AutismKB 2.0

Annotation Detail for XRCC5


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:XRCC5 ( FLJ39089,KARP-1,KARP1,KU80,KUB2,Ku86,NFIV )
Gene Full Name: X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Band: 2q35
Quick LinksEntrez ID:7520; OMIM: 194364; Uniprot ID:XRCC5_HUMAN; ENSEMBL ID: ENSG00000079246; HGNC ID: 12833
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03450Non-homologous end-joining
Pathway IDPathway Name
DNA Repair
HIV Infection
Pathway IDPathway Name
200038Coregulation of Androgen receptor activity
200174BARD1 signaling events
200072Regulation of Telomerase
No data
Pathway IDPathway Name
500055Nonhomologous End-joining (NHEJ)
Related Diseases/Disorders Top
No data
No data
Desease Name
CANCER
cancer
esophageal cancer gastric cardiac adenocarcinoma
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of XRCC5 mRNAaffects expression 21346803
C054649 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of XRCC5 mRNAincreases expression 12734338
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of XRCC5 mRNAincreases expression 18648102
C086538 4-amino-1,8-naphthalimide XRCC5 protein affects the susceptibility to 4-amino-1,8-naphthalimideaffects response to substance 16556909
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of XRCC5 mRNAaffects expression 21346803
C013813 4-anisidine 4-anisidine results in decreased expression of XRCC5 mRNAdecreases expression 12929121
C016601 4-hydroxytamoxifen 4-hydroxytamoxifen results in decreased expression of XRCC5 mRNAdecreases expression 16514628
D000082 Acetaminophen Acetaminophen affects the expression of XRCC5 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of XRCC5 mRNAaffects expression 16483693
D001554 Benzene Benzene results in increased expression of XRCC5 mRNAincreases expression 15342939
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of XRCC5 mRNAincreases expression 20504355
D001761 Bleomycin XRCC5 protein affects the susceptibility to Bleomycinaffects response to substance 12384553
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of XRCC5 mRNAaffects cotreatment|decreases expression 20360939
D002259 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of XRCC5 mRNAdecreases expression 16039398
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of XRCC5 mRNAaffects cotreatment|affects expression 17602206
D003474 Curcumin Curcumin results in decreased expression of XRCC5 mRNAdecreases expression 17596214
D013759 Tetrahydrocannabinol Tetrahydrocannabinol results in decreased expression of XRCC5 mRNAdecreases expression 16039398
D002945 Cisplatin XRCC5 mRNA results in increased susceptibility to [Fluorouracil co-treated with Cisplatin]affects cotreatment|increases response to substance 18546291
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of XRCC5 mRNAaffects cotreatment|increases expression 19690152
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of XRCC5 mRNAaffects cotreatment|decreases expression 20360939
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of XRCC5 mRNAaffects cotreatment|affects expression 17602206
D004052 Diethylnitrosamine [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of XRCC5 mRNAaffects cotreatment|increases expression 18253720
18775883
D002117 Calcitriol Calcitriol results in decreased expression of XRCC5 mRNAdecreases expression 15951637
D004391 Dust Dust results in decreased expression of XRCC5 mRNAdecreases expression 17805423
D004958 Estradiol Estradiol results in increased expression of XRCC5 mRNAincreases expression 16514628
D000431 Ethanol [Fish Oils co-treated with Ethanol] results in increased expression of XRCC5 mRNAaffects cotreatment|increases expression 17347304
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of XRCC5 mRNAaffects expression 17555576
D005047 Etoposide XRCC5 protein affects the susceptibility to Etoposideaffects response to substance 12384553
D011345 Fenofibrate [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of XRCC5 mRNAaffects cotreatment|increases expression 18253720
18775883
D011345 Fenofibrate Fenofibrate results in increased expression of XRCC5 mRNAincreases expression 18775883
D005395 Fish Oils [Fish Oils co-treated with Ethanol] results in increased expression of XRCC5 mRNAaffects cotreatment|increases expression 17347304
D005472 Fluorouracil XRCC5 mRNA results in increased susceptibility to [Fluorouracil co-treated with Cisplatin]affects cotreatment|increases response to substance 18546291
C070081 fulvestrant fulvestrant results in decreased expression of XRCC5 mRNAdecreases expression 16514628
D006918 Hydroxyurea Hydroxyurea results in decreased expression of XRCC5 mRNAdecreases expression 12929121
D006918 Hydroxyurea Hydroxyurea results in increased mutagenesis of XRCC5 geneincreases mutagenesis 16868089
C051890 irinotecan irinotecan analog results in decreased expression of XRCC5 mRNAdecreases expression 18927307
C027869 lingzhi lingzhi results in decreased expression of XRCC5 proteindecreases expression 18422750
D008770 Methylnitrosourea Methylnitrosourea results in increased mutagenesis of XRCC5 geneincreases mutagenesis 16868089
D015741 Metribolone Metribolone results in decreased expression of XRCC5 proteindecreases expression 17152098
