AutismKB 2.0

Annotation Detail for WNT5A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:WNT5A ( hWNT5A )
Gene Full Name: wingless-type MMTV integration site family, member 5A
Band: 3p14.3
Quick LinksEntrez ID:7474; OMIM: 164975; Uniprot ID:WNT5A_HUMAN; ENSEMBL ID: ENSG00000114251; HGNC ID: 12784
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04916Melanogenesis
hsa04310Wnt signaling pathway
hsa04340Hedgehog signaling pathway
hsa05217Basal cell carcinoma
hsa05200Pathways in cancer
Pathway IDPathway Name
Signaling by GPCR
Pathway IDPathway Name
200171Validated targets of C-MYC transcriptional repression
200016Noncanonical Wnt signaling pathway
200055Wnt signaling network
Pathway IDPathway Name
P00005Angiogenesis
P00004Alzheimer disease-presenilin pathway
P00012Cadherin signaling pathway
P00057Wnt signaling pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
2111Systemic infection
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D006710 Homocysteine Homocysteine results in decreased expression of WNT5A mRNAdecreases expression 17320366
D000643 Ammonium Chloride Ammonium Chloride affects the expression of WNT5A mRNAaffects expression 16483693
D001152 Arsenicals Arsenicals affects the acetylation of WNT5A promoteraffects acetylation 19061910
C015001 arsenite arsenite results in increased expression of WNT5A mRNAincreases expression 19061910
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of WNT5A mRNAincreases expression 20064835
C006780 bisphenol A bisphenol A results in decreased expression of WNT5A mRNAdecreases expression 16029874
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of WNT5A mRNAincreases expression 16780995
D004390 Chlorpyrifos Chlorpyrifos results in decreased expression of WNT5A mRNAdecreases expression 18502319
D016572 Cyclosporine Cyclosporine results in decreased expression of WNT5A mRNAdecreases expression 20106945
D003976 Diazinon Diazinon affects the expression of WNT5A mRNAaffects expression 18502319
D003976 Diazinon Diazinon results in decreased expression of WNT5A mRNAdecreases expression 19130878
D004026 Dieldrin Dieldrin results in decreased expression of WNT5A mRNAdecreases expression 19130878
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of WNT5A mRNAincreases expression 15070830
15073149
D004054 Diethylstilbestrol WNT5A protein affects the reaction [Diethylstilbestrol results in decreased expression of HOXA10 mRNA]affects reaction|decreases expression 15073149
D004054 Diethylstilbestrol WNT5A protein affects the reaction [Diethylstilbestrol results in decreased expression of HOXA11 mRNA]affects reaction|decreases expression 15073149
D004054 Diethylstilbestrol WNT5A protein affects the reaction [Diethylstilbestrol results in decreased expression of WNT7A mRNA]affects reaction|decreases expression 15073149
D002117 Calcitriol Calcitriol results in increased expression of WNT5A mRNAincreases expression 16002434
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of WNT5A mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in increased expression of WNT5A mRNAincreases expression 19619570
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of WNT5A mRNAaffects expression 16551644
D005492 Folic Acid Folic Acid affects the expression of WNT5A mRNAaffects expression 17320366
C056507 gemcitabine gemcitabine results in decreased expression of WNT5A mRNAdecreases expression 17039268
D019833 Genistein Genistein results in decreased expression of WNT5A mRNAdecreases expression 17341692
C010176 halofuginone halofuginone results in increased expression of WNT5A mRNAincreases expression 17180598
D008727 Methotrexate Methotrexate results in increased expression of WNT5A mRNAincreases expression 17320366
D008770 Methylnitrosourea Methylnitrosourea results in increased expression of WNT5A mRNAincreases expression 17341692
D015735 Mifepristone Mifepristone results in increased expression of WNT5A mRNAincreases expression 17584828
D016685 Mitomycin WNT5A protein affects the susceptibility to Mitomycinaffects response to substance 16217747
C406082 monomethylarsonous acid monomethylarsonous acid results in increased expression of WNT5A mRNAincreases expression 19061910
D009532 Nickel Nickel results in increased expression of WNT5A mRNAincreases expression 19130878
D010634 Phenobarbital NR1I3 protein promotes the reaction [Phenobarbital results in increased expression of WNT5A mRNA]increases expression|increases reaction 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of WNT5A mRNAincreases expression 19482888
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of WNT5A mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of WNT5A mRNAincreases expression 18301758
C025299 polyphenols polyphenols results in decreased expression of WNT5A mRNAdecreases expression 16293270
D020849 Raloxifene [Raloxifene co-treated with ESR2 protein] results in decreased expression of WNT5A mRNAaffects cotreatment|decreases expression 19059307
