AutismKB 2.0

Annotation Detail for C16orf53


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Basic Information Top
Gene Symbol:C16orf53 ( FLJ22459,GAS,MGC4606,PA1 )
Gene Full Name: chromosome 16 open reading frame 53
Band: 16p11.2
Quick LinksEntrez ID:79447; OMIM: 612033; Uniprot ID:PA1_HUMAN; ENSEMBL ID: ENSG00000185928; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of C16ORF53 mRNAdecreases expression 19150397
C011890 kojic acid kojic acid results in increased expression of C16ORF53 mRNAincreases expression 16595896
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0420889678
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1620426865
MESH:D008114 Liver Neoplasms, Experimental kojic acid 3.6018544905
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018