D009588 Nitrogen Mustard Compounds XRCC5 protein affects the susceptibility to Nitrogen Mustard Compoundsaffects response to substance 10717383
D017239 Paclitaxel Paclitaxel results in decreased expression of XRCC5 mRNAdecreases expression 12929121
D010882 Piperonyl Butoxide [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of XRCC5 mRNAaffects cotreatment|increases expression 19690152
D010882 Piperonyl Butoxide Piperonyl Butoxide affects the expression of XRCC5 mRNAaffects expression 17014948
C006253 pirinixic acid pirinixic acid results in increased expression of XRCC5 mRNAincreases expression 20127075
D020849 Raloxifene Raloxifene results in decreased expression of XRCC5 mRNAdecreases expression 16514628
D018038 Sodium Selenite Sodium Selenite results in increased expression of XRCC5 mRNAincreases expression 18175754
D014212 Tretinoin Tretinoin results in increased expression of XRCC5 proteinincreases expression 20888851
D014315 Triterpenes Triterpenes results in decreased expression of XRCC5 proteindecreases expression 18422750
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 7.417525203
MESH:D000014 Abnormalities, Drug-Induced Ethanol 7.4118926900 17676605
MESH:D000138 Acidosis Ammonium Chloride 9.0018287403
MESH:D000138 Acidosis Ethanol 9.0011192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.4917505938
MESH:D058186 Acute Kidney Injury Cisplatin 3.5715814532 12690470 17670903
MESH:D055371 Acute Lung Injury Bleomycin 8.0017118201
MESH:D055371 Acute Lung Injury pirinixic acid 8.0018653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 15.4120127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 15.4111798837 17638652
MESH:D000230 Adenocarcinoma Estradiol 15.4111473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 15.4114692618
MESH:D000230 Adenocarcinoma Fluorouracil 15.4117638652
MESH:D000230 Adenocarcinoma Methylnitrosourea 15.4115113128 15688392
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 9.583712494
MESH:D000236 Adenoma Benzo(a)pyrene 9.586695378
MESH:D000236 Adenoma Diethylnitrosamine 9.5810737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 8.6216434500 18056438 19052882 17620307 19061943 17162532
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.6216434500
MESH:D000419 Albuminuria Raloxifene 4.1717308373 17451421
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.8715451039 15451040
MESH:D019973 Alcohol-Related Disorders Curcumin 4.6317887948
MESH:D000505 Alopecia Tretinoin 3.2615955085
MESH:D000544 Alzheimer Disease Curcumin 4.0415590663
MESH:D000544 Alzheimer Disease Raloxifene 4.0415800139
MESH:D000690 Amyotrophic Lateral Sclerosis Tetrahydrocannabinol 4.5515204022
MESH:D000740 Anemia Fluorouracil 3.3315504547 17963324 16511603
MESH:D000741 Anemia, Aplastic Benzene 4.0314761424 11369114 17661222
MESH:D000799 Angioedema Acetaminophen 3.3910982225
MESH:D000853 Anophthalmos Ethanol 4.3915513904
MESH:D000860 Anoxia Bleomycin 4.9715782499
MESH:D001008 Anxiety Disorders Ethanol 3.6611141031
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.6419183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.0311256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.2715885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.2716412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 4.3216807698
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.3216292516
MESH:D001249 Asthma Tretinoin 2.2016456186
MESH:D050197 Atherosclerosis Curcumin 6.4518704882
MESH:D050197 Atherosclerosis Tetrahydrocannabinol 6.4515815632
MESH:D001284 Atrophy fulvestrant 4.4311514358
MESH:D001321 Autistic Disorder Acetaminophen 1.4718445737
MESH:D001327 Autoimmune Diseases Curcumin 4.0619761891
MESH:D001471 Barrett Esophagus Tretinoin 3.9816935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.571440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 7.6619483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 7.6616206674 16197459
MESH:D001855 Bone Marrow Diseases Benzene 4.7816183116
MESH:D019046 Bone Marrow Neoplasms Cisplatin 10.7214601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 10.7214601052
MESH:D001859 Bone Neoplasms Paclitaxel 4.1615867366
MESH:D001930 Brain Injuries Raloxifene 4.0416580743
MESH:D002545 Brain Ischemia Curcumin 3.8916770732
MESH:D001932 Brain Neoplasms Curcumin 3.5617596214
MESH:D001943 Breast Neoplasms Benzene 11.8217162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 11.8220146248 17474063
MESH:D001943 Breast Neoplasms Calcitriol 11.8211237771
MESH:D001943 Breast Neoplasms Cisplatin 11.8219526202 18382427
MESH:D001943 Breast Neoplasms Curcumin 11.8219250217 18462866 16243823 18593918
MESH:D001943 Breast Neoplasms Diethylnitrosamine 11.8217474063
MESH:D001943 Breast Neoplasms Estradiol 11.8217018787 17289903 18497071 12948864 17261762 16675129 19861407 14630087
MESH:D001943 Breast Neoplasms Etoposide 11.8216322251
MESH:D001943 Breast Neoplasms Fluorouracil 11.8216110121 16595493 18357371 19217205 15136595 18608205 16557594
MESH:D001943 Breast Neoplasms fulvestrant 11.8218984771
MESH:D001943 Breast Neoplasms Methylnitrosourea 11.8211306469 14633655 16253758
MESH:D001943 Breast Neoplasms Paclitaxel 11.8216115903 18234424 18323546 16273361 11325840 16244791 15136595 18223236
