AutismKB 2.0

Annotation Detail for IRX3


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Basic Information Top
Gene Symbol:IRX3 ( FLJ99187,IRX-1,IRXB1 )
Gene Full Name: iroquois homeobox 3
Band: 16q12.2
Quick LinksEntrez ID:79191; OMIM: 612985; Uniprot ID:IRX3_HUMAN; ENSEMBL ID: ENSG00000177508; HGNC ID: 14360
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016572 Cyclosporine Cyclosporine results in decreased expression of IRX3 mRNAdecreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of IRX3 mRNAdecreases expression 18042831
D002117 Calcitriol Calcitriol results in decreased expression of IRX3 mRNAdecreases expression 16002434
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of IRX3 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of IRX3 mRNAdecreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of IRX3 mRNAaffects cotreatment|decreases expression 17942748
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of IRX3 mRNAaffects cotreatment|increases expression 17183730
C041786 palm oil palm oil results in decreased expression of IRX3 mRNAdecreases expression 18042831
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of IRX3 mRNAaffects binding|decreases expression|increases activity 19710929
D014284 Triiodothyronine Triiodothyronine results in increased expression of IRX3 mRNAincreases expression 17403546
D013629 Tamoxifen Tamoxifen affects the expression of IRX3 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of IRX3 mRNAdecreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of IRX3 mRNAaffects cotreatment|decreases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of IRX3 mRNAincreases expression 17586704
D014212 Tretinoin Tretinoin results in decreased expression of IRX3 mRNAdecreases expression 17218384
D014212 Tretinoin Tretinoin results in increased expression of IRX3 mRNAincreases expression 16604517
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of IRX3 mRNAaffects cotreatment|increases expression 17183730
C025643 vinclozolin vinclozolin affects the expression of IRX3 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6814745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.7011752688 14514962 15322242
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 8.708875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.0119490988
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0817505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.2018653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8314692618
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.3016434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.3016835633
MESH:D000505 Alopecia Tretinoin 3.6815955085
MESH:D000550 Amblyopia Valproic Acid 5.3717688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0211748828
MESH:D001008 Anxiety Disorders Valproic Acid 9.0717497229
MESH:D001008 Anxiety Disorders vinclozolin 9.0719015723
MESH:D001161 Arteriosclerosis Dietary Fats 10.2615238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 10.2611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.3715885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.3716412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2816292516
MESH:D001249 Asthma Tretinoin 2.3616456186
MESH:D001321 Autistic Disorder Valproic Acid 2.0017157402 15238991 19232924 18558336 18940202 18985861 18775368 18316065 18396377 17507914 16609825 20603192 17688650 19460635 18177632
MESH:D001471 Barrett Esophagus Tretinoin 4.5016935849
MESH:D001714 Bipolar Disorder Valproic Acid 3.1117594078 20046352
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.7619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.7612125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 15.7616206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.9215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 8.1915746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 8.198888407
MESH:D001943 Breast Neoplasms Calcitriol 2.3511237771
MESH:D001943 Breast Neoplasms Dietary Fats 2.3520435547
MESH:D001943 Breast Neoplasms Tamoxifen 2.3520544844 18425577 19155303 17440819 16202921 20859285 15668708 19288272 16273361 16818667 18855134 19289846 19059307 21138602 18351453 17242785 19011961 19410462 19189210 18821012 19221464 18997820 17893378 16873071 15565566 17049068 19142967 19200415 19084267 18984771 18629630 20065188 19115204 20005174 20135344 17261762 11161223 21152245 19189212 19487384 18815881 19066611 19103187 20390343 19244106
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3520435547
MESH:D001943 Breast Neoplasms Tretinoin 2.3516873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.7116813970
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.6119066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2916168501
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 3.0616924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 3.061917145
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 4.8511237771
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.8516096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6917572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4118670907 16120746 18850075
MESH:D002386 Cataract Tretinoin 3.1417460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.5812371664
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.7116129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.7320734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2316835633
MESH:D002779 Cholestasis Cyclosporine 13.7019486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.7017681005 15861022 16919318 17110522 16105132 11677210 17333356
MESH:D002779 Cholestasis pirinixic acid 13.7019176532
MESH:D002822 Choriocarcinoma Tretinoin 5.2916461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.8715668235 15340226 12621046 8697196 16354765
MESH:D002972 Cleft Palate Tretinoin 5.879407595
MESH:D003092 Colitis Tretinoin 3.8117035595
