AutismKB 2.0

Annotation Detail for ZNF12


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Basic Information Top
Gene Symbol:ZNF12 ( GIOT-3,HZF11,KOX3,ZNF325 )
Gene Full Name: zinc finger protein 12
Band: 7p22.1
Quick LinksEntrez ID:7559; OMIM: 194536; Uniprot ID:ZNF12_HUMAN; ENSEMBL ID: ENSG00000164631; HGNC ID: 12902
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZNF12 mRNAdecreases expression 20018196
D012643 Selenium [Selenium co-treated with Vitamin E] results in decreased expression of ZNF12 mRNAaffects cotreatment|decreases expression 19244175
D012643 Selenium Selenium results in decreased expression of ZNF12 mRNAdecreases expression 19244175
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in decreased expression of ZNF12 mRNAaffects cotreatment|decreases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of ZNF12 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.5816050911
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0120889678
MESH:D003092 Colitis Selenium 4.4317936198
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9319769572
MESH:D056486 Drug-Induced Liver Injury Selenium 2.2615131321
MESH:C538011 Eales disease Vitamin E 5.579068938
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1816080930
MESH:D006333 Heart Failure Selenium 3.3217162251
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8216863852 16490937
MESH:D019584 Hot Flashes Vitamin E 4.8414716179
MESH:D007251 Influenza, Human Selenium 14.0716624496
MESH:D007251 Influenza, Human Vitamin E 14.0716624496
MESH:D007674 Kidney Diseases Vitamin E 3.0312488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.3716518626
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9116169303
MESH:D008171 Lung Diseases Vitamin E 3.4516863852
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D008325 Mammary Neoplasms, Experimental Selenium 3.0215318939
MESH:D008654 Mesothelioma Selenium 2.9315107826
MESH:D010954 Plasmacytoma Selenium 5.7615087411
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2415084515
MESH:D012871 Skin Diseases Vitamin E 2.5218709164
MESH:D020521 Stroke Vitamin E 3.8816517955
Pathway ID Pathway Name
REACT:71 Gene Expression
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018