MESH:D001943 Breast Neoplasms Raloxifene 11.8215775269 17261762 17440819 16912660 17952589 15572757 17049068 17242785 17893378 16837676 17595753 15758505
MESH:D001943 Breast Neoplasms Tretinoin 11.8216873071 16166294 16443354
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.1516813970
MESH:D002056 Burns Ethanol 4.2216374292
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0216111702
MESH:D002252 Carbon Tetrachloride Poisoning lingzhi 5.3915673190
MESH:D002276 Carcinoid Tumor Fluorouracil 4.2216051944
MESH:D002277 Carcinoma Curcumin 7.4018593918
MESH:D002277 Carcinoma Fluorouracil 7.4017121937
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.7116168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 21.0516705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 21.053581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 21.053084413
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 21.0517982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 21.0511831363 20727157 20084675 16681979 20214788 20512989 17428255 16698587 18506893 16878318 16807293 19383236 18785209 19107877 17173139 20101231 19822196 10737359 19519916 18978308 18393292 16540662 19171122 18788625 16779866 18056438 17138121 19418558 19335982 16830150 20935162 18665156 19208518 18494052 17978847 20432363 16935385 18971187 16569478 20514400 19701751 18691550 17761372 17162532 20007298 16328049 16288022 20524982 19919837 3084413 17055752 19539802 19394651 19052882 21159647 18210153 16502159 3581430 10672840
MESH:D006528 Carcinoma, Hepatocellular Estradiol 21.0516924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 21.0515289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 21.0516332177 17971768 17045692 18930000 16799960 17088986
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 21.0516313753
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 21.051917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 5.2112023789 16685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 5.2118414057
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 5.767296757
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 5.7618695887
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 19.7320419170
MESH:D002294 Carcinoma, Squamous Cell Bleomycin 19.736189445
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 19.7311237771
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 19.736189445 18337622 17066447
MESH:D002294 Carcinoma, Squamous Cell Curcumin 19.7318462866
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 19.7318986760 17066447 16280240 16757204
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 19.7316051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.6917572228
MESH:D006332 Cardiomegaly Ethanol 3.1919332462
MESH:D002318 Cardiovascular Diseases Raloxifene 3.1415775269
MESH:D002375 Catalepsy Tetrahydrocannabinol 5.2810318961
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 15.5014694615
MESH:D002386 Cataract Acetaminophen 15.5010977129
MESH:D002386 Cataract Methylnitrosourea 15.5012484553
MESH:D002386 Cataract Tretinoin 15.5017460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 17.836135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 17.837505956
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 17.837505956 17174075 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 17.8318566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 17.837505956 2727394
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.1516129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.3119052882
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 11.4619486331 9022650
MESH:D002779 Cholestasis Ethinyl Estradiol 11.4616105132 17110522 16919318 11677210 17681005 15861022 17333356
MESH:D002779 Cholestasis pirinixic acid 11.4619176532
MESH:D002822 Choriocarcinoma Tretinoin 4.7116461808
MESH:D019457 Chromosome Breakage Sodium Selenite 4.3215894690
MESH:D002971 Cleft Lip Ethanol 3.3415513904
MESH:D002972 Cleft Palate Ethanol 5.4915513904
MESH:D002972 Cleft Palate Tretinoin 5.499407595
MESH:D003072 Cognition Disorders Raloxifene 4.1915800139
MESH:D003092 Colitis Curcumin 8.2118200517 16804969 16782535
MESH:D003092 Colitis Tretinoin 8.2117035595
MESH:D003103 Coloboma Curcumin 4.1518809619
MESH:D003110 Colonic Neoplasms Curcumin 5.3619359593 16340194
MESH:D003110 Colonic Neoplasms Fluorouracil 5.3616340194 17172411 15001691 17016597 17287894 18772588 17725105 16510598 17169374 17018589
MESH:D003110 Colonic Neoplasms irinotecan 5.3617287894 17725105
MESH:D015179 Colorectal Neoplasms Cisplatin 4.4415273666
MESH:D015179 Colorectal Neoplasms Fluorouracil 4.4416391804 16524972 18802399 17454858 18448328 17255274 18288408 16303861 18509181 17695437 15289873 16331619 14970324 18949393 15148649 17594712 16282729 17094418 20501625 17016601 18383874 17401013
MESH:D015179 Colorectal Neoplasms irinotecan 4.4416303861 17159606 16391804 15273666 18259882 18509181 17454858
MESH:D015179 Colorectal Neoplasms Paclitaxel 4.4418802399
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 3.7915095906
MESH:D016510 Corneal Neovascularization Curcumin 4.4618497527
MESH:D019465 Craniofacial Abnormalities Benzene 3.6515643154
MESH:D019465 Craniofacial Abnormalities Ethanol 3.6519302082 11873399 15513904 10194807 15451039 11198716 15451040
