AutismKB 2.0

Annotation Detail for DBNDD1


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Basic Information Top
Gene Symbol:DBNDD1 ( FLJ12582,MGC3101 )
Gene Full Name: dysbindin (dystrobrevin binding protein 1) domain containing 1
Band: 16q24.3
Quick LinksEntrez ID:79007; OMIM: NA; Uniprot ID:DBND1_HUMAN; ENSEMBL ID: ENSG00000003249; HGNC ID: 28455
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of DBNDD1 proteinaffects expression 20106945
D000638 Amiodarone Amiodarone results in increased expression of DBNDD1 mRNAincreases expression 19774075
D004958 Estradiol Estradiol results in increased expression of DBNDD1 mRNAincreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Estradiol 2.1811473722
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.2518057881 18218290 20041841
MESH:D001281 Atrial Fibrillation Amiodarone 4.2318651412 19698954
MESH:D001778 Blood Coagulation Disorders Amiodarone 4.3819483382
MESH:D001943 Breast Neoplasms Estradiol 2.1018497071 16675129 17289903 19861407 12948864 17261762 14630087 17018787
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.2116111702
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 3.1912619106 21507988 12907637
MESH:D006528 Carcinoma, Hepatocellular Estradiol 3.1916924424
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 3.0115710769 19225199
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.8318974383
MESH:D002471 Cell Transformation, Neoplastic Estradiol 3.0618566989
MESH:D003928 Diabetic Nephropathies Estradiol 3.8319279558
MESH:D056486 Drug-Induced Liver Injury Amiodarone 2.4815265979 18218290
MESH:D016889 Endometrial Neoplasms Estradiol 3.2511473722 18566989 19148513
MESH:D005234 Fatty Liver Amiodarone 4.0014986274
MESH:D006529 Hepatomegaly Amiodarone 4.4015265979
MESH:D006558 Herpes Genitalis Estradiol 5.9015709030
MESH:D019584 Hot Flashes Estradiol 4.6217088409
MESH:D006937 Hypercholesterolemia Amiodarone 4.369751232 8137927
MESH:D007037 Hypothyroidism Amiodarone 5.1717991464 18020914
MESH:D007333 Insulin Resistance Estradiol 3.2316393666 16627594
MESH:D007674 Kidney Diseases Estradiol 2.8015618244
MESH:D007680 Kidney Neoplasms Estradiol 3.3615610895
MESH:D008064 Lipidoses Amiodarone 3.8215342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 1.6914659978 14716833
MESH:D008113 Liver Neoplasms Aflatoxin B1 2.479163691 15890375 2125692 18177683
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 2.998603461
MESH:D008133 Long QT Syndrome Amiodarone 3.9217391786 15350150 11989578
MESH:D008171 Lung Diseases Amiodarone 3.6512587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.3418516814
MESH:D008175 Lung Neoplasms Aflatoxin B1 1.8814755239
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.8217203775 11807958 11408345 16891317
MESH:D020149 Manganese Poisoning Estradiol 5.3519453300
MESH:D009181 Mycoses Amiodarone 5.7712754197 17974566
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.6216810080
MESH:D009389 Neovascularization, Pathologic Estradiol 4.4717289903
MESH:D009421 Nervous System Malformations Estradiol 4.2311399458 16427766
MESH:D010051 Ovarian Neoplasms Estradiol 2.3219401270
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.3720887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.0216740699
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9812490602 11597910 12832656
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.8318724381
MESH:D013276 Stomach Ulcer Amiodarone 3.7918087811
MESH:D013610 Tachycardia Amiodarone 4.8711238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.7719225199
MESH:D013959 Thyroid Diseases Amiodarone 5.6219731979
MESH:D013971 Thyrotoxicosis Amiodarone 5.5118020914 19584973
MESH:D013978 Tibial Fractures Estradiol 5.5519048282
MESH:D016171 Torsades de Pointes Amiodarone 4.9317467628 11989578
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018