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1317141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.8015322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.809664655 16925845 8800419 10589399 9211117 17551590 9224671 9125849 14991402 9142499
MESH:D019465 Craniofacial Abnormalities Valproic Acid 3.8017688650 16575769 8888407
MESH:D003456 Cryptorchidism vinclozolin 4.4414966744
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4719031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4618249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6817107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.5519279558
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.8420420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 3.841733752 19641884
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8211462148
MESH:D050171 Dyslipidemias Dietary Fats 3.5118367378
MESH:D004421 Dystonia Valproic Acid 4.141851702
MESH:D004487 Edema pirinixic acid 6.8112083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.8111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.4016714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 12.4018230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 15.9215138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.9212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.9219031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.6116202921 20544844 19155303 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 7.6116569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.1010568697 9294722
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.263659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.0516628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.9718234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.667562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.407750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.183659116
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 9.0411564622
MESH:D005124 Eye Abnormalities Tretinoin 9.049664655 16938888
MESH:D005234 Fatty Liver Cyclosporine 31.9019224547
MESH:D005234 Fatty Liver Dietary Fats 31.9017967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 31.9015345470
MESH:D005234 Fatty Liver pirinixic acid 31.9020131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 31.9014986274 19224547
MESH:D005234 Fatty Liver Valproic Acid 31.9014986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2816709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5611858732
MESH:D005315 Fetal Diseases Valproic Acid 5.0216575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.2318558336 8888407
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.6414745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.3019069698
MESH:D005355 Fibrosis Cyclosporine 22.0612639820 12168785
MESH:D005355 Fibrosis Dietary Fats 22.0618296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 22.0620067830
MESH:D005355 Fibrosis Tretinoin 22.0617994277
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.0516973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.4316417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.348708960
MESH:D005909 Glioblastoma Tretinoin 3.0517312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.7310696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2416096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2916084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.6711294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 6.6714991402 9664655
MESH:D006333 Heart Failure pirinixic acid 2.5820558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.5415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4211000095
MESH:D006529 Hepatomegaly pirinixic acid 8.6116221962 19176532 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.6115340226 16120746 12621046
MESH:D006849 Hydrocephalus Valproic Acid 4.9817688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1815340226 16959395 8697196 18606429 16354765
MESH:D006930 Hyperalgesia Tretinoin 3.2816870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.6721332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6716778211
MESH:D006943 Hyperglycemia pirinixic acid 3.2620558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.7021332399
MESH:D006973 Hypertension Cyclosporine 5.0410903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.0418670907 18850075
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.7316612254
MESH:D007021 Hypospadias Ethinyl Estradiol 3.9116569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5512013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.8417937319
MESH:D007248 Infertility, Male vinclozolin 6.8416467254
MESH:D007249 Inflammation Dietary Fats 8.5120412841
MESH:D007249 Inflammation Tamoxifen 8.5119457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.5112200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 7.4218457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 7.4216306350
MESH:D007410 Intestinal Diseases Tretinoin 3.8717994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.2116580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.2115992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5815604871
MESH:D007674 Kidney Diseases Cyclosporine 2.3818776723 10903974 8314463
MESH:D007680 Kidney Neoplasms Cyclosporine 7.5312371664
MESH:D007680 Kidney Neoplasms Tamoxifen 7.5318625569
MESH:D007938 Leukemia Tretinoin 2.8117143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.7816482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.9317596541 16294345 19850784
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 3.9317596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.2016935935 17712046 12679006 16788101 19225113 17107899 17506722 17361223 16140955 9834237 19029980 17294898 17301526 19075265 17217047 19035177 15748426 19642359 16331271 16823087 16766008 17649720 17368321 17339181 16891316
