AutismKB 2.0

Annotation Detail for USF2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:USF2 ( FIP,bHLHb12 )
Gene Full Name: upstream transcription factor 2, c-fos interacting
Band: 19q13
Quick LinksEntrez ID:7392; OMIM: 600390; Uniprot ID:USF2_HUMAN; ENSEMBL ID: ENSG00000105698; HGNC ID: 12594
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
No data
Pathway IDPathway Name
200044Validated transcriptional targets of AP1 family members Fra1 and Fra2
Pathway IDPathway Name
P00047PDGF signaling pathway
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
Alzheimer's disease
NEUROLOGICAL
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of USF2 mRNAaffects expression 16483693
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in increased expression of USF2 mRNAincreases expression 17553608
D005947 Glucose Glucose results in increased activity of USF2 proteinincreases activity 15767253
D012643 Selenium [Selenium co-treated with Vitamin E] results in increased expression of USF2 mRNAaffects cotreatment|increases expression 19244175
D012643 Selenium Selenium results in increased expression of USF2 mRNAincreases expression 19244175
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in increased expression of USF2 mRNAaffects cotreatment|increases expression 19244175
D014810 Vitamin E Vitamin E results in increased expression of USF2 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1018287403
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.4116050911
MESH:D003092 Colitis Selenium 4.2617936198
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D056486 Drug-Induced Liver Injury Selenium 2.2515131321
MESH:C538011 Eales disease Vitamin E 5.329068938
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1516080930
MESH:D006333 Heart Failure Selenium 3.2717162251
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8016863852 16490937
MESH:D019584 Hot Flashes Vitamin E 4.5814716179
MESH:D007251 Influenza, Human Selenium 13.0916624496
MESH:D007251 Influenza, Human Vitamin E 13.0916624496
MESH:D007674 Kidney Diseases Vitamin E 2.9812488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.2616518626
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9016169303
MESH:D008171 Lung Diseases Vitamin E 3.4016863852
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.9715318939
MESH:D008545 Melanoma Glucose 3.1114993021
MESH:D008654 Mesothelioma Selenium 2.9015107826
MESH:D010954 Plasmacytoma Selenium 5.5015087411
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2515084515
MESH:D012871 Skin Diseases Vitamin E 2.5118709164
MESH:D012878 Skin Neoplasms Glucose 3.8714993021
MESH:D020521 Stroke Vitamin E 3.8116517955
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA37224
    • No data
    No data
    Releated drug ID Related drug Name
    PA449748gemcitabine
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved