Annotation Detail for GDPD3
Basic Information Top
Gene Symbol: | GDPD3 ( FLJ22603,MGC4171 ) |
---|---|
Gene Full Name: | glycerophosphodiester phosphodiesterase domain containing 3 |
Band: | 16p11.2 |
Quick Links | Entrez ID:79153; OMIM: NA; Uniprot ID:GDPD3_HUMAN; ENSEMBL ID: ENSG00000102886; HGNC ID: 28638 |
Relate to Another Database: | SFARIGene; denovo-db |
Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
---|---|---|---|---|
D000638 | Amiodarone | Amiodarone results in increased expression of GDPD3 mRNA | increases expression | 17567588 |
D000639 | Amitriptyline | Amitriptyline results in increased expression of GDPD3 mRNA | increases expression | 17567588 15342952 |
C084597 | chlorcyclizine | chlorcyclizine results in increased expression of GDPD3 mRNA | increases expression | 15342952 |
D002746 | Chlorpromazine | Chlorpromazine results in increased expression of GDPD3 mRNA | increases expression | 15342952 |
D015283 | Citalopram | Citalopram results in increased expression of GDPD3 mRNA | increases expression | 17567588 |
D003024 | Clozapine | Clozapine results in increased expression of GDPD3 mRNA | increases expression | 15342952 |
D004316 | Doxepin | Doxepin results in increased expression of GDPD3 mRNA | increases expression | 17567588 |
D005424 | Flecainide | Flecainide results in increased expression of GDPD3 mRNA | increases expression | 15342952 |
D005473 | Fluoxetine | Fluoxetine results in increased expression of GDPD3 mRNA | increases expression | 17567588 |
D005492 | Folic Acid | Folic Acid affects the expression of GDPD3 mRNA | affects expression | 17320366 |
D007099 | Imipramine | Imipramine results in increased expression of GDPD3 mRNA | increases expression | 15342952 17567588 |
D007654 | Ketoconazole | Ketoconazole results in increased expression of GDPD3 mRNA | increases expression | 15342952 |
D017336 | Loratadine | Loratadine results in increased expression of GDPD3 mRNA | increases expression | 15342952 |
D010480 | Perhexiline | Perhexiline results in increased expression of GDPD3 mRNA | increases expression | 15342952 |
D020280 | Sertraline | Sertraline results in increased expression of GDPD3 mRNA | increases expression | 17567588 15342952 |
D013629 | Tamoxifen | Tamoxifen results in increased expression of GDPD3 mRNA | increases expression | 17567588 15342952 |
D001371 | trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride results in increased expression of GDPD3 mRNA | increases expression | 15342952 |
D014302 | Trinitrobenzenesulfonic Acid | Trinitrobenzenesulfonic Acid results in decreased expression of GDPD3 mRNA | decreases expression | 17982090 |
Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
---|---|---|---|---|---|
MESH:D000008 | Abdominal Neoplasms | Tamoxifen | 4.52 | 14745880 | |
MESH:D058186 | Acute Kidney Injury | Folic Acid | 4.29 | 17003819 16316344 16595132 | |
MESH:D000236 | Adenoma | Folic Acid | 3.77 | 16963246 | |
MESH:D000380 | Agranulocytosis | Clozapine | 5.02 | 12649775 14617031 16160616 | |
OMIM:607154 | ALLERGIC RHINITIS | Loratadine | 5.72 | 16527031 | |
