AutismKB 2.0

Annotation Detail for ZFAND5


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Basic Information Top
Gene Symbol:ZFAND5 ( ZA20D2,ZFAND5A,ZNF216 )
Gene Full Name: zinc finger, AN1-type domain 5
Band: 9q21.13
Quick LinksEntrez ID:7763; OMIM: 604761; Uniprot ID:ZFAN5_HUMAN; ENSEMBL ID: ENSG00000107372; HGNC ID: 13008
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200091FoxO family signaling
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of ZFAND5 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased expression of ZFAND5 mRNAincreases expression 11264010
C109238 acyline acyline results in increased expression of ZFAND5 mRNAincreases expression 17510436
C006632 arsenic trioxide arsenic trioxide results in increased expression of ZFAND5 mRNAincreases expression 20458559
D001554 Benzene Benzene results in decreased expression of ZFAND5 mRNAdecreases expression 15120971
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of ZFAND5 mRNAincreases expression 17879257
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZFAND5 mRNAdecreases expression 19150397
C006780 bisphenol A bisphenol A results in decreased expression of ZFAND5 mRNAdecreases expression 20678512
D016572 Cyclosporine Cyclosporine results in increased expression of ZFAND5 mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of ZFAND5 mRNAdecreases expression 18042831
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ZFAND5 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of ZFAND5 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZFAND5 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of ZFAND5 mRNAdecreases expression 17108234
C041786 palm oil palm oil results in decreased expression of ZFAND5 mRNAdecreases expression 18042831
C006253 pirinixic acid pirinixic acid results in increased expression of ZFAND5 mRNAincreases expression 18301758
C059514 resveratrol resveratrol results in decreased expression of ZFAND5 mRNAdecreases expression 12569576
C017947 sodium arsenite sodium arsenite results in increased expression of ZFAND5 mRNAincreases expression 16014739
D013629 Tamoxifen Tamoxifen affects the expression of ZFAND5 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZFAND5 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ZFAND5 mRNAincreases expression 17942748
D014635 Valproic Acid Valproic Acid results in decreased expression of ZFAND5 mRNAdecreases expression 19101580
D014810 Vitamin E Vitamin E results in decreased expression of ZFAND5 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.5214745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.1911752688 14514962 15322242
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 8.198875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.8919490988
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9117505938
MESH:D058186 Acute Kidney Injury resveratrol 3.8116538975
MESH:D055371 Acute Lung Injury pirinixic acid 3.0818653653
MESH:D000230 Adenocarcinoma arsenic trioxide 6.9619825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 6.9620127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.9614692618
MESH:D000236 Adenoma Benzo(a)pyrene 6.726695378
MESH:D000236 Adenoma resveratrol 6.7215688382
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.7816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.7816835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.6715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.8717306315 16712894
MESH:D000544 Alzheimer Disease resveratrol 2.5616183991 16162502
MESH:D000550 Amblyopia Valproic Acid 5.2017688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9111748828
MESH:D000741 Anemia, Aplastic Benzene 4.3311369114 17661222 14761424
MESH:D000799 Angioedema Acetaminophen 3.8110982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.5417497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0319183758
MESH:D001161 Arteriosclerosis Dietary Fats 9.7815238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.7811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.2715885639
MESH:D001169 Arthritis, Experimental resveratrol 7.2717115116
MESH:D050197 Atherosclerosis resveratrol 3.2516873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8517688650 19232924 17157402 18775368 19460635 16609825 20603192 17507914 18396377 18940202 15238991 18316065 18177632 18985861 18558336
MESH:D001714 Bipolar Disorder Valproic Acid 3.0520046352 17594078
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 15.0516206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.0519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.0512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.9315746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.938888407
MESH:D001855 Bone Marrow Diseases Benzene 5.2016183116
MESH:D001862 Bone Resorption bisphenol A 3.8211985600
MESH:D002545 Brain Ischemia resveratrol 4.2517600658
MESH:D001943 Breast Neoplasms Benzene 3.7517162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.7520146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 3.7517123778
MESH:D001943 Breast Neoplasms Dietary Fats 3.7520435547
MESH:D001943 Breast Neoplasms resveratrol 3.7517651959 17534123 16393696