C017947 sodium arsenite sodium arsenite results in decreased expression of WNT5A mRNAdecreases expression 12679051
D013629 Tamoxifen [Tamoxifen co-treated with ESR2 protein] results in decreased expression of WNT5A mRNAaffects cotreatment|decreases expression 19059307
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of WNT5A mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of WNT5A mRNAdecreases expression 20106945
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of WNT5A mRNAincreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of WNT5A mRNAincreases expression 20067830
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of WNT5A mRNAdecreases expression 19933214
17586704
D014212 Tretinoin Tretinoin results in decreased expression of WNT5A mRNAdecreases expression 16604517
D014415 Tunicamycin Tunicamycin results in increased expression of WNT5A mRNAincreases expression 17127020
C113580 U 0126 U 0126 results in increased expression of WNT5A mRNAincreases expression 17320366
D002762 Cholecalciferol Cholecalciferol results in increased expression of WNT5A mRNAincreases expression 17170073
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1714745880
MESH:D000014 Abnormalities, Drug-Induced Methotrexate 12.1712039119
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 12.176195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 12.1715322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.1918287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5717505938
MESH:D000168 Acrocephalosyndactylia U 0126 5.1117694057
MESH:D058186 Acute Kidney Injury Folic Acid 4.0017003819 16316344 16595132
MESH:D055371 Acute Lung Injury Nickel 8.1216166738
MESH:D055371 Acute Lung Injury pirinixic acid 8.1218653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 12.4420127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 12.4411473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.4414692618
MESH:D000230 Adenocarcinoma Genistein 12.4411473722
MESH:D000230 Adenocarcinoma Methylnitrosourea 12.4415688392 15113128
MESH:D000236 Adenoma Benzo(a)pyrene 6.266695378
MESH:D000236 Adenoma Folic Acid 6.2616963246
MESH:D018248 Adenoma, Liver Cell Phenobarbital 15.1517620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.1516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.1516835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3215276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5316712894 17306315
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 7.9611874814 16611668 17119214
MESH:D000382 Agricultural Workers' Diseases Diazinon 7.9616487989
MESH:D000419 Albuminuria Raloxifene 4.2517451421 17308373
MESH:D000505 Alopecia Tretinoin 3.3315955085
MESH:D000544 Alzheimer Disease Folic Acid 4.2817116317
MESH:D000544 Alzheimer Disease Raloxifene 4.2815800139
MESH:D000686 Amyloidosis Diethylstilbestrol 4.1315469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6311748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7119183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.4415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.4416412693
MESH:D001172 Arthritis, Rheumatoid Methotrexate 4.5417286800
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.5416292516
MESH:D001249 Asthma Tretinoin 2.2316456186
MESH:D001321 Autistic Disorder Folic Acid 2.7621388746
MESH:D001321 Autistic Disorder Homocysteine 2.7620468076 16297937
MESH:D001327 Autoimmune Diseases Cholecalciferol 4.6716142846
MESH:D001471 Barrett Esophagus Tretinoin 4.0516935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.3719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.3712125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 13.3716206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5315746008
MESH:D001862 Bone Resorption bisphenol A 3.5411985600
MESH:D001930 Brain Injuries Raloxifene 4.1216580743
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 15.2720146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 15.2717123778
MESH:D001943 Breast Neoplasms Calcitriol 15.2711237771
MESH:D001943 Breast Neoplasms Dieldrin 15.2711859874 15770527
MESH:D001943 Breast Neoplasms Diethylstilbestrol 15.2717129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 15.2717289903 17018787 16675129 17261762 18497071 19861407 14630087 12948864
MESH:D001943 Breast Neoplasms Folic Acid 15.2716777985
MESH:D001943 Breast Neoplasms gemcitabine 15.2718382427 17039268
MESH:D001943 Breast Neoplasms Genistein 15.2716873071 16541309 17200150
MESH:D001943 Breast Neoplasms Methotrexate 15.2716978400
MESH:D001943 Breast Neoplasms Methylnitrosourea 15.2716253758 14633655 11306469
MESH:D001943 Breast Neoplasms Nickel 15.2715986119
MESH:D001943 Breast Neoplasms Raloxifene 15.2717242785 15572757 16912660 15758505 17595753 17893378 16837676 17952589 17049068 17440819 17261762 15775269
