AutismKB 2.0

Annotation Detail for ZNF131


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZNF131 ( pHZ-10 )
Gene Full Name: zinc finger protein 131
Band: 5p12
Quick LinksEntrez ID:7690; OMIM: 604073; Uniprot ID:ZN131_HUMAN; ENSEMBL ID: ENSG00000172262; HGNC ID: 12915
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of ZNF131 mRNAdecreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZNF131 mRNAdecreases expression 20018196
19150397
D016572 Cyclosporine Cyclosporine results in increased expression of ZNF131 mRNAincreases expression 20106945
D012643 Selenium Selenium results in decreased expression of ZNF131 mRNAdecreases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of ZNF131 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0520127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.846695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.5619183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0017474063 20146248
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.4116050911
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.3520889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.3512371664
MESH:D002779 Cholestasis Cyclosporine 3.1719486331
MESH:D003092 Colitis Selenium 4.2617936198
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D056486 Drug-Induced Liver Injury Selenium 2.2515131321
MESH:C538011 Eales disease Vitamin E 5.329068938
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.5920426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.5916530937
MESH:D005234 Fatty Liver Cyclosporine 3.2319224547
MESH:D005355 Fibrosis Cyclosporine 3.6212168785 12639820
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.768708960
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 7.2320471113
MESH:D006330 Heart Defects, Congenital Vitamin E 7.2316080930
MESH:D006333 Heart Failure Selenium 3.2717162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.9615720958
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8016863852 16490937
MESH:D019584 Hot Flashes Vitamin E 4.5814716179
MESH:D006973 Hypertension Cyclosporine 2.2010903974
MESH:D007251 Influenza, Human Selenium 13.0916624496
MESH:D007251 Influenza, Human Vitamin E 13.0916624496
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.0515604871
MESH:D007674 Kidney Diseases Cyclosporine 6.6318776723 10903974 8314463
MESH:D007674 Kidney Diseases Vitamin E 6.6312488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.2616518626
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0412371664
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9016169303
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1420195826 21137059
MESH:D008171 Lung Diseases Vitamin E 3.4016863852
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.5020464547 20064080 17053015 20869020 18816296 18569708 18520028 6695378 20135361
MESH:D008175 Lung Neoplasms Vitamin E 2.5011062179
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.9715318939
MESH:D008654 Mesothelioma Selenium 2.9015107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.4016801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4616381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3111141357
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.0517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6119348381 18481113
MESH:D010954 Plasmacytoma Selenium 5.5015087411
MESH:D011230 Precancerous Conditions Cyclosporine 3.5512371664
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.1117292933
MESH:D011471 Prostatic Neoplasms Vitamin E 3.1115084515
MESH:D011565 Psoriasis Cyclosporine 2.3216882103
MESH:D012871 Skin Diseases Vitamin E 2.5118709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5110029692 19755658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D020521 Stroke Vitamin E 3.8116517955
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2917053015
MESH:D014605 Uveitis Cyclosporine 4.591336536
MESH:D014985 Xerophthalmia Cyclosporine 5.0517120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved