AutismKB 2.0

Annotation Detail for FASTKD3


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Basic Information Top
Gene Symbol:FASTKD3 ( FLJ23274,MGC142123,MGC5297 )
Gene Full Name: FAST kinase domains 3
Band: 5p15.31
Quick LinksEntrez ID:79072; OMIM: NA; Uniprot ID:FAKD3_HUMAN; ENSEMBL ID: ENSG00000124279; HGNC ID: 28758
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of FASTKD3 mRNAaffects expression 17562736
D016572 Cyclosporine Cyclosporine results in decreased expression of FASTKD3 mRNAdecreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of FASTKD3 mRNAaffects expression 17555576
D014810 Vitamin E Vitamin E results in decreased expression of FASTKD3 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.4916050911
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7912371664
MESH:D002779 Cholestasis Cyclosporine 8.7619486331
MESH:D002779 Cholestasis Ethinyl Estradiol 8.7616919318 17110522 17681005 17333356 16105132 11677210 15861022
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9319769572
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6719739265 15619225 16081117 19923254 16177239 14550746 14986274 18713872 10915739 11739529 19085960 17906064 18071297 19164858 11461765 2444490 19416960 12594235 11287661 11743745 11834606 12540782 16227642 19420014 14725611 10774834 16109766 12153990 16781746 11529661 12958197 10663392 12705907 19370779 12392966 11421492 16485898 15968718 17562736 16393943 17522070
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:C538011 Eales disease Vitamin E 5.439068938
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.6912538720
MESH:D005234 Fatty Liver Cyclosporine 9.0219224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 9.0215345470
MESH:D005355 Fibrosis Cyclosporine 3.7012639820 12168785
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.858708960
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1716080930
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.0515720958
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8116490937 16863852
MESH:D019584 Hot Flashes Vitamin E 4.6914716179
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D006973 Hypertension Cyclosporine 2.2110903974
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7317937319
MESH:D007251 Influenza, Human Vitamin E 4.9416624496
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.1615604871
MESH:D007674 Kidney Diseases Acetaminophen 11.2115629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 11.2118776723 10903974 8314463
MESH:D007674 Kidney Diseases Vitamin E 11.2112488133
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0812371664
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9116169303
MESH:D008107 Liver Diseases Acetaminophen 1.7019014921 16611625 19460945 16610002 12969438 12587719 11587558 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6317185352 16871587
MESH:D008171 Lung Diseases Vitamin E 3.4316863852
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.5116801185
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6519348381 18481113
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D011230 Precancerous Conditions Cyclosporine 3.5912371664
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2415084515
MESH:D011537 Pruritus Ethinyl Estradiol 3.9416919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.3316882103
MESH:D012871 Skin Diseases Vitamin E 2.5218709164
MESH:D013088 Spermatocele Ethinyl Estradiol 4.6616709447
MESH:D020521 Stroke Vitamin E 3.8416517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D014581 Urticaria Acetaminophen 3.4410982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D014605 Uveitis Cyclosporine 4.711336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9715869587 14671159
MESH:D014985 Xerophthalmia Cyclosporine 5.1617120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA145148868
    • No data
    Releated disease ID Related disease Name
    PA445095Neural Tube Defects
    PA446286Spina Bifida Cystica
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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