AutismKB 2.0

Annotation Detail for PPDPF


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Basic Information Top
Gene Symbol:PPDPF ( C20orf149,FLJ21046,MGC2479,dJ697K14.9 )
Gene Full Name: pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)
Band: 20q13.33
Quick LinksEntrez ID:79144; OMIM: NA; Uniprot ID:PPDPF_HUMAN; ENSEMBL ID: ENSG00000125534; HGNC ID: 16142
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000638 Amiodarone Amiodarone affects the expression of PPDPF mRNAaffects expression 19483382
D001553 Benzbromarone Benzbromarone affects the expression of PPDPF mRNAaffects expression 19483382
D002994 Clofibrate Clofibrate affects the expression of PPDPF mRNAaffects expression 19483382
D005001 Ethionine Ethionine affects the expression of PPDPF mRNAaffects expression 19483382
D009853 Omeprazole Omeprazole affects the expression of PPDPF mRNAaffects expression 19483382
C006253 pirinixic acid pirinixic acid affects the expression of PPDPF mRNAaffects expression 19483382
D011441 Propylthiouracil Propylthiouracil affects the expression of PPDPF mRNAaffects expression 19483382
D013853 Thioacetamide Thioacetamide affects the expression of PPDPF mRNAaffects expression 19483382
D014810 Vitamin E Vitamin E results in decreased expression of PPDPF mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.3418653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.7616434500
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.9918057881 18218290 20041841
MESH:D001281 Atrial Fibrillation Amiodarone 4.0519698954 18651412
MESH:D001778 Blood Coagulation Disorders Amiodarone 55.1819483382
MESH:D001778 Blood Coagulation Disorders Benzbromarone 55.1819483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 55.1819483382
MESH:D001778 Blood Coagulation Disorders Ethionine 55.1819483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 55.1819483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 55.1819483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 55.1819483382
MESH:D001778 Blood Coagulation Disorders Thioacetamide 55.1819483382
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.1916050911
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 3.631701930
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 3.6317997003
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.9519225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.3718974383
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 3.661399818
MESH:D002637 Chest Pain Omeprazole 5.4215447763
MESH:D018281 Cholangiocarcinoma Thioacetamide 4.4718291259
MESH:D002779 Cholestasis pirinixic acid 2.9719176532
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5118249437
MESH:D056486 Drug-Induced Liver Injury Amiodarone 4.4418218290 15265979
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 4.4412963478
MESH:D004381 Duodenal Ulcer Omeprazole 4.5715991576 21218061 16613094 17151854
MESH:D050171 Dyslipidemias Clofibrate 4.2116707586
MESH:C538011 Eales disease Vitamin E 5.029068938
MESH:D004487 Edema pirinixic acid 2.6812083418
MESH:D005218 Fat Necrosis Thioacetamide 6.0416456712
MESH:D005234 Fatty Liver Amiodarone 14.4614986274
MESH:D005234 Fatty Liver Clofibrate 14.4619224547
MESH:D005234 Fatty Liver pirinixic acid 14.4620131406 19236843
MESH:D006330 Heart Defects, Congenital Vitamin E 3.0816080930
MESH:D006333 Heart Failure pirinixic acid 2.6520558911
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.7817276928 18665440 15929193
MESH:D006505 Hepatitis Thioacetamide 4.4516456712
MESH:D006529 Hepatomegaly Amiodarone 9.4515265979
MESH:D006529 Hepatomegaly pirinixic acid 9.4519772884 16221962 19176532 18467677
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7616490937 16863852
MESH:D019584 Hot Flashes Vitamin E 4.2914716179
MESH:D006937 Hypercholesterolemia Amiodarone 4.088137927 9751232
MESH:D006943 Hyperglycemia pirinixic acid 3.3820558911
MESH:D007037 Hypothyroidism Amiodarone 12.4918020914 17991464
MESH:D007037 Hypothyroidism Propylthiouracil 12.4918031379 8137927
MESH:D007251 Influenza, Human Vitamin E 4.5316624496
MESH:D007333 Insulin Resistance pirinixic acid 2.7616306350
MESH:D007674 Kidney Diseases Vitamin E 2.9112488133
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 4.2719248655
MESH:D008064 Lipidoses Amiodarone 3.6517567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.6715474484
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 3.6717050028 15288473 16343077 15334695 18295389 16489207 17355460 16511523 18395095 18263696 16126171 12679928 15095483 18606216 15288472 12531686 18380797 10677585 15474484 16097051 18032466 15716488 15075984 18458672 15316131 12891558 11682029 18031379 17292413 12085344 17629604 11481614 11172339 18416461 15078482 12557150 16098781 14739098 15362042 15158331 15465738 18615449 16248980 17127702 12175628
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 3.6716169303
MESH:D008107 Liver Diseases Thioacetamide 2.7415158337 18374380 16337175
MESH:D017114 Liver Failure, Acute Thioacetamide 4.5015633222 12479984 15313186 17276928
MESH:D008113 Liver Neoplasms pirinixic acid 1.8816377806 20007298 15890375
MESH:D008133 Long QT Syndrome Amiodarone 3.7315350150 11989578 17391786
MESH:D008171 Lung Diseases Amiodarone 7.9612587719
MESH:D008171 Lung Diseases Vitamin E 7.9616863852
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.8018516814
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D009135 Muscular Diseases pirinixic acid 3.7616239165
MESH:D009181 Mycoses Amiodarone 5.2217974566 12754197
MESH:D009203 Myocardial Infarction pirinixic acid 2.2119151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1016411023
MESH:D009369 Neoplasms pirinixic acid 2.0317405874
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 5.209802331
MESH:D009765 Obesity pirinixic acid 1.8520558911
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2715084515
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9212832656 12490602 11597910
MESH:D015427 Reperfusion Injury pirinixic acid 2.4719058328
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.3718724381
MESH:D012871 Skin Diseases Vitamin E 2.4818709164
MESH:D013272 Stomach Diseases Omeprazole 4.8918545984
MESH:D013276 Stomach Ulcer Amiodarone 8.2718087811
MESH:D013276 Stomach Ulcer Omeprazole 8.2711906479 18237397 17977527 10750652 15991576 16755016
MESH:D020521 Stroke Vitamin E 3.6816517955
MESH:D013610 Tachycardia Amiodarone 4.5311238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.4319225199
MESH:D013959 Thyroid Diseases Amiodarone 5.0819731979
MESH:D013964 Thyroid Neoplasms Propylthiouracil 3.8315710170
MESH:D013971 Thyrotoxicosis Amiodarone 5.1218020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.4711989578 17467628
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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