AutismKB 2.0

Annotation Detail for COLEC11


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Basic Information Top
Gene Symbol:COLEC11 ( CL-K1-I,CL-K1-II,CL-K1-IIa,CL-K1-IIb,CLK1,DKFZp686N1868,MGC3279 )
Gene Full Name: collectin sub-family member 11
Band: 2p25.3
Quick LinksEntrez ID:78989; OMIM: 612502; Uniprot ID:COL11_HUMAN; ENSEMBL ID: ENSG00000118004; HGNC ID: 17213
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of COLEC11 mRNAaffects expression 17562736
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of COLEC11 mRNAdecreases expression 20106945
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of COLEC11 mRNAdecreases expression 17484886
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of COLEC11 mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of COLEC11 mRNAdecreases expression 19482888
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 4.076195326
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.866695378
MESH:D018248 Adenoma, Liver Cell Phenobarbital 4.6017620307
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.6419183758
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9920146248 17474063
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.3416011737 15721981 3786805 16192424 10355542 16050911 16097048 15700767 16124888 15673190 18705752 16227642
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.813084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 4.8118788625
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 4.811701930 20007298 6705139 17173139 20935162
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:C535586 Carnevale syndrome marker/mechanism 21258343
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.814080065
MESH:D019465 Craniofacial Abnormalities marker/mechanism 21258343
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0516781746 14550746 10915739 17562736 18713872 10663392 17906064 19370779 11743745 19164858 16109766 16393943 12705907 11529661 11287661 12594235 14725611 12392966 11739529 2444490 18071297 19923254 16177239 12540782 11461765 12153990 15968718 16485898 19085960 14986274 19416960 19420014 19739265 15619225 16081117 17522070 16227642 11421492 12958197 11834606 10774834
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 4.059327722 10092053 16227642 10915739 17522070 21278145 2869522 15027814 19085960 7120509 16177239 3732212 15968718 19336974 7440962 11566570 4309450 6884620 7179309 15998439 3786805 6623471
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D004421 Dystonia Phenobarbital 4.471851702
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.673659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.593922381 11558140
MESH:D004827 Epilepsy Phenobarbital 3.0620417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.916401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.817750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.653659116
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0816530937
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.5916045604 12631006 17595544 16239168 12795759 15959796 19224547 61145
MESH:D005355 Fibrosis Carbon Tetrachloride 4.0118705752
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8320471113
MESH:D006505 Hepatitis Carbon Tetrachloride 4.1019900420 19110552
MESH:D006529 Hepatomegaly Phenobarbital 4.0416109766
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.1616899240
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.6515338365
MESH:D007674 Kidney Diseases Acetaminophen 2.4012587719 15629191
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 7.2816943688 21278145 17157831 11903743 17174718 16239168 17334410 16221502 11408273
MESH:D008103 Liver Cirrhosis Phenobarbital 7.2821047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7518429990 16638106 16027843 17869086 18156304 18054572 18395914 15959796 15362042 16136751 15893842 15931870 15123356 18263696 18481824 17922224 14724832 17976157 12546737 17481882 18166357 15052691 17721639 16011737 17944888 17900296 17805973 18472094 18279442 17698563 15996030 16097048 11481614 16033810 15673190 18395095 12958196 18420326 18412020 12609069 18317297 12649538 16192424 12445418 15650968 14716833 15730626 12389079 15057751 17761835 16116963 18006644 12667390 15818738 18705752 14620537 12741479 15925388 16248980 12898905 17525996 12632514 18210741 17708605 13678700 14716496 18339082 17557913 12632512 16015684 12445421 17823541 10355542 12666154 15338365 15370692 15876570 14512876 17565644 18376398 18187930 18251166 12586293 18472332 18205269 18277467 18418968 17714472 17640975 14748882 17766677 17631135 20821823
MESH:D008107 Liver Diseases Acetaminophen 6.9616611625 19784758 12969438 19460945 11587558 19014921 16610002 12587719
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.9616964402 16246199 15830285 17285989 15720792
MESH:D008107 Liver Diseases Phenobarbital 6.9619363144
MESH:D017093 Liver Failure Carbon Tetrachloride 4.7315123358
MESH:D017114 Liver Failure, Acute Acetaminophen 10.7516871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 10.7514706259 16899240
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 8.1721137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 8.1719294768
MESH:D008113 Liver Neoplasms Phenobarbital 8.178742319 21047994 19073162 19812893 15975961 19482888
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 6.7412014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 6.741399818 6150874 17172636 2563599 18308698
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5720464547 20064080 18816296 18520028 18569708 20135361 6695378 20869020 17053015
MESH:C535704 Malpuech facial clefting syndrome marker/mechanism 21258343
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5016381670
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 5.1117484760
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3311141357
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:C537738 Oculopalatoskeletal syndrome marker/mechanism 21258343
MESH:D010018 Osteomalacia Phenobarbital 5.0017016548
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.6016965848
MESH:D010859 Pigmentation Disorders marker/mechanism 21258343
MESH:D011230 Precancerous Conditions Phenobarbital 3.992563599
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9117292933
MESH:D019310 Pseudolymphoma Phenobarbital 5.2212752131
MESH:D012640 Seizures Phenobarbital 2.9511442880 16876388 3137016 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 5.456407741
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5219755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.361399818
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3017053015
MESH:D014581 Urticaria Acetaminophen 3.4410982225
Pathway ID Pathway Name
KEGG:04145 Phagosome
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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