MESH:D001943 Breast Neoplasms Tamoxifen 3.7518351453 20065188 19244106 19155303 18984771 17261762 19103187 15668708 18425577 15565566 19289846 16818667 20005174 18629630 17242785 19288272 20135344 19221464 19059307 18855134 16273361 18821012 11161223 20544844 19066611 20390343 17893378 20859285 19084267 19011961 19410462 16873071 21138602 18997820 17440819 17049068 18815881 19142967 19487384 21152245 19200415 19189212 19189210 19115204 16202921
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.7520435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2911589617
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8916050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4719066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.803084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 8.8014691202 15553829 15073043 11135700 16217749
MESH:D006528 Carcinoma, Hepatocellular resveratrol 8.8016227395 19321006
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 8.8015276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.8016924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.9517123778
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.5616675471
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.8519014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0812490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.5020419170
MESH:D002294 Carcinoma, Squamous Cell resveratrol 7.5016227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 7.5018572023
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5717572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3418850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases resveratrol 3.4415458977
MESH:D002386 Cataract Acetaminophen 2.5510977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.9920889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.9912371664
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 10.9920056578 19524636
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6920734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1216835633
MESH:D002779 Cholestasis Cyclosporine 13.1519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.1515861022 16105132 17333356 11677210 17110522 17681005 16919318
MESH:D002779 Cholestasis pirinixic acid 13.1519176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0815668235 15340226 12621046 16354765 8697196
MESH:D003092 Colitis resveratrol 4.0916474422
MESH:D003110 Colonic Neoplasms resveratrol 2.4516338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.6220501625
MESH:D015179 Colorectal Neoplasms resveratrol 2.6216550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0217141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.7216507316
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1412609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 7.2910525206
MESH:D019465 Craniofacial Abnormalities Benzene 7.2915643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 7.2920055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Valproic Acid 7.2917688650 16575769 8888407
MESH:D019465 Craniofacial Abnormalities Vitamin E 7.2919769572
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0515213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3219031437
MESH:D003872 Dermatitis Benzene 4.7315902427
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4018249437
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.7316873680
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6617107852
MESH:D003928 Diabetic Nephropathies resveratrol 8.9116286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.9119279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.0719923254 16781746 19420014 11834606 16109766 14725611 10774834 11461765 12958197 18071297 16177239 10663392 16393943 19416960 12392966 12540782 16081117 11739529 19370779 19739265 16485898 18713872 19085960 17906064 2444490 14986274 17562736 11529661 15619225 11743745 11287661 19164858 10915739 14550746 15968718 11421492 17522070 12594235 12705907 12153990 16227642
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.0720420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 6.0719641884 1733752
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7311462148
MESH:D050171 Dyslipidemias Dietary Fats 3.4218367378
MESH:D004421 Dystonia Valproic Acid 4.011851702
MESH:C538011 Eales disease Vitamin E 4.689068938
MESH:D004487 Edema pirinixic acid 11.2012083418
MESH:D004487 Edema resveratrol 11.208985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.2011000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8718230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.1212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 15.1217872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.1219031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.0217893378 16202921 20544844 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.989294722 10568697
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.8117923197
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.1117275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 3.893922381 16628512
MESH:D004827 Epilepsy Valproic Acid 2.9118234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.557562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.267750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.033659116