MESH:D007984 Leydig Cell Tumor vinclozolin 4.8516417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.369224671
MESH:D008064 Lipidoses Tamoxifen 3.2117567588 15342952
MESH:D008103 Liver Cirrhosis Dietary Fats 2.9218296743
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9915474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.9918564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9912878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.9918397230 16248980
MESH:D008113 Liver Neoplasms pirinixic acid 7.5015890375 20007298 16377806
MESH:D008113 Liver Neoplasms Tamoxifen 7.5016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.5016984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.1512151625
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.4017228818
MESH:D008175 Lung Neoplasms Tamoxifen 2.2718625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.2719555203 11884234
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8819428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.6711731420 19196723 14580682 19196722 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.6819453300
MESH:D008527 Medulloblastoma Tretinoin 2.8117453147
MESH:D008545 Melanoma Tamoxifen 3.3319393235 12393984
MESH:D008545 Melanoma Tretinoin 3.3316752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.3015990972
MESH:D008591 Meningomyelocele Tretinoin 4.5316940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.9216801185
MESH:D008881 Migraine Disorders Valproic Acid 3.2518803445 18765137
MESH:D009135 Muscular Diseases pirinixic acid 3.6116239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.118888407
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.5417596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 7.5417596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1719151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0812213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.0116411023
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5419410462
MESH:D009369 Neoplasms pirinixic acid 5.0317405874
MESH:D009369 Neoplasms Tretinoin 5.0316594593 16946489
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.1319196722 19189210 19200415
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3619348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.8314600291
MESH:D009421 Nervous System Malformations Tretinoin 9.839125849
MESH:D009436 Neural Tube Defects Tretinoin 7.489142499
MESH:D009436 Neural Tube Defects Valproic Acid 7.4816359493 8888407
MESH:D009765 Obesity Dietary Fats 4.4917217161 18457598 21332399 11836018 16723640 18674790 20518802 19632207 20132043
MESH:D009765 Obesity pirinixic acid 4.4920558911
MESH:D010051 Ovarian Neoplasms Tretinoin 2.3716936753
MESH:D010146 Pain Tretinoin 2.9716870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.4915976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7711578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3812520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6518163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.2912371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 16.9511896295 11222880 11118676 11399792
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 16.9520603192
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 16.9518220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.0518220299
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.9015572423
MESH:D011471 Prostatic Neoplasms Calcitriol 3.3216644109 16289102 15754350 12479363 18247401
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.3215067354
MESH:D011472 Prostatitis vinclozolin 5.0518629315
MESH:D011507 Proteinuria Tretinoin 3.6916636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.4315861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 4.6712752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.2516882103
MESH:D011625 Pterygium Tretinoin 4.9116723453
MESH:D015427 Reperfusion Injury pirinixic acid 2.4219058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9318990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 11.1616116481 16283617
MESH:D012208 Rhabdomyosarcoma Valproic Acid 11.1619155313
MESH:D012559 Schizophrenia Valproic Acid 2.0815737665 19110320
MESH:D012640 Seizures Valproic Acid 2.791511512 15475178 3137016 16876388 11044598 11738929 14763951 17978042
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.6816192470
MESH:D012878 Skin Neoplasms Tretinoin 5.6816467112
MESH:D013088 Spermatocele Ethinyl Estradiol 12.0116709447
MESH:D013088 Spermatocele Tamoxifen 12.0116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.1519457130
MESH:D016135 Spinal Dysraphism Valproic Acid 3.8419490988
MESH:D013226 Status Epilepticus Valproic Acid 4.6712833885
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.7111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0412697716
MESH:D013964 Thyroid Neoplasms Tretinoin 3.0916026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.8616051514
MESH:D014178 Translocation, Genetic Valproic Acid 5.3717262798
MESH:D014376 Tuberculosis Tretinoin 3.2716040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.643119515
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 2.3817572228 16712894 8653321
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.758888407
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.7516129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3914692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.7416752155
MESH:D014605 Uveitis Cyclosporine 4.121336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.7312125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.6214671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.1516761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3815886252
MESH:D015430 Weight Gain Dietary Fats 3.8116723640
MESH:D009396 Wilms Tumor Tretinoin 4.0416287080
MESH:D014985 Xerophthalmia Cyclosporine 4.5817120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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