MESH:D000544 | Alzheimer Disease | Folic Acid | 3.04 | 17116317 | |
MESH:D001008 | Anxiety Disorders | Citalopram | 15.22 | 18083778 | |
MESH:D001008 | Anxiety Disorders | Fluoxetine | 15.22 | 18083778 | |
MESH:D001008 | Anxiety Disorders | Sertraline | 15.22 | 18822694 | |
MESH:D001145 | Arrhythmias, Cardiac | Amiodarone | 3.76 | 18218290 20041841 18057881 | |
MESH:D001249 | Asthma | Loratadine | 4.21 | 9196086 | |
MESH:D001281 | Atrial Fibrillation | Amiodarone | 3.87 | 18651412 19698954 | |
MESH:D001321 | Autistic Disorder | Citalopram | 2.96 | 19232924 18775368 | |
MESH:D001321 | Autistic Disorder | Fluoxetine | 2.96 | 18775368 19232924 | |
MESH:D001321 | Autistic Disorder | Folic Acid | 2.96 | 21388746 | |
MESH:D001321 | Autistic Disorder | Sertraline | 2.96 | 18775368 | |
MESH:D001778 | Blood Coagulation Disorders | Amiodarone | 3.86 | 19483382 | |
MESH:D001943 | Breast Neoplasms | Folic Acid | 2.51 | 16777985 | |
MESH:D001943 | Breast Neoplasms | Tamoxifen | 2.51 | 19189212 18351453 20390343 19084267 19189210 17893378 21138602 19221464 17261762 19011961 19288272 20135344 19410462 20544844 17440819 15668708 19059307 19115204 19487384 11161223 16818667 18425577 19244106 16202921 18984771 18855134 19066611 15565566 17049068 19142967 20065188 18629630 18821012 19155303 20005174 18815881 19200415 16873071 16273361 19103187 21152245 18997820 19289846 20859285 17242785 | |
MESH:D018270 | Carcinoma, Ductal, Breast | Tamoxifen | 4.47 | 19066611 | |
MESH:D006528 | Carcinoma, Hepatocellular | Tamoxifen | 1.82 | 16924424 | |
MESH:D002295 | Carcinoma, Transitional Cell | Tamoxifen | 3.57 | 17572228 | |
MESH:D002311 | Cardiomyopathy, Dilated | Amiodarone | 2.88 | 19225199 15710769 | |
MESH:D002318 | Cardiovascular Diseases | Folic Acid | 3.92 | 16755160 | |
MESH:D002341 | Carotid Artery Thrombosis | Amiodarone | 5.05 | 18974383 | |
MESH:D002659 | Child Development Disorders, Pervasive | Citalopram | 4.54 | 15782081 | |
MESH:D002971 | Cleft Lip | Folic Acid | 3.96 | 21254359 | |
MESH:D002972 | Cleft Palate | Folic Acid | 3.55 | 8946559 21254359 | |
MESH:D003072 | Cognition Disorders | Clozapine | 4.92 | 17123785 | |
MESH:D003092 | Colitis | Trinitrobenzenesulfonic Acid | 4.51 | 16804969 17991707 16782535 17936198 18200517 16867261 16474422 18023891 11698051 | |
MESH:D003093 | Colitis, Ulcerative | Trinitrobenzenesulfonic Acid | 3.43 | 17276891 | |
MESH:D015179 | Colorectal Neoplasms | Folic Acid | 2.70 | 17245555 16963246 17087956 16985020 17116713 | |
MESH:D003711 | Demyelinating Diseases | Tamoxifen | 4.32 | 19031437 | |
MESH:D003866 | Depressive Disorder | Amitriptyline | 29.61 | 18083778 15014590 | |
MESH:D003866 | Depressive Disorder | Citalopram | 29.61 | 15014590 | |
MESH:D003866 | Depressive Disorder | Doxepin | 29.61 | 15014590 | |
MESH:D003866 | Depressive Disorder | Fluoxetine | 29.61 | 15014590 | |
MESH:D003866 | Depressive Disorder | Imipramine | 29.61 | 20305041 | |
MESH:D003866 | Depressive Disorder | Sertraline | 29.61 | 20305041 15014590 18822694 | |
MESH:D003865 | Depressive Disorder, Major | Sertraline | 5.32 | 16968574 | |
