AutismKB 2.0

Annotation Detail for YWHAB


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Basic Information Top
Gene Symbol:YWHAB ( GW128,HS1,KCIP-1,YWHAA )
Gene Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
Band: 20q13.12
Quick LinksEntrez ID:7529; OMIM: 601289; Uniprot ID:1433B_HUMAN; ENSEMBL ID: ENSG00000166913; HGNC ID: 12849
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY66-14MAP kinase cascade
Pathway IDPathway Name
hsa04722Neurotrophin signaling pathway
hsa04110Cell cycle
hsa04114Oocyte meiosis
Pathway IDPathway Name
Signalling by NGF
Axon guidance
Apoptosis
Signaling by EGFR
Signaling by Insulin receptor
Signaling by PDGF
Signaling in Immune system
Pathway IDPathway Name
200019Signaling events mediated by HDAC Class II
Pathway IDPathway Name
P00018EGF receptor signaling pathway
P00049Parkinson disease
P00021FGF signaling pathway
Pathway IDPathway Name
500261Activation of BAD and translocation to mitochondria
500080RAF activation
500630Frs2-mediated activation
500631ARMS-mediated activation
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of YWHAB mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of YWHAB mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of YWHAB mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of YWHAB proteindecreases expression 19364129
D001194 Asbestos Asbestos affects the expression of YWHAB mRNAaffects expression 17297452
D002994 Clofibrate PPARA protein affects the reaction [Clofibrate results in increased expression of YWHAB mRNA]affects reaction|increases expression 17585979
D003024 Clozapine Clozapine results in decreased expression of YWHAB mRNAdecreases expression 17266109
D004041 Dietary Fats Dietary Fats results in decreased expression of YWHAB mRNAdecreases expression 18042831
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of YWHAB mRNAincreases expression 15766595
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of YWHAB mRNAincreases expression 17942748
17555576
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of YWHAB mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of YWHAB mRNAaffects expression 16079270
C027869 lingzhi lingzhi results in decreased expression of YWHAB proteindecreases expression 18422750
D009532 Nickel MT1 affects the reaction [Nickel affects the expression of YWHAB mRNA]affects expression|affects reaction 16166738
D009532 Nickel MT2 affects the reaction [Nickel affects the expression of YWHAB mRNA]affects expression|affects reaction 16166738
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of YWHAB mRNAincreases expression 17616710
C041786 palm oil palm oil results in decreased expression of YWHAB mRNAdecreases expression 18042831
D010622 Phencyclidine Phencyclidine results in decreased expression of YWHAB mRNAdecreases expression 17266109
D018038 Sodium Selenite Sodium Selenite results in increased expression of YWHAB mRNAincreases expression 18175754
D013629 Tamoxifen Tamoxifen affects the expression of YWHAB mRNAaffects expression 17555576
C004648 testosterone enanthate testosterone enanthate affects the expression of YWHAB mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of YWHAB mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of YWHAB mRNAincreases expression 17942748
D014315 Triterpenes Triterpenes results in decreased expression of YWHAB proteindecreases expression 18422750
D014501 Uranium Uranium affects the expression of YWHAB proteinaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of YWHAB proteinaffects expression 15672453
C025643 vinclozolin vinclozolin affects the expression of YWHAB mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.4014745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7011752688 14514962 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.4118287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7917505938
MESH:D055371 Acute Lung Injury Nickel 4.4416166738
MESH:D000230 Adenocarcinoma arsenic trioxide 4.1619825857 11798837
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1614692618
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.2316835633
MESH:D000380 Agranulocytosis Clozapine 4.9016160616 14617031 12649775
MESH:D000686 Amyloidosis Diethylstilbestrol 4.3315469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8111748828
MESH:D001008 Anxiety Disorders vinclozolin 3.5219015723
MESH:D001161 Arteriosclerosis Dietary Fats 9.4115238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.4111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5715885639
MESH:D050197 Atherosclerosis Asbestos 4.1318795166
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 14.6216206674
MESH:D001778 Blood Coagulation Disorders Clofibrate 14.6219483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.6212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6715746008
MESH:D001943 Breast Neoplasms Dietary Fats 2.3020435547
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.3015324884 17129689
MESH:D001943 Breast Neoplasms Nickel 2.3015986119
MESH:D001943 Breast Neoplasms Tamoxifen 2.3019084267 18984771 19011961 17049068 15565566 19289846 20859285 18855134 16873071 21138602 17440819 16202921 19221464 18351453 15668708 20135344 18815881 20065188 17893378 11161223 19115204 19189212 20544844 19103187 21152245 18997820 19487384 19410462 19066611 20005174 16818667 18821012 19244106 20390343 18425577 17242785 19288272 17261762 16273361 19155303 19142967 19059307 19189210 18629630 19200415
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3020435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1911589617
MESH:D002252 Carbon Tetrachloride Poisoning lingzhi 5.6715673190
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6816835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3519066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 8.6116705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 8.6116705839
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 8.6115553829 11135700 16217749 15073043 14691202
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 8.6115948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.6116924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7219014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9812490120
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.4817572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2818850075 18670907 16120746
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 6.606135515
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 6.601399818
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0316835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.7616105132 11677210 16919318 17333356 17681005 15861022 17110522