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.659125849 9211117 9664655 16925845 8800419 9224671 14991402 9142499 10589399 17551590
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.5918551238
MESH:D007644 Darier Disease Fluorouracil 4.3516733453
MESH:D003865 Depressive Disorder, Major Raloxifene 3.7917474826
MESH:D003872 Dermatitis Benzene 4.3315902427
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.4011298694 11906362 8970840 2524372 18759878 8156756 14531868 12868966
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2118249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.092952479 3621924
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.4116285004
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 4.1818403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.1820387270
MESH:D003928 Diabetic Nephropathies Curcumin 12.9418204486
MESH:D003928 Diabetic Nephropathies Estradiol 12.9419279558
MESH:D003928 Diabetic Nephropathies Raloxifene 12.9415920148 17451421 17308373
MESH:D003967 Diarrhea 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol 4.4810611417
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 16.3518551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 16.356679447 9653073 16192314 6482804 1440618 18692083 7440962 18289764 9328219 18648102 8291058 11289319 9022650
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 16.3521346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 16.3510774834 12540782 16081117 18071297 15968718 11287661 16227642 16781746 19923254 17906064 14986274 12705907 17562736 11461765 18713872 11743745 19085960 19739265 19370779 14725611 16485898 11739529 12153990 10915739 11529661 14550746 16177239 19416960 11834606 15619225 12958197 17522070 12392966 2444490 16109766 19164858 12594235 11421492 10663392 16393943 19420014
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 16.3519107877
MESH:D056486 Drug-Induced Liver Injury Ethanol 16.3511566570
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 16.3515131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6519426721
MESH:D004362 Drug Toxicity Cisplatin 3.5312231392 15033597 12649298 19839026
MESH:D004381 Duodenal Ulcer Curcumin 3.6317351913
MESH:D050171 Dyslipidemias Fenofibrate 4.1016707586
MESH:D004487 Edema Bleomycin 9.4217118201
MESH:D004487 Edema pirinixic acid 9.4212083418
MESH:D004487 Edema Raloxifene 9.4215860553
MESH:D004489 Edema, Cardiac Tretinoin 4.0218230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 12.9815138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 12.9812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 12.9815845917
MESH:D016889 Endometrial Neoplasms 4-hydroxytamoxifen 15.4419148513
MESH:D016889 Endometrial Neoplasms Estradiol 15.4418566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Fenofibrate 15.4416569247
MESH:D016889 Endometrial Neoplasms Tretinoin 15.4416569247
MESH:D004827 Epilepsy Tetrahydrocannabinol 4.25821787
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6616302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 15.733581430
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 15.7316530937
MESH:D004938 Esophageal Neoplasms Cisplatin 15.7316481741 15173087 16785472 17638652 15464296
MESH:D004938 Esophageal Neoplasms Ethanol 15.7316704527
MESH:D004938 Esophageal Neoplasms Fluorouracil 15.7315173087 17638652 16337965 16785472 16481741
MESH:D004938 Esophageal Neoplasms Paclitaxel 15.7316481741
MESH:D005124 Eye Abnormalities Tretinoin 3.259664655 16938888
MESH:D005234 Fatty Liver Curcumin 30.9119297423
MESH:D005234 Fatty Liver Diethylnitrosamine 30.9120387270 21071580
MESH:D005234 Fatty Liver Ethanol 30.9116409862 19236843 18620774
MESH:D005234 Fatty Liver Ethinyl Estradiol 30.9115345470
MESH:D005234 Fatty Liver Fish Oils 30.9118620774
MESH:D005234 Fatty Liver pirinixic acid 30.9120131406 19236843
MESH:D005234 Fatty Liver Raloxifene 30.9117473493
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.2117920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.8616946407 15513904 10194807 15451040
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.576705139
MESH:D005354 Fibrosarcoma Methylnitrosourea 4.7911555667
MESH:D005355 Fibrosis Curcumin 7.5718705752
MESH:D005355 Fibrosis Tretinoin 7.5717994277
MESH:D005756 Gastritis Acetaminophen 9.6316983495
MESH:D005756 Gastritis Ethanol 9.6315046732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.2618462866
MESH:D005909 Glioblastoma Curcumin 6.3117596214
MESH:D005909 Glioblastoma Tretinoin 6.3117312396
MESH:D005910 Glioma Fluorouracil 5.7416145905
MESH:D005910 Glioma Methylnitrosourea 5.749825942
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.637505956
MESH:D006258 Head and Neck Neoplasms Cisplatin 15.9815102660 15464296
MESH:D006258 Head and Neck Neoplasms Curcumin 15.9818462866 18829502
MESH:D006258 Head and Neck Neoplasms Fluorouracil 15.9818337622 15102660 15162350
MESH:D006258 Head and Neck Neoplasms Tretinoin 15.9816096774
MESH:D034381 Hearing Loss Cisplatin 3.9219898482
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.7116084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.0615464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 5.8420471113
