AutismKB 2.0

Annotation Detail for ZNF33B


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Basic Information Top
Gene Symbol:ZNF33B ( FLJ23327,KOX2,KOX31,MGC129696,ZNF11B )
Gene Full Name: zinc finger protein 33B
Band: 10q11.21
Quick LinksEntrez ID:7582; OMIM: 194522; Uniprot ID:ZN33B_HUMAN; ENSEMBL ID: ENSG00000196693; HGNC ID: 13097
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006632 arsenic trioxide arsenic trioxide results in decreased expression of ZNF33B mRNAdecreases expression 20458559
C059514 resveratrol resveratrol results in decreased expression of ZNF33B mRNAdecreases expression 19371625
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D058186 Acute Kidney Injury resveratrol 4.4016538975
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3719825857 11798837
MESH:D000236 Adenoma resveratrol 3.5615688382
MESH:D000544 Alzheimer Disease resveratrol 2.6416162502 16183991
MESH:D001169 Arthritis, Experimental resveratrol 3.7717115116
MESH:D050197 Atherosclerosis resveratrol 3.5316873680 17967414
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.2216206674
MESH:D002545 Brain Ischemia resveratrol 5.1717600658
MESH:D001943 Breast Neoplasms resveratrol 2.6517651959 17534123 16393696
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.9411589617
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 3.4011135700 16217749 14691202 15073043 15553829
MESH:D006528 Carcinoma, Hepatocellular resveratrol 3.4019321006 16227395
MESH:D018827 Carcinoma, Lewis Lung resveratrol 5.4816675471
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.9419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.6312490120
MESH:D002294 Carcinoma, Squamous Cell resveratrol 2.8116227395
MESH:D002318 Cardiovascular Diseases resveratrol 3.8015458977
MESH:D003092 Colitis resveratrol 4.8916474422
MESH:D003110 Colonic Neoplasms resveratrol 2.5116338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.7120501625
MESH:D015179 Colorectal Neoplasms resveratrol 2.7116550006
MESH:D003327 Coronary Disease resveratrol 4.0416507316
MESH:D023903 Coronary Restenosis arsenic trioxide 4.8612609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.9010525206
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.7015213294
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 4.2016873680
MESH:D003928 Diabetic Nephropathies resveratrol 4.4316286809
MESH:D004487 Edema resveratrol 3.918985016
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 4.7017872969
MESH:D020345 Enterocolitis, Necrotizing resveratrol 5.6117923197
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.4012903497
MESH:D005234 Fatty Liver arsenic trioxide 3.8415073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.9416904648
MESH:D006561 Herpes Simplex resveratrol 5.0616876885
MESH:D006937 Hypercholesterolemia resveratrol 4.5617188708
MESH:D006949 Hyperlipidemias resveratrol 4.6316873680
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.8117488730
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 5.4117600658
MESH:D007249 Inflammation resveratrol 3.0516366677
MESH:D007251 Influenza, Human resveratrol 5.6116624496
MESH:D007938 Leukemia arsenic trioxide 3.0315070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.3517077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 5.1916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.3119077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1917050201 16968895 20471514 16467208 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 8.7911161223 15748426 15622746 12712474 19075265 15336539 11468182 16331271 16966277 17107899 19225113 19642359 16112521 16330433 12679006 17712046 17869043 17217047 19035177 12018890 9834237 17649720 16823087 15213294 16891316
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 8.7916087638
MESH:D015458 Leukemia, T-Cell arsenic trioxide 5.0316882451
MESH:D008113 Liver Neoplasms arsenic trioxide 5.2914682389
MESH:D008113 Liver Neoplasms resveratrol 5.2919812893 19321006 20405173 19073162
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 3.0120377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.7315213294
MESH:D008175 Lung Neoplasms arsenic trioxide 1.8719825857 11798837
MESH:D016393 Lymphoma, B-Cell resveratrol 4.9117088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 4.3114749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 5.1315688416
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 3.4011606380 8985016
MESH:D008545 Melanoma resveratrol 2.4117992120
MESH:D008659 Metabolic Diseases resveratrol 4.9317112576
MESH:D009101 Multiple Myeloma arsenic trioxide 8.5811468182 14977855 19549372 15949261 19417148
MESH:D009101 Multiple Myeloma resveratrol 8.5816267019 14749477 17164350 16490592 17935668 17049120
MESH:D009134 Muscular Atrophy, Spinal resveratrol 5.7617962980
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.7418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3816105982 16882451
MESH:D009203 Myocardial Infarction resveratrol 3.1916456233 16317513 17015251 16525036 17125593 17188708
MESH:D017202 Myocardial Ischemia resveratrol 4.4217015251 17125593
MESH:D009205 Myocarditis resveratrol 5.6517322642
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.6316624393
MESH:D009374 Neoplasms, Experimental resveratrol 4.768985016
MESH:D009436 Neural Tube Defects arsenic trioxide 3.4110525206
MESH:D019636 Neurodegenerative Diseases resveratrol 4.2417652729
MESH:D020078 Neurogenic Inflammation resveratrol 5.0117929310
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.8617513867
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.5216624393 12452020 19769630
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6615580305
MESH:D010235 Paraganglioma arsenic trioxide 4.7719927285
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 5.0616679765
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.3219131511
MESH:D011471 Prostatic Neoplasms resveratrol 3.3217636462 16731767 17804756 17718901 15767336 17675339
MESH:D051436 Renal Insufficiency, Chronic resveratrol 6.6516325855
MESH:D015427 Reperfusion Injury resveratrol 3.4716317513 15827377 17058453 16314181 17520802
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.6316646077
MESH:D012878 Skin Neoplasms resveratrol 3.2215837718 8985016
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.9916321402
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.4719014326
MESH:D014062 Tongue Neoplasms resveratrol 4.7216227395
MESH:D016171 Torsades de Pointes arsenic trioxide 4.8515213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.6212973940 12845720 11780464 20435036
MESH:D002583 Uterine Cervical Neoplasms resveratrol 4.6117473185
MESH:D014594 Uterine Neoplasms resveratrol 4.8117044934
MESH:D018487 Ventricular Dysfunction, Left resveratrol 5.0617488730
Pathway ID Pathway Name
REACT:71 Gene Expression
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018