MESH:D001943 Breast Neoplasms Tamoxifen 15.2711161223 19115204 20005174 17440819 16202921 18815881 19289846 19066611 18425577 17049068 18984771 20859285 18629630 21152245 17242785 19084267 20135344 19487384 18855134 19189210 19155303 19288272 18351453 19011961 19142967 19221464 18821012 18997820 16273361 15668708 17261762 21138602 17893378 20390343 20544844 19059307 20065188 19410462 19200415 19189212 16873071 19244106 16818667 15565566 19103187
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 15.2720435547
MESH:D001943 Breast Neoplasms Tretinoin 15.2716166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2216813970
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0916111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4216097048 16124888 15700767 16011737 16227642 3786805 10355542 15721981 18705752 15673190 16192424 16050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5116835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1519066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.7816168501
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 15.7218788625
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 15.7215948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Estradiol 15.7216924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 15.7216924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 15.726705139 17173139 20935162 1701930 20007298
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 15.7216507464 15276417 17306315
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 15.7216924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 15.721917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.6217123778
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 9.8220419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 9.8211237771
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 9.8218572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 9.8216051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 8.4417572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.4417572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.1618850075 16120746 18670907
MESH:D002318 Cardiovascular Diseases Folic Acid 10.8416755160
MESH:D002318 Cardiovascular Diseases Genistein 10.8416332659
MESH:D002318 Cardiovascular Diseases Raloxifene 10.8415775269
MESH:D002386 Cataract Methylnitrosourea 7.0112484553
MESH:D002386 Cataract Tretinoin 7.0117460283
MESH:D002471 Cell Transformation, Neoplastic marker/mechanism 19061910
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 18.4312371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 18.4318566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 18.437505956 2727394
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 18.4319716837
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 18.4319524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.894080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2216129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8516835633
MESH:D002779 Cholestasis Cyclosporine 11.7719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.7715861022 17333356 17110522 16919318 17681005 11677210 16105132
MESH:D002779 Cholestasis pirinixic acid 11.7719176532
MESH:D002822 Choriocarcinoma Tretinoin 4.7816461808
MESH:D002971 Cleft Lip Folic Acid 3.7821254359
MESH:D002972 Cleft Palate Folic Acid 8.9521254359 8946559
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 8.9515340226 15668235 12621046 8697196 16354765
MESH:D002972 Cleft Palate Tretinoin 8.959407595
MESH:D003072 Cognition Disorders Raloxifene 4.2615800139
MESH:D003092 Colitis Tretinoin 3.3517035595
MESH:D003110 Colonic Neoplasms arsenite 5.5115037631
MESH:D003110 Colonic Neoplasms Genistein 5.5117182828
MESH:D003110 Colonic Neoplasms polyphenols 5.5116293270
MESH:D015179 Colorectal Neoplasms Folic Acid 2.6917116713 17087956 16985020 16963246 17245555
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7517141729 14669216
MESH:D003324 Coronary Artery Disease Homocysteine 3.6216379339
MESH:D019465 Craniofacial Abnormalities Methotrexate 3.619562676 12039119
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.6120055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.619224671 8800419 9211117 16925845 9142499 9125849 14991402 10589399 17551590 9664655
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.2112952375 16002989
MESH:D003550 Cystic Fibrosis Methotrexate 3.9219747007
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0019031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.8517474826
MESH:D017449 Dermatitis, Allergic Contact Nickel 3.6117100760 17244072 19470301
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2518249437
MESH:D003877 Dermatitis, Contact Nickel 4.302952479
MESH:D003882 Dermatomyositis Methotrexate 4.7820191521
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 6.6416886840
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.6416647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.6417107852
MESH:D003928 Diabetic Nephropathies Estradiol 13.2419279558
MESH:D003928 Diabetic Nephropathies Raloxifene 13.2415920148 17308373 17451421
MESH:D003928 Diabetic Nephropathies Tamoxifen 13.2419279558
