AutismKB 2.0

Annotation Detail for YWHAG


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Basic Information Top
Gene Symbol:YWHAG ( 14-3-3GAMMA )
Gene Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Band: 7q11.23
Quick LinksEntrez ID:7532; OMIM: 605356; Uniprot ID:1433G_HUMAN; ENSEMBL ID: ENSG00000170027; HGNC ID: 12852
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04722Neurotrophin signaling pathway
hsa04110Cell cycle
hsa04114Oocyte meiosis
Pathway IDPathway Name
Cell Cycle, Mitotic
No data
Pathway IDPathway Name
P00018EGF receptor signaling pathway
P00049Parkinson disease
P00021FGF signaling pathway
Pathway IDPathway Name
500383Loss of proteins required for interphase microtubule organization from the centrosome
500384Loss of Nlp from mitotic centrosomes
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of YWHAG mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of YWHAG mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane affects the expression of YWHAG mRNAaffects expression 18648102
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of YWHAG mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of YWHAG mRNAaffects expression 17562736
D000638 Amiodarone Amiodarone affects the expression of YWHAG mRNAaffects expression 19483382
D000643 Ammonium Chloride Ammonium Chloride affects the expression of YWHAG mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of YWHAG proteindecreases expression 19364129
D001553 Benzbromarone Benzbromarone affects the expression of YWHAG mRNAaffects expression 19483382
D002713 Chlorine Chlorine results in increased expression of YWHAG mRNAincreases expression 18636392
D002713 Chlorine [Ozone co-treated with Chlorine] affects the expression of YWHAG mRNAaffects cotreatment|affects expression 18636392
D002994 Clofibrate Clofibrate affects the expression of YWHAG mRNAaffects expression 19483382
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of YWHAG mRNAaffects cotreatment|affects expression 17602206
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of YWHAG mRNAincreases expression 17654400
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of YWHAG mRNAaffects cotreatment|affects expression 17602206
D000431 Ethanol Ethanol results in increased expression of YWHAG mRNAincreases expression 15353170
D005001 Ethionine Ethionine affects the expression of YWHAG mRNAaffects expression 19483382
C056933 fumonisin B1 fumonisin B1 results in increased expression of YWHAG mRNAincreases expression 16221962
D005978 Glutathione Glutathione deficiency results in increased expression of YWHAG mRNAincreases expression 15345336
D007657 Ketone Bodies Ketone Bodies results in decreased expression of YWHAG mRNAdecreases expression 15469884
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of YWHAG mRNAincreases expression 17616710
D009853 Omeprazole Omeprazole affects the expression of YWHAG mRNAaffects expression 19483382
D010126 Ozone [Ozone co-treated with Chlorine] affects the expression of YWHAG mRNAaffects cotreatment|affects expression 18636392
C006253 pirinixic acid pirinixic acid results in increased expression of YWHAG mRNAincreases expression 18301758
16221962
C006253 pirinixic acid pirinixic acid affects the expression of YWHAG mRNAaffects expression 19483382
D011441 Propylthiouracil Propylthiouracil affects the expression of YWHAG mRNAaffects expression 19483382
D013853 Thioacetamide Thioacetamide affects the expression of YWHAG mRNAaffects expression 19483382
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 8.247525203
MESH:D000014 Abnormalities, Drug-Induced Ethanol 8.2418926900 17676605
MESH:D000138 Acidosis Ammonium Chloride 9.8318287403
MESH:D000138 Acidosis Ethanol 9.8311192467
MESH:D055371 Acute Lung Injury Chlorine 8.5520601635
MESH:D055371 Acute Lung Injury pirinixic acid 8.5518653653
MESH:D000230 Adenocarcinoma arsenic trioxide 2.2411798837 19825857
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.303712494
MESH:D000236 Adenoma Diethylnitrosamine 6.3010737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.4517620307 19052882 17162532 16434500 19061943 18056438
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.4516434500
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.1315451040 15451039
MESH:D000544 Alzheimer Disease Ozone 2.4015513908
MESH:D000799 Angioedema Acetaminophen 3.6510982225
MESH:D000853 Anophthalmos Ethanol 4.6315513904
MESH:D001008 Anxiety Disorders Ethanol 3.8511141031
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.6418057881 18218290 20041841
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5115570426
MESH:D001249 Asthma Ozone 2.5816373670 17854713
MESH:D001281 Atrial Fibrillation Amiodarone 3.7619698954 18651412
MESH:D001321 Autistic Disorder Acetaminophen 2.2218445737
MESH:D001321 Autistic Disorder Glutathione 2.2218929414 16917939 19267885 19056591
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.831440618 11289319
MESH:D001778 Blood Coagulation Disorders Amiodarone 54.9819483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 54.9816206674
MESH:D001778 Blood Coagulation Disorders Benzbromarone 54.9819483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 54.9819483382
MESH:D001778 Blood Coagulation Disorders Ethionine 54.9819483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 54.9819483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 54.9819483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 54.9819483382
MESH:D001778 Blood Coagulation Disorders Thioacetamide 54.9819483382
