AutismKB 2.0

Annotation Detail for ATP13A3


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Basic Information Top
Gene Symbol:ATP13A3 ( AFURS1,DKFZp686K16189,FLJ90613 )
Gene Full Name: ATPase type 13A3
Band: 3q29
Quick LinksEntrez ID:79572; OMIM: 610232; Uniprot ID:AT133_HUMAN; ENSEMBL ID: ENSG00000133657; HGNC ID: 24113
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ATP13A3 mRNAdecreases expression 19150397
20018196
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of ATP13A3 mRNAincreases expression 15336504
C010327 salinomycin salinomycin results in decreased expression of ATP13A3 mRNAdecreases expression 19682730
D014212 Tretinoin Tretinoin results in decreased expression of ATP13A3 mRNAdecreases expression 16054129
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000505 Alopecia Tretinoin 3.9415955085
MESH:D001169 Arthritis, Experimental Tretinoin 3.3016412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.3316292516
MESH:D001249 Asthma Tretinoin 2.4316456186
MESH:D001471 Barrett Esophagus Tretinoin 4.9116935849
MESH:D001778 Blood Coagulation Disorders Tretinoin 4.0316197459 16206674
MESH:D001943 Breast Neoplasms salinomycin 2.5519682730
MESH:D001943 Breast Neoplasms Tretinoin 2.5516443354 16873071 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 5.2216813970
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.8816168501
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 1.921917145
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.3716096774 16051514
MESH:D002386 Cataract Tretinoin 3.3017460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.9820889678
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 5.2216129372
MESH:D002822 Choriocarcinoma Tretinoin 5.8816461808
MESH:D002972 Cleft Palate Tretinoin 2.809407595
MESH:D003092 Colitis Tretinoin 4.2617035595
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.839125849 14991402 17551590 9142499 10589399 9224671 8800419 9211117 9664655 16925845
MESH:D004489 Edema, Cardiac Tretinoin 5.1918230668
MESH:D016889 Endometrial Neoplasms Tretinoin 3.3516569247
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D005124 Eye Abnormalities Tretinoin 3.8716938888 9664655
MESH:D005355 Fibrosis Tretinoin 4.0717994277
MESH:D005909 Glioblastoma Tretinoin 3.2417312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.4416096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.8816084493
MESH:D006330 Heart Defects, Congenital Tretinoin 3.079664655 14991402
MESH:D006930 Hyperalgesia Tretinoin 3.5316870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 5.1316778211
MESH:D007410 Intestinal Diseases Tretinoin 4.3317994277
MESH:D007569 Jaw Abnormalities Tretinoin 4.3315992940 17551590
MESH:D007938 Leukemia Tretinoin 2.9317143497
MESH:D007951 Leukemia, Myeloid Tretinoin 4.1219285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.1216294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.3916823087 16788101 17339181 19075265 16140955 16935935 17217047 17301526 19642359 17361223 17294898 17506722 19035177 12679006 17712046 17368321 17649720 19029980 16891316 16766008 17107899 16331271 9834237 19225113 15748426
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.589224671
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 1.8116248980 18397230
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 4.0019682730
MESH:D008527 Medulloblastoma Tretinoin 2.9117453147
MESH:D008545 Melanoma Tretinoin 1.9816752155
MESH:D008591 Meningomyelocele Tretinoin 4.9916940565
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.2817596541
MESH:D009369 Neoplasms Tretinoin 2.5716594593 16946489
MESH:D009421 Nervous System Malformations Tretinoin 4.289125849
MESH:D009436 Neural Tube Defects Tretinoin 3.299142499
MESH:D010051 Ovarian Neoplasms Tretinoin 2.4416936753
MESH:D010146 Pain Tretinoin 3.2416870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5715976015
MESH:D011507 Proteinuria Tretinoin 4.0716636307
MESH:D011625 Pterygium Tretinoin 5.4216723453
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.5616283617 16116481
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 6.338532709
MESH:D012878 Skin Neoplasms Tretinoin 6.3316467112
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D013964 Thyroid Neoplasms Tretinoin 3.3316026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 4.1816051514
MESH:D014376 Tuberculosis Tretinoin 3.4516040207
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 4.0716129372
MESH:D014604 Uveal Neoplasms Tretinoin 5.3316752155
MESH:D014820 Vitiligo Tretinoin 4.5616761959
MESH:D009396 Wilms Tumor Tretinoin 4.3416287080
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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