MESH:D003924 | Diabetes Mellitus, Type 2 | Clozapine | 5.01 | 16402076 | |
MESH:D003924 | Diabetes Mellitus, Type 2 | Folic Acid | 5.01 | 16886840 | |
MESH:D003928 | Diabetic Nephropathies | Tamoxifen | 3.44 | 19279558 | |
MESH:D006970 | Disorders of Excessive Somnolence | Clozapine | 5.53 | 15331141 | |
MESH:D056486 | Drug-Induced Liver Injury | Amiodarone | 6.63 | 15265979 18218290 | |
MESH:D056486 | Drug-Induced Liver Injury | Chlorpromazine | 6.63 | 11461765 | |
MESH:D056486 | Drug-Induced Liver Injury | Ketoconazole | 6.63 | 18289764 | |
MESH:D050171 | Dyslipidemias | Clozapine | 4.15 | 16402076 | |
MESH:D004487 | Edema | Amitriptyline | 11.92 | 12798668 | |
MESH:D004487 | Edema | Fluoxetine | 11.92 | 12798668 | |
MESH:D004487 | Edema | Imipramine | 11.92 | 12798668 | |
MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Tamoxifen | 3.50 | 19031437 | |
MESH:D016889 | Endometrial Neoplasms | Folic Acid | 7.67 | 17301261 | |
MESH:D016889 | Endometrial Neoplasms | Tamoxifen | 7.67 | 20544844 19155303 16202921 17893378 | |
MESH:D017889 | Exfoliation Syndrome | Folic Acid | 5.46 | 16504073 | |
MESH:D005234 | Fatty Liver | Amiodarone | 7.82 | 14986274 | |
MESH:D005234 | Fatty Liver | Tamoxifen | 7.82 | 14986274 19224547 | |
MESH:D052776 | Female Urogenital Diseases | Tamoxifen | 3.21 | 16709447 | |
MESH:D018221 | Fibromatosis, Abdominal | Tamoxifen | 4.49 | 14745880 | |
MESH:D018222 | Fibromatosis, Aggressive | Tamoxifen | 4.15 | 19069698 | |
MESH:D005355 | Fibrosis | Trinitrobenzenesulfonic Acid | 4.31 | 17994277 | |
MESH:D005756 | Gastritis | Folic Acid | 5.06 | 17171786 | |
MESH:D005901 | Glaucoma | Folic Acid | 5.04 | 16504073 | |
MESH:D006330 | Heart Defects, Congenital | Folic Acid | 3.77 | 16524890 17286298 | |
MESH:D006529 | Hepatomegaly | Amiodarone | 3.71 | 15265979 | |
MESH:D006561 | Herpes Simplex | Chlorpromazine | 5.25 | 1682908 | |
MESH:D006679 | HIV Seropositivity | Folic Acid | 5.46 | 17209195 | |
MESH:D019584 | Hot Flashes | Fluoxetine | 5.28 | 14716179 | |
MESH:D006816 | Huntington Disease | Sertraline | 5.98 | 18403212 | |
MESH:D006937 | Hypercholesterolemia | Amiodarone | 3.83 | 9751232 8137927 | |
MESH:D020138 | Hyperhomocysteinemia | Folic Acid | 4.46 | 16755160 16395265 16397167 16865747 16433478 | |
MESH:D006948 | Hyperkinesis | Clozapine | 4.87 | 16046005 | |
MESH:D007021 | Hypospadias | Loratadine | 6.07 | 16407038 | |
MESH:D007037 | Hypothyroidism | Amiodarone | 4.47 | 18020914 17991464 | |
MESH:D007249 | Inflammation | Amitriptyline | 12.02 | 12798668 | |
MESH:D007249 | Inflammation | Fluoxetine | 12.02 | 12798668 | |
MESH:D007249 | Inflammation | Imipramine | 12.02 | 12798668 | |
MESH:D007249 | Inflammation | Tamoxifen | 12.02 | 19457130 | |
MESH:D015212 | Inflammatory Bowel Diseases | Trinitrobenzenesulfonic Acid | 3.56 | 18200517 | |
MESH:D007410 | Intestinal Diseases | Trinitrobenzenesulfonic Acid | 4.57 | 17994277 | |
MESH:D007680 | Kidney Neoplasms | Tamoxifen | 3.01 | 18625569 | |
MESH:D016773 | Leishmaniasis, Cutaneous | Ketoconazole | 4.66 | 2166429 19744259 1311351 8889330 | |
MESH:D007898 | Leishmaniasis, Visceral | Ketoconazole | 4.51 | 11332679 | |
MESH:D008064 | Lipidoses | marker/mechanism | 15342952 16919414 | ||
MESH:D008064 | Lipidoses | Amiodarone | 85.07 | 15342952 17567588 | |
MESH:D008064 | Lipidoses | Amitriptyline | 85.07 | 17567588 15342952 | |
MESH:D008064 | Lipidoses | chlorcyclizine | 85.07 | 15342952 | |
MESH:D008064 | Lipidoses | Chlorpromazine | 85.07 | 15342952 17567588 | |
MESH:D008064 | Lipidoses | Citalopram | 85.07 | 17567588 | |
MESH:D008064 | Lipidoses | Clozapine | 85.07 | 17567588 | |
MESH:D008064 | Lipidoses | Fluoxetine | 85.07 | 17567588 15342952 | |
MESH:D008064 | Lipidoses | Imipramine | 85.07 | 17567588 15342952 | |
MESH:D008064 | Lipidoses | Ketoconazole | 85.07 | 17567588 | |
MESH:D008064 | Lipidoses | Loratadine | 85.07 | 17567588 | |
MESH:D008064 | Lipidoses | Perhexiline | 85.07 | 15342952 17567588 | |
MESH:D008064 | Lipidoses | Sertraline | 85.07 | 17567588 | |
MESH:D008064 | Lipidoses | Tamoxifen | 85.07 | 15342952 17567588 | |
MESH:D008064 | Lipidoses | trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 85.07 | 15342952 | |
MESH:D008106 | Liver Cirrhosis, Experimental | Tamoxifen | 1.74 | 18564211 | |
MESH:D008107 | Liver Diseases | Chlorpromazine | 4.97 | 14986274 | |
MESH:D008107 | Liver Diseases | Folic Acid | 4.97 | 16877991 | |
MESH:D008113 | Liver Neoplasms | Tamoxifen | 2.20 | 16684651 | |
MESH:D008133 | Long QT Syndrome | Amiodarone | 3.54 | 17391786 15350150 11989578 | |
MESH:D008171 | Lung Diseases | Amiodarone | 3.34 | 12587719 | |
MESH:D017563 | Lung Diseases, Interstitial | Amiodarone | 4.45 | 18516814 | |
MESH:D008175 | Lung Neoplasms | Tamoxifen | 1.74 | 18625569 | |
MESH:D008180 | Lupus Erythematosus, Systemic | Folic Acid | 3.32 | 17718048 | |
MESH:D016778 | Malaria, Falciparum | Perhexiline | 5.93 | 16882315 | |
MESH:D015674 | Mammary Neoplasms, Animal | Tamoxifen | 3.72 | 19428831 | |
MESH:D008325 | Mammary Neoplasms, Experimental | Tamoxifen | 2.59 | 11731420 16827153 19196723 19196722 14580682 | |
MESH:D020149 | Manganese Poisoning | Tamoxifen | 4.52 | 19453300 | |
MESH:D019767 | Maxillofacial Abnormalities | Folic Acid | 5.66 | 16832597 | |
MESH:D008545 | Melanoma | Tamoxifen | 1.87 | 12393984 19393235 | |
MESH:D018328 | Melanoma, Amelanotic | Tamoxifen | 4.15 | 15990972 | |
MESH:D001523 | Mental Disorders | Amitriptyline | 42.73 | 16856516 | |
MESH:D001523 | Mental Disorders | Chlorpromazine | 42.73 | 16856516 | |
MESH:D001523 | Mental Disorders | Citalopram | 42.73 | 16856516 | |
MESH:D001523 | Mental Disorders | Clozapine | 42.73 | 16856516 | |
MESH:D001523 | Mental Disorders | Doxepin | 42.73 | 16856516 | |
MESH:D001523 | Mental Disorders | Fluoxetine | 42.73 | 16856516 | |
MESH:D001523 | Mental Disorders | Imipramine | 42.73 | 16856516 | |
MESH:D001523 | Mental Disorders | Sertraline | 42.73 | 16856516 | |
MESH:D024821 | Metabolic Syndrome X | Clozapine | 4.37 | 19142101 | |
MESH:D008881 | Migraine Disorders | Amitriptyline | 4.76 | 18803445 | |
MESH:D009175 | Mycoplasma Infections | Chlorpromazine | 5.97 | 10773494 | |
MESH:D009181 | Mycoses | Amiodarone | 4.87 | 12754197 17974566 | |