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.1520426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 7.1512903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.1516530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9811564622
MESH:D005234 Fatty Liver arsenic trioxide 36.4315073043
MESH:D005234 Fatty Liver Cyclosporine 36.4319224547
MESH:D005234 Fatty Liver Dietary Fats 36.4317967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 36.4315345470
MESH:D005234 Fatty Liver pirinixic acid 36.4319236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 36.4319224547 14986274
MESH:D005234 Fatty Liver Valproic Acid 36.4314986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4211858732
MESH:D005315 Fetal Diseases Valproic Acid 4.8616575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.098888407 18558336
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4914745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.1519069698
MESH:D005355 Fibrosis Cyclosporine 14.5012639820 12168785
MESH:D005355 Fibrosis Dietary Fats 14.5018296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.5020067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.2216904648
MESH:D005756 Gastritis Acetaminophen 3.6516983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.6416452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.188708960
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5710696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.9720471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.9711294989 10048152
MESH:D006330 Heart Defects, Congenital Vitamin E 10.9716080930
MESH:D006333 Heart Failure pirinixic acid 2.5120558911
MESH:D006402 Hematologic Diseases Benzene 4.6116183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2911000095
MESH:D006529 Hepatomegaly pirinixic acid 8.1319176532 18467677 16221962 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.1316120746 12621046 15340226
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6916490937 16863852
MESH:D006561 Herpes Simplex resveratrol 4.1416876885
MESH:D006689 Hodgkin Disease sodium arsenite 3.1112676792
MESH:D019584 Hot Flashes Vitamin E 3.9414716179
MESH:D006849 Hydrocephalus Valproic Acid 4.8317688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0215340226 8697196 18606429 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 2.6616870215
MESH:D006937 Hypercholesterolemia Dietary Fats 9.0821332399
MESH:D006937 Hypercholesterolemia resveratrol 9.0817188708
MESH:D006943 Hyperglycemia pirinixic acid 3.1420558911
MESH:D006949 Hyperlipidemias Dietary Fats 9.1521332399
MESH:D006949 Hyperlipidemias resveratrol 9.1516873680
MESH:D006973 Hypertension Benzene 8.5117940673
MESH:D006973 Hypertension Cyclosporine 8.5110903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.5118670907 18850075
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.2617488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7716945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.6117600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.5417937319
MESH:D007248 Infertility, Male sodium arsenite 6.5415346721 12646999
MESH:D007249 Inflammation Dietary Fats 11.7820412841
MESH:D007249 Inflammation resveratrol 11.7816366677
MESH:D007249 Inflammation Tamoxifen 11.7819457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.7812878042 12200463
MESH:D007251 Influenza, Human resveratrol 10.9916624496
MESH:D007251 Influenza, Human Vitamin E 10.9916624496
MESH:D007333 Insulin Resistance bisphenol A 12.1716393666
MESH:D007333 Insulin Resistance Dietary Fats 12.1718457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 12.1716306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2916580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4115604871
MESH:D007674 Kidney Diseases Acetaminophen 14.2212587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 14.2218776723 10903974 8314463
MESH:D007674 Kidney Diseases sodium arsenite 14.2220008137
MESH:D007674 Kidney Diseases Vitamin E 14.2212488133
MESH:D007680 Kidney Neoplasms Cyclosporine 7.1712371664
MESH:D007680 Kidney Neoplasms Tamoxifen 7.1718625569
MESH:D007938 Leukemia arsenic trioxide 6.5015070760
MESH:D007938 Leukemia Benzene 6.5018335105 14694614 17119257 15935818
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.7517077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2716972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.5719077051
MESH:D007951 Leukemia, Myeloid Benzene 9.5717506065
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 6.1619850784 20471514 16968895 16467208 17050201
MESH:D015470 Leukemia, Myeloid, Acute Benzene 6.1619478238
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 6.1616294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.6915622746 17217047 17712046 11468182 19035177 15336539 17869043 16331271 16966277 15748426 15213294 12018890 12679006 9834237 19225113 16112521 17107899 16330433 12712474 17649720 19642359 11161223 16891316 16823087 19075265
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 7.6916087638
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.3116882451
MESH:D008064 Lipidoses Tamoxifen 3.1217567588 15342952
MESH:D008103 Liver Cirrhosis Dietary Fats 2.8518296743
