AutismKB 2.0

Annotation Detail for SECISBP2


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Basic Information Top
Gene Symbol:SECISBP2 ( DKFZp686C09169,SBP2 )
Gene Full Name: SECIS binding protein 2
Band: 9q22.2
Quick LinksEntrez ID:79048; OMIM: 607693; Uniprot ID:SEBP2_HUMAN; ENSEMBL ID: ENSG00000187742; HGNC ID: 30972
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
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Desease Name
Thyroid hormone metabolism, abnormal
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of SECISBP2 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SECISBP2 mRNAaffects expression 16483693
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.4418287403
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 1.7916705839
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.7818551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 2.0621346803 18551238
MESH:D006130 Growth Disorders marker/mechanism 19602558
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.4116705839
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.7418551238
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.9312819281 16049721
MESH:D012640 Seizures 2,4-dinitrotoluene 2.8518551238
OMIM:609698 THYROID HORMONE METABOLISM, ABNORMAL marker/mechanism 19602558
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.4316049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 5.2010091137
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018