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 5.5910092053 16177239 10915739 7120509 2869522 7179309 3786805 4309450 15027814 15998439 19336974 7440962 19085960 9327722 11566570 6623471 17522070 3732212 21278145 15968718 16227642 6884620
MESH:D056486 Drug-Induced Liver Injury polyphenols 5.5919370779
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.5920420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4911462148
MESH:D004417 Dyspnea Diazinon 4.4316487989
MESH:D004421 Dystonia Phenobarbital 3.671851702
MESH:D004487 Edema pirinixic acid 9.5512083418
MESH:D004487 Edema Raloxifene 9.5515860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 9.5511000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.6918230668 16714409 15322242
MESH:D004489 Edema, Cardiac Tretinoin 10.6918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 19.0715138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 19.0712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 19.0715845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 19.0719031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 10.6716402032
MESH:D004714 Endometrial Hyperplasia Genistein 10.6716402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 25.9715700306 16804899
MESH:D016889 Endometrial Neoplasms Estradiol 25.9711473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Folic Acid 25.9717301261
MESH:D016889 Endometrial Neoplasms Genistein 25.9711473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 25.9716202921 17893378 20544844 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 25.9716569247
MESH:D004715 Endometriosis Mifepristone 8.1016134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.109294722 10568697
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.753659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.5011558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.7020417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.246401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.897750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.653659116
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 1.9116530937
MESH:D017889 Exfoliation Syndrome Folic Acid 12.1616504073
MESH:D017889 Exfoliation Syndrome Homocysteine 12.1616504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.9311564622
MESH:D005124 Eye Abnormalities Tretinoin 7.939664655 16938888
MESH:D005234 Fatty Liver arsenite 31.9318296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 31.9319224547 16239168 12631006 16045604 12795759 17595544 61145 15959796
MESH:D005234 Fatty Liver Cyclosporine 31.9319224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 31.9315345470
MESH:D005234 Fatty Liver pirinixic acid 31.9320131406 19236843
MESH:D005234 Fatty Liver Raloxifene 31.9317473493
MESH:D005234 Fatty Liver Tamoxifen 31.9319224547 14986274
MESH:D052776 Female Urogenital Diseases marker/mechanism 16002989
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.4615751030 16611131 16002989 16513791 16534752
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.4616709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1011858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1614745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.8119069698
MESH:D005354 Fibrosarcoma Methylnitrosourea 4.8611555667
MESH:D005355 Fibrosis arsenite 23.9218296743
MESH:D005355 Fibrosis Carbon Tetrachloride 23.9218705752
MESH:D005355 Fibrosis Cyclosporine 23.9212168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.9220067830
MESH:D005355 Fibrosis Tretinoin 23.9217994277
MESH:D005756 Gastritis Folic Acid 4.7117171786
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 11.5916452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 11.5916452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.858708960
MESH:D005901 Glaucoma Folic Acid 10.7216504073
MESH:D005901 Glaucoma Homocysteine 10.7216504073
MESH:D005909 Glioblastoma Genistein 6.4116598420
MESH:D005909 Glioblastoma Tretinoin 6.4117312396
MESH:D005910 Glioma Methylnitrosourea 3.419825942
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2210696789
MESH:D006086 Graft vs Host Disease Methotrexate 4.7916518429
MESH:D006258 Head and Neck Neoplasms Tretinoin 2.9416096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.7816084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 18.9520471113
MESH:D006330 Heart Defects, Congenital Folic Acid 18.9517286298 16524890
MESH:D006330 Heart Defects, Congenital Homocysteine 18.9519638421
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 18.9510048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 18.959664655 14991402
MESH:D006331 Heart Diseases Raloxifene 3.2811110106
MESH:D006333 Heart Failure pirinixic acid 2.3120558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0515720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0111000095
MESH:D006505 Hepatitis Carbon Tetrachloride 8.4619110552 19900420
MESH:D006505 Hepatitis Diazinon 8.4616487989
MESH:D006529 Hepatomegaly Phenobarbital 12.3016109766