MESH:D019457 Chromosome Breakage Sodium Selenite 4.6015894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0416354765 15668235 8697196 15340226 12621046
MESH:D003072 Cognition Disorders Clozapine 4.8117123785
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9314669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0412609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.4210525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4210048152 20055451 15322242
MESH:D003456 Cryptorchidism Diethylstilbestrol 10.8816002989 12952375
MESH:D003456 Cryptorchidism vinclozolin 10.8814966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.3918551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.3918551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9515213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.2119031437
MESH:D017449 Dermatitis, Allergic Contact Nickel 3.8017244072 19470301 17100760
MESH:D003877 Dermatitis, Contact Nickel 4.492952479
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.6516285004
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 4.3816402076
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.3817107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.3519279558
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.4015331141
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 8.6018551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 8.6021346803 18551238
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 8.6015131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.6020420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6511462148
MESH:D050171 Dyslipidemias Clofibrate 13.9916707586
MESH:D050171 Dyslipidemias Clozapine 13.9916402076
MESH:D050171 Dyslipidemias Dietary Fats 13.9918367378
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.2412711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7516714409 18230668 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.4612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.4619031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.5416402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 7.2415700306 16804899
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.2420544844 16202921 17893378 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8910568697 9294722
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.5912903497
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 4.5916704527 15264214 15547721 15878914 15623463 15150132 16805852 16510608 15547733
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9011564622
MESH:D005234 Fatty Liver arsenic trioxide 23.1915073043
MESH:D005234 Fatty Liver Clofibrate 23.1919224547
MESH:D005234 Fatty Liver Dietary Fats 23.1918296743 17967931 19551842 19004024
MESH:D005234 Fatty Liver Ethinyl Estradiol 23.1915345470
MESH:D005234 Fatty Liver Tamoxifen 23.1919224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.9116534752 16513791 16611131 16002989 15751030
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.9116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3111858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.3814745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.0319069698
MESH:D005355 Fibrosis Dietary Fats 8.1218296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.1220067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1116904648
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.7816973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.1516417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.7916452187
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4410696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2511294989 10048152
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2011000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.7415340226 16120746 12621046
MESH:D015658 HIV Infections Nickel 3.7417263646
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.6017440010
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8915340226 16959395 16354765 18606429 8697196
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4521332399
MESH:D006948 Hyperkinesis Clozapine 4.7616046005
MESH:D006949 Hyperlipidemias Dietary Fats 3.4721332399
MESH:D006965 Hyperplasia Diethylstilbestrol 4.2914722030 12960047
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8518850075 18670907
MESH:D007021 Hypospadias Diethylstilbestrol 10.7416002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.7416945680 16569931
MESH:D007246 Infertility Diethylstilbestrol 4.2115036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.3317937319
MESH:D007248 Infertility, Male vinclozolin 6.3316467254
MESH:D007249 Inflammation Dietary Fats 11.3520412841
MESH:D007249 Inflammation Nickel 11.3516166738
MESH:D007249 Inflammation Tamoxifen 11.3519457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.3512200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 7.1618457598 11836018
MESH:D007333 Insulin Resistance Sodium Selenite 7.1614714311
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2016580747
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 16.7616705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 16.7616705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 16.7614681315 16762066 15003126
MESH:D007680 Kidney Neoplasms Tamoxifen 16.7618625569
MESH:D007859 Learning Disorders Diethylstilbestrol 3.9117184923
MESH:D007938 Leukemia arsenic trioxide 2.7615070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6612560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.6219077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1117050201 19850784 20471514 16968895 16467208
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.1215213294 16112521 19075265 12679006 15622746 19035177 16823087 19225113 16891316 15336539 19642359 12018890 17217047 17869043 16330433 17107899 12712474 16966277 11468182 9834237 17649720 15748426 17712046 16331271 11161223
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2016882451
MESH:D007984 Leydig Cell Tumor vinclozolin 4.5816417039
MESH:D008064 Lipidoses Clozapine 7.7217567588
MESH:D008064 Lipidoses Tamoxifen 7.7217567588 15342952
MESH:D008103 Liver Cirrhosis Dietary Fats 2.8018296743
MESH:D008106 Liver Cirrhosis, Experimental lingzhi 3.6215673190
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.6218564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.6212878042
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 13.637678174
MESH:D008113 Liver Neoplasms arsenic trioxide 13.6314682389
MESH:D008113 Liver Neoplasms Diethylstilbestrol 13.6316712894 15890375