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.2717474063
MESH:D016535 Bronchial Hyperreactivity Ozone 3.5319059883 16777450 14754758 18315731 17626835 15516495 18417511
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1511589617
MESH:D002056 Burns Ethanol 4.4616374292
MESH:D002100 Cachexia Ozone 4.5516183385
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 19.3016705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 19.3016705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 19.303581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 19.303084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 19.3014691202 16217749 15073043 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 19.301701930
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 19.3017138121 20007298 16540662 16288022 16807293 18393292 16502159 3581430 10737359 17761372 20084675 19701751 18665156 19335982 20727157 19822196 20935162 18210153 20514400 3084413 20512989 18506893 19418558 17173139 17978847 19052882 16830150 19919837 21159647 18788625 19539802 17055752 20214788 16779866 11831363 18785209 10672840 16698587 20432363 16878318 19394651 18494052 16328049 19519916 16681979 18691550 16935385 18978308 20524982 19208518 18056438 19171122 20101231 16569478 18971187 17162532 17428255 19107877 19383236
MESH:D006528 Carcinoma, Hepatocellular Ethanol 19.3015763234 18788625 15289165
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 19.3017997003
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.6819014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.597296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9512490120
MESH:D002294 Carcinoma, Squamous Cell Glutathione 3.3217015178
MESH:D006332 Cardiomegaly Ethanol 3.3319332462
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8315710769 19225199
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.8918974383
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 7.0514694615
MESH:D002386 Cataract Acetaminophen 7.0510977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 14.986135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 14.987505956
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 14.981399818
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 14.982727394 21159647 17174075 7505956
MESH:D002637 Chest Pain Omeprazole 4.9115447763
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.2019052882
MESH:D018281 Cholangiocarcinoma Thioacetamide 9.2018291259
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 7.389022650 19486331
MESH:D002779 Cholestasis pirinixic acid 7.3819176532
MESH:D002971 Cleft Lip Ethanol 3.4915513904
MESH:D002972 Cleft Palate Ethanol 3.1015513904
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 4.0015095906
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0012609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.8010525206
MESH:D019465 Craniofacial Abnormalities Ethanol 2.8015451039 15513904 15451040 11873399 10194807 19302082 11198716
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.2618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.2618551238
MESH:D003550 Cystic Fibrosis Glutathione 4.3219747007
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9215213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.6211298694 12868966 14531868 11906362 8970840 2524372 18759878 8156756
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3418249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.312952479 3621924
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.1520387270
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 32.3818551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 32.3821346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 32.3818692083 16192314 18289764 9328219 6482804 7440962 11289319 9022650 8291058 18648102 6679447 1440618 9653073
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 32.3821346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 32.382444490 14550746 19420014 12153990 12392966 11529661 19085960 19164858 16485898 12540782 16177239 18071297 16109766 11461765 16393943 16227642 16081117 11834606 10774834 19416960 15619225 10915739 19370779 11739529 19923254 10663392 12958197 18713872 17562736 14986274 12594235 19739265 12705907 11421492 17522070 17906064 15968718 16781746 11287661 14725611 11743745
MESH:D056486 Drug-Induced Liver Injury Amiodarone 32.3815265979 18218290
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 32.3817654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 32.3819107877
MESH:D056486 Drug-Induced Liver Injury Ethanol 32.3811566570
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 32.3816221962
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 32.3812963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9119426721
MESH:D004381 Duodenal Ulcer Omeprazole 4.1515991576 16613094 21218061 17151854
MESH:D050171 Dyslipidemias Clofibrate 3.9316707586
MESH:D004417 Dyspnea Chlorine 4.4320016425
MESH:D004487 Edema pirinixic acid 2.3112083418
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9216302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 10.033581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 10.0312903497
MESH:D004938 Esophageal Neoplasms Ethanol 10.0316704527
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 10.0315878914 16704527 15547733 15547721 15264214 15623463 16805852 15150132 16510608
MESH:D005218 Fat Necrosis Thioacetamide 5.5316456712
MESH:D005234 Fatty Liver Amiodarone 28.4814986274
MESH:D005234 Fatty Liver arsenic trioxide 28.4815073043