MESH:D006529 Hepatomegaly pirinixic acid 12.3019772884 19176532 18467677 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.3016120746 15340226 12621046
MESH:D006558 Herpes Genitalis Estradiol 4.6615709030
MESH:D015658 HIV Infections Nickel 3.6217263646
MESH:D006679 HIV Seropositivity Folic Acid 5.1217209195
MESH:D006689 Hodgkin Disease sodium arsenite 2.8512676792
MESH:D019584 Hot Flashes Estradiol 3.3817088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.678697196 18606429 15340226 16354765 16959395
MESH:D006930 Hyperalgesia Tretinoin 2.9316870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1616899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2116778211
MESH:D006943 Hyperglycemia pirinixic acid 2.8720558911
MESH:D020138 Hyperhomocysteinemia Folic Acid 8.8116395265 16397167 16865747 16433478 16755160
MESH:D020138 Hyperhomocysteinemia Homocysteine 8.8117292331 18234410 17369066
MESH:D006965 Hyperplasia Diethylstilbestrol 10.1212960047 14722030
MESH:D006965 Hyperplasia halofuginone 10.1211874485
MESH:D006973 Hypertension Cyclosporine 7.7110903974
MESH:D006973 Hypertension Raloxifene 7.7115787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.7118670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7315338365
MESH:D007021 Hypospadias Diethylstilbestrol 10.0516002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.0516569931 16945680
MESH:D007246 Infertility Diethylstilbestrol 4.0115036965
MESH:D007247 Infertility, Female Dieldrin 9.1610630421
MESH:D007247 Infertility, Female Ethinyl Estradiol 9.1612013081
MESH:D007248 Infertility, Male Diazinon 14.0912948887 16466525
MESH:D007248 Infertility, Male Ethinyl Estradiol 14.0917937319
MESH:D007248 Infertility, Male Methylnitrosourea 14.097193160
MESH:D007248 Infertility, Male sodium arsenite 14.0912646999 15346721
MESH:D007249 Inflammation Nickel 10.4016166738
MESH:D007249 Inflammation polyphenols 10.4016366677
MESH:D007249 Inflammation Tamoxifen 10.4019457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 10.4012878042 12200463
MESH:D007333 Insulin Resistance bisphenol A 10.9116393666
MESH:D007333 Insulin Resistance Estradiol 10.9116627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 10.9116306350
MESH:D007410 Intestinal Diseases Tretinoin 3.4117994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.8416580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.8417551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0715604871
MESH:D007674 Kidney Diseases Cyclosporine 8.808314463 18776723 10903974
MESH:D007674 Kidney Diseases Estradiol 8.8015618244
MESH:D007674 Kidney Diseases sodium arsenite 8.8020008137
MESH:D007680 Kidney Neoplasms Cyclosporine 15.3312371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 15.3314681315 15003126 16762066
MESH:D007680 Kidney Neoplasms Estradiol 15.3315610895
MESH:D007680 Kidney Neoplasms Tamoxifen 15.3318625569
MESH:D007805 Language Development Disorders Methotrexate 4.769562676
MESH:D007859 Learning Disorders Diethylstilbestrol 3.7017184923
MESH:D007889 Leiomyoma Raloxifene 4.1616973256
MESH:D007896 Leishmaniasis Arsenicals 5.6015220340
MESH:D007938 Leukemia Genistein 5.7817468513 18980019
MESH:D007938 Leukemia Tretinoin 5.7817143497
MESH:D007948 Leukemia, Monocytic, Acute U 0126 4.9416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Arsenicals 5.5115748426
MESH:D007951 Leukemia, Myeloid Tretinoin 3.3719285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0116294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.9116140955 19029980 17107899 16331271 9834237 17301526 19642359 17506722 17339181 12679006 19035177 16935935 17712046 15748426 17361223 17217047 17294898 19075265 16891316 16788101 17368321 17649720 16766008 16823087 19225113
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 7.5915526292
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.599224671
MESH:D008064 Lipidoses Tamoxifen 2.8915342952 17567588
MESH:D008103 Liver Cirrhosis arsenite 18.5818296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 18.5817174718 16943688 17334410 17157831 16239168 21278145 11408273 16221502 11903743
MESH:D008103 Liver Cirrhosis halofuginone 18.5817180598
MESH:D008103 Liver Cirrhosis Methotrexate 18.5814986274
MESH:D008103 Liver Cirrhosis Phenobarbital 18.5821047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 12.3018420326 17714472 12389079 12649538 14724832 16248980 15931870 12958196 17922224 18156304 15925388 15959796 17698563 17640975 12445418 12898905 16033810 18472094 16011737 15673190 11481614 17761835 17900296 12546737 18166357 17721639 14512876 18339082 17565644 16027843 12609069 16015684 16116963 12445421 14620537 18429990 18481824 18277467 18006644 17557913 18395095 18251166 18054572 15730626 15893842 15996030 18705752 16136751 15650968 17631135 16638106 12632514 17976157 18418968 15057751 17525996 20821823 12632512 16097048 17481882 18317297 10355542 15052691 15123356 15370692 12666154 17944888 15876570 15818738 17869086 18472332 12741479 12586293 17823541 18263696 18376398 18279442 17708605 13678700 15338365 18412020 12667390 18187930 17805973 18395914 17766677 15362042 18205269 14748882 14716496 18210741 14716833 16192424