MESH:D009207 | Myoclonus | Fluoxetine | 5.84 | 8041377 | |
MESH:D009362 | Neoplasm Metastasis | Tamoxifen | 2.53 | 19393235 | |
MESH:D009364 | Neoplasm Recurrence, Local | Tamoxifen | 2.50 | 19410462 | |
MESH:D009376 | Neoplasms, Hormone-Dependent | Tamoxifen | 3.97 | 19196722 19200415 19189210 | |
MESH:D009436 | Neural Tube Defects | Folic Acid | 3.92 | 17438019 | |
MESH:D009503 | Neutropenia | Folic Acid | 4.46 | 16322990 | |
MESH:D009765 | Obesity | Clozapine | 3.01 | 19142110 18515891 | |
MESH:D009771 | Obsessive-Compulsive Disorder | Fluoxetine | 5.40 | 20418887 | |
MESH:D010146 | Pain | Amitriptyline | 11.69 | 12798668 | |
MESH:D010146 | Pain | Fluoxetine | 11.69 | 12798668 | |
MESH:D010146 | Pain | Imipramine | 11.69 | 12798668 | |
MESH:D010195 | Pancreatitis | Trinitrobenzenesulfonic Acid | 4.16 | 17698068 | |
MESH:D020774 | Pick Disease of the Brain | Fluoxetine | 5.96 | 8041377 | |
MESH:D011471 | Prostatic Neoplasms | Ketoconazole | 3.73 | 17404083 | |
MESH:D011471 | Prostatic Neoplasms | Tamoxifen | 3.73 | 15067354 | |
MESH:D011618 | Psychotic Disorders | Clozapine | 4.15 | 15331141 | |
MESH:D011658 | Pulmonary Fibrosis | Amiodarone | 2.84 | 11597910 12490602 12832656 | |
MESH:D051437 | Renal Insufficiency | Folic Acid | 4.74 | 15728788 | |
MESH:D012559 | Schizophrenia | Clozapine | 4.11 | 20521320 20107430 18806925 20452607 20168265 19369910 11151749 17726453 17667964 20580759 16141801 18855531 17123785 11763009 20521326 | |
MESH:D012559 | Schizophrenia | Folic Acid | 4.11 | 16641680 | |
MESH:D020230 | Serotonin Syndrome | Fluoxetine | 5.87 | 8704074 | |
OMIM:609620 | SHORT QT SYNDROME 1 | Amiodarone | 5.05 | 18724381 | |
MESH:D012871 | Skin Diseases | Folic Acid | 3.24 | 18709164 | |
MESH:D012892 | Sleep Deprivation | Imipramine | 6.16 | 19798453 | |
MESH:D007319 | Sleep Initiation and Maintenance Disorders | Amitriptyline | 10.99 | 15341891 | |
MESH:D007319 | Sleep Initiation and Maintenance Disorders | Doxepin | 10.99 | 15341891 | |
MESH:D013088 | Spermatocele | Tamoxifen | 4.26 | 16709447 | |
MESH:D013118 | Spinal Cord Diseases | Folic Acid | 5.46 | 16361298 | |
MESH:D013119 | Spinal Cord Injuries | Tamoxifen | 4.00 | 19457130 | |
MESH:D013274 | Stomach Neoplasms | Folic Acid | 2.70 | 17171786 | |
MESH:D013276 | Stomach Ulcer | Amiodarone | 3.28 | 18087811 | |
MESH:D020521 | Stroke | Folic Acid | 4.29 | 16517955 | |
MESH:D013610 | Tachycardia | Amiodarone | 4.25 | 11238279 | |
MESH:D017180 | Tachycardia, Ventricular | Amiodarone | 4.15 | 19225199 | |
MESH:D013959 | Thyroid Diseases | Amiodarone | 4.73 | 19731979 | |
MESH:D013971 | Thyrotoxicosis | Amiodarone | 4.82 | 18020914 19584973 | |
MESH:D016171 | Torsades de Pointes | Amiodarone | 10.91 | 11989578 17467628 | |
MESH:D016171 | Torsades de Pointes | Flecainide | 10.91 | 17467628 | |
MESH:D001749 | Urinary Bladder Neoplasms | Tamoxifen | 2.34 | 17572228 16712894 8653321 | |
MESH:D014581 | Urticaria | Loratadine | 5.33 | 2568013 | |
MESH:D015430 | Weight Gain | Clozapine | 4.43 | 20521320 17502770 16402076 20107430 20564506 16141801 | |
MESH:D015431 | Weight Loss | Clozapine | 5.04 | 17933447 |
No data |