MESH:D006330 Heart Defects, Congenital Tretinoin 5.8414991402 9664655
MESH:D006331 Heart Diseases Raloxifene 3.2311110106
MESH:D006333 Heart Failure pirinixic acid 2.2620558911
MESH:D006402 Hematologic Diseases Benzene 4.2516183116
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.106705139
MESH:D006529 Hepatomegaly pirinixic acid 2.5716221962 18467677 19176532 19772884
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.6117701891
MESH:D006558 Herpes Genitalis Estradiol 4.5815709030
MESH:D006561 Herpes Simplex Etoposide 4.1210809021
MESH:D006689 Hodgkin Disease Bleomycin 14.6415147373 17606976 18501091
MESH:D006689 Hodgkin Disease Cisplatin 14.6416200630 16170182
MESH:D006689 Hodgkin Disease Etoposide 14.6417606976 18180244 15147373 16200630 16135485
MESH:D006689 Hodgkin Disease Nitrogen Mustard Compounds 14.6416794504
MESH:D019584 Hot Flashes Estradiol 3.3017088409
MESH:D006930 Hyperalgesia Acetaminophen 11.0516870215
MESH:D006930 Hyperalgesia Ethanol 11.0518783367
MESH:D006930 Hyperalgesia Tretinoin 11.0516870215
MESH:D006937 Hypercholesterolemia Curcumin 3.6618704882
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.1416778211
MESH:D006943 Hyperglycemia pirinixic acid 2.8020558911
MESH:D006949 Hyperlipidemias Fish Oils 4.3515752949
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.5115034207
MESH:D006968 Hypersensitivity, Delayed Fish Oils 5.0511484837
MESH:D006973 Hypertension Benzene 5.0517940673
MESH:D006973 Hypertension Raloxifene 5.0517577099 15787275
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3816945680 16569931
MESH:D007035 Hypothermia Tetrahydrocannabinol 5.4910318961
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0512013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 9.6717937319
MESH:D007248 Infertility, Male fulvestrant 9.6711514358
MESH:D007248 Infertility, Male Methylnitrosourea 9.677193160
MESH:D007249 Inflammation Bleomycin 7.1917118201
MESH:D007249 Inflammation Curcumin 7.1918403477 16956363 17151092
MESH:D007249 Inflammation Diethylnitrosamine 7.1918785209
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.0218200517 18596194
MESH:D007333 Insulin Resistance Estradiol 10.6016627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 10.6016306350
MESH:D007333 Insulin Resistance Sodium Selenite 10.6014714311
MESH:D007410 Intestinal Diseases Tretinoin 3.3417994277
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 8.8310783313
MESH:D007414 Intestinal Neoplasms Curcumin 8.8310783313
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.578074119 9022650
MESH:D007569 Jaw Abnormalities Ethanol 9.0115513904
MESH:D007569 Jaw Abnormalities Tretinoin 9.0117551590 15992940
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.6915464296
MESH:D007674 Kidney Diseases Acetaminophen 12.3115629191 12587719
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 12.3115369732
MESH:D007674 Kidney Diseases Cisplatin 12.3112649298 18289764 19839026 15190930 12231392
MESH:D007674 Kidney Diseases Estradiol 12.3115618244
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 14.8216705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 14.826582329
MESH:D007680 Kidney Neoplasms Estradiol 14.8215610895
MESH:D007680 Kidney Neoplasms Fluorouracil 14.8216985049
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.3411231351
MESH:D007859 Learning Disorders Ethanol 3.7815451040
MESH:D007889 Leiomyoma Curcumin 9.8018555241
MESH:D007889 Leiomyoma Raloxifene 9.8016973256
MESH:D007938 Leukemia Benzene 9.2415935818 18335105 17119257 14694614
MESH:D007938 Leukemia Curcumin 9.2418462866
MESH:D007938 Leukemia Tretinoin 9.2417143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 3.8116106398
MESH:D007951 Leukemia, Myeloid Benzene 13.9217506065
MESH:D007951 Leukemia, Myeloid Hydroxyurea 13.9216532439
MESH:D007951 Leukemia, Myeloid Tretinoin 13.9219285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Benzene 3.7719478238
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.7717596541 19850784 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 6.9316766008
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 6.9319225113 17339181 19029980 16331271 17649720 17368321 16891316 16788101 17294898 19642359 17361223 16935935 16823087 19075265 17506722 17712046 12679006 19035177 16140955 9834237 16766008 15748426 17217047 17301526 17107899
MESH:D015458 Leukemia, T-Cell Curcumin 4.3416106398
MESH:D017880 Limb Deformities, Congenital Ethanol 11.9617676605
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 11.9615526292
MESH:D017880 Limb Deformities, Congenital Tretinoin 11.969224671
MESH:D008080 Liposarcoma Paclitaxel 4.4117353645
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 5.9720032147 18665156 19638242 18522880 18407596
MESH:D008103 Liver Cirrhosis Ethanol 5.9715289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.6518295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.9115034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 9.8718705752 17355460 18006644
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 9.8714716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 9.8718166357
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 9.8715474484
MESH:D008106 Liver Cirrhosis, Experimental lingzhi 9.8715673190