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 12.3014659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 12.3017823541
MESH:D008106 Liver Cirrhosis, Experimental halofuginone 12.3014739098 18458672 11172339 12175628 16489207
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 12.3015474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 12.3018564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 12.3012878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 12.3016248980 18397230
MESH:D008107 Liver Diseases Carbon Tetrachloride 11.4316246199 16964402 17285989 15830285 15720792
MESH:D008107 Liver Diseases Chlorpyrifos 11.4315991261
MESH:D008107 Liver Diseases Folic Acid 11.4316877991
MESH:D008107 Liver Diseases Phenobarbital 11.4319363144
MESH:D008107 Liver Diseases polyphenols 11.4316698588
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8015123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.3716899240 14706259
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 31.2021137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 31.2019294768
MESH:D008113 Liver Neoplasms Dieldrin 31.208742319 9539021
MESH:D008113 Liver Neoplasms Diethylstilbestrol 31.2015890375 16712894
MESH:D008113 Liver Neoplasms Mitomycin 31.2015113037
MESH:D008113 Liver Neoplasms Phenobarbital 31.2015975961 8742319 21047994 19482888 19812893 19073162
MESH:D008113 Liver Neoplasms pirinixic acid 31.2015890375 16377806 20007298
MESH:D008113 Liver Neoplasms sodium arsenite 31.2016712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 31.2016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 31.2016984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 8.4612014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 8.4618308698 17172636 1399818 6150874 2563599
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 8.4612151625
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 5.1016080182
MESH:D008171 Lung Diseases sodium arsenite 2.9319095001
MESH:D017563 Lung Diseases, Interstitial Methotrexate 4.6518516814
MESH:D008175 Lung Neoplasms arsenite 7.8716809336
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 7.8720064080 20464547 18569708 20135361 18816296 18520028 6695378 17053015 20869020
MESH:D008175 Lung Neoplasms Methylnitrosourea 7.8718062963
MESH:D008175 Lung Neoplasms sodium arsenite 7.8716712894 15276417 17077188 19931552 17306315
MESH:D008175 Lung Neoplasms Tamoxifen 7.8718625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 7.8711884234 19555203
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.2317718048
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.7815166399
MESH:D008223 Lymphoma Diethylstilbestrol 11.2615700306
MESH:D008223 Lymphoma Methotrexate 11.2617352296
MESH:D008223 Lymphoma Methylnitrosourea 11.2616257854 11418001
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 4.4314633661
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.1416002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3919428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 12.3517203775 16891317 11408345 11807958
MESH:D008325 Mammary Neoplasms, Experimental Genistein 12.3514578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 12.3515313902 16051031 11751437 17131329 11807958 17020996 15688392 10838139 14999141 14633655 12931682 16827153 16619500 19196723 15113128 10767621 16944150
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 12.3519196723 11731420 19196722 14580682 16827153
MESH:D020149 Manganese Poisoning Estradiol 11.4019453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.4019453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.3316832597
MESH:D008527 Medulloblastoma Tretinoin 2.6317453147
MESH:D008545 Melanoma sodium arsenite 4.6619082730 16487513
MESH:D008545 Melanoma Tamoxifen 4.6612393984 19393235
MESH:D008545 Melanoma Tretinoin 4.6616752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.8115990972
MESH:D008591 Meningomyelocele Homocysteine 11.2216602021
MESH:D008591 Meningomyelocele Tretinoin 11.2216940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4116801185
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.1815863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.9116381670
MESH:D052016 Mucositis Methotrexate 4.9117488658
MESH:D009101 Multiple Myeloma Raloxifene 3.1816497877
MESH:D009135 Muscular Diseases pirinixic acid 3.1516239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.8717596541
MESH:D009203 Myocardial Infarction Genistein 8.6517141266
MESH:D009203 Myocardial Infarction Homocysteine 8.6517412321
MESH:D009203 Myocardial Infarction pirinixic acid 8.6519151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.5516810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.5517141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.5516411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.1117484760
