Annotation Detail for ZNF32
Basic Information Top
| Gene Symbol: | ZNF32 ( KOX30 ) |
|---|---|
| Gene Full Name: | zinc finger protein 32 |
| Band: | 10q11.21 |
| Quick Links | Entrez ID:7580; OMIM: 194539; Uniprot ID:ZNF32_HUMAN; ENSEMBL ID: ENSG00000169740; HGNC ID: 13095 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D005047 | Etoposide | ZNF32 protein affects the susceptibility to Etoposide | affects response to substance | 16217747 |
| D005472 | Fluorouracil | ZNF32 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] | affects cotreatment|increases response to substance | 17327601 |
| D002955 | Leucovorin | ZNF32 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] | affects cotreatment|increases response to substance | 17327601 |
| C051890 | irinotecan | ZNF32 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] | affects cotreatment|increases response to substance | 17327601 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000230 | Adenocarcinoma | Fluorouracil | 2.50 | 17638652 | |
| MESH:D000740 | Anemia | Fluorouracil | 4.11 | 16511603 15504547 17963324 | |
| MESH:D019046 | Bone Marrow Neoplasms | Etoposide | 5.88 | 14601052 | |
| MESH:D001943 | Breast Neoplasms | Etoposide | 2.53 | 16322251 | |
| MESH:D001943 | Breast Neoplasms | Fluorouracil | 2.53 | 16110121 16557594 18357371 15136595 18608205 19217205 16595493 | |
| MESH:D002276 | Carcinoid Tumor | Fluorouracil | 5.39 | 16051944 | |
| MESH:D002277 | Carcinoma | Fluorouracil | 3.89 | 17121937 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Fluorouracil | 2.12 | 17045692 17088986 16332177 17971768 16799960 18930000 | |
| MESH:D002292 | Carcinoma, Renal Cell | Fluorouracil | 3.17 | 18695887 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Fluorouracil | 2.58 | 16757204 17066447 18986760 16280240 | |
| MESH:D003110 | Colonic Neoplasms | Fluorouracil | 4.15 | 17287894 15001691 16340194 17016597 17172411 17169374 16510598 18772588 17018589 17725105 | |
| MESH:D003110 | Colonic Neoplasms | irinotecan | 4.15 | 17287894 17725105 | |
| MESH:D015179 | Colorectal Neoplasms | Fluorouracil | 3.88 | 20501625 17594712 16391804 17695437 18448328 18802399 18949393 15148649 16524972 17255274 17016601 18383874 17454858 18288408 16282729 18509181 16303861 17401013 14970324 17094418 16331619 15289873 | |
| MESH:D015179 | Colorectal Neoplasms | irinotecan | 3.88 | 18259882 17454858 17159606 16303861 16391804 15273666 18509181 | |
| MESH:D015179 | Colorectal Neoplasms | Leucovorin | 3.88 | 17401013 20501625 17255274 17454858 16303861 17594712 | |
| MESH:D019465 | Craniofacial Abnormalities | Leucovorin | 3.57 | 16925845 | |
| MESH:D007644 | Darier Disease | Fluorouracil | 5.42 | 16733453 | |
| MESH:D004938 | Esophageal Neoplasms | Fluorouracil | 2.52 | 16785472 16337965 15173087 16481741 17638652 | |
| MESH:D005910 | Glioma | Fluorouracil | 2.99 | 16145905 | |
| MESH:D006258 | Head and Neck Neoplasms | Fluorouracil | 3.64 | 15162350 18337622 15102660 | |
| MESH:D006561 | Herpes Simplex | Etoposide | 5.19 | 10809021 | |
| MESH:D006689 | Hodgkin Disease | Etoposide | 4.23 | 16135485 17606976 15147373 16200630 18180244 | |
| MESH:D007680 | Kidney Neoplasms | Fluorouracil | 3.65 | 16985049 | |
| MESH:D008113 | Liver Neoplasms | Fluorouracil | 2.60 | 16603448 15113037 18383874 17045692 | |
| MESH:D008175 | Lung Neoplasms | Fluorouracil | 2.01 | 15246190 | |
| MESH:D008178 | Lupus Erythematosus, Cutaneous | Fluorouracil | 5.42 | 15086387 | |
| MESH:D008223 | Lymphoma | Etoposide | 4.20 | 12556972 12854902 | |
| MESH:D009062 | Mouth Neoplasms | Fluorouracil | 3.94 | 16757204 18986760 | |
| MESH:D052016 | Mucositis | irinotecan | 5.64 | 17159606 | |
| MESH:D009362 | Neoplasm Metastasis | irinotecan | 3.30 | 18259882 | |
| MESH:D009369 | Neoplasms | Fluorouracil | 2.77 | 18600527 18239605 16928823 | |
| MESH:D009447 | Neuroblastoma | irinotecan | 3.65 | 8761367 | |
| MESH:D017599 | Neuroectodermal Tumors | irinotecan | 5.36 | 8761367 | |
| MESH:D020258 | Neurotoxicity Syndromes | Fluorouracil | 3.69 | 16436463 | |
| MESH:D010190 | Pancreatic Neoplasms | Etoposide | 6.02 | 19003803 | |
| MESH:D010190 | Pancreatic Neoplasms | Fluorouracil | 6.02 | 16500647 16929163 15113037 19003803 | |
| MESH:D011471 | Prostatic Neoplasms | Etoposide | 3.53 | 17172428 | |
| MESH:D011471 | Prostatic Neoplasms | Fluorouracil | 3.53 | 19082440 18626508 | |
| MESH:D012004 | Rectal Neoplasms | Fluorouracil | 4.38 | 18722050 15538739 18286688 16160472 | |
| MESH:D015427 | Reperfusion Injury | Leucovorin | 4.75 | 17295595 | |
| MESH:D012512 | Sarcoma, Ewing's | Etoposide | 5.21 | 14601052 | |
| MESH:D013274 | Stomach Neoplasms | Fluorouracil | 2.79 | 16424979 16951190 18396642 19015929 17498489 18567086 17522103 17172411 15786421 19084572 | |
| MESH:D013274 | Stomach Neoplasms | irinotecan | 2.79 | 15723263 | |
| MESH:D014062 | Tongue Neoplasms | Fluorouracil | 4.38 | 16280240 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Fluorouracil | 4.27 | 16803524 |
| No data |