Annotation Detail for USH2A
Basic Information Top
| Gene Symbol: | USH2A ( RP39,US2,USH2,dJ1111A8.1 ) |
|---|---|
| Gene Full Name: | Usher syndrome 2A (autosomal recessive, mild) |
| Band: | 1q41 |
| Quick Links | Entrez ID:7399; OMIM: 608400; Uniprot ID:USH2A_HUMAN; ENSEMBL ID: ENSG00000042781; HGNC ID: 12601 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| No data |
| No data |
| Desease Name |
|---|
| CHEMDEPENDENCY |
| smoking cessation |
| No data |
| Desease Name |
|---|
| Usher syndrome, type 2A |
| Retinitis pigmentosa-39 |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of USH2A mRNA | affects expression | 16483693 |
| D005472 | Fluorouracil | TP53 protein affects the reaction [Fluorouracil results in decreased expression of USH2A mRNA] | affects reaction|decreases expression | 15016801 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000138 | Acidosis | Ammonium Chloride | 4.44 | 18287403 | |
| MESH:D000230 | Adenocarcinoma | Fluorouracil | 2.51 | 17638652 | |
| MESH:D000740 | Anemia | Fluorouracil | 4.22 | 17963324 16511603 15504547 | |
| MESH:D001943 | Breast Neoplasms | Fluorouracil | 2.42 | 19217205 18608205 15136595 18357371 16595493 16557594 16110121 | |
| MESH:D002276 | Carcinoid Tumor | Fluorouracil | 5.74 | 16051944 | |
| MESH:D002277 | Carcinoma | Fluorouracil | 3.97 | 17121937 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Fluorouracil | 2.12 | 17971768 17045692 17088986 18930000 16799960 16332177 | |
| MESH:D002292 | Carcinoma, Renal Cell | Fluorouracil | 3.20 | 18695887 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Fluorouracil | 2.59 | 16757204 18986760 17066447 16280240 | |
| MESH:D003110 | Colonic Neoplasms | Fluorouracil | 2.29 | 17172411 17725105 17287894 18772588 16510598 17018589 17169374 15001691 17016597 16340194 | |
| MESH:D015179 | Colorectal Neoplasms | Fluorouracil | 2.01 | 15148649 17594712 15289873 14970324 16303861 18802399 18509181 16391804 17454858 16331619 18383874 16282729 17401013 17695437 16524972 17094418 18288408 20501625 17016601 17255274 18448328 18949393 | |
| MESH:D007644 | Darier Disease | Fluorouracil | 5.68 | 16733453 | |
| MESH:D004938 | Esophageal Neoplasms | Fluorouracil | 2.54 | 15173087 16337965 16481741 17638652 16785472 | |
| MESH:D005910 | Glioma | Fluorouracil | 3.02 | 16145905 | |
| MESH:D006258 | Head and Neck Neoplasms | Fluorouracil | 3.70 | 15162350 18337622 15102660 | |
| MESH:D007680 | Kidney Neoplasms | Fluorouracil | 3.74 | 16985049 | |
| MESH:D008113 | Liver Neoplasms | Fluorouracil | 2.62 | 18383874 15113037 16603448 17045692 | |
| MESH:D008175 | Lung Neoplasms | Fluorouracil | 2.01 | 15246190 | |
| MESH:D008178 | Lupus Erythematosus, Cutaneous | Fluorouracil | 5.68 | 15086387 | |
| MESH:D009062 | Mouth Neoplasms | Fluorouracil | 4.02 | 16757204 18986760 | |
| MESH:D009369 | Neoplasms | Fluorouracil | 2.80 | 18600527 16928823 18239605 | |
| MESH:D020258 | Neurotoxicity Syndromes | Fluorouracil | 3.75 | 16436463 | |
| MESH:D010190 | Pancreatic Neoplasms | Fluorouracil | 2.79 | 19003803 15113037 16500647 16929163 | |
| MESH:D011471 | Prostatic Neoplasms | Fluorouracil | 3.34 | 19082440 18626508 | |
| MESH:D012004 | Rectal Neoplasms | Fluorouracil | 4.48 | 15538739 18722050 18286688 16160472 | |
| MESH:D012174 | Retinitis Pigmentosa | marker/mechanism | |||
| MESH:D013274 | Stomach Neoplasms | Fluorouracil | 2.00 | 16424979 16951190 17522103 19015929 18567086 17172411 15786421 19084572 17498489 18396642 | |
| MESH:D014062 | Tongue Neoplasms | Fluorouracil | 4.50 | 16280240 | |
| MESH:D052245 | Usher Syndromes | marker/mechanism | |||
| OMIM:276901 | USHER SYNDROME, TYPE IIA | marker/mechanism | |||
| MESH:D002583 | Uterine Cervical Neoplasms | Fluorouracil | 4.38 | 16803524 |
| No data |