MESH:D009232 Myxoma Raloxifene 5.1816343187
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.4019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3919410462
MESH:D009369 Neoplasms Benzo(a)pyrene 21.1511141357
MESH:D009369 Neoplasms Dieldrin 21.158820588
MESH:D009369 Neoplasms Diethylstilbestrol 21.1515313581
MESH:D009369 Neoplasms Methylnitrosourea 21.1515533788
MESH:D009369 Neoplasms pirinixic acid 21.1517405874
MESH:D009369 Neoplasms sodium arsenite 21.1511559025
MESH:D009369 Neoplasms Tretinoin 21.1516946489 16594593
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 8.2112696579
MESH:D009374 Neoplasms, Experimental sodium arsenite 8.2120056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.6319196722 19200415 19189210
MESH:D009389 Neovascularization, Pathologic arsenite 8.9315738583
MESH:D009389 Neovascularization, Pathologic Estradiol 8.9317289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.9818481113 19348381
MESH:D009421 Nervous System Malformations bisphenol A 33.7211399458 16427766
MESH:D009421 Nervous System Malformations Diethylstilbestrol 33.7211399458
MESH:D009421 Nervous System Malformations Estradiol 33.7216427766 11399458
MESH:D009421 Nervous System Malformations Genistein 33.7216427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 33.7214600291
MESH:D009421 Nervous System Malformations Tretinoin 33.729125849
MESH:D009436 Neural Tube Defects Folic Acid 10.8717438019
MESH:D009436 Neural Tube Defects sodium arsenite 10.8712854658
MESH:D009436 Neural Tube Defects Tretinoin 10.879142499
MESH:D009442 Neurilemmoma Methylnitrosourea 5.1211555667
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 3.9215081274
MESH:D009503 Neutropenia Folic Acid 4.1716322990
MESH:D009765 Obesity pirinixic acid 1.7220558911
MESH:D010018 Osteomalacia Phenobarbital 4.0017016548
MESH:D010024 Osteoporosis Genistein 6.5719401787
MESH:D010024 Osteoporosis Raloxifene 6.5715775268 19059307 17882678
MESH:D015663 Osteoporosis, Postmenopausal Genistein 9.0216169203
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 9.0217823083 17893378 15579764 15758505
MESH:D010049 Ovarian Diseases bisphenol A 4.6211985600
MESH:D010051 Ovarian Neoplasms Estradiol 17.2319401270
MESH:D010051 Ovarian Neoplasms Genistein 17.2319005980
MESH:D010051 Ovarian Neoplasms Mifepristone 17.2316525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 17.2317306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 17.2316936753
MESH:D010051 Ovarian Neoplasms U 0126 17.2316211241
MESH:D010146 Pain Tretinoin 2.6216870215
MESH:D010190 Pancreatic Neoplasms gemcitabine 14.8517440100 11504793 16929163 18992248 18383843
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 14.8516965848
MESH:D010190 Pancreatic Neoplasms Mitomycin 14.8515113037
MESH:D010190 Pancreatic Neoplasms Phenobarbital 14.8516965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 14.8515976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3511578682
MESH:D010300 Parkinson Disease Dieldrin 5.5811181820 17291500 11445065 16809432 16112328
MESH:D010300 Parkinson Disease Homocysteine 5.5816275827
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8712520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.7914722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.3116977796 15687265
MESH:D011041 Poisoning Diazinon 4.0217603234
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2118163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.9512371664
MESH:D011230 Precancerous Conditions Phenobarbital 7.952563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 14.1510548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 14.1517184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 14.1511399792 11896295 11222880 11118676
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.4115572423
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.4620887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.4620887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 4.0317292933
MESH:D011471 Prostatic Neoplasms bisphenol A 4.0316740699
MESH:D011471 Prostatic Neoplasms Calcitriol 4.0315754350 16644109 18247401 16289102 12479363
MESH:D011471 Prostatic Neoplasms Cholecalciferol 4.0317024972
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 4.0315846301 17136230 15046698
MESH:D011471 Prostatic Neoplasms Estradiol 4.0316740699
MESH:D011471 Prostatic Neoplasms Genistein 4.0315378649 15256057 16925846
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 4.0312376480 15682402
MESH:D011471 Prostatic Neoplasms Raloxifene 4.0316536755 16220300 15731164
MESH:D011471 Prostatic Neoplasms sodium arsenite 4.0316039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 4.0315067354
MESH:D011507 Proteinuria Tretinoin 3.2716636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.9515861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 4.1212752131
MESH:D011565 Psoriasis Cyclosporine 5.4516882103
MESH:D011565 Psoriasis Methotrexate 5.4517410198
MESH:D011625 Pterygium Tretinoin 4.4216723453