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 9.8715474484
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 9.8718397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 5.7619014921 16610002 19784758 11587558 19460945 12587719 16611625 12969438
MESH:D008107 Liver Diseases Curcumin 5.7616956363
MESH:D008107 Liver Diseases Diethylnitrosamine 5.7617034775
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.2217207112 17347304
MESH:D017114 Liver Failure, Acute Acetaminophen 2.8517185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 22.687678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 22.6820195826 21137059
MESH:D008113 Liver Neoplasms Clofibric Acid 22.6817602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 22.6819996281 19427195 18978307 19426721 19294768 19638242 19255062 21167192 19850985 12771043 15885732 9163691 2862719 20452335 2422723 18648771 20583210 20137499 19551842 19499222 20501860 19254457 20118626 16942905 19090486 10737359 20434301 12112319 20405173 21071580 19642983 18644402 21278145 18977376 19812893 19073162 19833225 21047994 20101389 15175105 18754104 19256749 19690152 20492335
MESH:D008113 Liver Neoplasms Fenofibrate 22.6818978307
MESH:D008113 Liver Neoplasms Fluorouracil 22.6816603448 17045692 18383874 15113037
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 22.6819690152 20101389 15890375 18648771
MESH:D008113 Liver Neoplasms pirinixic acid 22.6820007298 15890375 16377806
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 15.662876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 15.66598648 1399818 3712494 6587162
MESH:D008114 Liver Neoplasms, Experimental Benzene 15.6612562636
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 15.6618282651 19126423 19519916 18093689 16267830 18079962 2563599 3124819 19539802 9362446 17854601 18253720 19004024 18775883 17174075 18544905 16842330 18308698 21159647 17942915 19009564 18164116
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 15.6618253720 18775883
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 5.0316080182
MESH:D017563 Lung Diseases, Interstitial Benzene 4.3614698565
MESH:D008175 Lung Neoplasms Benzene 11.7912562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 11.7918816296 18520028 18569708 17053015 20464547 20869020 20135361 20064080 6695378
MESH:D008175 Lung Neoplasms Bleomycin 11.796189445
MESH:D008175 Lung Neoplasms Cisplatin 11.7911798837 17225452 6189445
MESH:D008175 Lung Neoplasms Curcumin 11.7918462866 16243823 19359593
MESH:D008175 Lung Neoplasms Diethylnitrosamine 11.796695378 20970405 21163286 20512841
MESH:D008175 Lung Neoplasms Fluorouracil 11.7915246190
MESH:D008175 Lung Neoplasms Methylnitrosourea 11.7918062963
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.3515086387
MESH:D008223 Lymphoma Benzene 15.3617584886 17119257
MESH:D008223 Lymphoma Curcumin 15.3618462866
MESH:D008223 Lymphoma Etoposide 15.3612556972 12854902
MESH:D008223 Lymphoma Methylnitrosourea 15.3611418001 16257854
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 9.0914633661
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 9.0914737004
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.7314749477
MESH:D016399 Lymphoma, T-Cell Curcumin 4.2616173963
MESH:D015674 Mammary Neoplasms, Animal Benzene 4.0012562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 8.4811921183
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 8.4817203775 16891317 11807958 11408345
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 8.4816944150 15113128 14999141 12931682 15688392 16619500 15313902 16827153 17020996 16051031 10767621 10838139 17131329 11751437 19196723 11807958 14633655
MESH:D020149 Manganese Poisoning Estradiol 4.0319453300
MESH:D008527 Medulloblastoma Tretinoin 2.6017453147
MESH:D008545 Melanoma Bleomycin 8.8115577320
MESH:D008545 Melanoma Cisplatin 8.8116809738 12374674 15577323 16248763 16432458 18176117 18505091 17023156 12393984 18332650 12883367 11135225 17761969
MESH:D008545 Melanoma Curcumin 8.8117885582 18462866
MESH:D008545 Melanoma Paclitaxel 8.8112025231 12040289 16342250
MESH:D008545 Melanoma Tretinoin 8.8116752155
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.3315990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1419513568
MESH:D008569 Memory Disorders Curcumin 8.3617263510
MESH:D008569 Memory Disorders Ethanol 8.3618411066 15451040
MESH:D008591 Meningomyelocele Tretinoin 3.9916940565
MESH:D008654 Mesothelioma Cisplatin 3.0617638057
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.1015863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.4016381670
MESH:D009062 Mouth Neoplasms Fluorouracil 7.4016757204 18986760
MESH:D052016 Mucositis irinotecan 4.5717159606
MESH:D009101 Multiple Myeloma Benzene 14.7217119195
MESH:D009101 Multiple Myeloma Curcumin 14.7219372569
MESH:D009101 Multiple Myeloma Paclitaxel 14.7214749477
MESH:D009101 Multiple Myeloma Raloxifene 14.7216497877
MESH:D009128 Muscle Spasticity 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol 5.6617220914
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.4717962980
MESH:D009135 Muscular Diseases pirinixic acid 3.0816239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.8217596541
MESH:D009203 Myocardial Infarction pirinixic acid 1.9519151258