MESH:D008113 Liver Neoplasms Tamoxifen 13.6316684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 13.6316984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 9.252876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 9.2520377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.2512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2315213294
MESH:D008175 Lung Neoplasms arsenic trioxide 4.7519825857 11798837
MESH:D008175 Lung Neoplasms Asbestos 4.7512111688
MESH:D008175 Lung Neoplasms Tamoxifen 4.7518625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.7511884234 19555203
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.0015166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.3715700306
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 3.9214737004
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.3616002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.6119428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.5314580682 19196722 11731420 19196723 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.4019453300
MESH:D008545 Melanoma Tamoxifen 1.8612393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.0315990972
MESH:D001523 Mental Disorders Clozapine 3.8016856516
MESH:D008654 Mesothelioma Asbestos 4.0318709470 16919927 18310086 16319530 16564556
MESH:D024821 Metabolic Syndrome X Clozapine 4.2919142101
MESH:D009101 Multiple Myeloma arsenic trioxide 3.0015949261 19549372 11468182 14977855 19417148
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0616882451 16105982
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9012213967
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.8418551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.8418551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8116624393
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.4919393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4719410462
MESH:D009369 Neoplasms Diethylstilbestrol 2.7015313581
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.8519189210 19200415 19196722
MESH:D009421 Nervous System Malformations Diethylstilbestrol 9.1511399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.1514600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.0210525206
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.799802331
MESH:D009765 Obesity Clozapine 4.7519142110 18515891
MESH:D009765 Obesity Dietary Fats 4.7519632207 18457598 20518802 16723640 21332399 20132043 18674790 17217161 11836018
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.4416049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.4416049721
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.3619769630 12452020 16624393
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.4715580305
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5411578682
MESH:D010235 Paraganglioma arsenic trioxide 4.0219927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1012520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.0214722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.5215687265 16977796
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4118163543
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 15.3917184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.3911222880 11896295 11399792 11118676
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 15.3918220299 19015723 18042343
MESH:D011469 Prostatic Diseases vinclozolin 4.7818220299
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.1219131511
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.1215046698 15846301 17136230
MESH:D011471 Prostatic Neoplasms Sodium Selenite 2.1218760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1215067354
MESH:D011472 Prostatitis vinclozolin 4.7818629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.1616919318 15861022
MESH:D011618 Psychotic Disorders Clozapine 4.0815331141
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6918990726
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.8116646077
MESH:D012559 Schizophrenia Clozapine 2.7217667964 20452607 18855531 20521320 20580759 20521326 17726453 11763009 20107430 16141801 20168265 19369910 11151749 17123785 18806925
MESH:D012640 Seizures 2,4-dinitrotoluene 5.5318551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.5318551238
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 1.9716192470
MESH:D013088 Spermatocele Diethylstilbestrol 19.2616002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 19.2616709447
MESH:D013088 Spermatocele Tamoxifen 19.2616709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.8919457130
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.6117007042
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 2.6112958204 17575124
MESH:D013276 Stomach Ulcer lingzhi 4.8712467913
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7512697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 2.9719014326
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8115213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 15.1816049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 15.1816049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 15.1820435036 12973940 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 15.1816452187 16712894 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 15.1816712894 8653321 17572228
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.4810091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.4810091137
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 3.9016175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.0214652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 8.9815809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.9814692618
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.2916002989 16513791
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4412125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4015869587 14671159
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1015886252
MESH:D015430 Weight Gain Clozapine 9.3916141801 20107430 20564506 20521320 17502770 16402076
MESH:D015430 Weight Gain Dietary Fats 9.3916723640
MESH:D015431 Weight Loss Clozapine 4.9217933447
Pathway ID Pathway Name
REACT:578 Apoptosis
REACT:18266 Axon guidance
KEGG:04110 Cell cycle
REACT:21257 Metabolism of RNA
KEGG:04722 Neurotrophin signaling pathway
KEGG:04114 Oocyte meiosis
REACT:9417 Signaling by EGFR
REACT:498 Signaling by Insulin receptor
REACT:16888 Signaling by PDGF
REACT:6900 Signaling in Immune system
REACT:11061 Signalling by NGF
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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