Annotation Detail for CRELD1
Basic Information
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| Desease Name |
|---|
| Atrioventricular septal defect, partial, with heterotaxy syndrome |
| Atrioventricular septal defect, susceptibility to, 2 |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of CRELD1 mRNA | affects expression | 21346803
|
| C035207 |
4-amino-2,6-dinitrotoluene |
4-amino-2,6-dinitrotoluene affects the expression of CRELD1 mRNA | affects expression | 21346803
|
| D004041 |
Dietary Fats |
Dietary Fats results in decreased expression of CRELD1 mRNA | decreases expression | 18042831
|
| C041786 |
palm oil |
palm oil results in decreased expression of CRELD1 mRNA | decreases expression | 18042831
|
| D012643 |
Selenium |
Selenium results in increased expression of CRELD1 mRNA | increases expression | 19244175
|
| D014303 |
Trinitrotoluene |
Trinitrotoluene affects the expression of CRELD1 mRNA | affects expression | 21346803
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
4-amino-2,6-dinitrotoluene |
10.56 | 7525203 |
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Trinitrotoluene |
10.56 | 7525203 |
| MESH:D001161 |
Arteriosclerosis |
|
Dietary Fats |
4.31 | 15238619 |
| OMIM:606217 |
ATRIOVENTRICULAR SEPTAL DEFECT, SUSCEPTIBILITY TO, 2;AVSD2 ATRIOVENTRICULAR SEPTAL DEFECT, PARTIAL, WITH HETEROTAXY SYNDROME, |
marker/mechanism |
|
| |
| MESH:D001943 |
Breast Neoplasms |
|
Dietary Fats |
2.25 | 20435547 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
1.78 | 16705839 |
| MESH:D002386 |
Cataract |
|
4-amino-2,6-dinitrotoluene |
8.45 | 14694615 |
| MESH:D002386 |
Cataract |
|
Trinitrotoluene |
8.45 | 14694615 15817613 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.20 | 17936198 |
| MESH:D000013 |
Congenital Abnormalities |
|
4-amino-2,6-dinitrotoluene |
10.65 | 15095906 |
| MESH:D000013 |
Congenital Abnormalities |
|
Trinitrotoluene |
10.65 | 15095906 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
12.66 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
Trinitrotoluene |
12.66 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
9.72 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
4-amino-2,6-dinitrotoluene |
9.72 | 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
9.72 | 15131321 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Trinitrotoluene |
9.72 | 21346803 18551238 |
| MESH:D050171 |
Dyslipidemias |
|
Dietary Fats |
3.67 | 18367378 |
| MESH:D005234 |
Fatty Liver |
|
Dietary Fats |
3.56 | 17967931 18296743 19551842 19004024 |
| MESH:D005355 |
Fibrosis |
|
Dietary Fats |
3.94 | 18296743 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
3.25 | 17162251 |
| MESH:D006529 |
Hepatomegaly |
|
Trinitrotoluene |
4.65 | 15817613 |
| MESH:D006937 |
Hypercholesterolemia |
|
Dietary Fats |
3.92 | 21332399 |
| MESH:D006949 |
Hyperlipidemias |
|
Dietary Fats |
3.97 | 21332399 |
| MESH:D007248 |
Infertility, Male |
|
Trinitrotoluene |
3.87 | 12150543 |
| MESH:D007249 |
Inflammation |
|
Dietary Fats |
2.57 | 20412841 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
4.72 | 16624496 |
| MESH:D007333 |
Insulin Resistance |
|
Dietary Fats |
3.30 | 11836018 18457598 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.21 | 16518626 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
3.24 | 16705839 |
| MESH:D008103 |
Liver Cirrhosis |
|
Dietary Fats |
3.03 | 18296743 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
2.95 | 15318939 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
2.89 | 15107826 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
12.27 | 18551238 |
| MESH:D009336 |
Necrosis |
|
Trinitrotoluene |
12.27 | 18551238 |
| MESH:D009765 |
Obesity |
|
Dietary Fats |
2.34 | 16723640 21332399 17217161 11836018 19632207 20132043 20518802 18457598 18674790 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
17.12 | 16049721 12819281 |
| MESH:D009784 |
Occupational Diseases |
|
4-amino-2,6-dinitrotoluene |
17.12 | 14694615 |
| MESH:D009784 |
Occupational Diseases |
|
Trinitrotoluene |
17.12 | 12819281 14694615 17852074 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.41 | 15087411 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.89 | 18551238 |
| MESH:D012640 |
Seizures |
|
Trinitrotoluene |
6.89 | 18551238 |
| MESH:D013163 |
Splenomegaly |
|
Trinitrotoluene |
5.62 | 15817613 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
2.38 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
4.78 | 10091137 |
| MESH:D015430 |
Weight Gain |
|
Dietary Fats |
4.02 | 16723640 |
Related Pathway Information