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.8815474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.8818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8812878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.8816169303
MESH:D008107 Liver Diseases Acetaminophen 1.6216611625 19784758 12587719 19014921 12969438 19460945 16610002 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2016871587 17185352
MESH:D008113 Liver Neoplasms arsenic trioxide 21.6714682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 21.6720195826 21137059
MESH:D008113 Liver Neoplasms pirinixic acid 21.6716377806 15890375 20007298
MESH:D008113 Liver Neoplasms resveratrol 21.6719321006 20405173 19812893 19073162
MESH:D008113 Liver Neoplasms sodium arsenite 21.6716712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 21.6716684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 21.6716984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 9.7420377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 9.7412562636
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.7412151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3115213294
MESH:D008171 Lung Diseases sodium arsenite 7.3419095001
MESH:D008171 Lung Diseases Vitamin E 7.3416863852
MESH:D017563 Lung Diseases, Interstitial Benzene 11.2914698565
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 11.2917228818
MESH:D008175 Lung Neoplasms arsenic trioxide 10.6411798837 19825857
MESH:D008175 Lung Neoplasms Benzene 10.6412562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 10.6417053015 6695378 20464547 18569708 20135361 18816296 18520028 20869020 20064080
MESH:D008175 Lung Neoplasms sodium arsenite 10.6419931552 17306315 16712894 15276417 17077188
MESH:D008175 Lung Neoplasms Tamoxifen 10.6418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.6419555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 10.6411062179
MESH:D008223 Lymphoma Benzene 3.7017119257 17584886
MESH:D016393 Lymphoma, B-Cell resveratrol 4.2617088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.8314749477
MESH:D015674 Mammary Neoplasms, Animal Benzene 16.6212562636
MESH:D015674 Mammary Neoplasms, Animal resveratrol 16.6215688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 16.6219428831
MESH:D008325 Mammary Neoplasms, Experimental Benzene 9.9411921183
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 9.948985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 9.9419196722 14580682 16827153 11731420 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.5219453300
MESH:D008545 Melanoma resveratrol 5.1117992120
MESH:D008545 Melanoma sodium arsenite 5.1116487513 19082730
MESH:D008545 Melanoma Tamoxifen 5.1119393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1515990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5319513568
MESH:D008659 Metabolic Diseases resveratrol 4.3417112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7616801185
MESH:D008881 Migraine Disorders Valproic Acid 3.1618765137 18803445
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1516381670
MESH:D009101 Multiple Myeloma arsenic trioxide 12.0414977855 19549372 19417148 11468182 15949261
MESH:D009101 Multiple Myeloma Benzene 12.0417119195
MESH:D009101 Multiple Myeloma resveratrol 12.0416267019 17049120 14749477 17164350 17935668 16490592
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.8317962980
MESH:D009135 Muscular Diseases pirinixic acid 3.4716239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.998888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.6418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.3316882451 16105982
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 7.3317596541
MESH:D009203 Myocardial Infarction pirinixic acid 5.6819151258
MESH:D009203 Myocardial Infarction resveratrol 5.6817188708 16317513 16525036 17015251 16456233 17125593
MESH:D017202 Myocardial Ischemia resveratrol 8.8917015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.8912213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9116411023
MESH:D009205 Myocarditis resveratrol 4.7217322642
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.9216624393
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5019410462
MESH:D009369 Neoplasms Benzo(a)pyrene 8.0811141357
MESH:D009369 Neoplasms pirinixic acid 8.0817405874
MESH:D009369 Neoplasms sodium arsenite 8.0811559025
MESH:D009374 Neoplasms, Experimental resveratrol 9.108985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 9.1020056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.9719189210 19200415 19196722
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2418481113 19348381
MESH:D009421 Nervous System Malformations bisphenol A 9.4516427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.4514600291
MESH:D009436 Neural Tube Defects arsenic trioxide 17.1310525206
MESH:D009436 Neural Tube Defects Benzene 17.1315643154
MESH:D009436 Neural Tube Defects sodium arsenite 17.1312854658
MESH:D009436 Neural Tube Defects Valproic Acid 17.138888407 16359493
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.2318514411
MESH:D019636 Neurodegenerative Diseases resveratrol 8.2317652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.3617929310
MESH:D009765 Obesity Dietary Fats 4.4020132043 18674790 20518802 21332399 11836018 17217161 16723640 18457598 19632207