MESH:D005234 Fatty Liver Clofibrate 28.4819224547
MESH:D005234 Fatty Liver Diethylnitrosamine 28.4820387270 21071580
MESH:D005234 Fatty Liver Ethanol 28.4819236843 18620774 16409862
MESH:D005234 Fatty Liver pirinixic acid 28.4819236843 20131406
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.4717920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.1115513904 16946407 15451040 10194807
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.836705139
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0816904648
MESH:D005739 Gas Poisoning Chlorine 4.8220016425
MESH:D005756 Gastritis Acetaminophen 10.4816983495
MESH:D005756 Gastritis Ethanol 10.4815046732
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.867505956
MESH:D006333 Heart Failure pirinixic acid 2.4220558911
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.4017276928 18665440 15929193
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.846705139
MESH:D006505 Hepatitis Thioacetamide 8.8416456712
MESH:D006529 Hepatomegaly Amiodarone 13.5115265979
MESH:D006529 Hepatomegaly fumonisin B1 13.5116221962
MESH:D006529 Hepatomegaly pirinixic acid 13.5116221962 19176532 18467677 19772884
MESH:D006930 Hyperalgesia Acetaminophen 7.3116870215
MESH:D006930 Hyperalgesia Ethanol 7.3118783367
MESH:D006937 Hypercholesterolemia Amiodarone 3.709751232 8137927
MESH:D006943 Hyperglycemia pirinixic acid 3.0220558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.7515034207
MESH:D007037 Hypothyroidism Amiodarone 10.9817991464 18020914
MESH:D007037 Hypothyroidism Propylthiouracil 10.9818031379 8137927
MESH:D007249 Inflammation Diethylnitrosamine 2.2918785209
MESH:D007333 Insulin Resistance pirinixic acid 2.5116306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.838074119 9022650
MESH:D007569 Jaw Abnormalities Ethanol 4.2315513904
MESH:D007674 Kidney Diseases Acetaminophen 2.0915629191 12587719
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 11.5016705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 11.5016705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.506582329
MESH:D007859 Learning Disorders Ethanol 4.0215451040
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 3.9419248655
MESH:D007938 Leukemia arsenic trioxide 2.7415070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6212560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1116972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.2914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.5919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1116467208 16968895 17050201 19850784 20471514
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.099834237 19225113 16330433 12679006 15336539 19642359 15748426 16891316 16331271 19035177 12018890 16966277 16112521 17217047 11468182 17649720 17869043 12712474 15213294 11161223 16823087 19075265 17107899 17712046 15622746
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1716882451
MESH:D017880 Limb Deformities, Congenital Ethanol 3.6817676605
MESH:D008064 Lipidoses Amiodarone 3.3717567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.4718522880 18665156 19638242 20032147 18407596
MESH:D008103 Liver Cirrhosis Ethanol 6.4715289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.9018295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.0815034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 3.4918166357
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.4915474484
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 3.4916126171 18395095 12531686 16097051 15078482 16098781 15075984 16489207 18295389 12679928 17629604 15716488 11172339 12891558 18416461 12557150 15095483 18263696 18032466 15334695 17050028 12085344 15316131 18458672 11481614 15288472 15474484 14739098 17127702 17292413 11682029 12175628 18380797 10677585 16511523 17355460 15288473 16248980 18606216 15158331 15362042 18615449 16343077 18031379 15465738
MESH:D008107 Liver Diseases Acetaminophen 6.2616611625 12587719 19784758 12969438 16610002 19460945 11587558 19014921
MESH:D008107 Liver Diseases Diethylnitrosamine 6.2617034775
MESH:D008107 Liver Diseases Thioacetamide 6.2616337175 15158337 18374380
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.4617207112 17347304
MESH:D017114 Liver Failure, Acute Acetaminophen 9.0817185352 16871587
MESH:D017114 Liver Failure, Acute Thioacetamide 9.0812479984 15313186 17276928 15633222
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 13.477678174
MESH:D008113 Liver Neoplasms arsenic trioxide 13.4714682389
MESH:D008113 Liver Neoplasms Clofibric Acid 13.4717602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 13.4718978307 19833225 20118626 19499222 19294768 18754104 19850985 19426721 20434301 16942905 19551842 21278145 19256749 20452335 19642983 12771043 19254457 19812893 2422723 19638242 12112319 18644402 19255062 19427195 19996281 21047994 19073162 20137499 2862719 20405173 18977376 21071580 19090486 20583210 15885732 20101389 19690152 21167192 18648771 20492335 10737359 20501860 15175105 9163691
MESH:D008113 Liver Neoplasms pirinixic acid 13.4716377806 15890375 20007298
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 13.152876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 13.156587162 1399818 3712494 598648
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 13.1520377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.1518093689 17174075 18775883 19009564 18544905 16842330 18079962 19539802 19126423 17854601 3124819 2563599 17942915 18308698 18164116 19519916 19004024 18282651 18253720 9362446 21159647 16267830
