AutismKB 2.0

Annotation Detail for CSDE1


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Basic Information Top
Gene Symbol:CSDE1 ( D1S155E,DKFZp779B0247,DKFZp779J1455,FLJ26882,RP5-1000E10.3,UNR )
Gene Full Name: cold shock domain containing E1, RNA-binding
Band: 1p13.2
Quick LinksEntrez ID:7812; OMIM: 191510; Uniprot ID:CSDE1_HUMAN; ENSEMBL ID: ENSG00000009307; HGNC ID: 29905
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200171Validated targets of C-MYC transcriptional repression
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C075773 4-phenylbutyric acid 4-phenylbutyric acid results in decreased expression of CSDE1 mRNAdecreases expression 14583596
D000082 Acetaminophen Acetaminophen affects the expression of CSDE1 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CSDE1 mRNAaffects expression 16483693
D005419 Flavonoids Flavonoids results in increased expression of CSDE1 mRNAincreases expression 18035473
C037219 quinoline quinoline analog results in increased expression of CSDE1 proteinincreases expression 18645022
C017947 sodium arsenite sodium arsenite results in increased expression of CSDE1 mRNAincreases expression 12016162
D014501 Uranium Uranium affects the expression of CSDE1 mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of CSDE1 mRNAaffects expression 15672453
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.9018287403
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.0815276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.2816712894 17306315
MESH:D000799 Angioedema Acetaminophen 4.2210982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.933084413
MESH:D006528 Carcinoma, Hepatocellular quinoline 4.93598648
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 4.9317306315 16507464 15276417
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.4318572023
MESH:D002386 Cataract Acetaminophen 2.7110977129
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 3.1420056578 19524636
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6414550746 12594235 12540782 15619225 12153990 2444490 10663392 17562736 14725611 10774834 11529661 11743745 19739265 19164858 16781746 12392966 12958197 16393943 14986274 19085960 16227642 19923254 10915739 19420014 11834606 16109766 11287661 16177239 19416960 16485898 11461765 11739529 18071297 18713872 12705907 15968718 16081117 19370779 17906064 11421492 17522070
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.4719426721
MESH:D005756 Gastritis Acetaminophen 4.0516983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 5.0216452187
MESH:D006390 Hemangioendothelioma quinoline 6.28598648
MESH:D006394 Hemangiosarcoma quinoline 5.24598648
MESH:D006689 Hodgkin Disease sodium arsenite 3.3612676792
MESH:D006930 Hyperalgesia Acetaminophen 2.8916870215
MESH:D007248 Infertility, Male sodium arsenite 3.1412646999 15346721
MESH:D007249 Inflammation Flavonoids 2.7517296493
MESH:D007674 Kidney Diseases Acetaminophen 6.3915629191 12587719
MESH:D007674 Kidney Diseases sodium arsenite 6.3920008137
MESH:D008107 Liver Diseases Acetaminophen 1.6716611625 19014921 16610002 12969438 11587558 19784758 12587719 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.4616871587 17185352
MESH:D008113 Liver Neoplasms sodium arsenite 2.4416712894 15276417
MESH:D008171 Lung Diseases sodium arsenite 3.3219095001
MESH:D008175 Lung Neoplasms sodium arsenite 1.8917306315 17077188 16712894 19931552 15276417
MESH:D008545 Melanoma sodium arsenite 2.0619082730 16487513
MESH:D008546 Melanoma, Experimental Acetaminophen 3.8719513568
MESH:D009362 Neoplasm Metastasis quinoline 4.12598648
MESH:D009369 Neoplasms 4-phenylbutyric acid 5.9519116145
MESH:D009369 Neoplasms sodium arsenite 5.9511559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.9720056578
MESH:D009436 Neural Tube Defects sodium arsenite 3.2912854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.0718514411
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.4917306315 15276417
MESH:D010146 Pain Acetaminophen 2.5916870215
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.2616039940
MESH:D012878 Skin Neoplasms sodium arsenite 2.7919524636 18572023
MESH:D016135 Spinal Dysraphism sodium arsenite 3.9812854658
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 2.5817306315 16712894 16452187 11723127
MESH:D014581 Urticaria Acetaminophen 3.2410982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.9911813266
MESH:D014652 Vascular Diseases sodium arsenite 4.7617056641
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018