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.1216810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.1216411023
MESH:D009232 Myxoma Raloxifene 5.1016343187
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.4218551238 7678174
MESH:D009361 Neoplasm Invasiveness Curcumin 3.9518495463
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 12.033581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 12.033581430 9029167
MESH:D009362 Neoplasm Metastasis irinotecan 12.0318259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 12.0315867366
MESH:D009369 Neoplasms Benzo(a)pyrene 16.7711141357
MESH:D009369 Neoplasms Cisplatin 16.7716773208
MESH:D009369 Neoplasms Fluorouracil 16.7716928823 18600527 18239605
MESH:D009369 Neoplasms Methylnitrosourea 16.7715533788
MESH:D009369 Neoplasms pirinixic acid 16.7717405874
MESH:D009369 Neoplasms Tretinoin 16.7716594593 16946489
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 4.0512696579
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 4.0812497104
MESH:D009389 Neovascularization, Pathologic Estradiol 3.2917289903
MESH:D009395 Nephritis, Interstitial Cisplatin 4.0415464296
MESH:D009421 Nervous System Malformations Estradiol 8.2816427766 11399458
MESH:D009421 Nervous System Malformations Tretinoin 8.289125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.1818462866
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 15.006679447
MESH:D009436 Neural Tube Defects Benzene 15.0015643154
MESH:D009436 Neural Tube Defects Tetrahydrocannabinol 15.0019040278
MESH:D009436 Neural Tube Defects Tretinoin 15.009142499
MESH:D009442 Neurilemmoma Methylnitrosourea 5.0411555667
MESH:D009447 Neuroblastoma Cisplatin 6.428761367
MESH:D009447 Neuroblastoma irinotecan 6.428761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.9918514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 6.9920387270
MESH:D017599 Neuroectodermal Tumors Cisplatin 9.998761367
MESH:D017599 Neuroectodermal Tumors irinotecan 9.998761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6620387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.1316436463
MESH:D009765 Obesity Curcumin 4.1819297423
MESH:D009765 Obesity pirinixic acid 4.1820558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 18.4816049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 18.486482804 4026338
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 18.4814694615
MESH:D009784 Occupational Diseases Benzene 18.4815612468 15576619 17119257 15727169 17178637 15935809 16737584 17479406 15913788
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.573988306
MESH:D010014 Osteolysis Paclitaxel 4.5415867366
MESH:D010024 Osteoporosis Curcumin 6.4818719352
MESH:D010024 Osteoporosis Raloxifene 6.4817882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 3.8217893378 17823083 15758505 15579764
MESH:D010051 Ovarian Neoplasms Benzene 16.8212562636
MESH:D010051 Ovarian Neoplasms Cisplatin 16.8219769630 15464296 6897625 17225452
MESH:D010051 Ovarian Neoplasms Curcumin 16.8218462866 19020741
MESH:D010051 Ovarian Neoplasms Estradiol 16.8219401270
MESH:D010051 Ovarian Neoplasms Paclitaxel 16.8211161223
MESH:D010051 Ovarian Neoplasms Tretinoin 16.8216936753
MESH:D010146 Pain Acetaminophen 5.4116870215
MESH:D010146 Pain Tretinoin 5.4116870215
MESH:D010190 Pancreatic Neoplasms Cisplatin 26.2719003803
MESH:D010190 Pancreatic Neoplasms Curcumin 26.2717440100 19401701 19196508
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 26.2716540662
MESH:D010190 Pancreatic Neoplasms Ethanol 26.2712384795
MESH:D010190 Pancreatic Neoplasms Etoposide 26.2719003803
MESH:D010190 Pancreatic Neoplasms Fluorouracil 26.2715113037 16929163 16500647 19003803
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 26.2716965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 26.2715976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2811578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.067296757
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.8915464296
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.026228378
MESH:D010997 Pleural Neoplasms Cisplatin 4.8917638057
MESH:D011014 Pneumonia Bleomycin 4.9716317386 17071938 18024389
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.182563599
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.3415572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.4920887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.3117292933
MESH:D011471 Prostatic Neoplasms Calcitriol 3.3116289102 15754350 16644109 12479363 18247401
MESH:D011471 Prostatic Neoplasms Curcumin 3.3118226269 12497104 15129424 18156803 11398177 18769126 10851300
MESH:D011471 Prostatic Neoplasms Estradiol 3.3116740699
MESH:D011471 Prostatic Neoplasms Etoposide 3.3117172428
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.3119082440 18626508
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 3.3115682402 12376480
MESH:D011471 Prostatic Neoplasms Paclitaxel 3.3116729912 17136230 17172428 16356831
MESH:D011471 Prostatic Neoplasms Raloxifene 3.3115731164 16220300 16536755
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3118760546
MESH:D011507 Proteinuria Tretinoin 3.2016636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.8715861022 16919318