MESH:D008133 Long QT Syndrome Amiodarone 7.7111989578 17391786 15350150
MESH:D008133 Long QT Syndrome arsenic trioxide 7.7115213294
MESH:D008171 Lung Diseases Amiodarone 7.1712587719
MESH:D008171 Lung Diseases Ozone 7.1719066396 8266340
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.2918516814
MESH:D055370 Lung Injury Ozone 3.6620417186
MESH:D008175 Lung Neoplasms arsenic trioxide 3.3811798837 19825857
MESH:D008175 Lung Neoplasms Diethylnitrosamine 3.3820970405 21163286 6695378 20512841
MESH:D008175 Lung Neoplasms Ozone 3.387614698 8597069
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3819513568
MESH:D008569 Memory Disorders Ethanol 4.0018411066 15451040
MESH:D008679 Metaplasia Ozone 4.9110496685
MESH:D009101 Multiple Myeloma arsenic trioxide 2.9715949261 19549372 19417148 11468182 14977855
MESH:D009135 Muscular Diseases pirinixic acid 3.3216239165
MESH:D009181 Mycoses Amiodarone 4.7117974566 12754197
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.4818349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0316105982 16882451
MESH:D009203 Myocardial Infarction pirinixic acid 2.0719151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8016411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.7118551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.717678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7816624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.453581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.453581430 9029167
MESH:D009369 Neoplasms pirinixic acid 1.8617405874
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 6.846679447
MESH:D009436 Neural Tube Defects arsenic trioxide 6.8410525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.6618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.6620387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9220387270
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.759802331
MESH:D009765 Obesity pirinixic acid 1.7720558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 20.2116049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 20.2116049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 20.216482804 4026338
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 20.2114694615
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.833988306
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.3516624393 19769630 12452020
MESH:D010146 Pain Acetaminophen 2.2416870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.2815580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.2816540662
MESH:D010190 Pancreatic Neoplasms Ethanol 8.2812384795
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.307296757
MESH:D010235 Paraganglioma arsenic trioxide 3.9819927285
MESH:D010538 Peritonitis Ozone 3.9416369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.286228378
MESH:D011014 Pneumonia Ozone 4.2018381685 18929643 18007984
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.392563599
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.3319131511
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.7812832656 11597910 12490602
MESH:D015427 Reperfusion Injury pirinixic acid 2.2919058328
MESH:D012120 Respiration Disorders Chlorine 5.0218579056
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.233692021
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.7816646077
MESH:D012640 Seizures 2,4-dinitrotoluene 9.1318551238
MESH:D012640 Seizures 2,6-dinitrotoluene 9.1318551238
MESH:D012640 Seizures Ethanol 9.139754883
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.8918724381
MESH:D013272 Stomach Diseases Omeprazole 4.4218545984
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.6117007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.6118456281
MESH:D013274 Stomach Neoplasms Ethanol 4.6118456281
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 4.6112958204 17575124
MESH:D013276 Stomach Ulcer Amiodarone 11.2118087811
MESH:D013276 Stomach Ulcer Ethanol 11.219562338 11906479 17189318 17918041 16755016 9211565
MESH:D013276 Stomach Ulcer Omeprazole 11.2118237397 16755016 11906479 10750652 17977527 15991576
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.099754883
MESH:D013610 Tachycardia Amiodarone 4.1111238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.0119225199
MESH:D013959 Thyroid Diseases Amiodarone 4.5719731979
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 15.946587162 3712494 1399818 7505956 6582329
MESH:D013964 Thyroid Neoplasms arsenic trioxide 15.9419014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 15.947505956
MESH:D013964 Thyroid Neoplasms Propylthiouracil 15.9415710170
MESH:D013971 Thyrotoxicosis Amiodarone 4.6719584973 18020914
MESH:D016171 Torsades de Pointes Amiodarone 9.6217467628 11989578
MESH:D016171 Torsades de Pointes arsenic trioxide 9.6215213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 11.3016049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.3016049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 11.308074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 11.3012845720 11780464 20435036 12973940
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.3510091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.3510091137
MESH:D014581 Urticaria Acetaminophen 2.8010982225
Pathway ID Pathway Name
KEGG:04110 Cell cycle
REACT:152 Cell Cycle, Mitotic
KEGG:04722 Neurotrophin signaling pathway
KEGG:04114 Oocyte meiosis
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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