MESH:D009765 Obesity pirinixic acid 4.4020558911
MESH:D009784 Occupational Diseases Benzene 4.1415913788 17178637 16737584 17119257 15935809 15576619 17479406 15727169 15612468
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.2117513867
MESH:D010049 Ovarian Diseases bisphenol A 4.9511985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 7.9116624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Benzene 7.9112562636
MESH:D010051 Ovarian Neoplasms sodium arsenite 7.9115276417 17306315
MESH:D010146 Pain Acetaminophen 2.3516870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.5115580305
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6511578682
MESH:D010235 Paraganglioma arsenic trioxide 4.1219927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5218163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.1812371664
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 22.9810548101
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 22.9816679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 22.9811399792 11118676 11896295 11222880
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 22.9820603192
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.1720887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 17199135
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.1019131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.1017292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.1016740699
MESH:D011471 Prostatic Neoplasms resveratrol 2.1017804756 17675339 17636462 17718901 16731767 15767336
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.1016039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1015067354
MESH:D011471 Prostatic Neoplasms Vitamin E 2.1015084515
MESH:D011537 Pruritus Ethinyl Estradiol 3.2816919318 15861022
MESH:D019310 Pseudolymphoma Valproic Acid 4.5111422049 12752131
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D011629 Puberty, Precocious bisphenol A 4.7510548101
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.5516325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.5019058328
MESH:D015427 Reperfusion Injury resveratrol 6.5015827377 16317513 16314181 17520802 17058453
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8018990726
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.1319155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.9216646077
MESH:D012559 Schizophrenia Valproic Acid 2.0619110320 15737665
MESH:D012640 Seizures Valproic Acid 2.7116876388 17978042 14763951 15475178 1511512 11738929 11044598 3137016
MESH:D012871 Skin Diseases Vitamin E 2.4318709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 13.4010029692 19755658
MESH:D012878 Skin Neoplasms resveratrol 13.408985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 13.4019524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 13.4016192470
MESH:D013088 Spermatocele Ethinyl Estradiol 11.4716709447
MESH:D013088 Spermatocele Tamoxifen 11.4716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0019457130
MESH:D016135 Spinal Dysraphism sodium arsenite 9.4312854658
MESH:D016135 Spinal Dysraphism Valproic Acid 9.4319490988
MESH:D013226 Status Epilepticus Valproic Acid 4.5112833885
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.4017007042
MESH:D013274 Stomach Neoplasms Benzene 3.4012562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.4020155912 2093021
MESH:D020521 Stroke Vitamin E 3.4816517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.4416321402
MESH:D019966 Substance-Related Disorders bisphenol A 3.9516684133 16045194
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1115669648
MESH:D013953 Thymus Neoplasms Benzene 4.9210850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8712697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.0519014326
MESH:D014062 Tongue Neoplasms resveratrol 4.1716227395
MESH:D016171 Torsades de Pointes arsenic trioxide 3.9315213294
MESH:D014178 Translocation, Genetic Valproic Acid 5.2017262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.493119515
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 11.7920435036 12845720 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.7917053015
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 11.7916452187 11723127 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 11.7917572228 8653321 16712894
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.608888407
MESH:D014581 Urticaria Acetaminophen 2.9410982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 9.4317473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 9.4311813266
MESH:D014591 Uterine Diseases bisphenol A 4.9814652134
MESH:D014594 Uterine Neoplasms Benzene 15.8812562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 15.8814692618
MESH:D014594 Uterine Neoplasms resveratrol 15.8817044934
MESH:D014605 Uveitis Cyclosporine 3.961336536
MESH:D014652 Vascular Diseases sodium arsenite 4.3917056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5014671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.2617488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2215886252
MESH:D015430 Weight Gain Dietary Fats 3.7016723640
MESH:D014985 Xerophthalmia Cyclosporine 4.4117120751
No data
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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