21071580 9163691 20452335 19833225 19812893 21047994 21278145 16942905 21167192 20492335 19073162 20118626 15885732 19690152 19850985 20434301 15175105 20583210 19638242 18978307 19499222 19996281 19642983 19090486 18977376 19551842 19254457 2422723 19255062 20501860
MESH:D008113 Liver Neoplasms Tamoxifen 10.8816684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.8816984957
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 5.8718164116 18775883 18093689 19519916 17942915 18282651 3124819 19004024 18253720 18544905 19126423 17174075 9362446 19009564 21159647 18308698 16842330 18079962 2563599 17854601 19539802 16267830
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.8712151625
MESH:D055370 Lung Injury Oxygen 4.5818339021
MESH:D008175 Lung Neoplasms Diethylnitrosamine 3.4020512841 20970405 21163286 6695378
MESH:D008175 Lung Neoplasms Tamoxifen 3.4018625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.4019555203 11884234
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8419428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.6614580682 11731420 19196722 16827153 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.6419453300
MESH:D008527 Medulloblastoma Tretinoin 2.8017453147
MESH:D008545 Melanoma Tamoxifen 3.3112393984 19393235
MESH:D008545 Melanoma Tretinoin 3.3116752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2615990972
MESH:D008591 Meningomyelocele Tretinoin 4.5016940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8816801185
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.1117596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0612213967
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.809029167 3581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.8019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5319410462
MESH:D009369 Neoplasms Tretinoin 2.4316946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.1019189210 19200415 19196722
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3319348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.7314600291
MESH:D009421 Nervous System Malformations Tretinoin 9.739125849
MESH:D009436 Neural Tube Defects Tretinoin 3.099142499
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.3920387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.2120387270
MESH:D010051 Ovarian Neoplasms Tretinoin 2.3616936753
MESH:D010146 Pain Tretinoin 2.9516870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.3116540662
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.3115976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7511578682
MESH:D010300 Parkinson Disease tolcapone 3.6111793426 7566641 9305320 11432539 9708959 11746615 9591521 8635184 17089403 1977408 20216409 19578428 10651109 9754991 9333106 18328768 16758261 8739811 19783845 20334432 11586115
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3512520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6218163543
MESH:D011230 Precancerous Conditions Cyclosporine 9.1012371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 9.102563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2711399792 11118676 11222880 11896295
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.1415067354
MESH:D011507 Proteinuria Tretinoin 3.6616636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.3916919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.2416882103
MESH:D011625 Pterygium Tretinoin 4.8816723453
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 4.5717627322 18339021
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9018990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1616283617 16116481
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 9.578532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.5716192470
MESH:D012878 Skin Neoplasms Tretinoin 9.5716467112
MESH:D013088 Spermatocele Ethinyl Estradiol 11.8916709447
MESH:D013088 Spermatocele Tamoxifen 11.8916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.1219457130
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.4318456281
MESH:D013274 Stomach Neoplasms Tretinoin 2.4317261132
MESH:D013398 Sudden Infant Death Oxygen 5.6312563064
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2015669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0012697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.317505956
MESH:D013964 Thyroid Neoplasms Tretinoin 7.3116026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.8416051514
MESH:D014376 Tuberculosis Tretinoin 3.2616040207
MESH:D018088 Tuberculosis, Multidrug-Resistant tolcapone 6.0419578428
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 2.378653321 17572228 16712894
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.7316129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3614692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.7116752155
MESH:D014605 Uveitis Cyclosporine 4.081336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6912125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5914671159 15869587
MESH:D014820 Vitiligo tolcapone 11.3110573327
MESH:D014820 Vitiligo Tretinoin 11.3116761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3515886252
MESH:D009396 Wilms Tumor Tretinoin 4.0216287080
MESH:D014985 Xerophthalmia Cyclosporine 4.5417120751
Pathway ID Pathway Name
KEGG:05010 Alzheimer's disease
KEGG:04260 Cardiac muscle contraction
KEGG:05016 Huntington's disease
KEGG:01100 Metabolic pathways
KEGG:00190 Oxidative phosphorylation
KEGG:05012 Parkinson's disease
REACT:6305 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB03122 - B-Octylglucoside Detergents
DB04141 - 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
DB04799 - 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole
DB07401 - METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE
DB07636 - 5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONE
DB07763 - (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
DB07778 - FAMOXADONE
DB08330 - METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
DB08453 - 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE
DB08690 - UBIQUINONE-2
No data
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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