MESH:D011625 Pterygium Tretinoin 4.3516723453
MESH:D011654 Pulmonary Edema Bleomycin 4.8715808516
MESH:D011656 Pulmonary Emphysema Curcumin 4.1419168576
MESH:D011658 Pulmonary Fibrosis Bleomycin 3.6915322207 15541506 17177178 21435439 14609568 18162602 18008008 11554783 17434272 16314464 12574379 16115399 17241526 12624602
MESH:D011693 Purpura Raloxifene 5.1015770314
MESH:D012004 Rectal Neoplasms Fluorouracil 3.6416160472 15538739 18722050 18286688
MESH:D051437 Renal Insufficiency Cisplatin 3.9815464296
MESH:D015427 Reperfusion Injury pirinixic acid 2.1619058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.6218379247 10666014
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 8.013692021
MESH:D012162 Retinal Degeneration Methylnitrosourea 8.0118172121 18155124
MESH:D012175 Retinoblastoma Methylnitrosourea 5.0411555667
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.6916116481 16283617
MESH:D012509 Sarcoma Curcumin 3.7318462866
MESH:D012512 Sarcoma, Ewing's Cisplatin 9.2214601052
MESH:D012512 Sarcoma, Ewing's Etoposide 9.2214601052
MESH:D012640 Seizures 2,6-dinitrotoluene 5.1018551238
MESH:D012640 Seizures Ethanol 5.109754883
MESH:D018805 Sepsis Curcumin 3.7118389075
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 4.9419755658 10029692
MESH:D012878 Skin Neoplasms Tretinoin 4.9416467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.8915464296
MESH:D013088 Spermatocele Ethinyl Estradiol 3.4916709447
MESH:D013274 Stomach Neoplasms Benzene 16.2112562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 16.212093021 20155912
MESH:D013274 Stomach Neoplasms Cisplatin 16.2117522103 18396642 15958060
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 16.2118456281
MESH:D013274 Stomach Neoplasms Ethanol 16.2118456281
MESH:D013274 Stomach Neoplasms Fluorouracil 16.2115786421 16951190 17498489 19015929 16424979 18567086 17522103 17172411 19084572 18396642
MESH:D013274 Stomach Neoplasms irinotecan 16.2115723263
MESH:D013274 Stomach Neoplasms Methylnitrosourea 16.2116257854 18593901 15930296
MESH:D013274 Stomach Neoplasms Paclitaxel 16.2118396642 18506536
MESH:D013274 Stomach Neoplasms Tretinoin 16.2117261132
MESH:D013276 Stomach Ulcer Curcumin 10.1319188055 16631530
MESH:D013276 Stomach Ulcer Ethanol 10.1311906479 9211565 16755016 17189318 17918041 9562338
MESH:D013276 Stomach Ulcer lingzhi 10.1312467913
MESH:D020521 Stroke Raloxifene 3.4716837676
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.879754883
MESH:D024801 Tauopathies Paclitaxel 4.3716930453
MESH:D013736 Testicular Neoplasms Cisplatin 4.2215464296 17225452
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7815669648
MESH:D013953 Thymus Neoplasms Benzene 10.7510850423
MESH:D013953 Thymus Neoplasms Methylnitrosourea 10.7511418001
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 14.371399818 6582329 6587162 3712494 7505956
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 14.377505956
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 14.377505956 3078959
MESH:D013964 Thyroid Neoplasms Tretinoin 14.3717045167 16026305
MESH:D013978 Tibial Fractures Estradiol 12.2119048282
MESH:D013978 Tibial Fractures Raloxifene 12.2119048282
MESH:D014062 Tongue Neoplasms Fluorouracil 8.5516280240
MESH:D014062 Tongue Neoplasms Tretinoin 8.5516051514
MESH:D014376 Tuberculosis Tretinoin 2.9516040207
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 17.4116049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 17.418074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 17.4117053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 17.4112973940 17225452 15464296
MESH:D001749 Urinary Bladder Neoplasms Curcumin 17.4118593936
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 17.4117572228
MESH:D014565 Urogenital Neoplasms Curcumin 4.8218462866
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.8810091137
MESH:D014581 Urticaria Acetaminophen 2.5710982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 13.7016803524
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 13.7016803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 13.7016129372
MESH:D014594 Uterine Neoplasms Benzene 8.1812562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.1814692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.1616752155
MESH:D014625 Vaginal Neoplasms Cisplatin 4.1815577323
MESH:D054556 Venous Thromboembolism Raloxifene 4.7616837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1414671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.6416761959
MESH:D014839 Vomiting Cisplatin 4.2711897121
MESH:D014846 Vulvar Neoplasms Raloxifene 5.1016343187
MESH:D015431 Weight Loss Bleomycin 5.2012624602
MESH:D009396 Wilms Tumor Tretinoin 3.5916287080
Pathway ID Pathway Name
REACT:216 DNA Repair
REACT:6185 HIV Infection
KEGG:03450 Non-homologous end-joining
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA37425
    • No data
    Releated disease ID Related disease Name
    PA446969Venous Thrombosis
    PA443622Carcinoma, Non-Small-Cell Lung
    Releated drug ID Related drug Name
    PA451581tamoxifen
    PA451644thalidomide
    PA449014cisplatin
    PA449748gemcitabine
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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