AutismKB 2.0

Annotation Detail for SNRNP25


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Basic Information Top
Gene Symbol:SNRNP25 ( C16orf33,FLJ22940 )
Gene Full Name: small nuclear ribonucleoprotein 25kDa (U11/U12)
Band: 16p13.3
Quick LinksEntrez ID:79622; OMIM: NA; Uniprot ID:SNR25_HUMAN; ENSEMBL ID: ENSG00000161981; HGNC ID: 14161
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D004317 Doxorubicin SNRNP25 protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
D017239 Paclitaxel SNRNP25 protein affects the susceptibility to Paclitaxelaffects response to substance 16217747
C010327 salinomycin salinomycin results in decreased expression of SNRNP25 mRNAdecreases expression 19682730
D014747 Vinblastine SNRNP25 protein affects the susceptibility to Vinblastineaffects response to substance 16217747
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Doxorubicin 2.6417418594
MESH:D000419 Albuminuria Doxorubicin 5.0521441931
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 5.4214601052
MESH:D001859 Bone Neoplasms Paclitaxel 5.0315867366
MESH:D001932 Brain Neoplasms Doxorubicin 4.2017150277
MESH:D001943 Breast Neoplasms Doxorubicin 2.1916115903 15993339 11325840 16826403 17983394 15994142 16096432 17426702 19526202 15692762 17369602 18695136 18628466 15567936 15668708 18382427 15136595 16322301 18234424 16595493 15939500 16264153 15634643 16935488
MESH:D001943 Breast Neoplasms Paclitaxel 2.1918234424 16244791 18223236 15136595 16115903 16273361 18323546 11325840
MESH:D001943 Breast Neoplasms salinomycin 2.1919682730
MESH:D002276 Carcinoid Tumor Doxorubicin 5.5316051944
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 3.5616023760 18059187 17876044 16234567
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 3.5616313753
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 7.4816201981 1485588
MESH:D002292 Carcinoma, Renal Cell Vinblastine 7.481485588
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 2.726189445
MESH:D009202 Cardiomyopathies Doxorubicin 3.7716612575 16651473 17519947 16269455 18627295 15792986 17329180 15811867 16364871 16455267 17007740 17924179 17308081 16952015 17351982 16109756 15476868 16242529 17131338 15505089 17974986 16731534 17928571 17382496 16278810
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 3.0517334414 16243910
MESH:D015179 Colorectal Neoplasms Doxorubicin 3.8118259882 18802399
MESH:D015179 Colorectal Neoplasms Paclitaxel 3.8118802399
MESH:D015179 Colorectal Neoplasms Vinblastine 3.8118802399
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 2.5217416283
MESH:D004362 Drug Toxicity Doxorubicin 3.9618602426
MESH:D016889 Endometrial Neoplasms Doxorubicin 3.6917359293
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.8818037988
MESH:D004938 Esophageal Neoplasms Paclitaxel 2.9716481741
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 5.2219069698
MESH:D005909 Glioblastoma Doxorubicin 3.5917150277
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.7815692506
MESH:D006331 Heart Diseases Doxorubicin 3.7516495754 16244372 14766674 16330681 16879835 16244371 18006777 17875725 12587719 18674790 17888722 16144979 16707910
MESH:D006333 Heart Failure Doxorubicin 3.5617481944
MESH:D006394 Hemangiosarcoma Doxorubicin 4.3315692506
MESH:D006689 Hodgkin Disease Doxorubicin 9.0417606976 18501091 15147373
MESH:D006689 Hodgkin Disease Vinblastine 9.0418501091 18180244
MESH:D007674 Kidney Diseases Doxorubicin 3.2516775033 15369732 15699352
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.5816707910
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.8816085563
MESH:D008080 Liposarcoma Paclitaxel 5.2817353645
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 2.1616595196 16439617
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 3.2416842330 17085340
MESH:D008175 Lung Neoplasms Doxorubicin 2.156189445 17418594
MESH:D008223 Lymphoma Doxorubicin 3.7316098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 10.1317654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 10.1314749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 5.1315621674
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 7.3615458769
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 7.3619682730
MESH:D008545 Melanoma Doxorubicin 5.6716827129
MESH:D008545 Melanoma Paclitaxel 5.6716342250 12025231 12040289
MESH:D008545 Melanoma Vinblastine 5.6718176117 17761969 18505091 16432458 18332650 15577320 16809738 16248763 12374674 15577323
MESH:D008654 Mesothelioma Doxorubicin 3.1817638057
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.9315792986
MESH:D052016 Mucositis Doxorubicin 5.4217415656
MESH:D009101 Multiple Myeloma Paclitaxel 3.9614749477
MESH:D009203 Myocardial Infarction Doxorubicin 3.0819429709 15857846
MESH:D009362 Neoplasm Metastasis Doxorubicin 6.5618259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 6.5615867366
MESH:D009401 Nephrosis Doxorubicin 5.3316636307 16899518
MESH:D009404 Nephrotic Syndrome Doxorubicin 4.3715640375 16889571
MESH:D009447 Neuroblastoma Doxorubicin 3.4315555623
MESH:D009503 Neutropenia Vinblastine 5.0317378895
MESH:D010014 Osteolysis Paclitaxel 5.6115867366
MESH:D012516 Osteosarcoma Doxorubicin 4.4415930896
MESH:D010051 Ovarian Neoplasms Paclitaxel 3.0811161223
MESH:D003557 Phyllodes Tumor Doxorubicin 5.8817983394
MESH:D010997 Pleural Neoplasms Doxorubicin 5.8817638057
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.5216729912 15749863 15897917 18437689 16888761 16868541
MESH:D011471 Prostatic Neoplasms Paclitaxel 3.5217172428 17136230 16356831 16729912
MESH:D051437 Renal Insufficiency Doxorubicin 4.7817922066
MESH:D012509 Sarcoma Doxorubicin 4.3817203757 15625365 17710206 18313854 15675481 16767912
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.7516326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 5.4217846226
MESH:D012878 Skin Neoplasms Doxorubicin 3.1115692506
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 5.1317203757 16767912 15625365
MESH:D013274 Stomach Neoplasms Paclitaxel 2.4518396642 18506536
MESH:D024801 Tauopathies Paclitaxel 5.4416930453
MESH:D013964 Thyroid Neoplasms Doxorubicin 3.6717909728 16010429
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 2.8817653716
MESH:D014625 Vaginal Neoplasms Vinblastine 5.6115577323
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.7816364871 17678736 17638931 17334414
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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