MESH:D011629 Puberty, Precocious bisphenol A 4.4210548101
MESH:D011693 Purpura Raloxifene 5.1815770314
MESH:D051437 Renal Insufficiency Folic Acid 9.5015728788
MESH:D051437 Renal Insufficiency Methotrexate 9.5017352296
MESH:D015427 Reperfusion Injury pirinixic acid 2.2019058328
MESH:D012135 Respiratory Sounds Chlorpyrifos 4.2816611668 11874814 17119214
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4918990726
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 4.5216611668 17119214
MESH:D012162 Retinal Degeneration Methylnitrosourea 4.1418155124 18172121
MESH:D012175 Retinoblastoma Methylnitrosourea 5.1211555667
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.7616116481 16283617
MESH:D012559 Schizophrenia Folic Acid 4.0616641680
MESH:D012559 Schizophrenia Homocysteine 4.0616641680
MESH:D012640 Seizures Phenobarbital 2.4516876388 3137016 4039156 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.456407741
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 5.716418539
MESH:D012871 Skin Diseases Folic Acid 7.6918709164
MESH:D012871 Skin Diseases halofuginone 7.6911874485
MESH:D012871 Skin Diseases monomethylarsonous acid 7.6917431481
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 12.0619755658 10029692
MESH:D012878 Skin Neoplasms sodium arsenite 12.0618572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.0616192470
MESH:D012878 Skin Neoplasms Tretinoin 12.0616467112
MESH:D013088 Spermatocele Diethylstilbestrol 17.9616709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 17.9616709447
MESH:D013088 Spermatocele Tamoxifen 17.9616709447
MESH:D013118 Spinal Cord Diseases Folic Acid 5.1216361298
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.6719457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5112854658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.4520155912 2093021
MESH:D013274 Stomach Neoplasms Folic Acid 4.4517171786
MESH:D013274 Stomach Neoplasms Methylnitrosourea 4.4515930296 16257854 18593901
MESH:D013274 Stomach Neoplasms Tretinoin 4.4517261132
MESH:D020521 Stroke Folic Acid 8.0516517955
MESH:D020521 Stroke Raloxifene 8.0516837676
MESH:D019966 Substance-Related Disorders bisphenol A 3.6216684133 16045194
MESH:D013576 Syndactyly Methotrexate 4.689562676
MESH:D013705 Temporomandibular Joint Disorders polyphenols 4.8817997062
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8515669648
MESH:D013953 Thymus Neoplasms Methylnitrosourea 4.8611418001
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5312697716
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 10.497505956 3078959
MESH:D013964 Thyroid Neoplasms Phenobarbital 10.491399818
MESH:D013964 Thyroid Neoplasms Tretinoin 10.4916026305 17045167
MESH:D013978 Tibial Fractures Estradiol 12.4619048282
MESH:D013978 Tibial Fractures Raloxifene 12.4619048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.4716051514
MESH:D014352 Trypanosomiasis Arsenicals 6.6515220340
MESH:D014376 Tuberculosis Tretinoin 3.0016040207
MESH:D001749 Urinary Bladder Neoplasms Arsenicals 21.8012846360
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 21.8017053015
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 21.8017306315 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 21.8020375083
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 21.8017572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 21.8016452187 16712894 17306315 11723127
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 21.8017572228 8653321 16712894
MESH:D014570 Urologic Diseases Diazinon 4.9016487989
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 14.0416175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 14.0411813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 14.0416129372
MESH:D014591 Uterine Diseases bisphenol A 12.5714652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 12.5714652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 8.3116690809 15809267
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.3114692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.2416752155
MESH:D014605 Uveitis Cyclosporine 3.611336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.0816513791 16002989
MESH:D014652 Vascular Diseases sodium arsenite 4.0617056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2212125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.8316837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2114671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.7116761959
MESH:D014846 Vulvar Neoplasms Raloxifene 5.1816343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8715886252
MESH:D009396 Wilms Tumor Tretinoin 3.6616287080
MESH:D014985 Xerophthalmia Cyclosporine 4.0717120751
Pathway ID Pathway Name
KEGG:05217 Basal cell carcinoma
KEGG:04340 Hedgehog signaling pathway
KEGG:04916 Melanogenesis
KEGG:05200 Pathways in cancer
REACT:14797 Signaling by GPCR
KEGG:04310 Wnt signaling pathway
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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